Protamine sulfate-induced enzyme secretion from rabbit neutrophils.

abstract：:Nitric Oxide (NO) is a reactive metabolite produced by stimulated macrophages, and it has been demonstrated to exert cytotoxic actions on a number of microbes, parasites, and tumor cells. In addition, NO has been reported to have an autotoxic effect on murine macrophages, its site of synthesis. We have investigated th...

journal_title：Inflammation

authors： Bochsler PN,Mason GL,Olchowy TW,Yang Z

更新日期：1996-04-01 00:00:00

abstract：:Previous data that alimentation with fish oil rich in eicosapentaenoic acid (EPA; 20:n-3) or vegetable oil rich in gamma-linolenic acid (GLA; 18:3n-6) can reduce symptoms of inflammatory skin disorders lead us to determine the effects of dietary supplements of oils rich in EPA or GLA on guinea pig (GP) neutrophil (PMN...

journal_title：Inflammation

authors： Fletcher MP,Ziboh VA

更新日期：1990-10-01 00:00:00

abstract：:The effects of an intravenous injection (i.v.) of Sephadex beads (20 mg kg(-1)) were examined on bronchial responsiveness to ACh (1-200 microg kg(-1) i.v.) as well as on cell accumulation in guinea-pig lung. Bronchial hyperreactivity to ACh, measured as increase in pulmonary insufflation pressure (PIP), was observed 3...

journal_title：Inflammation

authors： Conroy DM,Sirois P

更新日期：1999-10-01 00:00:00

abstract：:A variety of steroidal and nonsteroidal antiinflammatory agents (NSAs) were compared for their effectiveness against a developing acute inflammatory reaction. Only BW 755C [3-amino-1-(m-trifluoromethyl)-phenyl-2-pyrazole] was immediately effective when administered 2 h after carrageenin, as the 3-h swelling was signif...

journal_title：Inflammation

authors： Holsapple MP,Yim GK

更新日期：1984-09-01 00:00:00

abstract：:DBA/1LacJ mice were immunized with type II collagen and boosted with bacterial lipopolysaccharide (LPS) 17 days later to induce accelerated arthritis. Clinical signs of inflammation were observed as early as Day 20. Matrix metalloproteinases MMP-2, -3, -9, and -13, but not MMP-12, mRNA levels were increased on Day 24....

journal_title：Inflammation

authors： Raychaudhuri A,Chou M,Weetall M,Jeng AY

更新日期：2003-04-01 00:00:00

abstract：:Enzyme-inducing drugs such as phenobarbital (PB) increase serum concentrations of an acute-phase protein, alpha 1-acid glycoprotein (AGP), in man, dogs, and rats via an unknown mechanism. We studied the effects of PB on components of an acute inflammatory reaction in rats in order to determine if PB acts only on this ...

journal_title：Inflammation

authors： Levy FE,Chauvelot-Moachon L,Florentin I,Forest M,Poüs C,Fournier C,Giroud JP

更新日期：1991-12-01 00:00:00

abstract：:Diabetic retinopathy (DR) is a serious-threatening complication of diabetes and urgently needed to be treated. Evidence has accumulated indicating that microglia inflammation within the retina plays a critical role in DR. Microglial matrix metalloproteinase 9 (MMP-9) has an important role in the destruction of the int...

journal_title：Inflammation

authors： Zhu SH,Liu BQ,Hao MJ,Fan YX,Qian C,Teng P,Zhou XW,Hu L,Liu WT,Yuan ZL,Li QP

更新日期：2017-10-01 00:00:00

abstract：:Interleukin-10 (IL-10) is a pleiotropic cytokine and plays an important role in the pathogenesis of systemic lupus erythematosus (SLE). Unlike IL-10 protein, few studies have focused on the potential association between IL-10 receptor (IL-10R) and SLE. The purpose of this study was to examine the association of a sing...

journal_title：Inflammation

authors： Peng H,Liu CY,Zhou M,Wen PF,Zhang M,Qiu LJ,Ni J,Liang Y,Pan HF,Ye DQ

更新日期：2013-12-01 00:00:00

abstract：:Factors affecting the retinoic acid modulated expression of mucin mRNA in rat tracheal cultures were studied. Actinomycin D had no effect on mucin mRNA in cultures grown with retinoic acid (RA+). The usual precipitous drop in mucin mRNA in cultures lacking retinoic acid (RA-) was prevented by actinomycin D. Cyclohexim...

journal_title：Inflammation

authors： Bhattacharyya SN,Ashbaugh P,Kaufman B,Manna B

更新日期：1994-12-01 00:00:00

abstract：:Recombinant human tumor necrosis factor-alpha (rTNF) stimulated increased generation of superoxide anion (O2-) by human neutrophils in a concentration-dependent fashion. Preincubation of human neutrophils with rTNF (2.2-2200 units/ml) for 10 min enhanced the subsequent generation of O2- in response to C5a and f-Met-Le...

