Methamphetamine and amphetamine concentrations in postmortem rabbit tissues.

Abstract:

:The feasibility of detecting methamphetamine and its major metabolite, amphetamine, in postmortem tissues over a 2-year period was examined. It is important to determine if the abuse and toxic effects of drugs can be proved from evidence found in decayed, submerged, or stained tissue materials. The blood, urine, liver, skeletal muscle, skin and extremity bones from rabbits given methamphetamine intravenously were kept at room temperature, under 4 different conditions: sealed in a test tube, dried in the open air, submerged in tap water and stained on gauze. Methamphetamine was present in all the samples, with slight change in concentration in case of sealed and air dried tissues. Changes varied in bones kept in water. There were considerable decreases in methamphetamine in blood and urine stains. Despite long term storage, drug abuse and/or toxicity could be determined, in all tissues examined.

journal_name

Forensic Sci Int

authors

Nagata T,Kimura K,Hara K,Kudo K

doi

10.1016/0379-0738(90)90270-9

subject

Has Abstract

pub_date

1990-11-01 00:00:00

pages

39-47

issue

1

eissn

0379-0738

issn

1872-6283

pii

0379-0738(90)90270-9

journal_volume

48

pub_type

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