Gentamicin as a bactericidal antibiotic in tissue culture.

abstract：:A method for the purification and concentration of Cytomegalovirus nucleocapsids and particles complete with envelope is described. Antibody to either nucleocapsid or envelope antigens can be detected in human sera. In patients with CMV disease the antibodies to the envelope antigen could not be detected before the 3r...

journal_title：Medical microbiology and immunology

authors： Schmitz H,Doerr HW,Obrig M

更新日期：1975-07-02 00:00:00

abstract：:A total of 603 serum samples obtained from 12 different patient and control groups, including potentially cross-reactive sera, were tested for the presence of antibodies against Kaposi's sarcoma-associated herpesvirus (KSHV, HHV-8). The assays used were an inhouse immunofluorescence test (IFT) employing latent KSHV an...

journal_title：Medical microbiology and immunology

authors： Preiser W,Szép NI,Lang D,Doerr HW,Rabenau HF

更新日期：2001-12-01 00:00:00

abstract：:The prophylactic intranasal medication with a new antiviral compound, 1-phenyl-3-(4 phenyl-2-thiazolyl) guanidine (CL 88,277) was evaluated in humans against rhinovirus 44 challenge. One ml containing 250 mg of CL 88,277 was administered to 10 seronegative volunteers three times a day plus one dose prior to the rhinov...

journal_title：Medical microbiology and immunology

authors： Togo Y,Durr FE,Laurenzana DA

更新日期：1977-05-18 00:00:00

abstract：:This is a summary of the recent work on some glycosidases of sand flies and their Leishmania parasites. Glycosidases catalyze the hydrolysis of complex sugar subunits of polysaccharides into simple sugars. Leishmania major parasites secrete chitinase and N-acetylglucosaminase, which enables them to survive in the gut ...

journal_title：Medical microbiology and immunology

authors： Jacobson RL,Schlein Y,Eisenberger CL

更新日期：2001-11-01 00:00:00

abstract：:Cytotoxic effects of a leukocidin from Fusobacterium necrophorum were demonstrated on bovine hepatic cells. The cytotoxic response was dose-dependent and could be inhibited by homologous antiserum. Scanning electron microscopy revealed damaged hepatic cell surface. These findings indicated a pathogenic role of the leu...

journal_title：Medical microbiology and immunology

authors： Ishii T,Kanoe M,Inoue T,Kai K,Blobel H

更新日期：1988-01-01 00:00:00

abstract：:Mastitis, which is generally described as an inflammation of breast tissue, is a common and debilitating disease which frequently results in the cessation of exclusive breastfeeding and affects up to 33% of lactating women. The condition is a primary cause of decreased milk production and results in organoleptic and n...

journal_title：Medical microbiology and immunology

authors： Angelopoulou A,Field D,Ryan CA,Stanton C,Hill C,Ross RP

更新日期：2018-04-01 00:00:00

abstract：:Upon infection of human T-cell leukemia virus type I (HTLV-I)-carrying human T-cell lines such as MT-4, HTLV-III, a probable etiologic agent of acquired immune deficiency syndrome (AIDS) caused fast and strong cytopathic effects leading ultimately to the death of the cells. Such effects were preceded by the rapid indu...

journal_title：Medical microbiology and immunology

authors： Nakashima H,Koyanagi Y,Harada S,Yamamoto N

更新日期：1986-01-01 00:00:00

abstract：:The rapid and correct identification of pathogens is of paramount importance for the treatment of patients with invasive infections. Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) can speed up the identification of bacteria and fungi and has quickly been embraced by medical...

journal_title：Medical microbiology and immunology

authors： Hamprecht A,Christ S,Oestreicher T,Plum G,Kempf VA,Göttig S

更新日期：2014-04-01 00:00:00

abstract：:The Enders strain of mumps virus grown in ovo was purified by differential and equilibrium sucrose gradient sedimentation. Purified virus contained seven polypeptides of mol. wts 68,000, 66,000, 61,000, 54,000, 52,000, 49,000, 47,000. Nucleocapsids isolated from DOC-treated virus contained two polypeptides of mol. wts...

journal_title：Medical microbiology and immunology

authors： Huppertz HI,Hall WW,ter Meulen V

更新日期：1977-12-27 00:00:00

abstract：:The ability of polymorphonuclear leucocytes (PMNs) from elderly healthy subjects and post-operative cancer patients to ingest and kill Clostridium difficile was studied. The percentage of phagocytosis in clinically healthy subjects aged 69-82 years ranged from 20.2 +/- 3.2 (mean +/- SD) to 34.1 +/- 4.2, depending on t...

journal_title：Medical microbiology and immunology

authors： Bassaris HP,Lianou PE,Legakis NJ,Papavassiliou JT

更新日期：1984-01-01 00:00:00

abstract：:Varicella during pregnancy can be associated with severe illnesses for both the mother and her neonate. Varicella pneumonia must be regarded as a medical emergency, since pregnant women are at risk of life-threatening ventilatory compromise and death. After maternal chickenpox in the first and second trimesters, conge...

