当前位置： SCI文献检索 > JOURNAL OF CARDIAC FAILURE期刊下所有文献 > Plasma pro-B-type natriuretic peptide testing as a screening method for hypertrophic cardiomyopathy.

Plasma pro-B-type natriuretic peptide testing as a screening method for hypertrophic cardiomyopathy.

Abstract：

BACKGROUND:Clinical multistage risk assessment associated with electrocardiogram (ECG) and NT-proBNP may be a feasible strategy to screen hypertrophic cardiomyopathy (HCM). We investigated the effectiveness of a screening based on ECG and NT-proBNP in first-degree relatives of patients with HCM. METHODS AND RESULTS:A total of 106 first-degree relatives were included. All individuals were evaluated by echocardiography, ECG, NT-proBNP, and molecular screening (available for 65 individuals). From the 106 individuals, 36 (34%) had diagnosis confirmed by echocardiography. Using echocardiography as the gold standard, ECG criteria had a sensitivity of 0.71, 0.42, and 0.52 for the Romhilt-Estes, Sokolow-Lyon, and Cornell criteria, respectively. Mean values of NT-ProBNP were higher in affected as compared with nonaffected relatives (26.1 vs. 1290.5, P < .001). The AUC of NT-proBNP was 0.98. Using a cutoff value of 70 pg/mL, we observed a sensitivity of 0.92 and specificity of 0.96. Using molecular genetics as the gold standard, ECG criteria had a sensitivity of 0.67, 0.37, and 0.42 for the Romhilt-Estes, Sokolow-Lyon, and Cornell criteria, respectively. Using a cutoff value of 70 pg/mL, we observed a sensitivity of 0.83 and specificity of 0.98. CONCLUSION:Values of NT-proBNP above 70 pg/mL can be used to effectively select high-risk first-degree relatives for HCM screening.

journal_name

J Card Fail

journal_title

Journal of cardiac failure

authors

Fernandes F,Arteaga-Fernandez E,Antunes Mde O,Buck P,Marsiglia JD,Matsumoto A,Nastari L,Krieger JE,Pereira AC,Mady C

doi

10.1016/j.cardfail.2012.04.005

subject

Has Abstract

pub_date

2012-07-01 00:00:00

pages

564-8

issue

7

eissn

1071-9164

issn

1532-8414

pii

S1071-9164(12)00120-0

journal_volume

18

pub_type

杂志文章

相关文献

JOURNAL OF CARDIAC FAILURE文献大全
  • Symptoms characteristic of heart failure among CKD patients without diagnosed heart failure.

    abstract：BACKGROUND:Epidemiological studies typically diagnose heart failure (HF) at the time of hospitalization, and have not evaluated the prevalence of HF symptoms in CKD patients without a prior HF diagnosis. METHODS AND RESULTS:We modified the Kansas City Cardiomyopathy Questionnaire (KCCQ) to detect and quantify symptoms...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2010.08.009

    authors： Shlipak MG,Lash JP,Yang W,Teal V,Keane M,Cappola T,Keller C,Jamerson K,Kusek J,Delafontaine P,He J,Miller ER 3rd,Schreiber M,Go AS,CRIC Investigators.

    更新日期：2011-01-01 00:00:00

  • Baseline Characteristics Predict the Presence of Amyloid on Endomyocardial Biopsy.

    abstract：BACKGROUND:Recent studies have suggested a high prevalence of cardiac amyloidosis (CAm) in heart failure (HF) patients. CAm might be underdiagnosed owing to low clinical suspicion. METHODS AND RESULTS:We performed retrospective analysis of 259 patients with HF and ejection fraction (EF) ≥50% referred for endomyocardia...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2016.12.006

    authors： Ton VK,Bhonsale A,Gilotra NA,Halushka MK,Steenbergen C,Almansa J,Brown E,Tedford RJ,Wittstein I,Sharma K,Russell SD,Judge DP

    更新日期：2017-04-01 00:00:00

  • Decoupling Between Diastolic Pulmonary Arterial Pressure and Pulmonary Arterial Wedge Pressure at Incremental Left Ventricular Assist Device (LVAD) Speeds Is Associated With Worse Prognosis After LVAD Implantation.

