Altered attention networks in patients with thyroid dysfunction: A neuropsychological study.


:Patients with thyroid dysfunction (31 hypothyroid, 32 subclinical hypothyroidism, 34 hyperthyroid, and 30 subclinical hyperthyroidism) and 37 euthyroid control subjects were recruited and performed the attention network test (ANT), which can simultaneously examine the alertness, orientation and execution control of the participants. Patients with hypothyroidism had abnormalities in the alerting network, and those with hyperthyroidism had impairments of the alerting and executive control networks. No attention networks deficit existed in patients with subclinical hyperthyroidism and subclinical hypothyroidism. The anxiety and depression scores of patients with thyroid dysfunction were significantly higher than those of the healthy control group. Covariance analysis demonstrated that interactions between group and Hamilton Anxiety Scale scores, group and HAMD score were not significant, but there was a significant main effect for group when analyzing the difference in values of the alerting network between groups. Further, the efficiency of the executive control network was negatively correlated with the T4 level in the hypothyroidism group, and positively correlated with the T4 level in the hyperthyroidism group. T4 or T3 level and efficiencies of the executive control network had a significant quadratic U-shaped relationship in all participants. In summary, the patients with four kinds of thyroid dysfunction exhibited different characteristics of ANT performance. Patients with thyroid dysfunction had various degrees of anxiety and depression disorders, but anxiety and depression disorders had no effect on the differences in the executive control network between the groups.


Horm Behav


Hormones and behavior


Yuan L,Luan D,Xu X,Yang Q,Huang X,Zhao S,Zhang Y,Zhou Z




Has Abstract


2020-05-01 00:00:00












  • Pre-pubertal gonadectomy and the social consequences of acute ethanol in adolescent male and female rats.

    abstract::It has previously been shown that pre-pubertal or adult gonadectomy (GX) increases ethanol intake in male rats. This study examined whether this sex-selective increase reflects a GX-induced maintenance in males of more adolescent-typical responsiveness to ethanol characterized by enhanced sensitivity to positive (e.g....

    journal_title:Hormones and behavior

    pub_type: 杂志文章


    authors: Morales M,Varlinskaya EI,Spear LP

    更新日期:2014-07-01 00:00:00

  • Behavioral and neuroendocrine actions of the Met-enkephalin-related peptide MERF.

    abstract::The effects and the mediation of the action of the proenkephalin derivative Met(5)-enkephalin-Arg(6)-Phe(7) (MERF) on the hypothalamo-pituitary-adrenal (HPA) system and open-field behavior were investigated in mice. Intracerebroventricular injection of the heptapeptide increased square crossing, rearing, and plasma co...

    journal_title:Hormones and behavior

    pub_type: 杂志文章


    authors: Bujdosó E,Jászberényi M,Farkas J,Tóth G,Wollemann M,Telegdy G

    更新日期:2003-02-01 00:00:00

  • Consequences of temperature-induced sex reversal on hormones and brain in Nile tilapia (Oreochromis niloticus).

    abstract::Fish present a wide variety of sex determination systems ranging from strict genetic control (genetic sex determination, GSD) to strict environmental control (environmental sex determination, ESD). Temperature is the most frequent environmental factor influencing sex determination. Nile tilapia (Oreochromis niloticus)...

    journal_title:Hormones and behavior

    pub_type: 杂志文章


    authors: Dussenne M,Gennotte V,Rougeot C,Mélard C,Cornil CA

    更新日期:2020-05-01 00:00:00

  • Plasma membrane G protein-coupled estrogen receptor 1 (GPER) mediates rapid estradiol facilitation of sexual receptivity through the orphanin-FQ-ORL-1 system in estradiol primed female rats.

    abstract::In estradiol-primed nonreceptive ovariectomized rats, activation of G protein-coupled estrogen receptor 1 (GPER) in the arcuate nucleus of the hypothalamus (ARH) rapidly facilitates sexual receptivity (lordosis). Estradiol priming activates ARH β-endorphin (β-END) neurons that then activate medial preoptic (MPN) μ-opi...

    journal_title:Hormones and behavior

    pub_type: 杂志文章


    authors: Tominna R,Chokr S,Feri M,Chuon T,Sinchak K

    更新日期:2019-06-01 00:00:00

  • Hippocampal anatomy and water maze performance are affected by neonatal cryoanesthesia in rats of both sexes.

    abstract::There is recent evidence that cryoanesthesia, commonly used during neonatal hormone manipulations (e.g., gonadectomy), has deleterious effects on the morphology of the splenium of the corpus callosum and primary visual cortex in adult rats of both sexes. (Nuñez and Juraska, 1998; Nuñez, Kim, and Juraska, 1998). In the...

