Antiulcer action of Sophora flavescens root and an active constituent. I.

Abstract:

:The effect of a methanol extract of Sophora flavescens root was examined on gastric ulcers induced in rats by HCl/ethanol in order to substantiate its reputed protective properties. Oral doses of 1 g/kg completely suppressed ulceration. Results suggest that oral administration of 50 mg/kg of vexibinol, a flavanol found in the extract, inhibited ulceration more effectively than spizofurone at 100 mg/kg.

journal_name

J Ethnopharmacol

authors

Yamahara J,Mochizuki M,Fujimura H,Takaishi Y,Yoshida M,Tomimatsu T,Tamai Y

doi

10.1016/0378-8741(90)90053-v

subject

Has Abstract

pub_date

1990-05-01 00:00:00

pages

173-7

issue

2

eissn

0378-8741

issn

1872-7573

pii

0378-8741(90)90053-V

journal_volume

29

pub_type

杂志文章
  • Gan-Lu-Siao-Du-yin, a prescription of traditional Chinese medicine, inhibited enterovirus 71 replication, translation, and virus-induced cell apoptosis.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Gan-Lu-Siao-Du-yin (GLSDY) is a prescription of traditional Chinese medicine. GLSDY contains 11 ingredients and is commonly used for endemic diseases. Enterovirus 71 (EV71) is an endemic disease that can cause meningoencephalitis with mortality and neurologic sequelae without any effectiv...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2016.03.034

    authors: Hsieh YJ,Yen MH,Chiang YW,Yeh CF,Chiang LC,Shieh DE,Yeh I,Chang JS

    更新日期:2016-06-05 00:00:00

  • Prevention of hepatic injury by a traditional Chinese formulation, BJ-JN, in mice treated with Bacille-Calmette-Guérin and lipopolysaccharide.

    abstract::The hepatoprotective effects of BJ-JN (a traditional Chinese formulation) were evaluated in Bacille-Calmette-Guérin and lipopolysaccharide (BCG/LPS)-induced immunological liver injury (ILI) in mice. BJ-JN (0.75, 1.5, 3 g/kg) was administered via gavage daily for 10 days. Liver index (liver weight/body weight), serum l...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2006.04.006

    authors: Zou Y,Yang Y,Li J,Li W,Wu Q

    更新日期:2006-10-11 00:00:00

  • Propolis and its constituent caffeic acid suppress LPS-stimulated pro-inflammatory response by blocking NF-κB and MAPK activation in macrophages.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Propolis is a bee product with numerous biological and pharmacological properties, such as immunomodulatory and anti-inflammatory activities. It has been used in folk medicine as a healthy drink and in food to improve health and prevent inflammatory diseases. However, little is known abou...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2013.06.004

    authors: Búfalo MC,Ferreira I,Costa G,Francisco V,Liberal J,Cruz MT,Lopes MC,Batista MT,Sforcin JM

    更新日期:2013-08-26 00:00:00

  • Efficacy of inhaled Lavandula angustifolia Mill. Essential oil on sleep quality, quality of life and metabolic control in patients with diabetes mellitus type II and insomnia.

    abstract:ETHNOPHARMACOLOGIC RELEVANCE:Lavandula angustifolia Mill (lavender) odor was traditionally used as sleep enhancer. Previous studies have shown interaction between insomnia, quality of life and control of diabetes mellitus (DM). Insomnia is suggested to increase the risk of depression and decrease the quality of life in...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2020.112560

    authors: Nasiri Lari Z,Hajimonfarednejad M,Riasatian M,Abolhassanzadeh Z,Iraji A,Vojoud M,Heydari M,Shams M

    更新日期:2020-04-06 00:00:00

  • The search for natural bioactive compounds through a multidisciplinary approach in Bolivia. Part II. Antimalarial activity of some plants used by Mosetene indians.

    abstract::Forty-six different species collected in the Mosetene ethnia, dwelling in the Andean Piedmont of Bolivia, were screened for antimalarial properties. Thirty-three extracts were screened for antimalarial activity in vitro on Plasmodium falciparum chloroquine resistant strain (Indo), and forty-seven extracts were evaluat...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(99)00096-3

    authors: Muñoz V,Sauvain M,Bourdy G,Callapa J,Rojas I,Vargas L,Tae A,Deharo E

    更新日期:2000-02-01 00:00:00

  • Magnolia officinalis (Hou Po) bark extract stimulates the Nrf2-pathway in hepatocytes and protects against oxidative stress.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The highly aromatic bark of Magnolia officinalis Rehder and EH Wilson, (magnolia bark) has been widely used in traditional Chinese medicine where it is known as Hou Po. Historically the bark of the tree has been used for treating variety of disorders the most common use of magnolia bark i...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2016.10.016

