Altered attention networks in patients with thyroid dysfunction: A neuropsychological study.

Abstract:

:Patients with thyroid dysfunction (31 hypothyroid, 32 subclinical hypothyroidism, 34 hyperthyroid, and 30 subclinical hyperthyroidism) and 37 euthyroid control subjects were recruited and performed the attention network test (ANT), which can simultaneously examine the alertness, orientation and execution control of the participants. Patients with hypothyroidism had abnormalities in the alerting network, and those with hyperthyroidism had impairments of the alerting and executive control networks. No attention networks deficit existed in patients with subclinical hyperthyroidism and subclinical hypothyroidism. The anxiety and depression scores of patients with thyroid dysfunction were significantly higher than those of the healthy control group. Covariance analysis demonstrated that interactions between group and Hamilton Anxiety Scale scores, group and HAMD score were not significant, but there was a significant main effect for group when analyzing the difference in values of the alerting network between groups. Further, the efficiency of the executive control network was negatively correlated with the T4 level in the hypothyroidism group, and positively correlated with the T4 level in the hyperthyroidism group. T4 or T3 level and efficiencies of the executive control network had a significant quadratic U-shaped relationship in all participants. In summary, the patients with four kinds of thyroid dysfunction exhibited different characteristics of ANT performance. Patients with thyroid dysfunction had various degrees of anxiety and depression disorders, but anxiety and depression disorders had no effect on the differences in the executive control network between the groups.

journal_name

Horm Behav

journal_title

Hormones and behavior

authors

Yuan L,Luan D,Xu X,Yang Q,Huang X,Zhao S,Zhang Y,Zhou Z

doi

10.1016/j.yhbeh.2020.104714

subject

Has Abstract

pub_date

2020-05-01 00:00:00

pages

104714

eissn

0018-506X

issn

1095-6867

pii

S0018-506X(20)30040-4

journal_volume

121

pub_type

杂志文章
  • Sex differences in cortisol's regulation of affiliative behavior.

    abstract::A contribution to a special issue on Hormones and Human Competition. A stress perspective is used to illuminate how competitive defeat and victory shape biology and behavior. We report a field study examining how change in cortisol following perceived defeat (vs. victory) in a competition-in this case, a dog agility c...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2016.12.005

    authors: Sherman GD,Rice LK,Jin ES,Jones AC,Josephs RA

    更新日期:2017-06-01 00:00:00

  • Variations in maternal behavior in rats selected for infant ultrasonic vocalization in isolation.

    abstract::Individual differences in maternal behavior in rodents are associated with altered physiology and behavior in offspring across their lifespan and across generations. Offspring of rat dams that engage in high frequencies of high-arched-back nursing and pup-licking (High-LG) show attenuated stress responses compared to ...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2015.08.007

    authors: Brunelli SA,Curley JP,Gudsnuk K,Champagne FA,Myers MM,Hofer MA,Welch MG

    更新日期:2015-09-01 00:00:00

  • Urinary C-peptide tracks seasonal and individual variation in energy balance in wild chimpanzees.

    abstract::C-peptide of insulin presents a promising new tool for behavioral ecologists that allows for regular, non-invasive assessment of energetic condition in wild animals. C-peptide is produced on an equimolar basis with insulin, thus is indicative of the body's response to available glucose and, with repeated measurement, ...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2008.11.005

    authors: Emery Thompson M,Muller MN,Wrangham RW,Lwanga JS,Potts KB

    更新日期:2009-02-01 00:00:00

  • Female sexual swelling size, timing of ovulation, and male behavior in wild West African chimpanzees.

    abstract::Conspicuous swellings of the perineal skin can be observed in females of many catharrine primate species particularly during the middle stages of the ovarian cycle. The functional significance of this trait remains poorly understood. Recently, two hypotheses, the "reliable indicator" hypothesis and the "graded signal"...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2004.03.013

    authors: Deschner T,Heistermann M,Hodges K,Boesch C

    更新日期:2004-08-01 00:00:00

  • Behavioral profiles and stress-induced corticosteroid secretion in male Wistar rats subjected to short and prolonged periods of maternal separation.

    abstract::Early life experiences are important for the development of neurobiobehavioral mechanisms and subsequent establishment of mental functions. In experimental animals, early life experiences can be studied using the maternal separation model. Maternal separation has been described to induce neurobiological changes and th...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2006.06.016

    authors: Roman E,Gustafsson L,Berg M,Nylander I

    更新日期:2006-12-01 00:00:00

  • Astrocytic IL-6 mediates locomotor activity, exploration, anxiety, learning and social behavior.

