Abstract:
RATIONALE AND OBJECTIVES:To compare the performance of two shortened breast magnetic resonance imaging (MRI) protocols to a standard MRI protocol for breast cancer screening. MATERIALS AND METHODS:In this Health Insurance Portability and Accountability Act compliant, institutional review board-approved pilot study, three fellowship-trained breast imagers evaluated 48 breast MRIs (24 normal, 12 benign, and 12 malignant) selected from a high-risk screening population. MRIs were presented in three viewing protocols, and a final Breast Imaging-Reporting and Data System assessment was recorded for each case. The first shortened protocol (abbreviated 1) included only fat-saturated precontrast T2-weighted, precontrast T1-weighted, and first pass T1-weighted postcontrast sequences. The second shortened protocol (abbreviated 2) included the abbreviated 1 protocol plus the second pass T1-weighted postcontrast sequence. The third protocol (full), reviewed after a 1-month waiting period, included a nonfat-saturated T1-weighted sequence, fat-saturated T2-weighted, precontrast T1-weighted, and three or four dynamic postcontrast sequences. Interpretation times were recorded for the abbreviated 1 and full protocols. Sensitivity and specificity were compared via a chi-squared analysis. This pilot study was designed to detect a 10% difference in sensitivity with a power of 0.8. RESULTS:There was no significant difference in sensitivity between the abbreviated 1 (86%; P = .22) or abbreviated 2 (89%; P = .38) protocols and the full protocol (95%). There was no significant difference in specificity between the abbreviated 1 (52%; P = 1) or abbreviated 2 (45%; P = .34) protocols and the full protocol (52%). The abbreviated 1 and full protocol interpretation times were similar (2.98 vs. 3.56 minutes). CONCLUSIONS:In this pilot study, reader performance comparing two shortened breast MRI protocols to a standard protocol in a screening cohort were similar, suggesting that a shortened breast MRI protocol may be clinically useful, warranting further investigation.
journal_name
Acad Radioljournal_title
Academic radiologyauthors
Grimm LJ,Soo MS,Yoon S,Kim C,Ghate SV,Johnson KSdoi
10.1016/j.acra.2015.06.004subject
Has Abstractpub_date
2015-09-01 00:00:00pages
1157-62issue
9eissn
1076-6332issn
1878-4046pii
S1076-6332(15)00250-0journal_volume
22pub_type
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journal_title:Academic radiology
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pub_type: 临床试验,杂志文章
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pub_type: 杂志文章,meta分析,评审
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更新日期:2011-10-01 00:00:00
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doi:10.1016/j.acra.2004.01.005
更新日期:2004-06-01 00:00:00
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journal_title:Academic radiology
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journal_title:Academic radiology
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更新日期:2014-04-01 00:00:00
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更新日期:1997-08-01 00:00:00
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更新日期:2019-10-01 00:00:00
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journal_title:Academic radiology
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