Abstract:
:The present study was performed to explore the effect of aqueous extract of Aloe vera on behavioural parameters of pain. Pain assessment was performed by the tail-flick and formalin tests. A. vera (100 mg/kg, per oral (p.o.)) produced an insignificant decrease in the pain response in the tail-flick and formalin tests. Moreover, A. vera (200 and 400 mg/kg, p.o.) did not have significant effect on the tail-flick test. However, A. vera (200 and 400 mg/kg, p.o.) significantly decreased the second phase of the formalin-induced pain. Thus, these findings suggest that A. vera exerts its effect by a peripheral mechanism of action rather than central.
journal_name
Inflammationjournal_title
Inflammationauthors
Rathor N,Mehta AK,Sharma AK,Mediratta PK,Sharma KKdoi
10.1007/s10753-012-9512-zsubject
Has Abstractpub_date
2012-12-01 00:00:00pages
1900-3issue
6eissn
0360-3997issn
1573-2576journal_volume
35pub_type
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