Abstract:
OBJECTIVE:To determine the role of intravenous administration of human albumin prior to blood exchange in term neonates for reduction of total serum bilirubin (TSB). DESIGN:Randomized controlled trial. SETTING:Neonatal Unit of Nemazee Hospital, affiliated with Shiraz University of Medical Sciences, southern Iran. PATIENTS:Fifty out-born term neonates with gestation age <37 weeks, birth weight <2500 g, otherwise healthy with TSB > or =25 mg/dL requiring blood exchange due to intensive phototherapy failure. INTERVENTION:Intervention group (n=25) received intravenous human albumin 20% (1 g/kg) one hour before exchange while the control group (n=25) underwent a blood exchange. OUTCOME MEASURES:TSB level at 6 and 12 hours post-exchange, total duration of phototherapy, need for a second exchange transfusion and adverse effects. RESULTS:The mean TSB level in albumin-treated group was significantly lower than that in the control group at 6 and 12 hours post-exchange (P<0.001). Mean duration of phototherapy was significantly reduced in the albumin-treated group, compared to that in the control group (8.6+/-2.4 vs. 25+/-8.2 hours) (P<0.001). None of the neonates in albumin-treated group needed exchange transfusion again and no side effects were observed. CONCLUSION:Infusion of 20% albumin (1 g/kg) one hour prior to blood exchange can significantly reduce the post-exchange total serum bilirubin and duration of phototherapy.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Shahian M,Moslehi MAdoi
10.1007/s13312-010-0046-xsubject
Has Abstractpub_date
2010-03-01 00:00:00pages
241-4issue
3eissn
0019-6061issn
0974-7559pii
S097475590800395-1journal_volume
47pub_type
杂志文章,随机对照试验abstract::Fifty two mother-infant pairs were studied. Twenty six of these were delivered by the normal vaginal route (NVD group) and twenty six by Cesarean section (CS group). The NVD babies were roomed in with their mothers soon after birth whereas the CS babies had a mean separation of 2.8 +/- 1.0 days. The mother baby intera...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::We prospectively studied the effect of oral paracetamol in closing hemodynamically significant Patent ductus arteriosus in preterm infants (gestational age <32 weeks) where Ibuprofen was contraindicated. 29 of 40 neonates (72.5%) showed successful response while 11 (29.5%) failed to show any response. No major complic...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2016-02-01 00:00:00
abstract::Fifty two children were immunized with two doses of enhanced potency inactivated polio vaccine in order to determine its efficacy. The vaccine was very efficacious with 92.3, 92.3 and 88.3% of the children seroconverting to the three poliovirus types, respectively. The vaccine was equally efficacious whether the two d...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1992-11-01 00:00:00
abstract::Beta thalassemia is a common genetic disorder in Indians. Around 10,000 thala-ssemia major cases are born every year. The treatment of thalassemia major patients imposes a financial burden on the family. Much progress has been made in last 15 years in understanding of the pathogenesis of thalassemia and development of...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2006-06-01 00:00:00
abstract::In a randomized controlled design, 100 healthy, term neonates in the first week of life, undergoing heel prick for routine screening were randomized to receive a heel prick in either the drowsy/sleeping state or the awake (but not fussy or crying) state. 48 babies in sleeping or drowsy states and 47 in the awake state...
