Matrix change of bone grafting substitute after implantation into guinea pig bulla.

Abstract:

BACKGROUND:Many different surgical techniques have been developed to remove open mastoid cavities. In addition to autologous materials, alloplastic substances have been used. A very slow absorption of these materials and extrusion reactions have been reported. We investigated a newly developed, highly porous bone grafting material to eliminate open mastoid cavities, in an animal model. To characterise the transformation process, the early tissue reactions were studied in relation to the matrix transformation of the bone material. MATERIAL AND METHODS:NanoBone (NB), a highly porous bone grafting material based on calcium phosphate and silica, was filled into the open bullae from 20 guinea pigs. The bullae were examined histologically. Energy dispersive X-ray spectroscopy (EDX) was used to investigate the change in the elemental composition at different sampling times. The surface topography of the sections was examined by electron microscopy. RESULTS:After 1 week, periodic acid-Schiffs (PAS) staining demonstrated accumulation of glycogen and proteins, particularly in the border area of the NB particles. After 2 weeks, the particles were evenly coloured after PAS staining. EDX analysis showed a rapid absorption of the silica in the bone grafting material. CONCLUSIONS:NanoBone showed a rapid matrix change after implantation in the bullae of guinea pigs. The absorption of the silica matrix and replacement by PAS-positive substances like glycoproteins and mucopolysaccharides seems to play a decisive role in the degradation processes of NB. This is associated with the good osteoinductive properties of the material.

journal_name

Folia Morphol (Warsz)

journal_title

Folia morphologica

authors

Punke Ch,Zehlicke T,Just T,Holzhüter G,Gerber T,Pau HW

subject

Has Abstract

pub_date

2012-05-01 00:00:00

pages

109-14

issue

2

eissn

0015-5659

issn

1644-3284

journal_volume

71

pub_type

杂志文章
  • The influence of experimental Bacteroides fragilis infection on substance P and somatostatin-immunoreactive neural elements in the porcine ascending colon - a preliminary report.

    abstract::The present study was aimed at disclosing the influence of Bacteroides fragilis (one of the most important bacterial agents causing colitis in children) experimental infection on the expression of substance P (SP) and somatostatin (SOM) in neurons and nerve fibres within the porcine ascending colon. Distinct differenc...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:

    authors: Gonkowski S,Kamińska B,Bossowska A,Korzon M,Landowski P,Majewski M

    更新日期:2003-11-01 00:00:00

  • Lymphocyte subsets in the small intestine of piglets fed with probiotic and zinc: a qualitative and quantitative micro-anatomical study.

    abstract:BACKGROUND:Piglet mortality is a real concern to the pig farmers. The major cause is due to the late maturation of the immune system and dietary changes in post-weaned piglets. The potential role of probiotic and zinc in the stimulation of the immune system is well established. Hence, the present study was undertaken t...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:10.5603/FM.a2020.0148

    authors: Kalita A,Talukdar M,Sarma K,Kalita PC,Barman NN,Roychoudhury P,Kalita G,Choudhary OP,Doley PJ,Debroy S,Keneisenuo K,Sarkar R

    更新日期:2021-01-13 00:00:00

  • Reduced c-Fos expression in orexin neurons of the lateral hypothalamic area and the locus coeruleus following injection of spinosin into mice.

    abstract:BACKGROUND:Spinosin, a major component of Samen Ziziphi spinosae, has been shown to modulate sedation and hypnosis; however, the underlying neuronal mechanisms of its stimulatory effects remain unclear. MATERIALS AND METHODS:In the present study, we injected spinosin (15 mg/kg) or saline into mice, which were killed a...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:10.5603/FM.a2019.0118

    authors: Zhang JP,Liao DQ,Li L,Chu L

    更新日期:2020-01-01 00:00:00

  • An evaluation of Ki-67 and PCNA expression in conjunctival and eyelid tumours.

    abstract::The aim of our study was an evaluation of the expression of cell proliferation markers (PCNA and Ki-67) in conjunctival and eyelid papillomas and squamous and basal cell cancers. A series of 9 cases of squamous cell cancer (SCC), 15 cases of basal cell cancer (BCC) and 43 cases of squamous cell papilloma (SCP) were as...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:

    authors: Reszeć J,Kańczuga-Koda L,Sulkowska M,Koda M,Cylwik J,Barwijuk-Machała M,Sulkowski S

    更新日期:2004-02-01 00:00:00

  • Variations of topography of the parathyroid glands. Clinical aspects.