    abstract：BACKGROUND:Decoupling between diastolic pulmonary arterial pressure (dPAP) and pulmonary arterial wedge pressure (PAWP) is an index of pulmonary vasculature remodeling and provides prognostic information. Furthermore, decoupling may change during incremental left ventricular assist device (LVAD) speed changes. METHODS...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2018.08.003

    authors： Imamura T,Kim G,Raikhelkar J,Sarswat N,Kalantari S,Smith B,Rodgers D,Chung B,Nguyen A,Ota T,Song T,Juricek C,Jeevanandam V,Burkhoff D,Sayer G,Uriel N

    更新日期：2018-09-01 00:00:00

  • Cardiovascular magnetic resonance imaging detects cardiac involvement in Churg-Strauss syndrome.

    abstract：BACKGROUND:Cardiac involvement in Churg-Strauss vasculitis worsens the prognosis. Early detection is, therefore, warranted. Cardiac magnetic resonance (CMR) can visualize various forms of inflammatory changes in the myocardium. We tested whether CMR could elucidate cardiac damage in patients with biopsy-proven Churg-St...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2008.07.227

    authors： Wassmuth R,Göbel U,Natusch A,Schneider W,Kettritz R,Dietz R,Luft FC,Schulz-Menger J

    更新日期：2008-12-01 00:00:00

  • Age, but not sex, influences the measurement of ejection fraction in elderly patients hospitalized for heart failure.

    abstract：BACKGROUND:Current US and European guidelines recommend that ejection fraction (EF) be measured at least once in patients with congestive heart failure (CHF). However, it is not known how age and sex influence adherence to this recommendation. METHODS:We reviewed a national sample of Medicare patients discharged with ...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1054/jcaf.2003.16

    authors： Lindenfeld J,Fiske KS,Stevens BR,Debuhr J,Havranek EP,Abrams FR

    更新日期：2003-04-01 00:00:00

  • Activities and Compensation of Advanced Heart Failure Specialists: Results of the Heart Failure Society of America (HFSA) Survey.

    abstract：BACKGROUND:In the current era, where advanced heart failure (AHF) has become an American Board of Internal Medicine-certified subspecialty, new data are needed to benchmark and value levels of clinical effort performed by AHF specialists (AHFMDs). METHODS AND RESULTS:A 36-question survey was sent to 728 AHFMDs, member...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2015.08.340

    authors： Klein L,Greenberg BH,Konstam MA,Gregory D,Kociol RD,Johnson MR,de Marco T

    更新日期：2015-11-01 00:00:00

  • Effects of different degrees of sympathetic antagonism on cytokine network in patients with ischemic dilated cardiomyopathy.

    abstract：BACKGROUND:The proinflammatory cytokines have been implicated in the pathogenesis of heart failure. Recent studies have shown that beta-adrenergic blockade can modulate cytokine production. This study investigates the different impact of different degrees of sympathetic antagonism on circulating levels of cytokines in ...

    journal_title：Journal of cardiac failure

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/j.cardfail.2004.07.006

    authors： Cinquegrana G,D'Aniello L,Landi M,Spinelli L,Grande G,De Prisco F,Petretta M

    更新日期：2005-04-01 00:00:00

  • Left ventricular remodeling and myocardial recovery on mechanical circulatory support.

    abstract：BACKGROUND:Myocardial recovery after ventricular assist devices (VAD) is rare but appears more common in nonischemic cardiomyopathies (NICM). We sought to evaluate left ventricular (LV) end diastolic diameter (LVEDD) for predicting recovery after VAD. METHODS AND RESULTS:NICM patients receiving long-term mechanical su...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2009.10.018

    authors： Simon MA,Primack BA,Teuteberg J,Kormos RL,Bermudez C,Toyoda Y,Shah H,Gorcsan J 3rd,McNamara DM

    更新日期：2010-02-01 00:00:00

  • Results of the Prospective Minnesota Study of ECHO/TDI in Cardiac Resynchronization Therapy (PROMISE-CRT) study.

    abstract：BACKGROUND:Retrospective single-center studies have shown that measures of mechanical dyssynchrony before cardiac resynchronization therapy (CRT), or acute changes after CRT, predict response better than QRS duration. The Prospective Minnesota Study of Echocardiographic/TDI in Cardiac Resynchronization Therapy (PROMISE...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.cardfail.2008.12.009

    authors： Bank AJ,Kaufman CL,Kelly AS,Burns KV,Adler SW,Rector TS,Goldsmith SR,Olivari MT,Tang C,Nelson L,Metzig A,PROMISE-CRT Investigators.