    authors: Rajgopal A,Missler SR,Scholten JD

    更新日期:2016-12-04 00:00:00

  • Pharmacological effect of prohibited combination pair Panax ginseng and Veratrum nigrum on colorectal metastasis in vitro and in vivo.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The pharmacological effect derived from herb-herb interaction is important to constitute the prescription especially in traditional oriental medicine. The relationship of two medicinal herbs is called "couplet medicinals" which is used in pair for the purpose of enhancing the therapeutic ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2018.03.036

    authors: Kee JY,Han YH,Mun JG,Um JY,Hong SH

    更新日期:2018-06-28 00:00:00

  • Evaluation of potential herb-drug interactions between oseltamivir and commonly used anti-influenza Chinese medicinal herbs.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:According to Traditional Chinese Medicine theory, influenza is categorized as a warm disease or Wen Bing. The Wen Bing formulas, such as Yin-Qiao-San and Sang-Ju-Yin, are still first-line herbal therapies in combating variant influenza virus. To continue our study on the pharmacokinetic a...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2019.112097

    authors: Zhang Y,Lyu C,Fong SYK,Wang Q,Li C,Ho NJ,Chan KS,Yan X,Zuo Z

    更新日期:2019-10-28 00:00:00

  • Melissa officinalis L. - A review of its traditional uses, phytochemistry and pharmacology.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Melissa officinalis L. is a medicinal plant that has long been used in different ethno-medical systems especially in the European Traditional Medicine and the Iranian Traditional Medicine for the treatment of several diseases. It is also widely used as a vegetable and to add flavor to dis...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jep.2016.05.010

    authors: Shakeri A,Sahebkar A,Javadi B

    更新日期:2016-07-21 00:00:00

  • Inhibition of glucose-induced vascular endothelial growth factor expression by Salvia miltiorrhiza hydrophilic extract in human microvascular endothelial cells: evidence for mitochondrial oxidative stress.

    abstract:AIM OF STUDY:Diabetes mellitus is frequently combined with vascular diseases, which are associated with the expression of vascular endothelial growth factor (VEGF). An approach that can reverse the induction of VEGF by hyperglycemia may potentially benefit the outcome of diabetic patients. Therefore, in the present stu...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2011.07.018

    authors: Qian S,Huo D,Wang S,Qian Q

    更新日期:2011-09-02 00:00:00

  • Anti-proliferative and apoptosis induction activities of extracts from Thai medicinal plant recipes selected from MANOSROI II database.

    abstract:UNLABELLED:ETHONOPHARMACOLOGICAL RELEVANCES: Traditional medicines have long been used by the Thai people. Several medicinal recipes prepared from a mixture of plants are often used by traditional medicinal practitioners for the treatment of many diseases including cancer. The recipes collected from the Thai medicinal ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2012.03.010

    authors: Manosroi J,Sainakham M,Manosroi W,Manosroi A

    更新日期:2012-05-07 00:00:00

  • Harpagide from Scrophularia protects rat cortical neurons from oxygen-glucose deprivation and reoxygenation-induced injury by decreasing endoplasmic reticulum stress.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Harpagide is the main ingredient in Scrophularia ningpoensis Hemsl which is used for the therapeutic purpose of treating encephalopathy. Harpagide has shown promise in the treatment of oxygen-glucose deprivation and reoxygenation (OGD/R)-induced brain injury. However, the underlying mecha...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2020.112614

    authors: Wang K,Lou Y,Xu H,Zhong X,Huang Z

    更新日期:2020-05-10 00:00:00

  • Hepatoprotective activity of flavonoids from Cichorium glandulosum seeds in vitro and in vivo carbon tetrachloride-induced hepatotoxicity.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Cichorium glandulosum Boiss. et Huet was used historically in Uyghur folk medicine. Its roots, seeds, and aerial parts are extensively used by Uyghur residents in Xinjiang to eliminate savda typhoid, dredge and cure obstructive jaundice variety liver disorders. AIM OF THE STUDY:To evalua...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2015.08.045

    authors: Tong J,Yao X,Zeng H,Zhou G,Chen Y,Ma B,Wang Y

    更新日期:2015-11-04 00:00:00

  • SDF7, a group of Scoparia dulcis Linn. derived flavonoid compounds, stimulates glucose uptake and regulates adipocytokines in 3T3-F442a adipocytes.

    abstract:ETHNOPHARMACOLOGY RELEVANCE:Adipocytes are major tissues involved in glucose uptake second to skeletal muscle and act as the main adipocytokines mediator that regulates glucose uptake mechanism and cellular differentiation. The objective of this study were to examine the effect of the SDF7, which is a fraction consists...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2013.09.001

    authors: Beh JE,Khoo LT,Latip J,Abdullah MP,Alitheen NB,Adam Z,Ismail A,Hamid M

    更新日期:2013-10-28 00:00:00

  • Hepatoprotective and toxicological assessment of an ethnomedicinal plant Euphorbia fusiformis Buch.-Ham.ex D.Don.

