Abstract：
:The combination of separation surgery and stereotactic body radiotherapy optimizes the treatment of metastatic spine tumors. The integration of SBRT into treatment paradigms produces superb local control rates and consequently has diminished the role of surgery from principle treatment to one of adjuvant therapy. Under this paradigm, hybrid therapy for the treatment of metastatic spine tumors employs separation surgery to decompress the spinal cord and stabilize the spine while creating a safe target for ablative SBRT. Hybrid therapy is well tolerated, allows an early return to systemic therapy, and provides durable, local tumor control compared with more aggressive traditional approaches.
journal_name
Neurosurg Clin N Amjournal_title
Neurosurgery clinics of North Americaauthors
Rothrock R,Pennington Z,Ehresman J,Bilsky MH,Barzilai O,Szerlip NJ,Sciubba DMdoi
10.1016/j.nec.2019.11.001subject
Has Abstractpub_date
2020-04-01 00:00:00pages
191-200issue
2eissn
1042-3680issn
1558-1349pii
S1042-3680(19)30095-6journal_volume
31pub_type
杂志文章,评审abstract：:Chondrosarcomas are indolent but invasive chondroid malignancies that can form in the skull base. Standard management of chondrosarcoma involves surgical resection and adjuvant radiation therapy. This review evaluates evidence from the literature to assess the importance of the surgical approach and extent of resectio...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2012.08.002
更新日期：2013-01-01 00:00:00
abstract：:Somatosensory evoked potentials (SSEP) are a valuable clinical tool in the operating theater. Multichannel SSEP monitoring is an objective measure of CBF and cerebral function. The monitoring of the SSEP during carotid surgery is a simple and reliable method of determining the effect of carotid clamping on CBF and the...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1996-10-01 00:00:00
abstract：:Temporal lobe epilepsy is not a single clinicopathologic entity but a group of syndromes requiring different surgical solutions. Anatomic resections planned for the treatment of these syndromes are aimed at pathologic substrates minimizing ablation of normal tissue. Most of these procedures involve mesial and lateral ...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1993-04-01 00:00:00
abstract：:Two-dimensional cine phase contrast (2D-cine PC) magnetic resonance (MR) imaging is an imaging technique that sensitizes MR images to velocity changes in a specific direction while cancelling signals from stationary protons and from motion in other directions. This article reviews the technique, conventions, and appli...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1993-10-01 00:00:00
abstract：:The recognition of a number of uncommon tumors of the skull base is now relatively simple because of three-dimensional computed tomography and magnetic resonance imaging with enhancement. The radiographic classification of these tumors is reviewed, and their treatment is discussed. Although the basic approach to these...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1990-01-01 00:00:00
abstract：:Inadequate healing is an important mechanism for aneurysm development and recanalization after embolization. Matrix coils have been shown by experimental studies to enhance vascular repair and fibrosis, thus reducing the risk of recanalization. The clinical application of Matrix coils represents the transition from pu...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2005.03.001
更新日期：2005-07-01 00:00:00
abstract：:The intracranial electroencephalogram (iEEG) is essential in decision making for epilepsy surgery. Although localization of epileptogenic brain regions by means of iEEG has been the gold standard for surgical decision-making for more than 70 years, established guidelines for what constitutes genuine iEEG epileptic act...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2020.03.007
更新日期：2020-07-01 00:00:00
abstract：:Proximal junctional failure (PJF) should be distinguished from proximal junctional kyphosis, which is a recurrent deformity with limited clinical impact. PJF includes mechanical failure, and is a significant complication following adult spinal deformity surgery with potential for neurologic injury and increased need f...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2013.01.001
更新日期：2013-04-01 00:00:00
abstract：:Successful surgery within the brain stem parenchyma demands precise knowledge of the surface anatomy, relationship between surface and deep structures, microscopic anatomy, and functional anatomy of the brain stem. Emphasis on correlative knowledge of these aspects of brain stem anatomy will improve the success of bra...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1993-07-01 00:00:00
abstract：:This article describes details of the application of computer modeling of cerebral blood circulation. A brief review of the different computer modeling techniques and the current models used today for predicting surgical options for bypass surgery are presented. The use of phase contrast MR for estimating intracranial...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章
doi：
更新日期：2001-07-01 00:00:00
abstract：:Primary sarcomas are rare in the spine. Common primary sarcomas include osteosarcoma, Ewing's sarcoma, chondrosarcomas, and retroperitoneal soft-tissue sarcomas. These tumors tend to occur in adolescents and young adults. Surgery remains the mainstay of treatment, although the anatomy of spine and spinal cord often li...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2007.10.001
更新日期：2008-01-01 00:00:00
abstract：:With careful patient selection, timely neuroendovascular therapy can improve the clinical outcome of patients suffering from cerebrovascular ischemic disease. The current indications, techniques, recent experiences, limitations, and future directions of balloon angioplasty and local intra-arterial/intravenous thrombol...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：2000-01-01 00:00:00
abstract：:This article reviews the role of modalities that directly monitor brain parenchyma in patients with severe traumatic brain injury. The physiology monitored involves compartmental and perfusion pressures, tissue oxygenation and metabolism, quantitative blood flow, pressure autoregulation, and electrophysiology. There a...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2016.05.010
更新日期：2016-10-01 00:00:00
abstract：:Laser interstitial thermal therapy is a minimally invasive surgical alternative to craniotomy that uses laser light through a fiber optic probe placed within a target lesion to create thermal tissue damage, resulting in cellular death. It is used in neuro-oncology to treat inaccessible lesions and obviate morbidity in...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2020.06.004
