Abstract:
:Intrathecal drug delivery represents an advanced modality for refractory chronic pain patients as well as intractable spasticity. This article reviews the advantages and indications for intrathecal therapy, as well as recommendations for proper patient selection using a multidisciplinary team to provide a global assessment of the impact of chronic pain on the patient's well-being. The goals and expectations of trialing are discussed alongside advantages and disadvantages of several trialing techniques. A discussion of outcomes is presented for patients with chronic pain due to both malignant and nonmalignant causes.
journal_name
Neurosurg Clin N Amjournal_title
Neurosurgery clinics of North Americaauthors
Bolash R,Mekhail Ndoi
10.1016/j.nec.2014.06.006subject
Has Abstractpub_date
2014-10-01 00:00:00pages
735-42issue
4eissn
1042-3680issn
1558-1349pii
S1042-3680(14)00062-Xjournal_volume
25pub_type
杂志文章,评审abstract::Electrical stimulation of the spinal cord for the relief of pain was first reported in 1967. Since that time, there have been marked improvements in patient selection criteria, hardware, technology, and methods for implantation, which have resulted in substantial improvement in the overall results achieved with spinal...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1995-01-01 00:00:00
abstract::Shunt failure remains a disheartening complication of shunt surgery. The number of adjustable factors in attempting to reduce the rate is small. The clinical presentation and timing of shunt malfunction are well documented. Although the shunt design trials have been negative to date, valves have important effects that...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:2001-10-01 00:00:00
abstract::We provide a history and overview of the network approach to epilepsy surgery. Models of the epileptogenic zone (EZ) have evolved considerably over the years with more recent models accounting for the connectivity and network properties of epileptic foci. Next, we describe several examples of network phenotypes of foc...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nec.2020.03.011
更新日期:2020-07-01 00:00:00
abstract::Stereotactic radiosurgery is used for many indications. In functional neurosurgery, it is used to modulate the function of axons, neurons, and related brain circuits. In this article, indications, current techniques, and outcomes are discussed. ...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nec.2013.06.001
更新日期:2013-10-01 00:00:00
abstract::There seems to be no doubt that periarterial clot causes vasospasm and that vasospasm is a significant cause of delayed ischemic neurologic deficits and infarcts. It is to be hoped that a way can be found to remove such clots effectively and rapidly before they do their deadly damage. ...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1990-04-01 00:00:00
abstract::Positron emission tomography (PET) scanning provides a sensitive means of detecting and characterizing regional changes in brain metabolism and receptor binding in movement disorders. PET allows the quantitative examination of regional cerebral blood flow, regional glucose and oxygen metabolism, and brain pharmacology...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1998-04-01 00:00:00
abstract::Flatback syndrome is characterized by loss of normal lumbar lordosis, resulting in forward tilt of the trunk, inability to stand erect, back pain, and thigh pain from chronic hip flexion and knee bending. The usual etiology is iatrogenic, through previous fusions or with extension instrumentation. Surgical treatments ...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nec.2007.01.007
更新日期:2007-04-01 00:00:00
abstract::This article describes the presentation of tussive headaches in the adult population. Posterior headaches can also occur in patients with basilar invagination, and they may require occipital cervical fusion. Lower cranial nerve dysfunction is another common presenting symptom in adult Chiari patients. Almost 25% of sy...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nec.2015.07.001
更新日期:2015-10-01 00:00:00
abstract::The indications for the surgical management of supratentorial cavernous malformations are outlined and the results following operation are presented in this article. Surgery is indicated for most patients who present with seizures, neurologic deficit, or headache. The surgical approaches to lesions in the cerebrum are...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1999-07-01 00:00:00
abstract::Chronic deep brain stimulation (DBS) is a promising technique for the treatment of movement disorders. Thalamic stimulation is now an established surgical procedure for parkinsonian and essential tremor. Pallidal and subthalamic stimulation are under active investigation as treatments for Parkinson's disease. Although...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1998-04-01 00:00:00
abstract::Advances in imaging have made possible confident diagnosis of infiltrative pontine gliomas without biopsy. When the diagnosis is in doubt, stereotactic biopsy is the procedure of choice. Surgical intervention is restricted to tumors with a dorsally exophytic component and other rare circumstances. ...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1993-07-01 00:00:00
abstract::Intracerebral hemorrhage is bleeding into the brain parenchyma with possible extension into the ventricles and subarachnoid space. Each year, approximately 37,000 to 52,400 people suffer from intraparenchymal hemorrhage (IPH) in the United States. This rate is expected to rise dramatically in the next few decades as a...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s1042-3680(02)00010-4
更新日期:2002-07-01 00:00:00
abstract::The basic premises of thermographic analysis for low back problems are that variations in skin temperature signify certain and specific underlying disease processes. The newer technologic advances for monitoring skin temperature raise the questions of whether thermography is an adequate substitute for invasive diagnos...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1991-10-01 00:00:00
abstract::The refinement in the intravascular techniques has revolved upon the development of new material and a better understanding of neurophysiology. Access has become less of a limitation, and more emphasis is now placed on getting the job done: closing a fistula, obliterating a malformation, or filling an aneurysm. Emboli...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1994-07-01 00:00:00