    abstract::In 120 cadavers four parathyroid glands were found in 56.7% of cases. In most investigated specimens (above 90%) the superior parathyroid glands are localized posteriorly to the recurrent laryngeal nerve, whereas inferior parathyroid glands lie anteriorly to the nerve. The parathyroid glands are localized within a rad...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:

    authors: Lorenc Z,Aleksandrowicz R

    更新日期:1991-01-01 00:00:00

  • Blood vascular organization of the walls of vermiform appendix from human fetus. Examination of vascular corrosion casts in SEM.

    abstract::Ten human vermiform appendices obtained from fetal corpses (160.0-240.0 mm of CRL) were examined using injection-micro corrosion method. Blood vascular bed reproduced with this method was observed with scanning electron microscope (SEM). Blood vascular bed structure of foetal appendix has been described, simultaneousl...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:

    authors: Pityński K,Skawina A,Gorczyca J,Strek P,Nowogrodzka-Zarórska M

    更新日期:1993-01-01 00:00:00

  • Radiomorphometric assessment of the pterygoid hamulus as a factor promoting the pterygoid hamulus bursitis.

    abstract:BACKGROUND:The pterygoid hamulus (PH) is a small protrusion on the base of the pterygoid process of the sphenoid bone. PH is a site of insertion of many muscles and ligaments. Its topography can determine predilection for developing the pterygoid hamulus bursitis (PHB). MATERIALS AND METHODS:The study was conducted ba...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:10.5603/FM.a2019.0049

    authors: Komarnitki I,Skadorwa T,Chloupek A

    更新日期:2020-01-01 00:00:00

  • Light and scanning electron microscopy of the tongue of the sand lizard (Lacerta agilis).

    abstract:BACKGROUND:Despite the fact that numerous reptile species are widely studied by the researchers, information describing the detailed structure of particular organs in many reptiles is missing. MATERIALS AND METHODS:The tongue of the sand lizard (Lacerta agilis) was examined under the light and scanning electron micros...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:10.5603/FM.a2018.0064

    authors: Cizek P,Hamouzova P,Kvapil P,Kyllar M

    更新日期:2019-01-01 00:00:00

  • Septal perforators stemming from a very long left main coronary artery.

    abstract::We report a case of a very long left main coronary artery (58 mm) with septal perforators before bifurcation. The coronary arteries were seen clear of plaques. To the best of our knowledge, this case is very rare because of the existence of the first and second septal perforator arteries originating from a very lon...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:

    authors: Kucukdurmaz Z,Karapinar H,Gul I,Kosar MÍ,Yilmaz A

    更新日期:2012-11-01 00:00:00

  • Partial pancreatic resection along the embryological fusion plane - no longer a fantasy.

    abstract:BACKGROUND:The embryological connection between the dorsal and ventral pancreatic regions divides the pancreas into two segments. This anatomical dependence allows segmental pancreatic resection through the embryological fusion plane (EFP). The advantages of limited pancreatic resection are the preservation of the natu...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:10.5603/FM.a2019.0121

    authors: Łącka M,Łaski D,Hać S,Szymański M

    更新日期:2019-11-21 00:00:00

  • Laryngeal nerve "anastomoses".

    abstract::Laryngeal nerves have been observed to communicate with each other and forma variety of patterns. These communications have been studied extensively and have been of particular interest as it may provide an additional form of innervation to the intrinsic laryngeal muscles. Variations noted in incidence may help explai...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:10.5603/FM.2014.0005

    authors: Naidu L,Lazarus L,Partab P,Satyapal KS

    更新日期:2014-02-01 00:00:00

  • Anatomy of lumbar facet joint: a comprehensive review.

    abstract::Lumbar Facet Joints (LFJs) are diathrodial joints which provide articulation between two adjacent lumbar vertebrae. LFJs represent complex anatomic structures with multifaceted biomechanic and functional characteristics. They are theorized as structures of crucial clinical significance since their degenerative morphol...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:10.5603/FM.a2020.0122

    authors: Kapetanakis S,Gkantsinikoudis N

    更新日期:2020-10-21 00:00:00

  • Dentin dysplasia type I.

    abstract::This paper describes a rare case of genetically determined dentin dysplasia type Iin 26-year-old male patient. The paper highlights anatomical and radiologicalaspects of dental abnormalities and emphasizes the significance of the educationof both general practitioners and paediatricians as regards referring patients w...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:10.5603/FM.a2019.0012

    authors: Kobus A,Świsłocka M,Kierklo A,Borys J,Domel E,Różycki J,Ławicki S,Bagińska J

    更新日期:2019-01-01 00:00:00

  • Morphological classification of the septomarginal trabecula in humans.