    abstract::Interleukin-6 (IL-6) is a major cytokine in the central nervous system, secreted by different brain cells and with roles in a number of physiological functions. We herewith confirm and expand the importance of astrocytic production of and response to IL-6 by using transgenic mice deficient in astrocytic IL-6 (Ast-IL-6...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2015.06.016

    authors: Erta M,Giralt M,Esposito FL,Fernandez-Gayol O,Hidalgo J

    更新日期:2015-07-01 00:00:00

  • The newborn rat's stress system readily habituates to repeated and prolonged maternal separation, while continuing to respond to stressors in context dependent fashion.

    abstract::Adrenal corticosterone secretion of newborn mice rapidly desensitizes to repeated maternal absence. The present study investigated the effects of novelty exposure, maternal care and genotype on this phenomenon. Maternal separation (MS) took place on postnatal days (pnd) 3-5. In Wistar rats, the degree of novelty in th...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2011.04.003

    authors: Daskalakis NP,Claessens SE,Laboyrie JJ,Enthoven L,Oitzl MS,Champagne DL,de Kloet ER

    更新日期:2011-07-01 00:00:00

  • Maternal glucocorticoid deficit affects hypothalamic-pituitary-adrenal function and behavior of rat offspring.

    abstract::Detrimental consequences of prenatal stress include increased hypothalamic-pituitary-adrenal (HPA) function, anxiety and depression-like behavior in adult offspring. To identify the role of maternal corticosterone milieu in the fetal programming of adult function, we measured these same behavioral and hormonal endpoin...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2006.11.006

    authors: Wilcoxon JS,Redei EE

    更新日期:2007-03-01 00:00:00

  • Neuroendocrine stress response is moderated by sex and sex hormone receptor polymorphisms.

    abstract::Sex hormones are significant regulators of stress reactivity, however, little is known about how genetic variation in hormone receptors contributes to this process. Here we report interactions between biological sex and repeat polymorphisms in genes encoding sex hormone receptors, and their effects on salivary cortiso...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2018.10.002

    authors: Hastings WJ,Chang AM,Ebstein RP,Shalev I

    更新日期:2018-11-01 00:00:00

  • Testosterone may increase selective attention to threat in young male macaques.

    abstract::Animal studies indicate that sex hormones have widespread effects on the brain, cognition and emotion, but findings in humans are inconsistent. Well-controlled studies in nonhuman primates are crucial to resolve these discrepancies. In this study, we examined the effects of testosterone (T) on emotion in male rhesus m...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2010.08.010

    authors: Lacreuse A,King HM,Kurdziel LB,Partan SR,Caldwell KM,Chiavetta MR,Millette MM,Meyer JS,Grow DR

    更新日期:2010-11-01 00:00:00

  • Yolk testosterone, postnatal growth and song in male canaries.

    abstract::Avian eggs contain substantial amounts of maternal yolk androgens, which have been shown to modulate offspring phenotype. The first studies on the functional consequences of maternal yolk androgens have focused on early life stages and their role in sibling competition. However, recent longitudinal studies reported lo...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2008.02.005

    authors: Müller W,Vergauwen J,Eens M

    更新日期:2008-06-01 00:00:00

  • The BB2 receptor antagonist BW2258U89 attenuates the feeding responses evoked by exogenous gastrin releasing peptide-29.

    abstract::This confirmatory work is aimed to test that the hypothesis that the gastrin releasing peptide (GRP) receptor - the BB2 receptor - is necessary for reduction of meal size (MS) and prolongation of the intermeal interval (IMI) by the small and the large forms of GRP in the rat, GRP-10 and GRP-29, and to confirm the site...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2016.06.012

    authors: Washington MC,Mhalhal TR,Sayegh AI

    更新日期:2016-09-01 00:00:00

  • Sexually active bucks are a critical social cue that activates the gonadotrope axis and early puberty onset in does.

    abstract::In rodents, early exposure to adult male is well known to induce an early puberty in females (Vandenbergh effect). This phenomenon has been less studied in other mammals. In goats, despite our extensive knowledge about the "male-effect" phenomenon in adults (i.e. ovulation induced by the introduction of the male durin...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2018.10.004

    authors: Chasles M,Chesneau D,Moussu C,Poissenot K,Beltramo M,Delgadillo JA,Chemineau P,Keller M

    更新日期:2018-11-01 00:00:00

  • Testosterone control of male courtship in birds.

    abstract::A sequence of behaviours which we call courtship initiates reproduction in a large number of species. In vertebrates, as a component of male sexual behaviour courtship is strongly influenced by testicular androgen. Here I will review some salient issues about the regulation of courtship by testosterone in birds. The f...

