Abstract：
:Pineoblastomas (PBs) represent the most aggressive of the pineal parenchymal tumors. Routine treatment consists of operative management of obstructive hydrocephalus and cerebrospinal fluid studies followed by maximal resection and adjuvant chemotherapy/radiotherapy, resulting in a median survival of 20 months. Important prognostic factors for survival of patients with PB include extent of resection, age at presentation, disseminated disease, and craniospinal radiotherapy. Novel strategies being evaluated for the treatment of PB include high-dose chemotherapy with autologous stem cell therapy, stereotactic radiosurgery, and histone deacetylase inhibitors.
journal_name
Neurosurg Clin N Amjournal_title
Neurosurgery clinics of North Americaauthors
Tate MC,Rutkowski MJ,Parsa ATdoi
10.1016/j.nec.2011.05.001subject
Has Abstractpub_date
2011-07-01 00:00:00pages
409-12, ixissue
3eissn
1042-3680issn
1558-1349pii
S1042-3680(11)00046-5journal_volume
22pub_type
杂志文章,评审abstract：:Deep brain stimulation (DBS) plays an important role in the treatment of chronic pain when other less invasive treatment modalities have been exhausted. DBS is an apparently safe and effective treatment option for a select group of patients. Further research into the mechanisms of pain relief by DBS and careful prospe...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,meta分析,评审
doi：10.1016/s1042-3680(03)00036-6
更新日期：2003-07-01 00:00:00
abstract：:Cerebral venous sinus (sinovenous) thrombosis (CSVT) in childhood is a rare, but underrecognized, disorder, typically of multifactorial etiology, with neurologic sequelae apparent in up to 40% of survivors and mortality approaching 10%. There is an expanding spectrum of perinatal brain injury associated with neonatal ...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2010.03.006
更新日期：2010-07-01 00:00:00
abstract：:Management of anticoagulation and antiplatelet medications after neurosurgery can be complex, especially given that these patients have multiple medical comorbidities. In turn, neurosurgical patients are at high risk for the development of venous thromboembolism after surgery, so neurosurgeons must consider the use of...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2018.06.008
更新日期：2018-10-01 00:00:00
abstract：:The combination of separation surgery and stereotactic body radiotherapy optimizes the treatment of metastatic spine tumors. The integration of SBRT into treatment paradigms produces superb local control rates and consequently has diminished the role of surgery from principle treatment to one of adjuvant therapy. Unde...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2019.11.001
更新日期：2020-04-01 00:00:00
abstract：:With careful patient selection, timely neuroendovascular therapy can improve the clinical outcome of patients suffering from cerebrovascular ischemic disease. The current indications, techniques, recent experiences, limitations, and future directions of balloon angioplasty and local intra-arterial/intravenous thrombol...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：2000-01-01 00:00:00
abstract：:There is no clear plane between the dura and arachnoid in situ. Instead of the virtual subdural space, there is a dura-arachnoid interface layer, which is structurally the weakest throughout the meninges. An extravasation of blood within the dural border layer splits it, leaving a few tiers of dural border cells over ...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：2000-07-01 00:00:00
abstract：:Soft cervical disc herniations can be treated by minimally invasive procedures with excellent results. Chemonucleolysis with chymopapain is one alternative to surgery that is shown to be innocuous within a strict technical framework. MR imaging allows an accurate diagnosis of the cause of cervical root compression, th...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:The pelvic incidence defines the amount of lordosis required in the lumbar spine, and a lumbar lordosis within 11° of the pelvic incidence defines alignment of the lumbo-pelvic region. Pelvic tilt is a compensatory mechanism that allows patients to achieve sagittal balance in the setting of decreased lumbar lordosis w...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2018.03.003
更新日期：2018-07-01 00:00:00
abstract：:Herniated lumbar discs are rare in teh pediatric population. The clinical features,diagnostic modalities, and treatment are discussed in detail.The overall surgical results have been excellent in more than 90% of patients in most series. The differences between children and adults with herniated lumbar discs are empha...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1993-01-01 00:00:00
abstract：:Functional brain imaging studies of memory and attention with positron emission tomography and functional magnetic resonance imaging demonstrate involvement of specific regions of the normal human brain. Possible anatomical substrates for different types of memory have been identified. Different aspects of attention m...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1997-07-01 00:00:00
abstract：:This review provides historical and recent perspectives related to passive immunotherapy for high-grade gliomas. The authors discuss approaches that use lymphokine-activated killer cells, cytotoxic T lymphocytes, and monoclonal antibodies. ...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2012.04.008
更新日期：2012-07-01 00:00:00
abstract：:Inadequate healing is an important mechanism for aneurysm development and recanalization after embolization. Matrix coils have been shown by experimental studies to enhance vascular repair and fibrosis, thus reducing the risk of recanalization. The clinical application of Matrix coils represents the transition from pu...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2005.03.001
更新日期：2005-07-01 00:00:00
abstract：:Medical errors are common and dangerous, estimated to cause over 400,000 deaths per year in the United States alone. The field of neurosurgery is not immune to these errors, and many studies have begun analyzing the frequency and types of errors that neurosurgical patients experience, along with their effects and caus...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2014.11.011
更新日期：2015-04-01 00:00:00
abstract：:Carotid occlusive disease remains an important cause of ischemic stroke. The results of large, randomized, clinical trials have established the benefit of surgical revascularization in patients with symptomatic or asymptomatic carotid stenosis. The introduction of balloon angioplasty and stenting of the extracranial c...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章