journal_title：Inflammation

authors： Bajaj MS,Kew RR,Webster RO,Hyers TM

更新日期：1992-06-01 00:00:00

abstract：:Muscle strength is of importance for postsurgical rehabilitation. Myostatin is a growth factor that regulates the size of muscles and could thus influence muscle mass and function in the postsurgical period. The aim of the present study was to study the changes in myostatin levels during the postsurgical inflammatory ...

journal_title：Inflammation

authors： Åkerfeldt T,Helmersson-Karlqvist J,Gunningberg L,Swenne CL,Larsson A

更新日期：2015-08-01 00:00:00

abstract：:Most cases of posttraumatic ankle osteoarthritis (PTAOA) represent a sequela of ankle fractures. The cytoplasmic polyadenylation element-binding protein 1 (CPEB1) is an RNA binding protein that controls protein expression. Here, we report the previously unappreciated association of CPEB1 with PTAOA. We found that CPEB...

journal_title：Inflammation

authors： Li L,Lan J,Ye Y,Yang B,Yang X,Cai Z

更新日期：2019-04-01 00:00:00

abstract：:The aim of this study is to investigate the cardioprotective effects of morroniside in rats following acute myocardial infarction. An acute myocardial infarction (AMI) was induced by ligating the anterior descending coronary artery (LAD) [1]. Following AMI, morroniside was administered intragastrically for 24 h at dos...

journal_title：Inflammation

authors： Yu B,Wang W

更新日期：2018-03-01 00:00:00

abstract：:Macrophage polarization is a dynamic and integral process of tissue inflammation and remodeling. Here we demonstrate an important role of Aurora kinase A in the regulation of inflammatory M1 macrophage polarization. We found that there was an elevated expression of Aurora-A in M1 macrophages and inhibition of Aurora-A...

journal_title：Inflammation

authors： Ding L,Gu H,Gao X,Xiong S,Zheng B

更新日期：2015-04-01 00:00:00

abstract：:The exact etiology and pathogenesis of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) are still unknown, as a result, available therapeutic options for patients are far from satisfactory. Therefore, there is a need to develop a valid therapeutic approach that can ameliorate the manifestations of CP/CPPS. F...

journal_title：Inflammation

authors： Cheng Y,Cao Y,Ihsan AU,Khan FU,Li X,Xie D,Cui X,Wang W,Liu Z,Li C,Ahmad KA,Sembatya KR,Mikrani R,Zhou X

更新日期：2019-06-01 00:00:00

abstract：:Neurodegenerative diseases such as Alzheimer, Parkinson, amyotrophic lateral sclerosis, and Huntington are incurable and debilitating conditions that result in progressive death of the neurons. The definite diagnosis of a neurodegenerative disorder is disadvantaged by the difficulty in obtaining biopsies and thereby t...

journal_title：Inflammation

authors： Nuzzo D,Picone P,Caruana L,Vasto S,Barera A,Caruso C,Di Carlo M

更新日期：2014-06-01 00:00:00

abstract：:Sepsis, a clinical syndrome occurring in patients following infection or injury, is a leading cause of morbidity and mortality worldwide. CD86 (B7-2) is a costimulatory molecule on antigen-presenting cells and plays critical roles in immune responses. In the current study, we investigated the association of two CD86 p...

journal_title：Inflammation

authors： Song H,Tang L,Xu M,Li H,Xu S,Li G,Bao X,Sun B,Cheng T,Yang Q,Bai J

更新日期：2015-04-01 00:00:00

abstract：:In the present study, we investigated the anti-inflammatory effect of roburic acid on production of nitric oxide (NO) and interlukin-6 (IL-6) in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophage cells. We found that roburic acid reduced production of NO and IL-6, and the expression of inducible nitric oxide synt...

journal_title：Inflammation

authors： Chen Y,Ji N,Pan S,Zhang Z,Wang R,Qiu Y,Jin M,Kong D

更新日期：2017-12-01 00:00:00

abstract：:1,8-Cineol is a major monoterpene principally from eucalyptus essential oils and has been shown to exert anti-inflammatory, antiviral, and inhibitory of nuclear factor (NF)-kB effect. In the present study, we evaluated the effect of 1,8-cineol on mice infected with influenza A virus. We found that 1,8-cineol protects ...

journal_title：Inflammation

authors： Li Y,Lai Y,Wang Y,Liu N,Zhang F,Xu P

更新日期：2016-08-01 00:00:00

abstract：:By the use of the nuclear microprobe technique, the concentrations of zinc in isolated erythrocytes, platelets, and granulocytes were measured in patients with rheumatoid arthritis, other inflammatory arthritides, and scleroderma. Markedly reduced cellular zinc values were found compared to those measured in healthy s...