    abstract::Although the septomarginal trabecula is a well-known anatomical structure, there continue to be different ways of studying it. In this study, we dissected the muscle bundles that form it, and this has enabled us to present a new classification based on the origin, path, and termination of these bundles. This study was...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:

    authors: Bandeira ST,Wafae GC,Ruiz C,Nascimento SR,Fernandes JR,Wafae N

    更新日期:2011-11-01 00:00:00

  • The orifice of superior thyroid vein to the internal jugular vein in human fetuses.

    abstract::In this study an attempt was made to define the ways of the orifice of the superior thyroid gland to the internal jugular vein in human fetuses, basing on corrosion casts of blood vessels. It was found that most frequently, i.e. in 44% of cases, the superior thyroid gland formed bilaterally multi-level anastomoses wit...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:

    authors: Oszukowski P,Kosiński H

    更新日期:1998-01-01 00:00:00

  • Effects of nicotine administration in rats on MMP2 and VEGF levels in periodontal membrane.

    abstract:BACKGROUND:Nicotine is associated with increased incidence of periodontal disease and poor response to therapy. This article aimed at identifying the expression of matrix metalloproteinases 2 (MMPs2) and vascular endothelial growth factor (VEGF) proteins on extracellular matrix, fibrous distribution and angiogenetic de...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:10.5603/FM.a2018.0004

    authors: Deveci B,Ayna B,Tacir IH,Deveci E,Tuncer MC,Pala A

    更新日期:2018-01-01 00:00:00

  • Anatomic assessment of the left main bifurcation and dynamic bifurcation angles using computed tomography angiography.

    abstract:BACKGROUND:An understanding of the left main coronary artery (LMCA) anatomy is important for accurate diagnosis and therapy. We aimed to investigate LMCA anatomy via 128-multisliced coronary computed-tomography-angiography (CCTA) in patients with normal LMCA. MATERIALS AND METHODS:A total of 201 CCTA studies were incl...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:10.5603/FM.a2016.0059

    authors: Beton O,Kaplanoglu H,Hekimoglu B,Yilmaz MB

    更新日期:2017-01-01 00:00:00

  • Giant cardiac tumours in the newborn: an unusual image.

    abstract::Primary heart tumours in the paediatric population are very rare and they range from 0.01% to 0.04%. Most are benign lesions of which about half are rhabdomyomas. Rhabdomyoma tumour diagnosis is associated with a 75-80% risk of tuberous sclerosis complex (TSC). TSC are characterised with numerous changes of hamartoma-...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:10.5603/FM.a2017.0119

    authors: Kwiatkowska J,Ciemny S,Kozłowski D

    更新日期:2018-01-01 00:00:00

  • Study of the arterial blood supply of the pancreas harvested for transplantation.

    abstract::Blood supply of the pancreas was studied on 42 latex corrosion casts and 22 arteriograms. The study confirmed variability of the arteries of the pancreas especially the dorsal pancreatic artery. ...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:

    authors: Fiedor P,Rezulski J,Wierzbicki Z,Danielewicz R,Michalak G,Wałaszewski J,Nowak M,Rowiński W

    更新日期:1989-01-01 00:00:00

  • Relationship of vascular variations with liver remnant volume in living liver transplant donors.

    abstract:BACKGROUND:In this study, we investigated the relationship between the portal vein and hepatic artery variations and the remaining liver volume in living donors in liver transplantation. MATERIALS AND METHODS:In the study, triphasic abdominal CT images of 180 live liver donor candidates were analyzed retrospectively. ...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:10.5603/FM.a2020.0080

    authors: Yılmaz Çankaya B,Polat G,Aksungur N,Yalçın A,Korkut E,Sade R,Pirimoğlu RB,Kara S,Ay M,Altuntaş N,Alper F

    更新日期:2020-08-04 00:00:00

  • Localisation of NADPH-diaphorase-positive structures in the thymus of the rat, mouse and rabbit.

    abstract::Localisation of the diaphorase activity of nicotinamide adenine dinucleotide phosphate (NADPH-d), acting as a marker of nitric oxide synthesis (NOS), was studied in the thymus of the rat, mouse and rabbit. The NADPH-d-active cells observed in the rat thymus were irregular in shape with numerous projections and were lo...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:

    authors: Svický E,Ondraovic M,Danko J,Ondrasovicová O,Jenca A,Pospieszny N,Toropila M

    更新日期:2003-01-01 00:00:00

  • Coexistence of a pectoralis quartus muscle, a supernumerary head of biceps brachii muscle and an accessory head of flexor digitorum profundus muscle.

    abstract::Although anatomical variations in the upper limb are frequent, coexistence of multiple combined variations is rare. During a routine educational dissection at Jeju National University Medical School, three muscular variations were found in a 75-year-old Korean male cadaver, in which a supraclavicular cephalic vein was...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:10.5603/FM.a2018.0048

    authors: Song H,Kim J,Yoon SP

    更新日期:2019-01-01 00:00:00

  • The paranasal sinuses: three-dimensional reconstruction, photo-realistic imaging, and virtual endoscopy.