doi：10.1016/j.nec.2008.07.011
更新日期：2008-07-01 00:00:00
abstract：:Spinal dural arteriovenous fistulas (AVFs) are the most common spinal vascular malformation. The spinal dural AVF is a disease of adults, primarily men, that is a cause of subacute progressive lower extremity myelopathy. The challenge for the optimum management of these patients is in making an accurate, early diagnos...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1999-01-01 00:00:00
abstract：:Tissue diagnosis is necessary for optimal treatment of pineal region tumors in children. Preoperative staging should include craniospinal MR imaging with and without gadolinium DTPA enhancement, CSF sampling for cytology, and measurement of biologic tumor markers in serum and CSF. Surgical approach is determined by re...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1992-10-01 00:00:00
abstract：:The intracranial electroencephalogram (iEEG) is essential in decision making for epilepsy surgery. Although localization of epileptogenic brain regions by means of iEEG has been the gold standard for surgical decision-making for more than 70 years, established guidelines for what constitutes genuine iEEG epileptic act...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2020.03.007
更新日期：2020-07-01 00:00:00
abstract：:This article provides basic pharmacologic and behavioral principles and facts to simplify drug therapy for low back pain. It outlines basic protocols for symptom control while definitive treatments are beginning or healing occurs. ...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1991-10-01 00:00:00
abstract：:In this review, we focus on novel surgical techniques and spinal arthroplasty systems inactive development. First, we discuss systems that allow for minimally invasive approaches to the lumbar disc space: (1) lateral approaches, (2) posterior approaches,and (3) oblique approaches. These techniques offer the potential ...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2005.08.001
更新日期：2005-10-01 00:00:00
abstract：:Intrathecal drug delivery has been well established an effective and safe method for the treatment of pain, including palliative cancer-related and chronic nonmalignant pain. In this article, we discuss the role of intrathecal pain therapy in the management of chronic, refractory nonmalignant pain. Common indications,...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2018.12.010
更新日期：2019-04-01 00:00:00
abstract：:The primary goal of any surgical approach is to adequately visualize and treat the pathologic condition with minimal disruption to adjacent normal anatomy. The work of several researchers has revealed the promise of minimally invasive endonasal neurosurgery and paved the way for broader applications of the technology....
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2010.07.010
更新日期：2010-10-01 00:00:00
abstract：:Malignant large artery stroke is associated with high mortality of 70% to 80% with best medical management. Decompressive craniectomy (DC) is a highly effective tool in reducing mortality. Convincing evidence has accumulated from several randomized trials, in addition to multiple retrospective studies, that demonstrat...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2017.02.010
更新日期：2017-07-01 00:00:00
abstract：:Surgical management of giant cerebral aneurysms remains a major technical challenge for modern neurosurgeons. Endovascular approaches for giant aneurysms does not provide an acceptable alternative to direct surgical approaches. The use of deep hypothermic circulatory arrest as an adjunct during clipping of complex gia...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1998-10-01 00:00:00
abstract：:Shared decision making is a collaborative decision-making process between health care providers and patients or their surrogates, taking into account the best scientific evidence available while considering the patient's values, goals, and preferences. Decision aids are tools enabling SDM. This article discusses share...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2017.11.009
更新日期：2018-04-01 00:00:00
abstract：:There are two hypotheses on how chronic subdural hematoma causes hemiparesis and other focal neurologic symptoms without, in most cases, leaving permanent neurologic deficits. One hypothesis is that the reduced regional cerebral blood flow (rCBF) caused by either compression or distortion of the local or remote brain ...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：2000-07-01 00:00:00
abstract：:The role of intracranial pressure monitoring as an adjunct to the clinical examination, CT scanning, and other diagnostic modalities has become increasingly recognized. This article presents a brief overview of the present status of this technique and touches on prospects for further developments. ...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1991-04-01 00:00:00
abstract：:Electrical stimulation of the spinal cord for the relief of pain was first reported in 1967. Since that time, there have been marked improvements in patient selection criteria, hardware, technology, and methods for implantation, which have resulted in substantial improvement in the overall results achieved with spinal...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1995-01-01 00:00:00
abstract：:Somatosensory evoked potentials (SSEP) are a valuable clinical tool in the operating theater. Multichannel SSEP monitoring is an objective measure of CBF and cerebral function. The monitoring of the SSEP during carotid surgery is a simple and reliable method of determining the effect of carotid clamping on CBF and the...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1996-10-01 00:00:00
abstract：:Central neurocytoma (CN) is a well-differentiated tumor of neural cells occurring within the ventricles. It is composed of monomorphic cells with round, regular nuclei within clear cytoplasm and must be distinguished from other clear cell tumors. Immunohistochemical markers of CN that aid in diagnosis include synaptop...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2014.09.001
更新日期：2015-01-01 00:00:00
abstract：:The major unifying concept of the effect of trauma on the central nervous system is the application of force to the brain. The mode of delivery of energy and its dissipation result in the varying pathologic manifestations of hemorrhage, contusions, or tears. Topics discussed in this article include inner cerebral trau...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1994-01-01 00:00:00
