Abstract:
:Motivated social behaviors such as mating are controlled by a complex network of limbic nuclei. Concepts of network organization derived from computational neuroscience may aid our understanding of the links between the neuroanatomical circuitry and what is represented by the anatomy. Research in my laboratory uses mating behavior in the male Syrian hamster as a model to elucidate how chemosensory and steroid cues are integrated in the brain. An interaction of odors and hormones is required for mating in this species. These two essential stimuli are transmitted through separate parallel pathways in the limbic system. The functional organization of the hamster mating behavior circuit is characterized by distributed representation, divergent and convergent neural pathways, and recurrent feedback. Odors and hormones have different modes of action on this neural network. While chemosensory cues stimulate the input units of the network, steroids facilitate behavior through the hidden units. In this manner, steroids appear to create a permissive environment for subsequent activation by odor cues.
journal_name
Horm Behavjournal_title
Hormones and behaviorauthors
Wood RIdoi
10.1006/hbeh.1997.1403subject
Has Abstractpub_date
1997-08-01 00:00:00pages
40-5issue
1eissn
0018-506Xissn
1095-6867pii
S0018-506X(97)91403-3journal_volume
32pub_type
杂志文章,评审abstract::Recent studies have reported that oxytocin ameliorates behavioral abnormalities in both animal models and individuals with autism spectrum disorders (ASD). However, the mechanisms underlying the ameliorating effects of oxytocin remain unclear. In this study, we examined the effects of intranasal oxytocin on impairment...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2017.09.013
更新日期:2017-11-01 00:00:00
abstract::In rats, progesterone (P) facilitates sexual receptivity by interacting with intracellular progestin receptors in the ventromedial hypothalamus (VMH). This experiment concerns whether P can also facilitate receptivity in rats by acting extragenomically within the ventral tegmental area (VTA). Ovariectomized rats (n = ...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1006/hbeh.1996.0069
更新日期:1996-12-01 00:00:00
abstract::3,4-methylenedioxymethamphetamine (MDMA) is a substituted phenethylamine that is widely abused as the street drug "ecstasy". Racemic MDMA (S,R(+/-)-MDMA) and its stereoisomers elicit complex spectrums of psychobiological, neurochemical, and hormonal effects. In this regard, recent findings demonstrated that S,R(+/-)-M...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2011.10.012
更新日期:2012-02-01 00:00:00
abstract::On any given day, about 35% of 80- to 85-day-old socially naïve male (SNM) lobster cockroaches (Nauphoeta cinerea) spontaneously adopted an aggressive posture (AP) without encountering another male [spontaneous AP (SAP)]. Although SAP SNMs showed significantly higher release of the pheromone 3-hydroxy-2-butanone (3H-2...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2007.04.013
更新日期:2007-08-01 00:00:00
abstract::The time of day at which mating occurs is dramatically different in diurnal compared to nocturnal rodents. We used a diurnal murid rodent, Arvicanthis niloticus, to determine if inverted rhythms in responsiveness to hormones contribute to this difference. Male and hormone-primed female grass rats were tested for matin...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2004.07.006
更新日期:2005-01-01 00:00:00
abstract::Male cotton-top tamarins, Saguinus oedipus, display hormonal changes associated with parenting prior to the birth of their infants. Here we examined the hormonal changes that occurred in experienced and inexperienced fathers during the postconception period, prior to the birth of infants. Noninvasive techniques were u...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1006/hbeh.2000.1617
更新日期:2000-11-01 00:00:00
abstract::Interspecific differences in the neuropeptide systems of the lateral septum (LS) often parallel differences in social behavior. In rodents, some closely related species that differ in aggressive behavior also differ according to the level of vasopressin (VP) innervation of the LS. In songbirds, the neuropeptides vasot...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2005.03.004
更新日期:2005-08-01 00:00:00
abstract::Plasma testosterone (T), prolactin (PRL), and behavior were monitored concurrently in free-living male California ground squirrels (Spermophilus beecheyi). Male plasma T peaked in January, 2-3 months after males emerged from their annual period of estivation. PRL peaked 6 to 10 weeks after T. Temporal patterns of spac...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/0018-506x(92)90028-t
更新日期:1992-03-01 00:00:00
abstract::Melatonin has been suggested to affect human emotion, but conflicting evidence exists. Therefore, we tested the effect of a single dose of a 4 mg prolonged release formulation of melatonin on a biologically based model of emotional processing. Affective modulation of acoustic white noise startle (103 dB) by emotional ...
