Effect of lipoxin A4 on myocardial ischemia reperfusion injury following cardiac arrest in a rabbit model.

abstract：:Exposure of human neutrophils to concanavalin A (Con A) resulted in a time- and concentration-dependent extracellular release of granule-associated lysozyme but not beta-glucuronidase or cytosolic lactate dehydrogenase. Maximum extrusion of lysozyme occurred 30 min after cell contact with Con A. The percent of total g...

journal_title：Inflammation

authors： Smith RJ,Iden SS

更新日期：1980-12-01 00:00:00

abstract：:Age-related macular degeneration (AMD) is the predominant cause of irreversible blindness in the elderly population. Despite intensive basic and clinical research, its pathogenesis remains unclear. However, evidence suggests that immunological and inflammatory factors contribute to the pathogenesis of AMD. A newly ide...

journal_title：Inflammation

authors： Liu XC,Liu XF,Jian CX,Li CJ,He SZ

更新日期：2012-04-01 00:00:00

abstract：:The release of inflammatory cytokines and chemokines and autophagy has been reported to be involved in the pathogenic mechanism of acute lung injury (ALI). Reportedly, alpha-7 nicotinic acetylcholine receptors (α7nAchR) might play a protective role in LPS-induced ALI. In the current research, we established LPS-induce...

journal_title：Inflammation

authors： Zhao X,Yu Z,Lv Z,Meng L,Xu J,Yuan S,Fu Z

更新日期：2019-12-01 00:00:00

abstract：:Baicalein shows anti-inflammatory effects in human rheumatoid arthritis fibroblast-like synoviocytes (RAFLS). Considering its anti-proliferatory effects on various cancer cells, we investigated the effects of baicalein on interleukin-1 beta (IL-1β)-induced proliferation of human RAFLS. Cell proliferation was examined ...

journal_title：Inflammation

authors： Chen S,Yang Y,Feng H,Wang H,Zhao R,Liu H

更新日期：2014-02-01 00:00:00

abstract：:Endoplasmic reticulum stress (ERS) plays an important role in cerebral ischemia-reperfusion injury (CIRI) by regulating apoptosis. Although the role of long non-coding RNA (LncRNA) KCNQ1OT1 in CIRI has been reported, the specific mechanism is still unclear. In this paper, the regulation of ERS by LncRNA KCNQ1OT1 in CI...

journal_title：Inflammation

authors： Li Y,Yi M,Wang D,Zhang Q,Yang L,Yang C

更新日期：2020-12-01 00:00:00

abstract：:Experimental studies indicate that sepsis causes remote organ injury although the molecular mechanism has not been clearly defined. In this report, the role of oxidative damage, and inflammation on lung injury, following sepsis model by cecal ligation and puncture, and the effects of quercetin, antioxidant, and anti-i...

journal_title：Inflammation

authors： Gerin F,Sener U,Erman H,Yilmaz A,Aydin B,Armutcu F,Gurel A

更新日期：2016-04-01 00:00:00

abstract：:Dysregulated release of neutrophil reactive oxygen species and proteolytic enzymes contributes to both acute and chronic inflammatory diseases. Therefore, molecular regulators of these processes are potential targets for new anti-inflammatory therapies. We have shown previously that myristoylated alanine-rich C-kinase...

journal_title：Inflammation

authors： Sheats MK,Sung EJ,Adler KB,Jones SL

更新日期：2015-01-01 00:00:00

abstract：:The anti-inflammatory activities of kakkalide, a major constituent of the flower of Pueraria thunbergiana, and irisolidone, a metabolite of kakkalide produced by intestinal microflora, against carrageenan-induced inflammation in air pouches on the backs of mice and in lipopolysaccharide (LPS)-stimulated peritoneal mac...

journal_title：Inflammation

authors： Min SW,Park YJ,Kim DH

更新日期：2011-10-01 00:00:00

abstract：:To investigate the effect of dexmedetomidine post-conditioning on the inflammatory response and autophagy effect of focal cerebral ischemia reperfusion injury in rats, and further to study its potential mechanisms. Water maze was conducted to evaluate spatial learning and memory ability of middle cerebral artery occlu...

journal_title：Inflammation

authors： Zhu Y,Li S,Liu J,Wen Q,Yu J,Yu L,Xie K

更新日期：2019-12-01 00:00:00

abstract：:During phagocytosis of latex particles human polymorphonuclear leukocytes (PMNs) release a product that generates chemotactic activity from fresh human serum. Release of this product is maximal at 20-30 min of phagocytosis. It is present in resting PMNs, may be recovered from granule fractions, and functions at physio...