    journal_title:Hormones and behavior

    pub_type: 杂志文章,评审

    doi:10.1016/j.yhbeh.2008.04.004

    authors: Fusani L

    更新日期:2008-08-01 00:00:00

  • Testosterone control of male-type sexual behavior in the tammar wallaby (Macropus eugenii).

    abstract::In the tammar wallaby, Macropus eugenii, the expression of male-type sexual behavior is apparently determined by the activating effects of testicular hormones in adulthood. The incidence of male-type copulatory behavior and sexual checking behavior was compared in intact (control) males, control females, testosterone-...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1006/hbeh.1996.0049

    authors: Rudd CD,Short RV,Shaw G,Renfree MB

    更新日期:1996-12-01 00:00:00

  • Monthly patterns of testosterone and behavior in prospective fathers.

    abstract::The individual time patterns of salivary testosterone of adult healthy men, self-reported sexual behavior and their co-occurrence with regular weekly or monthly intervals were studied. Twenty-seven volunteer males (mean age 33 +/- 1 years) collected daily morning saliva over a period of 90 days. Evening questionnaires...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1006/hbeh.2002.1815

    authors: Hirschenhauser K,Frigerio D,Grammer K,Magnusson MS

    更新日期:2002-09-01 00:00:00

  • Light as a modulator of emotion and cognition: Lessons learned from studying a diurnal rodent.

    abstract::Light profoundly affects the behavior and physiology of almost all animals, including humans. One such effect in humans is that the level of illumination during the day positively contributes to affective well-being and cognitive function. However, the neural mechanisms underlying the effects of daytime light intensit...

    journal_title:Hormones and behavior

    pub_type: 杂志文章,评审

    doi:10.1016/j.yhbeh.2018.09.003

    authors: Yan L,Lonstein JS,Nunez AA

    更新日期:2019-05-01 00:00:00

  • Sex-specific hypothalamic-pituitary-gonadal axis sensitivity in migrating songbirds.

    abstract::In seasonally migratory species, the overlap between the migratory and breeding life history stages is a balance between the physiological and behavioral requirements of each stage. Previous studies investigating the degree to which songbirds prepare for breeding during spring migration have focused on either circulat...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2017.11.003

    authors: Covino KM,Jawor JM,Morris SR,Moore FR

    更新日期:2018-01-01 00:00:00

  • Divorce in the socially monogamous zebra finch: Hormonal mechanisms and reproductive consequences.

    abstract::Up to 80% of all bird species are socially monogamous. Divorce (switching partners) or pair disruption (due to the death of a partner) has been associated with decreased reproductive success, suggesting social monogamy is a strategy that may maximize fitness via coordination between partners. Previous studies have dem...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2016.11.004

    authors: Crino OL,Buchanan KL,Fanson BG,Hurley LL,Smiley KO,Griffith SC

    更新日期:2017-01-01 00:00:00

  • Photoperiod and aggression induce changes in ventral gland compounds exclusively in male Siberian hamsters.

    abstract::Chemical communication is a critical component of social behavior as it facilitates social encounters, allows for evaluation of the social partner, defines territories and resources, and advertises information such as sex and physiological state of an animal. Odors provide a key source of information about the social ...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2016.02.005

    authors: Rendon NM,Soini HA,Scotti MA,Weigel ER,Novotny MV,Demas GE

    更新日期:2016-05-01 00:00:00

  • Interface between metabolic balance and reproduction in ruminants: focus on the hypothalamus and pituitary.

    abstract::This article is part of a Special Issue "Energy Balance". The interface between metabolic regulators and the reproductive system is reviewed with special reference to the sheep. Even though sheep are ruminants with particular metabolic characteristics, there is a broad consensus across species in the way that the repr...

    journal_title:Hormones and behavior

    pub_type: 杂志文章,评审

    doi:10.1016/j.yhbeh.2014.02.005

    authors: Clarke IJ

    更新日期:2014-06-01 00:00:00

  • Role of progesterone receptors during postpartum estrus in rats.

    abstract::We studied the role of progesterone receptor (PR) in the display of female sexual behavior during postpartum estrus in rats. Adult female rats were treated with the PR antagonist, RU486 (1.25 and 5 mg), 3 h after parturition and sexual behavior was evaluated throughout the first postpartum day. Estradiol and progester...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2010.10.008

    authors: Carrillo-Martínez GE,Gómora-Arrati P,González-Arenas A,Morimoto S,Camacho-Arroyo I,González-Flores O

    更新日期:2011-01-01 00:00:00

  • Evidence for cell proliferation in the sheep brain and its down-regulation by parturition and interactions with the young.