    abstract:BACKGROUND:The purpose of the study was to create computer-aided design models of the paranasal sinuses (frontal, maxillary, and sphenoid) and to perform virtual endoscopy (VE) to them by using virtual reality modelling language technique. MATERIALS AND METHODS:The visible human dataset was used as the input imaging d...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:10.5603/FM.a2016.0006

    authors: Kapakin S

    更新日期:2016-01-01 00:00:00

  • Substantia nigra hyperechogenicity in Polish patients with Parkinson's disease.

    abstract:BACKGROUND:Hyperechogenicity of the substantia nigra (SN) measured by transcranial sonography (TCS) is a characteristic feature observed in patients with Parkinson's disease (PD). To our knowledge, no SN hyperechogenicity data are available for Polish population. Moreover most of studies come from few centres, which us...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:10.5603/FM.2014.0042

    authors: Ambrosius W,Michalak S,Owecki M,Łukasik M,Florczak-Wyspiańska J,Kozubski W

    更新日期:2014-08-01 00:00:00

  • Successful combined surgical approach in a rare case of retrotracheal goitre in a patient with anatomical impediments.

    abstract::Diving goitres can descend the cervical region expanding directly into the thoracic cavity. In most cases, diving goitres extend into the anterosuperior compartment, but they may also extend behind the trachea. We herein present a case of a male patient with retrotracheal goitre and history of left thyroid lobectomy a...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:10.5603/FM.a2017.0072

    authors: Spartalis E,Damaskos C,Moris D,Athanasiou A,Spartalis M,Karagkiouzis G,Schizas D,Dimitroulis D,Tomos P

    更新日期:2018-01-01 00:00:00

  • Vascularization of the brain in guinea pig. V. Angioarchitectonics of the thalamus, telencephalon and internal capsule.

    abstract::The main blood supply of the thalamus constitute internal branches of the posterior cerebral, posterior communicating, middle, and choroid arteries. Branches of these arteries from three groups of vessels: medial, lateral, and posterior. Considering the number of vessels, their diameter and direct origin from the cere...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:

    authors: Majewska-Michalska E

    更新日期:1997-01-01 00:00:00

  • Microvascularisation of the scrotal integument of Holstein-Friesian bulls.

    abstract::Based on standard histological methods and specific injection technique, the study demonstrates for the first time the blood vessel system of the scrotal integument.The latter is relatively thin and shows a thick underlying fascia, the tunica dartos. The vessel networks found in both structures are somewhat different ...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:10.5603/fm.2013.0022

    authors: Godynicki S,Meyer W,Jackowiak H,Bollwein H,Pfarrer Ch

    更新日期:2013-05-01 00:00:00

  • Mast cell density, neuronal hypertrophy and nerve growth factor expression in patients with acute appendicitis.

    abstract::In acute appendicitis, although the relationship between the enteric nervous system (ENS) and mast cells (MCs) has been described in a few studies, neither the expression of nerve growth factor (NGF) nor its relation to mast cell density (MCD) and ENS has been delineated yet in this disease. The aim of this study was ...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:

    authors: Coskun N,Sindel M,Elpek GO

    更新日期:2002-01-01 00:00:00

  • Anatomical description of the aortic arch of a rare species "the giant armadillo" (Priodontes maximus; Kerr, 1792).

    abstract::The giant armadillo (Priodontes maximus) is found in diverse habitats from South America. A female adult giant armadillo with a body mass of 45 kg was used. The animal was a victim of trampling on highway AC-40, at 70 km, near the municipality of Capixaba-Acre and the corpse donated to the Animal Anatomy Laboratory at...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:10.5603/FM.a2019.0053

    authors: Santos R,Fernandes M,de Souza SF,Dos Santos-Sousa CA,de Carvalho YK

    更新日期:2020-01-01 00:00:00

  • Facial soft tissue thicknesses in Bulgarian adults: relation to sex, body mass index and bilateral asymmetry.

    abstract:BACKGROUND:The aim of the study is to measure the facial soft tissue thicknesses (STTs) in Bulgarians, to evaluate the relation of the STTs to the nutritional status, sex and bilateral asymmetry, and to examine the correlations between the separate STTs as well as between the STTs and body weight, height, and body mass...

    journal_title:Folia morphologica

    pub_type: 杂志文章

    doi:10.5603/FM.a2017.0114

    authors: Toneva D,Nikolova S,Georgiev I,Harizanov S,Zlatareva D,Hadjidekov V,Lazarov N

    更新日期:2018-01-01 00:00:00