journal_title：Inflammation

authors： Wright DG,Gallin JI

更新日期：1975-03-01 00:00:00

abstract：:NSAIDs are widely used to alleviate the symptoms of OA. It remains controversial as to what effects these agents have on the progression of OA. In vitro studies showed several types of NSAIDs (e.g., sodium salicylate, indomethacin) inhibited the synthesis of cartilage matrix component, but some types of NSAIDs (e.g., ...

journal_title：Inflammation

authors： Ding C

更新日期：2002-06-01 00:00:00

abstract：:The present study aimed at characterizing the phenotype and functions of adherent synovial fluid (SF) cells derived from rheumatoid arthritis (RA), comparing with fibroblast-like synoviocytes (FLS) derived from RA synovial tissue (ST). Adherent SF-derived cells were spindle-shaped from passages 1-6 under light microsc...

journal_title：Inflammation

authors： Ahn JK,Kim H,Lee J,Bae EK,Cha HS,Koh EM

更新日期：2008-12-01 00:00:00

abstract：:An acute neutrophilic lung injury was compared in Balb/c normal and nu/nu (nude) mice to assess the role of T lymphocytes in the resolution of acute pulmonary neutrophilic inflammation following the administration of endotoxin. Maximal neutrophilic infiltration occurred on day 1 post-endotoxin treatment and declined t...

journal_title：Inflammation

authors： Morris PE,Glass J,Cross R,Cohen DA

更新日期：1997-06-01 00:00:00

abstract：:The respiratory epithelium is often exposed to oxidant gases, including ozone from photochemical smog and toxic oxygen metabolites released from neutrophils recruited in conditions of airway inflammation. We evaluated DNA single strand break formation by alkaline elution as a measure of oxidant-induced DNA damage to b...

journal_title：Inflammation

authors： McDonald RJ,Pan LC,St George JA,Hyde DM,Ducore JM

更新日期：1993-12-01 00:00:00

abstract：:This study investigated the protective effect of Lactobacillus plantarum NDC 75017 (L. plantarum NDC 75017) against acute liver injury induced by lipopolysaccharide (LPS). Thirty male mice were randomly divided into the control, LPS, and LPS + L. plantarum NDC 75017 groups. In the LPS + L. plantarum group, the mice we...

journal_title：Inflammation

authors： Peng X,Jiang Y

更新日期：2014-10-01 00:00:00

abstract：:Rheumatoid synovial fluids generated significantly greater amounts of superoxide, lysosomal enzymes, and superoxide dismutase from neutrophils into extracellular fluid than osteoarthritic synovial fluids. Rheumatoid factors isolated from serum suppressed superoxide-generating activity of performed immune complexes, bu...

journal_title：Inflammation

authors： Shingu M,Todoroki T,Nobunaga M

更新日期：1987-06-01 00:00:00

abstract：:Praeruptorin C, D, and E (PC, PD, and PE) are three pyranocoumarins isolated from the dried root of Peucedanum praeruptorum Dunn of Umbelliferae. In the present study, we investigated the anti-inflammatory effect of these compounds in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophage cells. Pyranocoumarins signi...

journal_title：Inflammation

authors： Yu PJ,Jin H,Zhang JY,Wang GF,Li JR,Zhu ZG,Tian YX,Wu SY,Xu W,Zhang JJ,Wu SG

更新日期：2012-06-01 00:00:00

abstract：:Kurloff cells are mononuclear cells possessing a large cytoplasmic inclusion body specific to the guinea pig. In this report, we present strong evidence that Kurloff cells can mediate NC activity against tumor cells in addition to their previously reported NK activity. Using an 18 h 51Cr-release assay we have shown th...

journal_title：Inflammation

authors： Pouliot N,Maghni K,Sirois P,Rola-Pleszczynski M

更新日期：1996-06-01 00:00:00

abstract：:Previous studies have suggested that Interleukin-6 (IL-6) acts as a marker of vasculitis. To determine the role of IL-6 in vasculitis we utilized two models of immune complex induced vascular injury (dermal Arthus and acute pulmonary alveolitis) in IL-6 deficient (IL-6(-/-)) and IL-6 sufficient (IL-6(+/+)) mice. Plasm...

journal_title：Inflammation

authors： McClintock SD,Barron AG,Olle EW,Deogracias MP,Warner RL,Opp M,Johnson KJ

更新日期：2005-12-01 00:00:00

abstract：:Stacks of six membrane filters (8-mu pore size) were placed over the mouths of plastic tubes. The tubes were filled with casein (test) or NaCl (control) solution and implanted subcutaneously in white rats; each animal received one tube with casein and one control tube. After 12, 18, 24, and 36 h, the tubes were remove...

