Abstract：
OBJECTIVE:To describe the clinical spectrum and factors associated with poor short-term outcomes in children with interstitial lung disease (ILD). DESIGN:Retrospective chart review SETTING:Pediatric Chest Clinic of a tertiary care hospital METHODOLOGY:We retrieved information regarding clinical course and laboratory features of all children diagnosed as ILD between January 1999 and February 2010. Disease severity was assessed using ILD score based on clinical features and SpO2 at the time of initial evaluation. Outcome was assessed after 3 months of initial diagnosis as improved or death/no improvement in symptoms. RESULTS:90 children (median age, 6.8 years; 62% boys) were diagnosed to have ILD during this period. 46 children were classified as having definite ILD while 44 had possible ILD. The commonest clinical features at presentation were cough (82.2%), dyspnea (80%), pallor (50%), and crackles (45.6%). 3 children (3.3%) died while 21 (23%) showed no improvement in clinical status on follow-up at 3 months. A higher ILD score (RR 3.72, 95% CI 1.4, 9.9) and lower alkaline phosphatase levels (median [IQR]: 205 [175.2] vs. 360 [245.7]; P=0.006) were found to be significantly associated with worse outcomes. CONCLUSION:The common clinical features of ILD in our study included breathlessness, cough and hypoxemia. A working diagnosis of ILD can be made with the help of imaging, bronchoscopy, or lung biopsy. A simple score based on clinical findings and pulse-oximetry might predict those children with poor short-term outcome.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Sankar J,Pillai MS,Sankar MJ,Lodha R,Kabra SKdoi
10.1007/s13312-013-0034-zsubject
Has Abstractpub_date
2013-01-08 00:00:00pages
127-33issue
1eissn
0019-6061issn
0974-7559pii
S097475591101056-1journal_volume
50pub_type
杂志文章abstract：:This retrospective study was conducted to estimate the shedding of 2009 H1N1 virus and the risk analysis by review of medical charts, laboratory and radiological findings of all inpatients with confirmed pandemic influenza A (H1N1) at a provincial pediatric hospital. A total of 41 cases attending the inpatient departm...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-011-0151-5
更新日期：2011-12-01 00:00:00
abstract：:The incidence and the factors that influence twinning were studied in six villages of Dholka Taluka, a rural field training centre. The twinning rate was 10.10 per 1000 maternities. The monozygotic and dizygotic twinning rates were 4.53 and 5.56, respectively by applying Weinberg's differential formula. In three fourt...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1990-03-01 00:00:00
abstract：OBJECTIVE:To assess the levels of free oxygen radicals in acute renal failure and their predictive value in clinical outcome. DESIGN:Prospective. SETTING:Intensive care unit. METHODS:Study was conducted in 50 children (25 with acute renal failure and 25 age and sex matched controls). Blood urea, serum creatinine, se...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2000-02-01 00:00:00
abstract：:The clinical, laboratory and therapeutic data of patients with diarrhea in Human immunodeficiency virus (HIV) antibody positive, immunocompromised and immunocompetent individuals were studied especially to look for prevalence of intestinal coccidiosis. During a study period of one decade, Isospora belli were identifie...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2002-10-01 00:00:00
abstract：OBJECTIVE:To describe the utility of flexible fiberoptic bronchoscopy for the diagnosis and management in the neonatal ICU. METHODS:A retrospective, medical chart review was conducted in neonates who underwent flexible fiberoptic bronchoscopy over a period of 7 years. Besides demographic data and diagnostic findings, ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2019-07-15 00:00:00
abstract：:Meropenem is a new carbapenem antibacterial agent with wide spectrum of activity against gram-negative, gram-positive and anaerobic organisms. It is stable against most beta-lactamases produced by gram-negative bacteria and has greatest utility in treating severe infections in hospitalized children. It has good CSF pe...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：
更新日期：2005-05-01 00:00:00
abstract：:This cross-sectional study was undertaken to compare WHO and Indian Academy of Pediatrics (IAP) recommended growth charts compiled by Agarwal. 2105 children aged less than 5 years, attending 132 Anganwadi centres in Mysore city, were included by simple random sampling method. Weight and height of all children were rec...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-012-0157-7
更新日期：2012-09-01 00:00:00
abstract：: ...
journal_title：Indian pediatrics
pub_type： 信件
doi：
更新日期：2019-02-15 00:00:00
abstract：OBJECTIVES:To evaluate whether zinc supplements prevent mortality and morbidity in breastfed low birth weight infants. METHODS:All randomized or qausi-randomized trials with individual or cluster allocation and using concurrent controls were included. Study population included LBW infants irrespective of gestational s...
