Abstract:
:In acute appendicitis, although the relationship between the enteric nervous system (ENS) and mast cells (MCs) has been described in a few studies, neither the expression of nerve growth factor (NGF) nor its relation to mast cell density (MCD) and ENS has been delineated yet in this disease. The aim of this study was to immunohistochemically investigate the relationship between MCD, nervous system and NGF expression in the appendices of cases with clinically and histopathologically diagnosed acute appendicitis and of normal controls. Twenty-five patients with acute appendicitis and twelve normal controls were included in our study. Mast cell tryptase, PGP 9.5 and anti-NGF immunostained tissue sections were subjected to quantitative image analysis. Our results showed that MCD, the number of Schwann cells, the number and size of ganglia and NGF staining were significantly greater in acute appendicitis than in the control group (p < 0.01). A strong correlation between MCD and NGF staining was detected (r = 0.92) only in cases with acute appendicitis. Similarly MCD was also related to neuronal proliferation and hypertrophy in this group. We failed to detect any relationship between NGF staining and neural components either in the acute appendicitis or control groups. Our findings indicate that mast cells could be one of the important cell populations responsible for nerve proliferation and hypertrophy in acute appendicitis. The relationship between NGF staining and MCD and the lack of correlation between NGF staining and changes in neural components suggest that, in acute appendicitis, NGF might be responsible for the increased number of MCs, but not for neuronal proliferation and hypertrophy.
journal_name
Folia Morphol (Warsz)journal_title
Folia morphologicaauthors
Coskun N,Sindel M,Elpek GOkeywords:
subject
Has Abstractpub_date
2002-01-01 00:00:00pages
237-43issue
4eissn
0015-5659issn
1644-3284journal_volume
61pub_type
杂志文章abstract::Investigations were carried out on 43 serially sectioned human embryos of developmental stages 18 to 23. The homogeneous interzone of the future knee joint is observed in embryos at stage 18. During stage 19 this interzone is differentiated into dense, intensively stained, peripheral parts, which are the primordia of ...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::It was found in sheep that the left cranial vena cava formed by two brachiocephalic veins terminated in coronary sinus together with left azygous vein and great as well middle cardiac veins. The right azygous vein escapes into right atrium. In dog two cranial venae cavae were observed. The right vena cava terminated i...
journal_title:Folia morphologica
pub_type: 杂志文章
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更新日期:1992-01-01 00:00:00
abstract:BACKGROUND:Supraclavicular variations of the cephalic vein (CV) are detected sporadically. A somewhat more common finding is a CV variation with the typical course of the main vessel but with an additional supraclavicular branch, called the jugulocephalic vein (JCV). The aim of the study was to detect supraclavicular C...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:10.5603/FM.a2015.0125
更新日期:2016-01-01 00:00:00
abstract::Mature male rats received encortone in a dose of 1 mg/kg of body mass for 7 days and 30 days. The following changes were observed in the cells of parotid gland of the experimental animals in comparison with the control: a) after 7 days of encortone treatment increase of secretory cells activity appeared in the intensi...
journal_title:Folia morphologica
pub_type: 杂志文章
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更新日期:1992-01-01 00:00:00
abstract::The anterior tibial artery is of great clinical relevance to vascular infrapopliteal surgery. The sources (origins), length and luminal diameter of the anterior tibial artery in 46 men and 30 women with Lerich syndrome were studied by means of radiological and digital methods. The results obtained were described by tw...