journal_title：Medical microbiology and immunology

authors： Sauerbrei A,Wutzler P

更新日期：2007-06-01 00:00:00

abstract：:IgG subclass antibodies to Pseudomonas aeruginosa outer membrane proteins (OMP) were investigated in serum from cystic fibrosis (CF) patients by immunoblotting and enzyme-linked immunosorbent assay (ELISA). Fifteen patients (eight in good and seven in poor clinical condition) have been followed for an average of 13 ye...

journal_title：Medical microbiology and immunology

authors： Pressler T,Kronborg G,Shand GH,Mansa B,Høiby N

更新日期：1992-01-01 00:00:00

abstract：:Phosphorylcholine (ChoP) is covalently incorporated into bacterial surface structures, contributing to host mimicry and promoting adhesion to surfaces. Our aims were to determine the frequency of ChoP display among Aggregatibacter actinomycetemcomitans strains, to clarify which surface structures bear ChoP, and whethe...

journal_title：Medical microbiology and immunology

authors： Ihalin R,Zhong D,Karched M,Chen C,Asikainen S

更新日期：2018-11-01 00:00:00

abstract：:Both humoral and cell-mediated immune responses were studied in reactivated toxoplasma infection in mice. The infection was established by immunosuppressing chronically infected animals by thymectomy followed by irradiation. The reactivated infection was confirmed by reappearance of toxoplasma tachyzoites in peritonea...

journal_title：Medical microbiology and immunology

authors： Goyal M,Ganguly NK,Mahajan RC

更新日期：1989-01-01 00:00:00

abstract：:IgG responses are fundamental to adaptive immunity and document immunological memory of previous pathogen encounter. While specific antigen recognition is mediated by the variable F(ab')2 domain of IgG, various effector functions become activated via the constant Fcγ part bridging IgG-opsonized targets to FcγR-express...

journal_title：Medical microbiology and immunology

authors： Corrales-Aguilar E,Trilling M,Reinhard H,Falcone V,Zimmermann A,Adams O,Santibanez S,Hengel H

更新日期：2016-10-01 00:00:00

abstract：:Killer cell immunoglobulin like receptors (KIRs) have a principal role in regulating the effector functions of NK cells, particularly in viral infections. The major ligands for KIRs are human leukocyte antigen (HLA) class I molecules. The aim of this study is to investigate the possible association of KIR genes, their...

journal_title：Medical microbiology and immunology

authors： Shah-Hosseini A,Jafari M,Mohammadi A,Sanaei R,Alavian SM,Doosti-Irani A,Nooradeh Keykavousi M,Tajik N

更新日期：2017-12-01 00:00:00

abstract：:In a randomized, placebo-controlled trial in Ghana, 67 onchocerciasis patients received 200-mg/day doxycycline for 4-6 weeks, followed by ivermectin (IVM) after 6 months. After 6-27 months, efficacy was evaluated by onchocercoma histology, PCR and microfilariae determination. Administration of doxycycline resulted in ...

journal_title：Medical microbiology and immunology

authors： Hoerauf A,Specht S,Büttner M,Pfarr K,Mand S,Fimmers R,Marfo-Debrekyei Y,Konadu P,Debrah AY,Bandi C,Brattig N,Albers A,Larbi J,Batsa L,Taylor MJ,Adjei O,Büttner DW

更新日期：2008-09-01 00:00:00

abstract：:The effect of red blood cell age on the susceptibility towards NDV- induced hemolysis has been investigated. It was found that young sheep red blood cells (SRBC), although more resistant to hypotonic hemolysis, are more susceptible towards viral hemolysis than older cells. This may be because young red blood cells hav...

journal_title：Medical microbiology and immunology

authors： Sziegoleit A,Füssle R,Wellensiek HJ

更新日期：1980-01-01 00:00:00

abstract：:Interactions of virulent Leptospira interrogans with murine monocyte-macrophage-like J774A.1 cells and Vero (African green monkey kidney fibroblasts) cells from attachment to internalization were investigated by a series of morphological analysis. Fontana silver staining revealed that only the pathogenic leptospires w...

journal_title：Medical microbiology and immunology

authors： Liu Y,Zheng W,Li L,Mao Y,Yan J

更新日期：2007-12-01 00:00:00

abstract：:It is known that tetraspanin proteins are involved in many physiological somatic cell mechanisms. Additionally, research has indicated they also have a role in various infectious diseases and cancers. This review focuses on the molecular interactions underlying the tetraspanin web formation in gametes. Primarily, tetr...

journal_title：Medical microbiology and immunology

authors： Jankovičová J,Neuerová Z,Sečová P,Bartóková M,Bubeníčková F,Komrsková K,Postlerová P,Antalíková J

