Deep brain stimulation for movement disorders.

Abstract:

:Chronic deep brain stimulation (DBS) is a promising technique for the treatment of movement disorders. Thalamic stimulation is now an established surgical procedure for parkinsonian and essential tremor. Pallidal and subthalamic stimulation are under active investigation as treatments for Parkinson's disease. Although high-frequency DBS at these sites has similar behavioral effects as lesioning, the physiologic mechanisms underlying the beneficial effect of DBS is not well understood and may be extremely complex. DBS offers a potential advantage over ablative therapy because stimulation-induced complications are reversible, and the stimulation parameters are adjustable to minimize complications and maximize therapeutic effects. With this added safety, bilateral stimulation or use of a stimulator following a prior procedure may be preferable to bilateral ablative procedures.

journal_name

Neurosurg Clin N Am

authors

Starr PA,Vitek JL,Bakay RA

subject

Has Abstract

pub_date

1998-04-01 00:00:00

pages

381-402

issue

2

eissn

1042-3680

issn

1558-1349

journal_volume

9

pub_type

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