journal_title:Hormones and behavior
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.yhbeh.2008.03.013
更新日期:2008-08-01 00:00:00
abstract::Androgen receptors are expressed in many different neuronal populations in the central nervous system where they often act as transcription factors in the cell nucleus. However, recent studies have detected androgen receptor immunoreactivity in neuronal and glial processes of the adult rat neocortex, hippocampal forma...
journal_title:Hormones and behavior
pub_type: 杂志文章,评审
doi:10.1016/j.yhbeh.2008.02.015
更新日期:2008-05-01 00:00:00
abstract::Studies reporting associations between genetic factors and mood-related traits have often been criticized (i) for failing to take into account the role of the social environment in which individuals act and (ii) for not maintaining a 'transparent narrative connection' between genes and outcomes. In a sample of adolesc...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2012.11.017
更新日期:2013-03-01 00:00:00
abstract::The influence of neonatal androgen on the potential to exhibit feminine sexual behavior was investigated. Male rats castrated on Day 0 but not those castrated on Day 4 or later showed hop/darting, ear wiggling, and lordotic behavior in response to treatment with estrogen and progesterone in adulthood at a frequency eq...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/0018-506x(88)90008-6
更新日期:1988-09-01 00:00:00
abstract::Androgens are often associated with assertive behavior; under what circumstances is this reflected in higher dominance rank? In this study of coresidential college women, androgens (total testosterone, free testosterone, and androstenedione) and estradiol were positively correlated with high self-regard in women (as m...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1006/hbeh.1995.1025
更新日期:1995-09-01 00:00:00
abstract::The effects on adult sexually dimorphic behavior of perinatal exposure to estrogen were examined by treating male and female gray opossums with estradiol (EST), an estrogen receptor antagonist (tamoxifen:TX) or oil control (OIL) during the first week of life, a time period corresponding in this marsupial to late gesta...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1006/hbeh.1999.1561
更新日期:2000-02-01 00:00:00
abstract::Attention-deficit/hyperactivity disorder (ADHD) in adults is associated with significant impairment in many life activities and may thus increase the risk of chronic stress in everyday life. We compared adults with a DSM-IV ADHD diagnosis (n=28) with healthy controls (n=28) regarding subjective stress and amounts of s...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2008.12.004
更新日期:2009-03-01 00:00:00
abstract::Extended biparental care is rare in insects but provides an excellent opportunity to investigate the interaction between the endocrine system and the physical and social environment in the regulation of this behavior. Burying beetles (Nicrophorus spp.) have facultative biparental care and depend on locating a small ve...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2003.09.012
更新日期:2004-03-01 00:00:00
abstract::Production of new neurons continues throughout life in the subventricular zone (SVZ) and the dentate gyrus (DG) of the hippocampus and is influenced by both endocrine and social factors. In sheep parturition is associated with the establishment of a selective bond with the young based on an olfactory learning. The pos...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2010.07.006
更新日期:2010-11-01 00:00:00
abstract::The transition to parenthood has been associated with declines in testosterone among partnered fathers, which may reflect males' motivation to invest in the family. Moreover, preliminary evidence has found that couples show correlations in hormone levels across pregnancy that may also be linked to fathers' preparation...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2016.07.005
更新日期:2017-04-01 00:00:00
abstract::In seasonally migratory species, the overlap between the migratory and breeding life history stages is a balance between the physiological and behavioral requirements of each stage. Previous studies investigating the degree to which songbirds prepare for breeding during spring migration have focused on either circulat...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2017.11.003
更新日期:2018-01-01 00:00:00