更新日期：2020-08-01 00:00:00

abstract：:A set of 12 rapid biochemical tests--lysinedecarboxylase, ornithinedecarboxylase, beta-galactosidase, urease, hydrogensulphide, indole, acetoin, deoxyribonuclease, esculin, mannitol, raffinose and sorbitol--were selected from an original set of 13 tests and were found to give 98% accurate reactions within 4 hrs of inc...

journal_title：Medical microbiology and immunology

authors： Nord C-E,Linberg AA,Dahlbäck A

更新日期：1975-09-19 00:00:00

abstract：:Several lines of evidence suggest a viral infection as the initiating event for the development of myocarditis (MC). Especially enteroviruses like coxsackie B3 virus have been shown to induce MC in humans and strains of MC-prone mice after an infection. The further course of the disease is, however, determined not onl...

journal_title：Medical microbiology and immunology

authors： Schwimmbeck PL,Bigalke B,Schulze K,Pauschinger M,Kühl U,Schultheiss HP

更新日期：2004-05-01 00:00:00

abstract：:The fatal inhalation infection caused by Bacillus anthracis results from a complex pathogenic cycle involving release of toxins by bacteria that germinate from spores. Currently available vaccines against anthrax consist of protective antigen (PA), one of the anthrax toxin components. However, these PA-based vaccines ...

journal_title：Medical microbiology and immunology

authors： Sinha K,Bhatnagar R

更新日期：2013-04-01 00:00:00

abstract：:Surface proteins of nine Campylobacter jejuni strains belonging to three different serovia were extracted with lysozyme/ethylenediamine-tetraacetic acid. The preparations bound to isolated murine small intestinal cells and to a membrane fraction (MF) of isolated brush borders obtained by detergent treatment with Trito...

journal_title：Medical microbiology and immunology

authors： Moser I,Hellmann E

更新日期：1989-01-01 00:00:00

abstract：:The improved Auxotab Enteric I System was re-evaluated and found to correlate 98% with conventional methods for the identification of Enterobacteriaceae. Possible Reasons for previous poor results with this system are discussed. ...

journal_title：Medical microbiology and immunology

authors： Braune LM,Kocka FE

更新日期：1975-07-02 00:00:00

abstract：:In resource-limited or point-of-care settings, rapid diagnostic tests (RDTs), that aim to simultaneously detect HIV antibodies and p24 capsid (p24CA) antigen with high sensitivity, can pose important alternatives to screen for early infections. We evaluated the performance of the antibody and antigen components of the...

journal_title：Medical microbiology and immunology

authors： Wratil PR,Rabenau HF,Eberle J,Stern M,Münchhoff M,Friedrichs I,Stürmer M,Berger A,Kuttner-May S,Münstermann D,Lucht A,Meixenberger K,Bannert N,Keppler OT

更新日期：2020-04-01 00:00:00

abstract：:The present study analyses the susceptibility of human bladder-derived cells (HT-1376) to the infection by herpes simplex virus type 2 (HSV-2) and Chlamydia trachomatis, as well as to the adhesiveness of uropathogenic bacteria. HT-1376 cells were efficiently infected by HSV-2 strain 333, as demonstrated by immunofluor...

journal_title：Medical microbiology and immunology

authors： Superti F,Longhi C,Di Biase AM,Tinari A,Marchetti M,Pisani S,Gallinelli C,Chiarini F,Seganti L

更新日期：2001-09-01 00:00:00

abstract：:Leprosy is a chronic infectious disease caused by Mycobacterium leprae. Previous studies have demonstrated that the difference among clinical forms of leprosy can be associated with the immune response of patients, mainly by T helper (Th) and regulatory T cells (Tregs). Then, aiming at clarifying the immune response, ...

journal_title：Medical microbiology and immunology

authors： Azevedo MCS,Marques H,Binelli LS,Malange MSV,Devides AC,Silva EA,Fachin LRV,Ghidella CC,Soares CT,Garlet GP,Rosa PS,Belone AFF,Trombone APF

更新日期：2017-12-01 00:00:00

abstract：:Adaptation of Borrelia burgdorferi in the vector and vertebrate host is mediated by mechanisms that regulate differential expression of outer surface lipoproteins (Osps). In this study, real time PCR was applied to quantify tissue-specific expression of four linear plasmid (lp54)-encoded (ospA, zs7.a36, zs7.a66 zs7.a6...

journal_title：Medical microbiology and immunology

authors： Lederer S,Brenner C,Stehle T,Gern L,Wallich R,Simon MM

更新日期：2005-01-01 00:00:00

abstract：:Lactoferrin (Lf) is an iron-binding protein which plays an important role in the host defense systems of different mucosal surfaces including the intestinal mucosa. In the present research the role of apo-Lf and iron-saturated Lf in the invasion process of enteroinvasive bacteria, grown in iron stress or excess, was i...

journal_title：Medical microbiology and immunology

authors： Longhi C,Conte MP,Seganti L,Polidoro M,Alfsen A,Valenti P

更新日期：1993-03-01 00:00:00