Abstract:
RATIONALE AND OBJECTIVES:The aim of this study is to assess the usefulness of computer-aided three-dimensional (3D) measurement of volume and computed tomography (CT) attenuation values of nodes for diagnosing nodal metastases of lung cancer. MATERIALS AND METHODS:We measured three diameters, their ratios, volume, and CT values in 3D images of 191 nodes (64 malignant; 162 of <1 cm in short diameter) in 26 consecutive patients who underwent contrast-enhanced, thin-section, multidetector row CT before surgery. We separately studied statistically significant factors in a group of all nodes and in another group of nodes of <1 cm in short diameter with logistic modeling and evaluated their diagnostic accuracy. RESULTS:Significant factors were CT values (P < .001) and short diameter (P = .001) for the total node group, and CT values (P = .030) and 3D volume (P = .035) for the <1 cm node group. Optimal 83% accuracy was obtained with a criterion of short diameter of >7.4 mm and CT values of >103 Hounsfield unit (HU) for the total node group, whereas optimal 76% accuracy was obtained with a criterion of 3D volume of >1282 mm(3) or CT values of >103 HU for the <1 cm node group. CONCLUSION:3D measurement may be useful for diagnosing nodal metastases.
journal_name
Acad Radioljournal_title
Academic radiologyauthors
Takahashi Y,Takashima S,Hakucho T,Miyake C,Morimoto D,Jiang BH,Numasaki H,Tomita Y,Nakanishi K,Higashiyama Mdoi
10.1016/j.acra.2013.01.013subject
Has Abstractpub_date
2013-06-01 00:00:00pages
740-5issue
6eissn
1076-6332issn
1878-4046pii
S1076-6332(13)00035-4journal_volume
20pub_type
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