Skull base chondrosarcoma: evidence-based treatment paradigms.

Abstract:

:Chondrosarcomas are indolent but invasive chondroid malignancies that can form in the skull base. Standard management of chondrosarcoma involves surgical resection and adjuvant radiation therapy. This review evaluates evidence from the literature to assess the importance of the surgical approach and extent of resection on outcomes for patients with skull base chondrosarcoma. Also evaluated is the ability of the multiple modalities of radiation therapy, such as conventional fractionated radiotherapy, proton beam, and stereotactic radiosurgery, to control tumor growth. Finally, emerging therapies for the treatment of skull-base chondrosarcoma are discussed.

journal_name

Neurosurg Clin N Am

authors

Bloch O,Parsa AT

doi

10.1016/j.nec.2012.08.002

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

89-96

issue

1

eissn

1042-3680

issn

1558-1349

pii

S1042-3680(12)00090-3

journal_volume

24

pub_type

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