更新日期：2020-10-01 00:00:00
abstract：:Cerebral vasospasm is a cause of significant morbidity and mortality in patients with subarachnoid hemorrhage (SAH). Most cases of vasospasm can be managed medically. Medical strategies for treatment include hemodynamic augmentation to improve cerebral perfusion pressure and medical therapy to prevent or reduce cerebr...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2009.10.007
更新日期：2010-04-01 00:00:00
abstract：:Tentorial meningiomas are encountered relatively infrequently, but it is nonetheless important to be aware of their variable clinical presentations and the need for individualized preoperative assessment and surgical management. The challenges presented by these lesions are due in large part to the complexity and vari...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1994-04-01 00:00:00
abstract：:Whenever possible, maximal safe resection is the first intervention for management of glioblastoma. Resection offers tissue for diagnosis, decompression of the brain, cytoreduction, and has been associated with prolonged survival in numerous retrospective studies. In this review, we provide a critical overview of the ...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2020.08.002
更新日期：2021-01-01 00:00:00
abstract：:The modern era of minimally invasive spine surgery has its roots in percutaneous techniques developed in the mid-twentieth century. The widespread application of minimally invasive techniques seen today is predicated on technologic developments of only the past 10 years, however. This article reviews the development o...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2006.06.007
更新日期：2006-10-01 00:00:00
abstract：:Computer-assisted medical imaging technology provides useful tools for the in vivo study of congenital craniofacial deformities. Using these tools, a standardized operation for infants with nonsyndromal unicoronal synostosis has been shown to consistently normalize orbital dimensions and decrease exocranial base angul...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章
doi：
更新日期：1991-07-01 00:00:00
abstract：:The use of ionizing radiation in the treatment of benign intracranial tumors may involve one of several types of ionizing radiation given as single-fraction radiosurgery or fractionated radiotherapy. An understanding of the biophysical and radiobiologic principles involved in these treatments is essential to the desig...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章
doi：10.1016/j.nec.2006.02.003
更新日期：2006-04-01 00:00:00
abstract：:The early surgical treatment of abnormalities that are encountered in the pediatric population that affect the craniocervical junction and the upper cervical spine was by way of a posterior route. The advances in neurodiagnostic imaging and microsurgical instrumentation have been coupled with the improved understandin...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2007.04.006
更新日期：2007-10-01 00:00:00
abstract：:Soft cervical disc herniations can be treated by minimally invasive procedures with excellent results. Chemonucleolysis with chymopapain is one alternative to surgery that is shown to be innocuous within a strict technical framework. MR imaging allows an accurate diagnosis of the cause of cervical root compression, th...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:Treatment of dystonia refractory to oral medications or botulinum toxin injections includes the use of deep brain stimulation (DBS). Expectations should be established based on patient-related factors, including type of dystonia, genetic cause, target symptoms, age at the time of surgery, disease duration, or the pres...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2013.08.014
更新日期：2014-01-01 00:00:00
abstract：:In summary, over a period of approximately four decades, an important new pathologic process was identified. There is no longer any doubt that the deposition of the subarachnoid clot in the basal cisterns can, over the course of a few days, lead to a progressive, severe vasoconstriction. This, in turn, can reduce cere...
journal_title：Neurosurgery clinics of North America
pub_type： 历史文章,杂志文章
doi：
更新日期：1990-04-01 00:00:00
abstract：:Advances in imaging have made possible confident diagnosis of infiltrative pontine gliomas without biopsy. When the diagnosis is in doubt, stereotactic biopsy is the procedure of choice. Surgical intervention is restricted to tumors with a dorsally exophytic component and other rare circumstances. ...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1993-07-01 00:00:00
abstract：:During the last 10 years, gene therapy has certainly risen to the forefront of basic science and clinical medicine. Designing more efficient gene delivery systems is currently the "holy grail" of genetic therapeutics, because even the most efficient viral vectors do not transfect all cells at the treatment site, which...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：2000-10-01 00:00:00
abstract：:Intracerebral hemorrhage (ICH) is a significant cause of morbidity and mortality. With the aging population, increased use of anticoagulants, and changing racial and ethnic landscape of the United States, the incidence of ICH will increase over the next decade. Improvements in preventative strategies to treat hyperten...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2013.03.002
更新日期：2013-07-01 00:00:00
abstract：:Glioblastoma (GBM) is infiltrative neoplasm with limited treatment options and poor overall survival. Stereotactic radiosurgery (SRS) allows spatially precise and conformal delivery of high doses of radiation. Salvage SRS for locally recurrent GBM was shown to improve patient survival and have more favorable safety pr...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2020.08.007
更新日期：2021-01-01 00:00:00
abstract：:Anterior cervical discectomy and corpectomy for the treatment of cervical spondylosis,cervical disc herniation, and ossification of the posterior longitudinal ligament enjoy favorable rates of fusion and successful clinical outcomes. Although the complications from these procedures have been well described, the pathog...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.nec.2005.07.004
更新日期：2005-10-01 00:00:00
abstract：:This article is an overview of the recent advances and cosmetic implications of various aspects of craniofacial surgery from a plastic surgical viewpoint. ...
journal_title：Neurosurgery clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s1042-3680(02)00021-9
更新日期：2002-10-01 00:00:00