    更新日期：2009-06-01 00:00:00

  • Prolonged electrical muscle stimulation exercise improves strength, peak VO2, and exercise capacity in patients with stable chronic heart failure.

    abstract：BACKGROUND:Exercise training can help patients with chronic heart failure but may be limited in its applicability due to age and other comorbidities. This investigation evaluated training responses to prolonged electrical muscle stimulation (EMS) in patients with stable chronic heart failure. METHODS AND RESULTS:In a ...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.cardfail.2008.11.005

    authors： Banerjee P,Caulfield B,Crowe L,Clark AL

    更新日期：2009-05-01 00:00:00

  • Carvedilol improves left atrial and left ventricular function and reserve in dilated cardiomyopathy after 1 year of treatment.

    abstract：BACKGROUND:The aim of this study was to evaluate the effects of carvedilol therapy on left atrial (LA) function in patients with heart failure from nonischemic dilated cardiomyopathy. METHODS AND RESULTS:Thirty-five patients (42.4 +/- 13.5 years) in New York Heart Association functional Class II-III have been studied....

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2006.10.011

    authors： Paraskevaidis I,Farmakis D,Parissis JT,Dodouras T,Filippatos G,Tsiapras D,Kremastinos DT

    更新日期：2007-03-01 00:00:00

  • Effect of acute β-blocker withholding on ventilatory efficiency in patients with advanced chronic heart failure.

    abstract：BACKGROUND:This is the first study to examine the effect of acute (24-hour) beta-blocker withholding on ventilatory efficiency in patients with advanced chronic heart failure (CHF) during maximal incremental treadmill cardiopulmonary exercise test. METHODS AND RESULTS:Seventeen CHF patients were studied either 3 hours...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.cardfail.2010.02.006

    authors： Laveneziana P,Agostoni P,Mignatti A,Mushtaq S,Colombo P,Sims D,Uriel N,Jorde UP

    更新日期：2010-07-01 00:00:00

  • Hemodynamic ranges during daily activities and exercise testing in patients with pulmonary arterial hypertension.

    abstract：BACKGROUND:In patients with pulmonary arterial hypertension (PAH) the relationship between hemodynamic impairment experienced during daily activity and that during exercise testing is not known. METHODS AND RESULTS:Ten PAH patients received an implantable hemodynamic monitor that continuously recorded and stored right...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2014.04.019

    authors： Kjellström B,Frantz RP,Benza RL,Bennett T,Bourge RC,McGoon MD

    更新日期：2014-07-01 00:00:00

  • ACCF/AHA/HFSA 2011 survey results: current staffing profile of heart failure programs, including programs that perform heart transplant and mechanical circulatory support device implantation.

    abstract：OBJECTIVES:There have been no published recommendations about staffing needs for a heart failure (HF) clinic or an office setting focused on heart transplant. The goal of this survey was to understand the current staffing environment of HF, transplant, and mechanical circulatory support device (MCSD) programs in the Un...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.cardfail.2011.04.001

    authors： Jessup M,Albert NM,Lanfear DE,Lindenfeld J,Massie BM,Walsh MN,Zucker MJ,ACCF Heart Failure and Transplant Committee.,AHA Heart Failure and Transplantation Committee.,Heart Failure Society of America.

    更新日期：2011-05-01 00:00:00

  • Effects of glucocorticoids in potentiating diuresis in heart failure patients with diuretic resistance.

    abstract：:Diuretic resistance in heart failure is defined as a state in which diuretic response is diminished or lost before the therapeutic goal of relief from congestion has been reached. Diuretic resistance is very common and is associated with poor outcomes. Over the past decade, several new drugs and devices targeting deco...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章,评审

    doi：10.1016/j.cardfail.2014.06.353

    authors： Liu C,Liu K

    更新日期：2014-09-01 00:00:00

  • Atrial fibrillation impairs endothelial function of forearm vessels in humans.

    abstract：BACKGROUND:Although there have been many studies on the effects of atrial fibrillation (AF) on cardiac function, few studies have been done on its effects on endothelial function. The present study was designed to examine the effects of AF on endothelial function in human subjects. METHODS AND RESULTS:Changes in forea...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1054/jcaf.2001.22107

    authors： Takahashi N,Ishibashi Y,Shimada T,Sakane T,Ohata S,Sugamori T,Ohta Y,Inoue S,Nakamura K,Shimizu H,Katoh H,Sano K,Murakami Y,Hashimoto M