abstract::Seasonal changes in the length of the daily photoperiod induce significant changes in social behavior. Hamsters housed in winter-like short photoperiods (SP) can express significantly higher levels of aggression than hamsters housed in long photoperiods (LP) that mimic summer. The mechanisms responsible for increasing...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2009.08.007
更新日期:2009-10-01 00:00:00
abstract::Nitric oxide (NO) has been suggested to play a crucial role in the regulation of lordosis behavior via stimulation of guanylyl cyclase to synthesize cyclic GMP. Whalen and Lauber (1986, Neurosci. Biobehav. Rev. 10, 47-53) hypothesized that hormones and pharmacological agents known to facilitate lordosis in estrogen-pr...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1006/hbeh.1997.1413
更新日期:1997-10-01 00:00:00
abstract::Animal studies indicate that sex hormones have widespread effects on the brain, cognition and emotion, but findings in humans are inconsistent. Well-controlled studies in nonhuman primates are crucial to resolve these discrepancies. In this study, we examined the effects of testosterone (T) on emotion in male rhesus m...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2010.08.010
更新日期:2010-11-01 00:00:00
abstract::Groups of juvenile and 1-year-old male canaries were treated briefly with the vasotocin (VT) analog desGly(NH2)9d(CH2)5-[Tyr(Me)2,Thr4, Orn8]VT (dGVTA) during four time intervals between September and February. The canaries received subcutaneously testosterone-containing silastic implants at the start of the VT analog...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/0018-506x(91)90020-i
更新日期:1991-12-01 00:00:00
abstract::In men, sexual orientation correlates with an individual's number of older brothers, each additional older brother increasing the odds of homosexuality by approximately 33%. It has been hypothesized that this fraternal birth order effect reflects the progressive immunization of some mothers to Y-linked minor histocomp...
journal_title:Hormones and behavior
pub_type: 杂志文章,评审
doi:10.1006/hbeh.2001.1681
更新日期:2001-09-01 00:00:00
abstract::Male sexual behavior depends on gonadal androgens in species of all major vertebrate lineages, including reptiles. However, male sexual behavior includes distinct appetitive and consummatory phases, typically denoted as courtship and mounting, with potentially different hormonal control. Different proximate controls o...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2010.11.007
更新日期:2011-01-01 00:00:00
abstract::In recent years, there has been a notable interest in studying prey-predator relationships to develop rodent-based models for the neurobehavioral aspects of stress and emotion. However, despite the growing use of transgenic mice and results showing important differences in the behavioral responses of rats and mice, li...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2009.09.018
更新日期:2010-02-01 00:00:00
abstract::Behavioral studies of an XY gonadal dysgenetic chacma baboon under estradiol benzoate treatment were carried out. The dysgenetic individual and two ovariectomized conspecific control females were given a total of three testing series. The dysgenetic individual showed progressive success in her sexual interactions with...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/0018-506x(84)90042-4
更新日期:1984-06-01 00:00:00
abstract::The gonadal hormone testosterone (T) regulates aggression across a wide range of vertebrate species. Recent evidence suggests that the adrenal prohormone dehydroepiandrosterone (DHEA) may also play an important role in regulating aggression. DHEA can be converted into active sex steroids, such as T and estradiol (E(2)...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2009.07.004
更新日期:2009-10-01 00:00:00
abstract::Pregnancy and the postpartum period are times of profound behavioral change including alterations in cognitive function. This has been most often studied using hippocampal-dependent tasks assessing spatial learning and memory. However, less is known about the cognitive effects of motherhood for tasks that rely on area...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2016.12.015
更新日期:2017-03-01 00:00:00
abstract::Most nonhuman primate research on risk factors underlying vulnerability to stress has focused on early psychosocial experiences in various species of macaques. To test for genetic and experiential effects on emotional vulnerability in randomly bred squirrel monkeys, here we combined a paternal half-sibling analysis wi...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1006/hbeh.1999.1547
更新日期:1999-12-01 00:00:00