An evaluation of Ki-67 and PCNA expression in conjunctival and eyelid tumours.

Abstract:

:The aim of our study was an evaluation of the expression of cell proliferation markers (PCNA and Ki-67) in conjunctival and eyelid papillomas and squamous and basal cell cancers. A series of 9 cases of squamous cell cancer (SCC), 15 cases of basal cell cancer (BCC) and 43 cases of squamous cell papilloma (SCP) were assessed using the immunohistochemical method with monoclonal antibodies. PCNA overexpression was observed in 100% of SCP, in 88.8% of SCC and in 100% of BCC cases. Ki-67 overexpression was seen in 32.5% of cases of SCP, in 22.2% of SCC and in 66.6% of BCC. The results showed that an evaluation of Ki-67 expression is the most valuable cell proliferation marker.

journal_name

Folia Morphol (Warsz)

journal_title

Folia morphologica

authors

Reszeć J,Kańczuga-Koda L,Sulkowska M,Koda M,Cylwik J,Barwijuk-Machała M,Sulkowski S

keywords:

subject

Has Abstract

pub_date

2004-02-01 00:00:00

pages

95-8

issue

1

eissn

0015-5659

issn

1644-3284

journal_volume

63

pub_type

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