journal_title：Indian pediatrics
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s13312-011-0043-8
更新日期：2011-02-01 00:00:00
abstract：:This presentation deals with 110 surgically proven cases of abdominal tuberculosis in the pediatric age group. The protean clinical profiles and complications of the disease entity made the clinical diagnosis difficult; the investigations were also found non-pathognomonic. The most common type of pathology seen was ad...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1993-09-01 00:00:00
abstract：BACKGROUND:Lysinuric protein intolerance is an inherited disorder of transport of cationic amino acids, causing amino aciduria. CASE CHARACTERISTICS:A 3-year-old boy with 12 month history of episodic change in behavior (decreased sleep, poor interaction), stunted growth and hyperammonemia. OUTCOME:Genetic analysis re...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-016-0920-2
更新日期：2016-08-08 00:00:00
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journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2005-12-01 00:00:00
abstract：OBJECTIVE:To determine the survival of children =18 y, treated with immunosuppressive therapy (IST) using equine antithymocyte globulin (e-ATG) and cyclosporine (CsA). DESIGN:Prospective data entry as per a specified format. SETTING:Tertiary care hospital. PATIENTS:From January 1998 to December 2009, 40 children wer...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-012-0086-5
更新日期：2012-05-01 00:00:00
abstract：:In this cohort study, neurodevelopmental outcome of 20 of 24 surviving very low birth weight infants with sepsis followed up between 2008 and 2009 was compared with 20 control (uninfected infants). We found that plasma interleukin 6 and C reactive protein values were negatively correlated with mental developmental ind...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-013-0091-3
更新日期：2013-03-01 00:00:00
abstract：: ...
journal_title：Indian pediatrics
pub_type： 评论,信件
doi：
更新日期：2018-11-15 00:00:00
abstract：:A 13-year old girl presented with a decade long anemia, diffuse alveolar hemorrhage and interstistial lung disease; was eventually diagnosed as ANCA associated vasculitis. High index of suspicion is thus warranted for alternative diagnosis in chronic anemia, despite increased prevalence of infectious diseases and nutr...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-013-0042-z
更新日期：2013-02-01 00:00:00
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journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2019-08-15 00:00:00
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journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-015-0561-x
更新日期：2015-01-01 00:00:00
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journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2011-02-01 00:00:00
abstract：BACKGROUND:Auxiliary partial orthotopic liver transplantation is a technique where part of diseased native liver is removed and replaced with healthy donor liver so that, the left behind native liver could later regenerate. CASE CHARACTERISTICS:2 year 6 month old girl with acute liver failure due to Hepatitis A. She u...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-016-0795-2
更新日期：2016-01-01 00:00:00
abstract：OBJECTIVE:To describe the clinical characteristics and outcome of Indian children infected with 2009 H1N1 influenza virus. STUDY DESIGN:Retrospective chart review. SETTING:Outpatient department and hospitalized patients in a tertiary care hospital. METHODS:Clinical details of 85 children (positive for the 2009 H1N1 ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-011-0085-y
更新日期：2011-05-01 00:00:00
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journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2006-07-01 00:00:00
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journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
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journal_title：Indian pediatrics
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doi：
更新日期：2006-08-01 00:00:00
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journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1991-06-01 00:00:00
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journal_title：Indian pediatrics
pub_type： 信件
doi：10.1007/s13312-014-0477-x
更新日期：2014-08-01 00:00:00
abstract：OBJECTIVE:To determine the role of intravenous administration of human albumin prior to blood exchange in term neonates for reduction of total serum bilirubin (TSB). DESIGN:Randomized controlled trial. SETTING:Neonatal Unit of Nemazee Hospital, affiliated with Shiraz University of Medical Sciences, southern Iran. PA...
journal_title：Indian pediatrics
pub_type： 杂志文章,随机对照试验
doi：10.1007/s13312-010-0046-x
更新日期：2010-03-01 00:00:00
abstract：BACKGROUND:High bilirubin level is toxic to developing brain and auditory system but the current debate surrounds the toxicity of bilirubin in healthy term infants. METHODS:Longitudinal observational study to find BERA abnormalities in term newborns with isolated hyperbilirubinemia of 20 mg/dL and more and to follow u...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-014-0346-7
更新日期：2014-02-01 00:00:00
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journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2006-05-01 00:00:00
abstract：:This report is based on observations during the conduct of a study of hypocalcemia in infants and children. In a study of 50 cases, 13 exclusively breast fed infants manifesting with hypocalcemic seizures were confirmed to have vitamin D deficiency. None of the 13 infants had received vitamin D supplementation. All of...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2006-03-01 00:00:00