abstract::Although timing for surgical intervention after spinal cord injury remains controversial, there is accumulating evidence suggesting that early surgery may improve neurologic outcomes, particularly with incomplete spinal cord injury, and may reduce non-neurologic complications and health care resource utilization. More...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nec.2016.08.005
更新日期:2017-01-01 00:00:00
abstract::Glioblastoma multiforme is a malignant, relentless brain cancer with no known cure, and standard therapies leave significant room for the development of better, more effective treatments. Immunotherapy is a promising approach to the treatment of solid tumors that directs the patient's own immune system to destroy tumo...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nec.2009.09.001
更新日期:2010-01-01 00:00:00
abstract::There is no clear plane between the dura and arachnoid in situ. Instead of the virtual subdural space, there is a dura-arachnoid interface layer, which is structurally the weakest throughout the meninges. An extravasation of blood within the dural border layer splits it, leaving a few tiers of dural border cells over ...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:2000-07-01 00:00:00
abstract::Medial temporal lobe epilepsy associated with mesial temporal sclerosis (MTS) is perhaps the most well-defined epilepsy syndrome that is responsive to structural interventions such as surgery. Several minimally invasive techniques have arisen that provide additional options for the treatment of MTS while potentially a...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nec.2015.08.011
更新日期:2016-01-01 00:00:00
abstract::In this review, we focus on novel surgical techniques and spinal arthroplasty systems inactive development. First, we discuss systems that allow for minimally invasive approaches to the lumbar disc space: (1) lateral approaches, (2) posterior approaches,and (3) oblique approaches. These techniques offer the potential ...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nec.2005.08.001
更新日期:2005-10-01 00:00:00
abstract::The recognition of a number of uncommon tumors of the skull base is now relatively simple because of three-dimensional computed tomography and magnetic resonance imaging with enhancement. The radiographic classification of these tumors is reviewed, and their treatment is discussed. Although the basic approach to these...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1990-01-01 00:00:00
abstract::Medical management of the post-epilepsy surgery patient depends on careful preoperative consideration of that patient's medical, social, cognitive, and emotional status. Outcome expectations should be realistic. Families should be warned that existing cognitive and psychobehavioral problems may not be following surger...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1995-07-01 00:00:00
abstract::The technique of stereotactic proton radiosurgery is discussed in depth in this article. The physics of the proton beam in radiosurgery is explained, and the different factors of beam delivery are examined. These key factors (correspondence to shape, accuracy of delineation of volume, correspondence to volume, and acc...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章
doi:
更新日期:1999-04-01 00:00:00
abstract::The middle fossa approach is useful for the removal of small acoustic tumors when hearing preservation is possible. This approach provides complete exposure of the contents of the internal auditory canal and positive facial nerve identification. Because access to the posterior fossa is limited, the middle fossa approa...
journal_title:Neurosurgery clinics of North America
pub_type: 传,古典文章,历史文章,杂志文章
doi:10.1016/j.nec.2008.02.009
更新日期:2008-04-01 00:00:00
abstract::Somatosensory evoked potentials (SSEP) are a valuable clinical tool in the operating theater. Multichannel SSEP monitoring is an objective measure of CBF and cerebral function. The monitoring of the SSEP during carotid surgery is a simple and reliable method of determining the effect of carotid clamping on CBF and the...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1996-10-01 00:00:00
abstract::The use of ionizing radiation in the treatment of benign intracranial tumors may involve one of several types of ionizing radiation given as single-fraction radiosurgery or fractionated radiotherapy. An understanding of the biophysical and radiobiologic principles involved in these treatments is essential to the desig...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章
doi:10.1016/j.nec.2006.02.003
更新日期:2006-04-01 00:00:00
abstract::Temporal lobe epilepsy is not a single clinicopathologic entity but a group of syndromes requiring different surgical solutions. Anatomic resections planned for the treatment of these syndromes are aimed at pathologic substrates minimizing ablation of normal tissue. Most of these procedures involve mesial and lateral ...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1993-04-01 00:00:00
abstract::Degenerative cervical myelopathy (DCM) is the leading cause of spinal cord impairment worldwide. Surgical intervention has been demonstrated to be effective and is becoming standard of care. Spine surgery, however, is costly and value needs to be demonstrated. This review serves to summarize the key health economic co...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nec.2017.09.013
更新日期:2018-01-01 00:00:00
abstract::Chondrosarcomas are indolent but invasive chondroid malignancies that can form in the skull base. Standard management of chondrosarcoma involves surgical resection and adjuvant radiation therapy. This review evaluates evidence from the literature to assess the importance of the surgical approach and extent of resectio...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nec.2012.08.002
更新日期:2013-01-01 00:00:00
abstract::Inadequate healing is an important mechanism for aneurysm development and recanalization after embolization. Matrix coils have been shown by experimental studies to enhance vascular repair and fibrosis, thus reducing the risk of recanalization. The clinical application of Matrix coils represents the transition from pu...
journal_title:Neurosurgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nec.2005.03.001
更新日期:2005-07-01 00:00:00
abstract::For nearly a century, neurosurgeons have been involved in the use of therapeutic radiation. Long before there was a separate discipline of radiology or radiation therapy, pioneers such as Cushing and Frasier explored the effects of X-rays and radium on patients with brain tumors and arteriovenous malformations. This i...
journal_title:Neurosurgery clinics of North America
pub_type: 历史文章,杂志文章
doi:
更新日期:2001-01-01 00:00:00