    更新日期：2001-03-01 00:00:00

  • Endothelial nitric oxide synthase (NOS3) polymorphisms in African Americans with heart failure: results from the A-HeFT trial.

    abstract：BACKGROUND:Genetic heterogeneity at the endothelial nitric oxide synthase (NOS3) locus influences heart failure outcomes. The prevalence of NOS3 variants differs in black and white cohorts, but the impact of these differences is unknown. METHODS AND RESULTS:Subjects (n = 352) in the Genetic Risk Assessment of Heart Fa...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.cardfail.2008.10.028

    authors： McNamara DM,Tam SW,Sabolinski ML,Tobelmann P,Janosko K,Venkitachalam L,Ofili E,Yancy C,Feldman AM,Ghali JK,Taylor AL,Cohn JN,Worcel M

    更新日期：2009-04-01 00:00:00

  • Left Ventricular Deformation and Myocardial Fibrosis in Patients With Advanced Heart Failure Requiring Transplantation.

    abstract：PURPOSE:To evaluate potential relationships between different components of left ventricular (LV) function and histopathological evidence for myocardial fibrosis in patients undergoing heart transplantation. METHODS:The study population included patients with advanced heart failure, referred for an echocardiographic e...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2016.02.012

    authors： Cameli M,Mondillo S,Righini FM,Lisi M,Dokollari A,Lindqvist P,Maccherini M,Henein M

    更新日期：2016-11-01 00:00:00

  • Proposal for a new clinical end point to evaluate the efficacy of drugs and devices in the treatment of chronic heart failure.

    abstract：:Clinical trials designed to evaluate the effect of drugs and devices on the symptoms and clinical status in chronic heart failure have frequently produced conflicting, inconclusive, or misleading results. These difficulties can be explained by the fact that previous studies have relied on efficacy measures that have i...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1054/jcaf.2001.25652

    authors： Packer M

    更新日期：2001-06-01 00:00:00

  • Increased Urinary Liver-Type Fatty Acid-Binding Protein Level Predicts Worsening Renal Function in Patients With Acute Heart Failure.

    abstract：BACKGROUND:Urinary liver-type fatty acid-binding protein (L-FABP) is a potential biomarker for acute kidney injury, and it in turn increases cardiovascular mortality. We tested whether the urinary L-FABP level predicted short- and mid-term outcomes in patients with acute heart failure. METHODS AND RESULTS:We enrolled ...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2018.07.003

    authors： Okubo Y,Sairaku A,Morishima N,Ogi H,Matsumoto T,Kinoshita H,Kihara Y

    更新日期：2018-08-01 00:00:00

  • Polymorphisms of matrix metalloproteinases in systolic heart failure: role on disease susceptibility, phenotypic characteristics, and prognosis.

    abstract：BACKGROUND:The role of matrix metalloproteinases (MMPs) polymorphisms on heart failure (HF) susceptibility, phenotypic characteristics, and prognosis has been poorly explored. METHODS AND RESULTS:We studied 313 HF patients with left ventricular systolic dysfunction and 367 healthy control subjects. Genotyping of MMP-1...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2010.09.017

    authors： Velho FM,Cohen CR,Santos KG,Silvello D,Martinelli N,Biolo A,Clausell N,Rohde LE

    更新日期：2011-02-01 00:00:00

  • Selective microembolization of the circumflex coronary artery in an ovine model: Dilated, ischemic cardiomyopathy and left ventricular dysfunction.

    abstract：BACKGROUND:Ventricular remodeling often occurs after myocardial infarction, yet the natural history remains unpredictable because of the chronicity of the process and therapeutic interventions involved. We induced cardiac dysfunction in an ovine model via selective microembolization of the circumflex coronary artery (L...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2003.08.013

    authors： Monreal G,Gerhardt MA,Kambara A,Abrishamchian AR,Bauer JA,Goldstein AH

    更新日期：2004-04-01 00:00:00

  • Relationship between pulmonary capillary wedge V wave and transmitral and pulmonary venous flow velocity patterns in various heart diseases.

