Expression of the HML-1 Epitope on Human Monocytes is Independent of αE Integrin mRNA.

abstract：:Although glucocorticoids (GCs) are effective in inducing remission in systemic lupus erythematosus (SLE) patients, there is a significant variation in response to therapeutic GCs, and some patients do not achieve full remission. The aim of this study was to explore the impact of environmental factors on the efficacy o...

journal_title：Inflammation

authors： Zou YF,Xu JH,Tao JH,Xu SQ,Liu S,Chen SY,Cai J,Lian L,Chen PL,Wang DG,Liu SX,Liang CM,Ye QL,Tian G,Wu M,Pan HF,Pan FM,Su H,Ye DQ

更新日期：2013-12-01 00:00:00

abstract：:Karyopherin-α2 (KPNA2) functions as an adaptor that transports several proteins to the nucleus. We investigated the function and possible mechanisms of KPNA2 involved in rheumatoid arthritis (RA). Western blotting and immunohistochemistry showed the protein expression of KPNA2 increased in synovial tissue of RA patien...

journal_title：Inflammation

authors： Liu Z,Zhang D,Sun C,Tao R,Xu X,Xu L,Cheng H,Xiao M,Wang Y

更新日期：2015-12-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is an autoimmune and inflammatory disease with strong genetic influence, especially upon immune response components. Several cytokines from the toll-like receptors activation pathway display recognized role for RA establishment. However, few studies have verified the role of key mediators suc...

journal_title：Inflammation

authors： Gomes da Silva IIF,Lima CAD,Silva JEA,Rushansky E,Mariano MHQA,Rolim P,Oliveira RDR,Louzada-Júnior P,Souto FO,Crovella S,de Azevêdo Silva J,Sandrin-Garcia P

更新日期：2021-01-06 00:00:00

abstract：:Thermal injury in rats leads to an impairment of polymorphonuclear leukocyte (PMN) functions, particularly oxidative metabolism and phosphoinositide turnover. As prostaglandin E2, which has immunosuppressive properties, is released in high levels after burn trauma, we investigated the in vitro and in vivo effects of a...

journal_title：Inflammation

authors： Tissot M,Roch-Arveiller M,Fontagne J,Giroud JP

更新日期：1992-12-01 00:00:00

abstract：:The molecular mechanisms of innate immunity are closely associated with the development of non-alcoholic fatty liver disease (NAFLD). TNF-α is a key cytokine involved in the pathogenesis of metabolic inflammation like NAFLD. Melanoma differentiation-associated gene 5 (MDA5) is a member of the intracellular RNA helicas...

journal_title：Inflammation

authors： Kawaguchi S,Sakuraba H,Haga T,Matsumiya T,Seya K,Endo T,Sawada N,Iino C,Kikuchi H,Hiraga H,Fukuda S,Imaizumi T

更新日期：2019-12-01 00:00:00

abstract：:Cyanidin-3-O-glucoside (C3G), an anthocyanin belonging to the flavonoid family and commonly present in food and vegetables in human diet, has exhibited anti-inflammatory and anti-oxidant effects. This study aimed to investigate the protective ability of C3G against inflammatory and oxidative injuries, as well as to cl...

journal_title：Inflammation

authors： Ma MM,Li Y,Liu XY,Zhu WW,Ren X,Kong GQ,Huang X,Wang LP,Luo LQ,Wang XZ

更新日期：2015-08-01 00:00:00

abstract：:Prostaglandin production was studied in cultures of pig aorta endothelial cells using radioimmunoassay, radiochromatography, and smooth muscle bioassay. PGE2 was produced in higher concentrations than other prostaglandins. Bradykinin produced a rapid dose-related stimulation of PGE2 production. These results provided ...

journal_title：Inflammation

authors： Jose PJ,Page DA,Wolstenholme BE,Williams TJ,Dumonde DC

更新日期：1981-12-01 00:00:00

abstract：:Asthma is the most common chronic disease of childhood, chronic airway inflammation; bronchial tissue fibrosis, is a pathological feature common to children asthma, and an emerging data has indicted that autophagy plays critical roles in airway inflammation and fibrosis-mediated airway remodeling. The aim of this stud...

journal_title：Inflammation

authors： Li BB,Chen YL,Pang F

更新日期：2020-02-01 00:00:00

abstract：:Dialysate and serum levels of granulocyte-colony stimulating factor (G-CSF), granulocyte macrophage colony stimulating factor (GM-CSF) and leukemia inhibitory factor (LIF) were analyzed in patients with continuous ambulatory peritoneal dialysis (CAPD). Samples from the peritoneal effluent and from serum were obtained ...

journal_title：Inflammation

authors： Brauner A,Hylander B,Lu Y

更新日期：1998-08-01 00:00:00

abstract：:Extracellular phospholipase A2 (PLA2) activity was detected in exudate from rat carrageenan-induced pleurisy using [3H]oleic acid-labeled Escherichia coli as substrate. Both exudate volume and PLA2 activity increased up to 24 h after carrageenin injection. Specific absorption of this activity by anti-group II PLA2 (PL...