    abstract::Production of new neurons continues throughout life in the subventricular zone (SVZ) and the dentate gyrus (DG) of the hippocampus and is influenced by both endocrine and social factors. In sheep parturition is associated with the establishment of a selective bond with the young based on an olfactory learning. The pos...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2010.07.006

    authors: Brus M,Meurisse M,Franceschini I,Keller M,Lévy F

    更新日期:2010-11-01 00:00:00

  • The effect of chronic administration of corticosterone on anxiety- and depression-like behavior and the expression of GABA-A receptor alpha-2 subunits in brain structures of low- and high-anxiety rats.

    abstract::The aim of this study was to examine changes in rat emotional behavior and determine differences in the expression of GABA-A receptor alpha-2 subunits in brain structures of low- (LR) and high-anxiety (HR) rats after the repeated corticosterone administration. The animals were divided into LR and HR groups based on th...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2013.10.011

    authors: Skórzewska A,Lehner M,Wisłowska-Stanek A,Krząścik P,Ziemba A,Płaźnik A

    更新日期:2014-01-01 00:00:00

  • Testosterone, endurance, and Darwinian fitness: natural and sexual selection on the physiological bases of alternative male behaviors in side-blotched lizards.

    abstract::The mechanistic bases of natural and sexual selection on physiological and behavioral traits were examined in male morphs of three colors of the side-blotched lizard, Uta stansburiana. Orange-throated males are aggressive and defend large territories with many females. Blue-throated males defend smaller territories wi...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1006/hbeh.2000.1622

    authors: Sinervo B,Miles DB,Frankino WA,Klukowski M,DeNardo DF

    更新日期:2000-12-01 00:00:00

  • Chemical olfactory signals and parenthood in mammals.

    abstract::This article is part of a Special Issue "Chemosignals and Reproduction". In mammalian species, odor cues emitted by the newborn are essential to establish maternal behavior at parturition and coordinate early mother-infant interactions. Offspring odors become potent attractive stimuli at parturition promoting the cont...

    journal_title:Hormones and behavior

    pub_type: 杂志文章,评审

    doi:10.1016/j.yhbeh.2014.06.018

    authors: Corona R,Lévy F

    更新日期:2015-02-01 00:00:00

  • Cloning, distribution and effects of season and nutritional status on the expression of neuropeptide Y (NPY), cocaine and amphetamine regulated transcript (CART) and cholecystokinin (CCK) in winter flounder (Pseudopleuronectes americanus).

    abstract::cDNAs encoding for neuropeptide Y (NPY), cocaine and amphetamine regulated transcript (CART) and cholecystokinin (CCK) were cloned in winter flounder, a species that undergoes a period of natural fasting during the winter. Tissue distribution studies show that these peptides are present in several peripheral tissues, ...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2009.03.002

    authors: MacDonald E,Volkoff H

    更新日期:2009-06-01 00:00:00

  • Estrogen therapy and brain muscarinic receptor density in healthy females: a SPET study.

    abstract::Estrogen Therapy (ET) may protect against age-related cognitive decline and neuropsychiatric disorders (e.g. Alzheimer's disease). The biological basis for this putative neuroprotective effect is not fully understood, but may include modulation of cholinergic systems. Cholinergic dysfunction has been implicated in age...

    journal_title:Hormones and behavior

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.yhbeh.2006.10.007

    authors: Norbury R,Travis MJ,Erlandsson K,Waddington W,Ell PJ,Murphy DG

    更新日期:2007-02-01 00:00:00

  • Behavioral and neuroendocrine actions of the Met-enkephalin-related peptide MERF.

    abstract::The effects and the mediation of the action of the proenkephalin derivative Met(5)-enkephalin-Arg(6)-Phe(7) (MERF) on the hypothalamo-pituitary-adrenal (HPA) system and open-field behavior were investigated in mice. Intracerebroventricular injection of the heptapeptide increased square crossing, rearing, and plasma co...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/s0018-506x(03)00004-7

    authors: Bujdosó E,Jászberényi M,Farkas J,Tóth G,Wollemann M,Telegdy G

    更新日期:2003-02-01 00:00:00

  • A phylogenetically controlled test of hypotheses for behavioral insensitivity to testosterone in birds.

    abstract::In most male birds that exhibit paternal care, extending the spring testosterone (T) peak throughout the breeding season reduces nestling provisioning. However, in some species, this trade-off between high T and expression of paternal care is absent. For example, during some or all of the nestling period, T did not af...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2004.10.004

    authors: Lynn SE,Walker BG,Wingfield JC

    更新日期:2005-02-01 00:00:00