Comparison of total splenic artery embolization and partial splenic embolization for hypersplenism.

Abstract:

AIM:To evaluate whether total splenic artery embolization (TSAE) for patients with hypersplenism delivers better long-term outcomes than partial splenic embolization (PSE). METHODS:Sixty-one patients with hypersplenism eligible for TSAE (n = 27, group A) or PSE (n = 34, group B) were enrolled into the trial, which included clinical and computed tomography follow-up. Data on technical success, length of hospital stay, white blood cell (WBC) and platelet (PLT) counts, splenic volume and complications were collected at 2 wk, 6 mo, and 1, 2, 3, 4 years postoperatively. RESULTS:Both TSAE and PSE were technically successful in all patients. Complications were significantly fewer (P = 0.001), and hospital stay significantly shorter (P = 0.007), in group A than in group B. Post-procedure WBC and PLT counts in group A were significantly higher than those in group B from 6 mo to 4 years (P = 0.001), and post-procedure residual splenic volume in group A was significantly less than that observed in group B at 1, 2, 3 and 4 years post-procedure (P = 0.001). No significant differences were observed in red blood cell counts and liver function parameters between the two groups following the procedure. CONCLUSION:Our results indicate that TSAE for patients with hypersplenism not only delivers a better long-term outcome, but is also associated with lower complication rates and a shorter hospital stay than PSE.

journal_name

World J Gastroenterol

authors

He XH,Gu JJ,Li WT,Peng WJ,Li GD,Wang SP,Xu LC,Ji J

doi

10.3748/wjg.v18.i24.3138

subject

Has Abstract

pub_date

2012-06-28 00:00:00

pages

3138-44

issue

24

eissn

1007-9327

issn

2219-2840

journal_volume

18

pub_type

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