journal_title:Indian pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s13312-011-0082-1
更新日期:2011-05-01 00:00:00
abstract:BACKGROUND:Data on blood pressure recorded by oscillometric method is limited. OBJECTIVE:To develop simplified tables and charts of blood pressure recorded by oscillometric method in children. DESIGN:Cross-sectional. SETTING:Ballabhgarh, Haryana. PARTICIPANTS:Healthy school-children. MAIN OUTCOME MEASURES:Blood pr...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-015-0749-0
更新日期:2015-11-01 00:00:00
abstract::A 13-year old girl presented with a decade long anemia, diffuse alveolar hemorrhage and interstistial lung disease; was eventually diagnosed as ANCA associated vasculitis. High index of suspicion is thus warranted for alternative diagnosis in chronic anemia, despite increased prevalence of infectious diseases and nutr...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-013-0042-z
更新日期:2013-02-01 00:00:00
abstract::Acute interstitial nephritis (AIN) should be ruled out in children with unexplained acute renal failure. We present a 4 1/2 year old girl who presented with oliguric acute renal failure preceded by a febrile illness. Renal histopathology revealed features of drug induced AIN. She recovered with dialysis, other support...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2003-04-01 00:00:00
abstract::Berardinelli-Seip congenital lipodystrophy (BSCL) is a very rare genetic disorder characterized by lipoatrophy, hypertriglyceridemia, hepatomegaly and acromegaloid features. On the basis of mutational and haplotype analysis, BSCL families have been classified into three types BSCL 1, BSCL2 and BSCLX. We report Berardi...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2006-05-01 00:00:00
abstract:Context:Infantile colic is self-limiting condition but it can be a cause of anxiety for parents and challenge for doctors. The challenge for the doctors lies in correct identification of the condition and appropriate management. The objective of this review article is to summarize the pathophysiology, treatment options...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:2018-11-15 00:00:00
abstract::Informed consent is a communication process of providing the patient/parents/guardians with relevant information regarding the treatment and the diagnosis, so that they can make informed decisions. The process of informed consent in pediatric patients is not well understood. The amount of information to be disclosed i...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s13312-010-0173-4
更新日期:2010-12-01 00:00:00
abstract::Pediatric coronavirus disease-19 (COVID-19) infection is relatively mild when compared to adults, and children are reported to have a better prognosis. Mortality in children appears rare. Clinical features of COVID-19 in children include fever and cough, but a large proportion of infected children appears to be asympt...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:2020-05-15 00:00:00
abstract::Indian Pediatrics limited the number of authorship to 5, 4 and 2 for Brief Reports (BR), Case Reports (CR), and Letters to the Editor (LE), respectively from January 2003, to curb gift authorship. To analyze the impact of this policy, a comparative analysis was conducted for years 2002-2004. Mean (SD) number of author...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract::The present study was undertaken to find out the best simple anthropometric parameter for identifying low birth weight babies (LBW). A total of 1000 newborn babies were subjected to anthropometry within 48 hours of life. Birth weight was significantly correlated (p less than 0.001) with thigh circumference (TC), mid-a...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:Inflammatory pseudo tumor, a rare non-neoplastic lesion, commonly presents as slow growing solid lesion in the lung, but many extra-pulmonary locations have been described. CASE CHARACTERISTICS:A 4-year-old girl who presented with respiratory distress due to massive pleural effusion. Computed tomography rev...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2018-04-15 00:00:00
abstract::Sixty children with acute bacterial meningitis (ABM) were prospectively studied for their serum sodium values and cerebrospinal fluid (CSF), serum and urinary osmolality. The results have been compared with 20 age and nutritionally matched controls. Even though mean serum osmolality (283.2 +/- 13.84 mOsm/kg) and serum...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1993-10-01 00:00:00
abstract:OBJECTIVE:To assess the glycometabolic function in chronically transfused patients of beta- thalassemia major in terms of glucose tolerance, insulin secretion, insulin resistance index, and beta cell function index and to determine their relationship with clinical and biochemical profile. METHODS:30 homozygous thalass...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2006-05-01 00:00:00
abstract::In this study, 78 middle ear aspiration samples from 59 children between the ages of 2 14 who have undergone myringotomy under general anesthesia were included. The presence of DNA genome of Chlamydia trachomatis was analyzed with polymerase chain reaction in the aspiration material. The relationship between the natur...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2005-07-01 00:00:00
abstract::Trichotillomania, though uncommon, is one of the causes of unexplained hair loss, especially in children. Three girls in the age group of 4-6 years were observed in our pediatric dermatology clinic to have trichotillomania. In one child, there was co-existent alopecia areata. All were referred to the child guidance cl...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::Bone mineral content (BMC) was determined at the distal radius in 70 children aged 2-14 years; Group I comprising 34 normal healthy children and Group II 36 malnourished children by the method of single photon absorptiometry. The mean value of BMC in Group I was 0.3 +/- 0.04 g/cm in 2-5 year, 0.52 +/- 0.08 g/cm in 6-1...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1993-04-01 00:00:00
abstract::Childhood Hodgkins Disease (HD) is a lymphoma that displays characteristic epidemiological, clinical and pathological features according to various geographic areas, particularly according to the socio-economic level of a given country. India presents a similar sex, age and subtype distribution as other emerging count...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:2006-02-01 00:00:00
abstract::Intravenously administered rehydration therapy was compared with orally administered rehydration therapy for treating children with diarrhea in a clinical study of 3000 children admitted to the Medical College Hospital, Kottayam, India. Oral rehydration was more effective and safer than intravenously administered flu...
