The Role of Multimodal Invasive Monitoring in Acute Traumatic Brain Injury.

Abstract:

:This article reviews the role of modalities that directly monitor brain parenchyma in patients with severe traumatic brain injury. The physiology monitored involves compartmental and perfusion pressures, tissue oxygenation and metabolism, quantitative blood flow, pressure autoregulation, and electrophysiology. There are several proposed roles for this multimodality monitoring, such as to track, prevent, and treat the cascade of secondary brain injury; monitor the neurologically injured patient; integrate various data into a composite, patient-specific, and dynamic picture; apply protocolized, pathophysiology-driven intensive care; use as a prognostic marker; and understand pathophysiologic mechanisms involved in secondary brain injury to develop preventive and abortive therapies, and to inform future clinical trials.

journal_name

Neurosurg Clin N Am

authors

Lazaridis C,Robertson CS

doi

10.1016/j.nec.2016.05.010

subject

Has Abstract

pub_date

2016-10-01 00:00:00

pages

509-17

issue

4

eissn

1042-3680

issn

1558-1349

pii

S1042-3680(16)30031-6

journal_volume

27

pub_type

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