    abstract:AIM OF THE STUDY:The tubers of Euphorbia fusiformis Buch.-Ham.ex D.Don (Euphorbiaceae) are traditionally used in India by the Malayali tribes of Chitteri hills, Eastern Ghats, Tamil Nadu to treat liver disorders. The objective of the present study was to assess the hepatoprotective potential and biosafety of Euphorbia ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2009.10.012

    authors: Anusuya N,Raju K,Manian S

    更新日期:2010-02-03 00:00:00

  • Medicinal wild plant knowledge and gathering patterns in a Mapuche community from North-western Patagonia.

    abstract::Medicinal plant use has persisted as a long standing tradition in the Mapuche communities of Southern Argentina and Chile. An ethnobotanical survey was conducted in the rural Curruhuinca community located near the mountain city of San Martin de los Andes, Argentina. Semi-structured interviews were carried out on 22 fa...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2005.07.015

    authors: Estomba D,Ladio A,Lozada M

    更新日期:2006-01-03 00:00:00

  • Chinese materia medica used in medicinal diets.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Medicinal diets have a history of more than 2000 years. Locally referred to as yaoshan (Chinese: ), a medicinal diet is understood in China as a dietary product that combines herbs and food with the purpose of preventing and treating diseases or improving health under the guidance of trad...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2017.05.021

    authors: Tan F,Chen Y,Tan X,Ma Y,Peng Y

    更新日期:2017-07-12 00:00:00

  • The traditional drug Gongjin-Dan ameliorates chronic fatigue in a forced-stress mouse exercise model.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Gongjin-Dan is a representative traditional Oriental medicine herbal drug that has been used to treat chronic fatigue symptoms for several hundred years. We evaluated the anti-fatigue effects of Gongjin-Dan and the underlying mechanisms in a chronic forced exercise mouse model. METHODS A...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2015.04.001

    authors: Hong SS,Lee JY,Lee JS,Lee HW,Kim HG,Lee SK,Park BK,Son CG

    更新日期:2015-06-20 00:00:00

  • Anti-metastatic activity of Acanthopanax senticosus extract and its possible immunological mechanism of action.

    abstract::Antitumor and immunomodulatory activities of an aqueous extract (GF100) of Acanthopanax senticosus were examined. In experimental lung metastasis of colon26-M3.1 carcinoma cells, intravenous (i.v.) administration of GF100 2 days before tumor inoculation significantly inhibited lung metastasis in a dose-dependent manne...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2004.03.052

    authors: Yoon TJ,Yoo YC,Lee SW,Shin KS,Choi WH,Hwang SH,Ha ES,Jo SK,Kim SH,Park WM

    更新日期:2004-08-01 00:00:00

  • A network pharmacology approach to discover action mechanisms of Yangxinshi Tablet for improving energy metabolism in chronic ischemic heart failure.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Most cardiovascular diseases ultimately result in heart failure, an intractable problem in modern medicine. Yangxinshi tablet (YXS) is a Chinese medicine formula that is used clinically to treat coronary heart disease. However, the active compounds, potential targets, and pharmacological ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2019.112227

    authors: Wu RM,Jiang B,Li H,Dang WZ,Bao WL,Li HD,Ye G,Shen X

    更新日期:2020-01-10 00:00:00

  • Suppressive effect of Petasites japonicus extract on ovalbumin-induced airway inflammation in an asthmatic mouse model.

    abstract:AIM OF THE STUDY:Asthma is a disease marked by airway inflammation. Petasites japonicus (Pj) is known as an herb for treating asthma, oxidant stress and gastric ulcer in traditional Oriental medicine. In this study, the inhibitory effects of Pj extract on asthmatic responses were examined both in vitro and in vivo. MA...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2010.10.038

    authors: Lee JS,Yang EJ,Yun CY,Kim DH,Kim IS

    更新日期:2011-01-27 00:00:00

  • Hypoglycemic effect of Tournefortia hirsutissima L., on n-streptozotocin diabetic rats.

    abstract::The hypoglycemic effect of aqueous and butanolic extracts from Tournefortia hirsutissima (Boraginaceae) was determined on neonatal induced streptozotocin diabetic rats (n-STZ). Oral administration of water extracts at doses of 20 and 80mg/kg, and butanolic extracts (8 and 80mg/kg) significantly lowered the plasma gluc...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2007.02.020

    authors: Andrade-Cetto A,Revilla-Monsalve C,Wiedenfeld H

    更新日期:2007-05-30 00:00:00

  • Efficacy of Myrsine africana, Albizia anthelmintica and Hilderbrantia sepalosa herbal remedies against mixed natural sheep helminthosis in Samburu district, Kenya.

    abstract::Traditional livestock healers from Samburu and Turkana communities in Samburu District of Kenya were identified and recruited for participation in this study. Sheep with mixed gastrointestinal helminthosis were purchased from nomadic livestock owners in the area. Three herbal anthelmintic remedies, viz. Myrsine africa...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2003.11.007

    authors: Gathuma JM,Mbaria JM,Wanyama J,Kaburia HF,Mpoke L,Mwangi JN,Samburu and Turkana healers.