journal_title:Indian pediatrics
pub_type: 临床试验,杂志文章
doi:
更新日期:1978-10-01 00:00:00
abstract:OBJECTIVE:To determine the survival of children =18 y, treated with immunosuppressive therapy (IST) using equine antithymocyte globulin (e-ATG) and cyclosporine (CsA). DESIGN:Prospective data entry as per a specified format. SETTING:Tertiary care hospital. PATIENTS:From January 1998 to December 2009, 40 children wer...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-012-0086-5
更新日期:2012-05-01 00:00:00
abstract:NEED AND PURPOSE OF REVIEW:A number of newer anti-epileptic drugs have been developed in the last few years to improve the treatment outcomes in epilepsy. In this review, we discuss the use of newer anti-epileptic drugs in children. METHODS USED FOR LOCATING, SELECTING, EXTRACTING AND SYNTHESIZING DATA:MEDLINE search ...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s13312-013-0284-9
更新日期:2013-11-08 00:00:00
abstract::Pathologic fractures in children may be due to various causes. Rarely, it may be the presenting symptom of neurofibromatosis. A misdiagnosis of Rickets and Vitamin D supplementation in such a case may wreak havoc in the form of iatrogenic hypervitaminosis D. We report one such case. ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-010-0137-8
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:To evaluate recovery and survival of severely wasted children without community management of acute malnutrition programme. DESIGN:Single time point follow-up (24th December 2013 - 2nd April, 2014) of severely wasted children identified in a community-based cross-sectional survey (September 2012 - October 20...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-017-1142-y
更新日期:2017-10-15 00:00:00
abstract::Testicular adrenal rest tumors (TART) are consequences of delayed diagnosis and/or undertreatment in patients with congenital adrenal hyperplasia (CAH). We describe a case of CAH with TART who presented with bilateral macroorchidism. He was managed with glucocorticoids which led to decrease in testicular size without ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-012-0096-3
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:To assess yield of MECP2 gene sequence variations analysis and large deletions in suspected cases of Rett syndrome. DESIGN:Descriptive study. SETTING:Tertiary-care medical genetics center. PATIENTS:Girls with neuroregression, postnatal microcephaly and signs and symptoms suggestive of classical and atypica...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2018-06-15 00:00:00
abstract::Thrombocytosis is a frequent finding in hemograms obtained from hospitalized and ambulatory children due to the widespread use of automated blood cell counters. Pediatricians are commonly puzzled in cases of thrombocytosis to determine the underlying cause and the need for therapy. The purpose of this review is to ass...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:2008-08-01 00:00:00
abstract::Antimicrobial resistance has become a global menace. As the resistance patterns and numbers are progressively increasing, it has become a major cause of morbidity and mortality in hospitalized patients, especially children. Efforts are being put world-over to curb the rising resistance by various means, especially by ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-016-0839-7
更新日期:2016-04-01 00:00:00