journal_title：Inflammation

authors： Svenson KL,Hällgren R,Johansson E,Lindh U

更新日期：1985-06-01 00:00:00

abstract：:Inflammatory response is required to proceed the optimal liver regeneration after liver injury. Recent reports demonstrated that inflammasomes are involved in the innate immune response. Several NOD-Like receptors (NLRs) participated in the formation of the inflammasomes. NACHT, LRR, and PYD domain-containing protein ...

journal_title：Inflammation

authors： Ando T,Ito H,Kanbe A,Hara A,Seishima M

更新日期：2017-10-01 00:00:00

abstract：:Sepsis is a major cause of morbidity and mortality in critically ill patients. MD-2 is a 25-kDa lipopolysaccharide (LPS)-binding protein that forms a heterodimer with TLR42, but its regulation in sepsis is not clear. This study aims to investigate the molecular mechanism of regulation of MD-2. Inflammation cytokines i...

journal_title：Inflammation

authors： Wang Y,Li T,Wu B,Liu H,Luo J,Feng D,Shi Y

更新日期：2014-12-01 00:00:00

abstract：:The existence of multiple-interactive roles between several signaling pathways in tumorigenesis shows the significance of pharmacological factors like heat shock protein 90 (HSP90) inhibitors which control several signaling pathways simultaneously. HSP90 as a molecular chaperone supports the active conformational stru...

journal_title：Inflammation

authors： Mohammadi A,Yaghoobi MM,Gholamhoseinian Najar A,Kalantari-Khandani B,Sharifi H,Saravani M

更新日期：2016-06-01 00:00:00

abstract：:Lipids from the sputum of patients with asthma and with cystic fibrosis were isolated and characterized. In both cases, lipids constituted approximately 30% of the dry material. Phosphatidlycholine was the most abundant lipid, Significant amounts of phosphatidylethanolamine and phosphatidylglycerol were present. Hexos...

journal_title：Inflammation

authors： Sahu S,Lynn WS

更新日期：1978-03-01 00:00:00

abstract：:A new in vivo method for measuring leukocyte migration in man involves the insertion of "platelets" prepared from membrane filters into the lower conjunctival sac. The "platelets" contain casein and are coated unilaterally with a foil, permitting the casein to diffuse in one direction only. A chemotactic gradient is t...

journal_title：Inflammation

authors： Egger G

更新日期：1980-06-01 00:00:00

abstract：:Endoplasmic reticulum stress (ERS) plays an important role in cerebral ischemia-reperfusion injury (CIRI) by regulating apoptosis. Although the role of long non-coding RNA (LncRNA) KCNQ1OT1 in CIRI has been reported, the specific mechanism is still unclear. In this paper, the regulation of ERS by LncRNA KCNQ1OT1 in CI...

journal_title：Inflammation

authors： Li Y,Yi M,Wang D,Zhang Q,Yang L,Yang C

更新日期：2020-12-01 00:00:00

abstract：:The possibility of inflammation and neutrophil activation in response to indoor air pollution (IAP) from biomass fuel use has been investigated. For this, 142 premenopausal, never-smoking women (median age, 34 years) who cook exclusively with biomass (wood, dung, crop wastes) and 126 age-matched control women who cook...

journal_title：Inflammation

authors： Banerjee A,Mondal NK,Das D,Ray MR

更新日期：2012-04-01 00:00:00

abstract：:Baicalin, a flavonoid monomer derived from Scutellaria baicalensis called Huangqin in mandarin, is the main active ingredient contributing to S. baicalensis' efficacy. It is known in China that baicalin has potential therapeutic effects on inflammatory diseases. However, its anti-inflammatory mechanism has still not b...

journal_title：Inflammation

authors： Dong SJ,Zhong YQ,Lu WT,Li GH,Jiang HL,Mao B

更新日期：2015-08-01 00:00:00

abstract：:Lipopolysaccharide (LPS) increases serum TNF-alpha levels due to TNF-alpha secretion by macrophages. The serum TNF-alpha response to LPS was augmented 10x when FcgammaR ligation was induced by the intravenous injection of Gig-coated erythrocytes (IgG) prior to the administration of LPS. The macrophage population respo...

journal_title：Inflammation

authors： Loegering DJ,Lennartz MR

更新日期：2002-12-01 00:00:00

abstract：:We have previously reported the antifibrotic effects of pirfenidone (PD) in the bleomycin (BL)-hamster model of lung fibrosis. Since the development of fibrosis is generally preceded by acute lung inflammation, the present study was conducted to find out if dietary intake of PD (0.5%) has any effects on BL-induced lun...

journal_title：Inflammation

authors： Iyer SN,Hyde DM,Giri SN

更新日期：2000-10-01 00:00:00