journal_title：Inflammation

authors： Tanaka K,Kato T,Matsumoto K,Yoshida T

更新日期：1993-04-01 00:00:00

abstract：:The respiratory epithelium is often exposed to oxidant gases, including ozone from photochemical smog and toxic oxygen metabolites released from neutrophils recruited in conditions of airway inflammation. We evaluated DNA single strand break formation by alkaline elution as a measure of oxidant-induced DNA damage to b...

journal_title：Inflammation

authors： McDonald RJ,Pan LC,St George JA,Hyde DM,Ducore JM

更新日期：1993-12-01 00:00:00

abstract：:Human neutrophils were demonstrated to possess interleukin-2 receptor (IL-2R) beta and gamma chains, not alpha chain and the binding of IL-2 to the IL-2R beta chain on neutrophils plays an important regulatory role in neutrophil functions. We have investigated in this study the hypothesis that recombinant human IL-2 (...

journal_title：Inflammation

authors： Li J,Gyorffy S,Lee S,Kwok CS

更新日期：1996-08-01 00:00:00

abstract：:Periodontitis has been advocated as a systematic chronic low-grade infection burden. However, the relationship between periodontitis and bone defect healing has not been elucidated. One hundred and eight male Wister rats were randomly assigned into three groups: control (healthy) group, periodontitis group, and period...

journal_title：Inflammation

authors： Zhou R,Shen L,Yang C,Wang L,Guo H,Yang P,Song A

更新日期：2018-06-01 00:00:00

abstract：:Rheumatoid synovial fluids generated significantly greater amounts of superoxide, lysosomal enzymes, and superoxide dismutase from neutrophils into extracellular fluid than osteoarthritic synovial fluids. Rheumatoid factors isolated from serum suppressed superoxide-generating activity of performed immune complexes, bu...

journal_title：Inflammation

authors： Shingu M,Todoroki T,Nobunaga M

更新日期：1987-06-01 00:00:00

abstract：:Protamine sulfate induces enzyme secretion from rabbit neutrophils. Enzyme secretion is mainly due to exocytosis but, depending on the experimental conditions, a small amount of cytolysis may occur. As compared with stimulation of neutrophil functions by other activators, protamine sulfate-induced enzyme release by ex...

journal_title：Inflammation

authors： Elferink JG,Deierkauf M

更新日期：1986-12-01 00:00:00

abstract：:Paeonol, a major ingredient isolated from Moutan Cort, has various pharmacological effects. Our previous studies have shown that paeonol can exert antioxidant and anti-inflammatory therapeutic effects on ethanol-induced experimental gastric ulcer (GU). Therefore, in this study, we designed two GU models in rats induce...

journal_title：Inflammation

authors： Guo Y,Du Y,Xie L,Pu Y,Yuan J,Wang Z,Zhang T,Wang B

更新日期：2020-12-01 00:00:00

abstract：:Endothelial activation with excessive recruitment and adhesion of immune cells plays a central role in the progression of sepsis. We established a microfluidic system to study the activation of human umbilical vein endothelial cells by conditioned medium containing plasma from lipopolysaccharide-stimulated whole blood...

journal_title：Inflammation

authors： Eichhorn T,Rauscher S,Hammer C,Gröger M,Fischer MB,Weber V

更新日期：2016-10-01 00:00:00

abstract：:Ziprasidone (ZIP) is an effective antipsychotic with low side effects than other second-generation antipsychotics. Despite this, there are reports of adverse events and previous studies associating the use of ZIP the inflammatory response. It is possible to infer that bioactive molecules present in some foods could at...

journal_title：Inflammation

authors： Duarte T,Barbisan F,da Cunha BSN,Azzolin VF,Turra BO,Duarte MMMF,da Cruz Jung IE,Ribeiro EE,do Prado-Lima PA,da Cruz IBM

更新日期：2019-06-01 00:00:00

abstract：:Induction of hypoxia for 2.5 h in perfused cat livers resulted in a 10-fold increase in cathepsin D and a 15-fold increase in lactic dehydrogenase (LDH) activities in the perfusate and a 42% depression of the clearance rate of particles by the reticuloendothelial system (RES). Addition of 10(-3) M methylprednisolone (...

journal_title：Inflammation

authors： Carlson RP,Lefer AM

更新日期：1976-12-01 00:00:00

abstract：:Interactions of macrophages with epithelium represent one of the pathways involved in regulating local immune mechanisms. We studied the effect of cell-cell contact with an epithelial monolayer on the phenotype of macrophages. Human monocytes and THP-1 macrophages were co-cultured with monolayers of human bronchial ep...