    更新日期:2004-03-01 00:00:00

  • The genus Nepeta: Traditional uses, phytochemicals and pharmacological properties.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Nepeta is a multiregional genus of the "Lamiaceae" (Labiatae or Mint) family. Species of Nepeta are a valuable part of traditional medicine and used extensively, particularly in the Himalayan region of India (Uttarakhand, Himachal Pradesh, Jammu and Kashmir, Leh-Ladakh), Pakistan (Khyber ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jep.2020.113679

    authors: Sharma A,Cooper R,Bhardwaj G,Cannoo DS

    更新日期:2021-03-25 00:00:00

  • In vitro cytotoxic, antileishmanial and antifungal activities of ethnopharmacologically selected Gabonese plants.

    abstract::Seventy-seven crude extracts from leaves and stem barks of 15 Gabonese plants used in traditional medicine were evaluated for their cytotoxic, antileishmanial and antifungal activities. Most of the extracts exhibited cytotoxic activities toward human monocytes, and most particularly the hydromethanolic 50% (v/v) fract...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2005.06.011

    authors: Lamidi M,DiGiorgio C,Delmas F,Favel A,Eyele Mve-Mba C,Rondi ML,Ollivier E,Nze-Ekekang L,Balansard G

    更新日期:2005-11-14 00:00:00

  • Ethnobotanical study of indigenous knowledge on medicinal and nutritious plants used to manage opportunistic infections associated with HIV/AIDS in western Uganda.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Traditional medicine plays an important role in the daily lives of the people of Uganda to treat a wide range of health problems. Our study presents results of an ethnobotanical inventory conducted to identify and document medicinal and nutritional plants used in the management of opportu...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2014.05.012

    authors: Mugisha MK,Asiimwe S,Namutebi A,Borg-Karlson AK,Kakudidi EK

    更新日期:2014-08-08 00:00:00

  • Antihyperglycemic and insulin secretory activity of Costus pictus leaf extract in streptozotocin induced diabetic rats and in in vitro pancreatic islet culture.

    abstract:AIM OF THE STUDY:The leaves of Costus pictus D. Don were used extensively for its antihyperglycemic activity by the people in Kerala, India. In the present study, the antihyperglycemic and insulin secretory activity of an aqueous extract of Costus pictus leaf extract was investigated in streptozotocin induced diabetic ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2009.03.026

    authors: Gireesh G,Thomas SK,Joseph B,Paulose CS

    更新日期:2009-06-25 00:00:00

  • Modulome-Fangjiome Association Study (MoFAS) Reveals Differential Target Distribution among Four Similar Fangjis (Formulas).

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Precise target distribution is a key issue for further appreciate applications of fangjis (formulas) with similar efficacy and herbal constituents to maximize efficacy and minimize toxicity. AIM OF THE STUDY:To develop an algorithm for investigating the differential target distributions ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2021.113822

    authors: Wang P,Zhou W,Liu J,Sui F,Wang Z

    更新日期:2021-01-15 00:00:00

  • Evaluation of some plants used in Turkish folk medicine against parasitic infections for their in vivo anthelmintic activity.

    abstract::Ethanolic and aqueous extracts obtained from nine plant species from seven families selected depending on their use in Turkish folk medicine, including Citrillus lanatus (Thunb.) Matsum. (seed), Jasminum fruticans L. (branches), Juniperus drupacea Labill. (fruits), Juniperus nana L. (fruit and leaves), Juniperus oxcyc...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2006.05.003

    authors: Kozan E,Küpeli E,Yesilada E

    更新日期:2006-11-24 00:00:00

  • Triptolide promotes generation of FoxP3+ T regulatory cells in rats.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Triptolide (TPT), a component of the Chinese herb Triptergium wilfordii, has potent immunosuppressive and anti-inflammatory activity and is used clinically in recipients of kidney transplantation. AIM OF THE STUDY:This work aimed to investigate the effect of TPT on the differentiation of...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2009.06.020

    authors: Zhang G,Liu Y,Guo H,Sun Z,Zhou YH

    更新日期:2009-08-17 00:00:00