    journal_title:Hormones and behavior

    pub_type: 杂志文章


    authors: Nuñez JL,Koss WA,Juraska JM

    更新日期:2000-05-01 00:00:00

  • Estrogens, estrogen receptors, and female cognitive aging: the impact of timing.

    abstract::Estrogens have been shown to be protective agents against neurodegeneration and associated cognitive decline in aging females. However, clinical data have been equivocal as to the benefits to the brain and cognition of estrogen therapy in postmenopausal women. One factor that is proposed to be critical in determining ...

    journal_title:Hormones and behavior

    pub_type: 杂志文章,评审


    authors: Daniel JM

    更新日期:2013-02-01 00:00:00

  • Female sexual attractiveness and sex recognition in leopard gecko: Males are indiscriminate courters.

    abstract::The nature and hormonal control of cues used for recognition of sex and reproductive status of conspecifics remain largely unstudied in reptiles. It has been proposed that production of a female attractiveness pheromone controlled by female ovarian hormones (and which is suppressed by male gonadal androgens) is necess...

    journal_title:Hormones and behavior

    pub_type: 杂志文章


    authors: Schořálková T,Kratochvíl L,Kubička L

    更新日期:2018-03-01 00:00:00

  • Preoptic aromatase cells project to the mesencephalic central gray in the male Japanese quail (Coturnix japonica).

    abstract::Previous tract-tracing studies demonstrated the existence of projections from the medial preoptic nucleus (POM) to the mesencephalic central gray (GCt) in quail. GCt contains a significant number of aromatase-immunoreactive (ARO-ir) fibers and punctate structures, but no ARO-ir cells are present in this region. The or...

    journal_title:Hormones and behavior

    pub_type: 杂志文章


    authors: Absil P,Riters LV,Balthazart J

    更新日期:2001-11-01 00:00:00

  • Commitment to relationships and preferences for femininity and apparent health in faces are strongest on days of the menstrual cycle when progesterone level is high.

    abstract::Previous studies of changes in women's behavior during the menstrual cycle have offered insight into the motivations underpinning women's preferences for social cues associated with possible direct benefits (e.g., investment, low risk of infection) and indirect benefits (e.g., offspring viability). Here we sought to e...

    journal_title:Hormones and behavior

    pub_type: 临床试验,杂志文章


    authors: Jones BC,Little AC,Boothroyd L,Debruine LM,Feinberg DR,Smith MJ,Cornwell RE,Moore FR,Perrett DI

    更新日期:2005-09-01 00:00:00

  • Hormonal regulation of chemosignals of female mice that elicit ultrasonic vocalizations from males.

    abstract::Two experiments examined the properties of vaginal, facial, salivary, and urinary odors from female house mice to elicit ultrasonic vocalizations from male mice. Experiment 1 demonstrated that facial and salivary secretions from hypophysectomized females were significantly less effective in eliciting ultrasonic vocali...

    journal_title:Hormones and behavior

    pub_type: 杂志文章


    authors: Byatt S,Nyby J

    更新日期:1986-03-01 00:00:00

  • Evidence for cell proliferation in the sheep brain and its down-regulation by parturition and interactions with the young.

    abstract::Production of new neurons continues throughout life in the subventricular zone (SVZ) and the dentate gyrus (DG) of the hippocampus and is influenced by both endocrine and social factors. In sheep parturition is associated with the establishment of a selective bond with the young based on an olfactory learning. The pos...

    journal_title:Hormones and behavior

    pub_type: 杂志文章


    authors: Brus M,Meurisse M,Franceschini I,Keller M,Lévy F

    更新日期:2010-11-01 00:00:00

  • Testicular hormone exposure during adolescence organizes flank-marking behavior and vasopressin receptor binding in the lateral septum.

    abstract::Adolescence is a period during which many social behaviors emerge. One such behavior, flank marking, is a testosterone-modulated scent marking behavior that communicates dominance status between adult male Syrian hamsters. Testosterone modulates flank-marking behavior by altering neural transmission of vasopressin wit...

    journal_title:Hormones and behavior

    pub_type: 杂志文章


    authors: Schulz KM,Menard TA,Smith DA,Albers HE,Sisk CL

    更新日期:2006-09-01 00:00:00

  • Primer effects by conspecific odors in house mice: a new perspective in the study of primer effects on reproductive activities.

    abstract::Half a century has passed since the first report of the influence of odors on mice. Odors are known to influence behavior (signaling effect) and affect the physiology (primer effect) of mice. This review focuses on summarizing the primer effects found so far in female and male mice. Odors from conspecifics of the oppo...

    journal_title:Hormones and behavior

    pub_type: 杂志文章,评审


    authors: Koyama S

    更新日期:2004-09-01 00:00:00

  • Androgens modulate song effort and aggression in Neotropical singing mice.