journal_title：Inflammation

authors： Striz I,Slavcev A,Kalanin J,Jaresová M,Rennard SI

更新日期：2001-08-01 00:00:00

abstract：:Streptococcus suis serotype 2 (SS2) is an emerging zoonosis, and meningitis is the most frequent clinical manifestation, but mechanism of its virulent factor, enolase (Eno), is unknown in meningitis. In this study, Eno was inducibly expressed and added to an in vitro Transwell co-culture model of the blood-brain barri...

journal_title：Inflammation

authors： Sun Y,Li N,Zhang J,Liu H,Liu J,Xia X,Sun C,Feng X,Gu J,Du C,Han W,Lei L

更新日期：2016-04-01 00:00:00

abstract：:Release and activation of pro-inflammatory mediators are among the most important induced factors that are involved in the scorpion envenomation pathogenesis. Inflammatory response and lung reactivity were studied in mice following subcutaneous injection with Androctonus australis hector (Aah) venom. Venom immunodetec...

journal_title：Inflammation

authors： Adi-Bessalem S,Mendil A,Hammoudi-Triki D,Laraba-Djebari F

更新日期：2012-04-01 00:00:00

abstract：:A variety of steroidal and nonsteroidal antiinflammatory agents (NSAs) were compared for their effectiveness against a developing acute inflammatory reaction. Only BW 755C [3-amino-1-(m-trifluoromethyl)-phenyl-2-pyrazole] was immediately effective when administered 2 h after carrageenin, as the 3-h swelling was signif...

journal_title：Inflammation

authors： Holsapple MP,Yim GK

更新日期：1984-09-01 00:00:00

abstract：:C3b receptor (CR1) expression by neutrophils (PMNs) and erythrocytes (Es) from patients with chronic granulomatous disease (CGD) or with hyper-IgE, frequent infection (Job's) syndrome was compared with that of control subjects. The control subjects consisted of one group of patients with infections and a second group ...

journal_title：Inflammation

authors： Gaither TA,Gallin JI,Iida K,Nussenzweig V,Frank MM

更新日期：1984-12-01 00:00:00

abstract：:Tissue macrophages can be activated by endogenous danger signals released from cells that are stressed or injured, leading to infiltration of inflammatory macrophages and neutrophils. We postulated that macrophage-related markers might be closely associated with the existence of endogenous danger signals, reflecting o...

journal_title：Inflammation

authors： Hayashi Y,Hanawa H,Jiao S,Hasegawa G,Ohno Y,Yoshida K,Suzuki T,Kashimura T,Obata H,Tanaka K,Watanabe T,Minamino T

更新日期：2015-12-01 00:00:00

abstract：:The aim of this study is to investigate the cardioprotective effects of morroniside in rats following acute myocardial infarction. An acute myocardial infarction (AMI) was induced by ligating the anterior descending coronary artery (LAD) [1]. Following AMI, morroniside was administered intragastrically for 24 h at dos...

journal_title：Inflammation

authors： Yu B,Wang W

更新日期：2018-03-01 00:00:00

abstract：:Lipopolysaccharide (LPS) is demonstrated to cause "two-hit" injury to liver. Proprotein convertase subtilisin/kexin type 9 (PCSK9) plays an important role in LPS clearance. Hepatocyte nuclear factor-1 alpha (HNF-1α) and sterol regulatory element-binding protein 2 (SREBP2) were reported to be responsible for PCSK9 gene...

journal_title：Inflammation

authors： Zou Y,Li S,Xu B,Guo H,Zhang S,Cai Y

更新日期：2020-02-01 00:00:00

abstract：:Previous reports showed that Maresin 1 (MaR1) possessed organ protection effects and could attenuate acute lung injury. Here, we aim to figure out whether MaR1 can maintain the permeability of lung epithelial cells by regulating the expression of tight junction protein during lung injury. Monolayer of murine lung epit...

journal_title：Inflammation

authors： Chen L,Liu H,Wang Y,Xia H,Gong J,Li B,Yao S,Shang Y

更新日期：2016-12-01 00:00:00

abstract：:Cardiovascular diseases, including acute coronary syndrome (ACS), are the leading cause of death among humans. Adhesion proteins, owing to their involvement in the initiation and progression of atherosclerotic lesions, contribute to the progression of coronary disease and ACS occurrence. Considering ambiguosity of res...

journal_title：Inflammation

authors： Dabek J,Ligus J,Szota J

更新日期：2010-12-01 00:00:00

abstract：:In this study, the effects of tyrosol were investigated in DSS-induced experimental ulcerative colitis model. For this purpose, rats were divided into five groups of seven rats in each: control group, colitis group (DSS-4%), tyrosol group (tyrosol 20 mg/kg), sulfasalazine (sulfasalazine+DSS 100 mg/kg), and treatment g...

journal_title：Inflammation

authors： Güvenç M,Cellat M,Özkan H,Tekeli İO,Uyar A,Gökçek İ,İşler CT,Yakan A

更新日期：2019-10-01 00:00:00