    abstract：BACKGROUND:A large V wave in a pulmonary capillary wedge pressure (PCWP) tracing is characteristic of mitral regurgitation. However, the V wave is often increased in patients without or with no significant mitral regurgitation. METHODS AND RESULTS:The V wave was in the PCWP tracing investigated in 65 patients using tr...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/s1071-9164(96)80044-3

    authors： Kageji Y,Oki T,Iuchi A,Tabata T,Ito S

    更新日期：1996-09-01 00:00:00

  • Fibrosis and Fibrotic Gene Expression in Pediatric and Adult Patients With Idiopathic Dilated Cardiomyopathy.

    abstract：BACKGROUND:Although fibrosis seems to be prognostic for adverse outcomes in adults with idiopathic dilated cardiomyopathy (IDC), little is known about the prevalence and development of fibrosis in pediatric IDC hearts. We hypothesized that there is less activation of fibrosis at a molecular level in pediatric IDC heart...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2016.11.006

    authors： Woulfe KC,Siomos AK,Nguyen H,SooHoo M,Galambos C,Stauffer BL,Sucharov C,Miyamoto S

    更新日期：2017-04-01 00:00:00

  • Quality of care and hospital readmission in congestive heart failure: an explicit review process.

    abstract：BACKGROUND:The effect of hospital quality of care on hospital readmission for patients with congestive heart failure (CHF) has not been widely studied. METHODS AND RESULTS:We examined the effects of clinical factors, hospital quality of care, and cardiologist involvement on 3-month readmission rates in patients with C...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1054/jcaf.2001.28931

    authors： Polanczyk CA,Newton C,Dec GW,Di Salvo TG

    更新日期：2001-12-01 00:00:00

  • Pulmonary hypertension and systemic hypotension as limitations to exercise in chronic heart failure.

    abstract：:The authors have previously shown that the resistance ratio (RR) is increased in patients with congestive heart failure (CHF), and that the patients with the highest RRs have an increased mortality. The authors hypothesized that CHF patients with the lowest maximum oxygen consumption and the most impaired Weber functi...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/1071-9164(94)90005-1

    authors： Mabee SW,Metra M,Reed DE,Dei Cas L,Cody RJ

    更新日期：1994-10-01 00:00:00

  • Anabolics and cardiomyopathy in a bodybuilder: case report and literature review.

    abstract：BACKGROUND:Athletes use androgenic-anabolic steroids to increase strength and muscle mass. Several case reports suggest that it may lead to dilated cardiomyopathy. METHODS AND RESULTS:We report a case of a 41-year-old bodybuilder with severe systolic dysfunction and Class IV heart failure despite maximal medical thera...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章,评审

    doi：10.1016/j.cardfail.2008.12.014

    authors： Ahlgrim C,Guglin M

    更新日期：2009-08-01 00:00:00

  • Effects of lisinopril in patients with heart failure and chronic atrial fibrillation.

    abstract：:Although atrial fibrillation is common in patients with heart failure, patients with atrial fibrillation are often excluded from congestive heart failure trials or are not analyzed separately. Consequently, while the effect of angiotensin-converting enzyme inhibitors in patients with sinus rhythm is well established, ...

    journal_title：Journal of cardiac failure

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s1071-9164(05)80004-1

    authors： Van Den Berg MP,Crijns HJ,Van Veldhuisen DJ,Griep N,De Kam PJ,Lie KI

    更新日期：1995-12-01 00:00:00

  • Identification of Heart Failure Events in Medicare Claims: The Atherosclerosis Risk in Communities (ARIC) Study.

    abstract：BACKGROUND:We examined the accuracy of Medicare heart failure (HF) diagnostic codes in the identification of acute decompensated (ADHF and chronic stable (CSHF) HF. METHODS AND RESULTS:Hospitalizations were identified from medical discharge records for Atherosclerosis Risk in Communities (ARIC) study participants with...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2015.07.013

    authors： Kucharska-Newton AM,Heiss G,Ni H,Stearns SC,Puccinelli-Ortega N,Wruck LM,Chambless L

    更新日期：2016-01-01 00:00:00

  • Association between physical activity measurements and key parameters of cardiopulmonary exercise testing in patients with heart failure.

    abstract：BACKGROUND:A hallmark characteristic of heart failure (HF) is reduced physical activity (PA) patterns. The relationship between key cardiopulmonary exercise testing (CPX) variables and PA patterns has not been investigated. Therefore, we evaluated PA patterns in patients with ischemic HF and its relationship to peak ox...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2013.08.002

    authors： da Silva VZ,Lima AC,Vargas FT,Cahalin LP,Arena R,Cipriano G Jr

    更新日期：2013-09-01 00:00:00