journal_title：Inflammation

authors： Egger G,Porta S,Gollmann D

更新日期：1982-06-01 00:00:00

abstract：:Low-grade chronic systemic inflammation is often associated with chronic non-communicable diseases, and its most frequently used marker, the C-reactive protein (CRP), has become an identifier of such diseases as well as an independent predictor for cardiovascular disorders and mortality. CRP is produced in response to...

journal_title：Inflammation

authors： Moreto F,de Oliveira EP,Manda RM,Torezan GA,Teixeira O,Michelin E,Burini RC

更新日期：2013-02-01 00:00:00

abstract：:We analyzed the influence of heparins (unfractionated heparin, UFH and low molecular weight heparin certoparin) on the generation of IL-1ra, IL-6, IL-10, and IL-12p40 and from leukocyte fractions in vitro. Polymorphonuclear neutrophil leukocytes (PMN) and peripheral blood mononuclear cells (PBMC) from 16 different hea...

journal_title：Inflammation

authors： Köller M,Kutscha-Lissberg F,Brom J,Weidinger G,Muhr G

更新日期：2001-10-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is a chronic inflammation that can lead to loss of range of joint abnormalities in severe cases. Diosgenin has anti-inflammatory effects. This paper discussed the effect and mechanism of diosgenin on excessive proliferation and inflammatory response of synovial cells in RA. CCK-8 detected the...

journal_title：Inflammation

authors： Wang R,Sun Y,Jin X,Wen W,Cao Y

更新日期：2020-11-25 00:00:00

abstract：:The biological effects of asiatic acid (AA) on spinal cord injury (SCI)-induced acute lung injury (ALI) have not been investigated. We aimed to investigate the therapeutic efficacy and molecular mechanisms of AA on SCI-induced ALI. One-hundred and fifty Sprague-Dawley rats were randomly assigned to five groups: sham, ...

journal_title：Inflammation

authors： Jiang W,Li M,He F,Yao W,Bian Z,Wang X,Zhu L

更新日期：2016-12-01 00:00:00

abstract：:Injury to podocytes leads to proteinuria, a hallmark of most glomerular diseases as well as being associated with the progression of kidney disease. Activation of the Wnt/β-catenin pathway is associated with the pathogenesis of podocyte dysfunction and can play a role in renal injury. Furthermore, the expression of fr...

journal_title：Inflammation

authors： Senouthai S,Wang J,Fu D,You Y

更新日期：2019-08-01 00:00:00

abstract：:After severe burns, a wound revision is often done to remove devitalized tissue and minimize bacterial growth. After such revision, the patient may show signs of sepsis. In a group of burned patients we found a transient endotoxemia, and a subsequent leukocyte activation, monitored as increased expression of the beta ...

journal_title：Inflammation

authors： Ljunghusen O,Berg S,Hed J,Lundahl J,Nettelblad H,Sjögren F,Stendahl O

更新日期：1995-08-01 00:00:00

abstract：:The adhesive interactions between phagocytes and endothelial cells (EC) can be modulated by inflammatory cytokines and chemotactic proteins which are released during an inflammatory response. The aim of the present study was to investigate first whether the adhesive properties of granulocytes and monocytes from asthma...

journal_title：Inflammation

authors： Verdegaal EM,Zegveld ST,Beekhuizen H,Bakker W,van Furth R

更新日期：1998-04-01 00:00:00

abstract：:Central nervous system tuberculosis (CNS-TB) is caused by infection with Mycobacterium tuberculosis (Mtb). The inflammatory response following CNS-TB involves the activation of resident microglia and the infiltration of macrophages. However, it has not been clarified whether microglia can be polarized into the classic...

journal_title：Inflammation

authors： Qin Y,Sun X,Shao X,Cheng C,Feng J,Sun W,Gu D,Liu W,Xu F,Duan Y

更新日期：2015-08-01 00:00:00

abstract：:Induction of colitis by 2,4,6-Trinitrobenzenesulphonic acid (TNB) in the rat is a widely used experimental model of inflammatory bowel disease. Action of TNB as a hapten, induces colitis involving infiltration of colonic mucosa by neutrophils and macrophages and increased production of inflammatory mediators. The aim ...

journal_title：Inflammation

authors： Kankuri E,Asmawi MZ,Korpela R,Vapaatalo H,Moilanen E

更新日期：1999-04-01 00:00:00

abstract：:Currently, only tumor necrosis factor alpha (TNF-α) and interleukin family cytokines have been found to be elicited in Vibrio vulnificus (V. vulnificus)-infected animal models and humans. However, multiple other cytokines are also involved in the immune and inflammatory responses to foreign microorganism infection. An...

journal_title：Inflammation

authors： Liu XF,Wu J,Wang MY,Chen YJ,Cao Y,Hu CJ

更新日期：2015-10-01 00:00:00