    abstract::Androgens are an important class of steroid hormones involved in modulating the expression and evolution of male secondary sex characters. Vocalizations used in the context of aggression and mate attraction are among the most elaborate and diverse androgen-dependent animal displays as reflected in a rich tradition of ...

    journal_title:Hormones and behavior

    pub_type: 杂志文章


    authors: Pasch B,George AS,Hamlin HJ,Guillette LJ Jr,Phelps SM

    更新日期:2011-01-01 00:00:00

  • Motherhood and the hormones of pregnancy modify concentrations of hippocampal neuronal dendritic spines.

    abstract::Short-term fluctuations in steroid hormones such as estradiol (E2) and progesterone (P) can affect the concentration of hippocampal dendritic spines in adult, cycling nulliparous female rats. Pregnancy is characterized by a significantly longer duration of substantially elevated E2 and P compared to the estrous cycle....

    journal_title:Hormones and behavior

    pub_type: 杂志文章


    authors: Kinsley CH,Trainer R,Stafisso-Sandoz G,Quadros P,Marcus LK,Hearon C,Meyer EA,Hester N,Morgan M,Kozub FJ,Lambert KG

    更新日期:2006-02-01 00:00:00

  • Effects of multiparity on recognition memory, monoaminergic neurotransmitters, and brain-derived neurotrophic factor (BDNF).

    abstract::Recognition memory and anxiety were examined in nulliparous (NP: 0 litters) and multiparous (MP: 5-6 litters) middle-aged female rats (12 months old) to assess possible enduring effects of multiparity at least 3 months after the last litter was weaned. MP females performed significantly better than NP females on the n...

    journal_title:Hormones and behavior

    pub_type: 杂志文章


    authors: Macbeth AH,Scharfman HE,Maclusky NJ,Gautreaux C,Luine VN

    更新日期:2008-06-01 00:00:00

  • Thinking about networks in the control of male hamster sexual behavior.

    abstract::Motivated social behaviors such as mating are controlled by a complex network of limbic nuclei. Concepts of network organization derived from computational neuroscience may aid our understanding of the links between the neuroanatomical circuitry and what is represented by the anatomy. Research in my laboratory uses ma...

    journal_title:Hormones and behavior

    pub_type: 杂志文章,评审


    authors: Wood RI

    更新日期:1997-08-01 00:00:00

  • Dynamics and determinants of glucocorticoid metabolite concentrations in wild Verreaux's sifakas.

    abstract::Glucocorticoids have wide-ranging effects on animals' behaviour, but many of these effects remain poorly understood because numerous confounding factors have often been neglected in previous studies. Here, we present data from a 2-year study of 7 groups of wild Verreaux's sifakas (Propithecus verreauxi), in which we e...

    journal_title:Hormones and behavior

    pub_type: 杂志文章


    authors: Rudolph K,Fichtel C,Heistermann M,Kappeler PM

    更新日期:2020-08-01 00:00:00

  • Dynamic regulation of brain aromatase and isotocin receptor gene expression depends on parenting status.

    abstract::Fathering behavior is critical for offspring survival in many species across diverse taxa, but our understanding of the neuroendocrine mechanisms regulating paternal care is limited in part because of the few primarily paternal species among the common animal models. However, many teleosts display primarily paternal c...

    journal_title:Hormones and behavior

    pub_type: 杂志文章


    authors: DeAngelis R,Dodd L,Snyder A,Rhodes JS

    更新日期:2018-07-01 00:00:00

  • Working memory in pregnant women: Relation to estrogen and antepartum depression.

    abstract::This article is part of a Special Issue "Estradiol and cognition". Subjective changes in concentration and memory are commonly reported by women during the second or third trimesters of pregnancy, but the nature of the problem is poorly understood. We hypothesized that these self-reports might reflect difficulties in ...

    journal_title:Hormones and behavior

    pub_type: 杂志文章


    authors: Hampson E,Phillips SD,Duff-Canning SJ,Evans KL,Merrill M,Pinsonneault JK,Sadée W,Soares CN,Steiner M

    更新日期:2015-08-01 00:00:00

  • Castration reduces male testosterone, estradiol, and territorial aggression, but not paternal behavior in biparental dwarf hamsters (Phodopus campbelli).

    abstract::Biparental male hamsters, Phodopus campbelli, act as midwives during the birth of their litter and are highly responsive to an experimentally displaced pup. They also have high peripheral concentrations of estradiol, a hormone with known roles in maternal behavior. Surgical castration during the gestation of their fir...

    journal_title:Hormones and behavior

    pub_type: 杂志文章


    authors: Hume JM,Wynne-Edwards KE

    更新日期:2005-09-01 00:00:00

  • The relationship between social status, behaviour, growth and steroids in male helpers and breeders of a cooperatively breeding cichlid.

