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The potential of sodium glucose cotransporter 2 (SGLT2) inhibitors to reduce cardiovascular risk in patients with type 2 diabetes (T2DM).

Abstract：

:Type 2 diabetes mellitus (T2DM) significantly increases morbidity and mortality from cardiovascular disease (CVD). Treatments for patients with T2DM have the potential to reduce cardiovascular (CV) risk. This review focuses on the potential of a new class of antidiabetic agents, the sodium glucose cotransporter 2 (SGLT2) inhibitors, to reduce CV risk in patients with T2DM through reductions in hyperglycemia, blood pressure (BP), and body weight. The results of clinical trials of SGLT2 inhibitors are summarized and discussed.

journal_name

J Diabetes Complications

journal_title

Journal of diabetes and its complications

authors

Basile JN

doi

10.1016/j.jdiacomp.2012.12.004

subject

Has Abstract

pub_date

2013-05-01 00:00:00

pages

280-6

issue

3

eissn

1056-8727

issn

1873-460X

pii

S1056-8727(12)00341-8

journal_volume

27

pub_type

杂志文章,评审

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