    abstract::We tested whether subordinate helper males of the Lake Tanganyika cooperatively breeding cichlid Neolamprologus pulcher show elevated excretion levels of the stress hormone cortisol and reduced levels of 11-ketotestosterone and testosterone when living in groups with a small breeder male, compared to similar helper ma...

    journal_title:Hormones and behavior

    pub_type: 杂志文章


    authors: Bender N,Heg D,Hamilton IM,Bachar Z,Taborsky M,Oliveira RF

    更新日期:2006-08-01 00:00:00

  • Post-conception mating in wild long-tailed macaques (Macaca fascicularis): characterization, endocrine correlates and functional significance.

    abstract::In many anthropoid primates, mating activity is not restricted to the ovarian cycle but also occurs during pregnancy. Although it has been suggested that the main function of this post-conception mating is to confuse paternity, studies showing whether or not male primates can distinguish between the fertile phase of t...

    journal_title:Hormones and behavior

    pub_type: 杂志文章


    authors: Engelhardt A,Hodges JK,Heistermann M

    更新日期:2007-01-01 00:00:00

  • Perinatal exposure to estradiol masculinizes aspects of sexually dimorphic behavior and morphology in gray short-tailed opossums (Monodelphis domestica).

    abstract::The effects on adult sexually dimorphic behavior of perinatal exposure to estrogen were examined by treating male and female gray opossums with estradiol (EST), an estrogen receptor antagonist (tamoxifen:TX) or oil control (OIL) during the first week of life, a time period corresponding in this marsupial to late gesta...

    journal_title:Hormones and behavior

    pub_type: 杂志文章


    authors: Fadem BH

    更新日期:2000-02-01 00:00:00

  • Antenna contact and agonism in the male lobster cockroach, Nauphoeta cinerea.

    abstract::On any given day, about 35% of 80- to 85-day-old socially naïve male (SNM) lobster cockroaches (Nauphoeta cinerea) spontaneously adopted an aggressive posture (AP) without encountering another male [spontaneous AP (SAP)]. Although SAP SNMs showed significantly higher release of the pheromone 3-hydroxy-2-butanone (3H-2...

    journal_title:Hormones and behavior

    pub_type: 杂志文章


    authors: Chou SY,Huang ZY,Chen SC,Yang RL,Kou R

    更新日期:2007-08-01 00:00:00

  • Gonadal hormones in female rats protect against dehydration-induced memory impairments in the novel object recognition paradigm.

    abstract::Dehydration impairs cognitive performance in humans and rodents, although studies in animal models are limited. Estrogens have both protective effects on fluid regulation and improve performance in certain cognitive tasks. We, therefore, tested whether sex and gonadal hormones influence object recognition memory durin...

    journal_title:Hormones and behavior

    pub_type: 杂志文章


    authors: Santollo J,Myers KE,Rainer IL,Edwards AA

    更新日期:2019-08-01 00:00:00

  • The role of oxytocin in mating and pregnancy.

    abstract::The hormone oxytocin (OT) is released both centrally and peripherally during and after mating. Although research in humans suggests a central role in sexuality, the most reliable findings to date involve peripheral activation. This review will discuss these results and will particularly focus on understanding the most...

    journal_title:Hormones and behavior

    pub_type: 杂志文章,评审


    authors: Borrow AP,Cameron NM

    更新日期:2012-03-01 00:00:00

  • Mechanisms involved in the control of punished responding in mother rats.

    abstract::In a previous study we found that mother rats show more drinking responses than virgins in the punished drinking paradigm, an animal model for anxiety. The present investigation was carried out to determine the possible mechanisms underlying this naturally occurring anticonflict effect. In Experiment 1, we investigate...

    journal_title:Hormones and behavior

    pub_type: 杂志文章


    authors: Hansen S

    更新日期:1990-06-01 00:00:00

  • Sex differences in cortisol's regulation of affiliative behavior.

    abstract::A contribution to a special issue on Hormones and Human Competition. A stress perspective is used to illuminate how competitive defeat and victory shape biology and behavior. We report a field study examining how change in cortisol following perceived defeat (vs. victory) in a competition-in this case, a dog agility c...

    journal_title:Hormones and behavior

    pub_type: 杂志文章


    authors: Sherman GD,Rice LK,Jin ES,Jones AC,Josephs RA

    更新日期:2017-06-01 00:00:00

  • Effects of neonatal testosterone treatment on pacing behaviors and development of a conditioned place preference.

    abstract::Two experiments assessed the effects of neonatal testosterone treatment on paced mating behavior and conditioned place preference in female rats. In both experiments, females received s.c. injections of 5.0 microg testosterone propionate or oil vehicle at three days postpartum. As adults, females were ovariectomized a...

    journal_title:Hormones and behavior

    pub_type: 杂志文章


    authors: Gans S,Erskine MS

    更新日期:2003-11-01 00:00:00