journal_title:Folia morphologica
pub_type: 杂志文章
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更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:In this study, we investigated the relationship between the portal vein and hepatic artery variations and the remaining liver volume in living donors in liver transplantation. MATERIALS AND METHODS:In the study, triphasic abdominal CT images of 180 live liver donor candidates were analyzed retrospectively. ...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:10.5603/FM.a2020.0080
更新日期:2020-08-04 00:00:00
abstract::Although the cephalic vein follows a fairly consistent course, numerous variants have been reported. We found a rare anatomical presentation of the cephalic vein in a 43-year-old Korean male cadaver. The cephalic vein had anastomosed with the basilic vein and brachial vein at the level of the elbow, perforated the pec...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:10.5603/FM.a2015.0082
更新日期:2016-01-01 00:00:00
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journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:2004-05-01 00:00:00
abstract::Localisation of the diaphorase activity of nicotinamide adenine dinucleotide phosphate (NADPH-d), acting as a marker of nitric oxide synthesis (NOS), was studied in the thymus of the rat, mouse and rabbit. The NADPH-d-active cells observed in the rat thymus were irregular in shape with numerous projections and were lo...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::Many theories have been suggested in order to explain the aetiology of septal aperture. The influence of genes, the size and shape of ulna processes, joint laxity, bone robusticity, osteoarthritis, and osteoporosis has been discussed; however, the problem has not yet been solved. The aim of the study was to examine th...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:10.5603/FM.2015.0034
更新日期:2015-01-01 00:00:00
abstract::Measurements were made of the femoral shaft/neck angle (CCD angle) in 106 human foetuses, aged from 16 to 38 hbd, using a "FEM-GEO_03" computer program. The values of the CCD angle in the group under examination were: mean = 140.48 degrees, SD = 6.95 degrees, max = 157.90 degrees, min = 113.93 degrees. No significant ...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:2003-11-01 00:00:00
abstract::Although anatomical variations in the upper limb are frequent, coexistence of multiple combined variations is rare. During a routine educational dissection at Jeju National University Medical School, three muscular variations were found in a 75-year-old Korean male cadaver, in which a supraclavicular cephalic vein was...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:10.5603/FM.a2018.0048
更新日期:2019-01-01 00:00:00
abstract::The cochlear ganglion was investigated in serially sectioned human embryos at developmental stages 18 and 19 (44-46 postovulatory days). During this period the cochlear ganglion is separated from the vestibular ganglion, and it is adjacent to the cochlear duct. In embryos of investigated stages fibers of the cochlear ...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::Diving goitres can descend the cervical region expanding directly into the thoracic cavity. In most cases, diving goitres extend into the anterosuperior compartment, but they may also extend behind the trachea. We herein present a case of a male patient with retrotracheal goitre and history of left thyroid lobectomy a...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:10.5603/FM.a2017.0072
更新日期:2018-01-01 00:00:00
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journal_title:Folia morphologica
pub_type: 杂志文章
doi:10.5603/FM.a2020.0116
更新日期:2020-09-23 00:00:00
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journal_title:Folia morphologica
pub_type: 杂志文章
doi:10.5603/FM.a2020.0035
更新日期:2020-03-24 00:00:00
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journal_title:Folia morphologica
pub_type: 杂志文章
doi:10.5603/FM.a2016.0059
更新日期:2017-01-01 00:00:00
abstract::A study was performed on 12 human embryos at developmental stages 16 and 17 (6(th) week). In the investigated embryos the primary palate is formed from medial nasal, lateral nasal, and maxillary processes. The medial and lateral nasal processes merge and form the nasal fin at stage 16. This fin regresses and at stage ...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:2011-02-01 00:00:00
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journal_title:Folia morphologica
pub_type: 杂志文章
doi:10.5603/FM.a2019.0005
更新日期:2019-01-01 00:00:00
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journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::A rare variation was found in one of the two left renal veins in a 94-year-old male cadaver undergoing routine dissection. The characteristic findings in the cadaver included, in addition to the primary left renal vein, the presence of a posterior left renal vein draining to the left ascending lumbar vein without comm...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:10.5603/FM.2015.0121
更新日期:2015-01-01 00:00:00
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journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::Ten human vermiform appendices obtained from fetal corpses (160.0-240.0 mm of CRL) were examined using injection-micro corrosion method. Blood vascular bed reproduced with this method was observed with scanning electron microscope (SEM). Blood vascular bed structure of foetal appendix has been described, simultaneousl...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::Although the septomarginal trabecula is a well-known anatomical structure, there continue to be different ways of studying it. In this study, we dissected the muscle bundles that form it, and this has enabled us to present a new classification based on the origin, path, and termination of these bundles. This study was...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:2011-11-01 00:00:00
abstract::Normally the 7th cervical vertebra (C7) has a long non-bifid spine. A bifid spine is a feature of typical cervical vertebrae such as C3--C6. In contrast to past studies, which have described a bifid spine in the C3--C6 cervical vertebrae, this study is a report on the presence of a duplicated spinous process in the C7...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:2005-05-01 00:00:00
abstract::Oligodendrocytes, called oligodendroglia, are present in the white and grey substance of the CNS. They constitute a heterogeneous group, in which 3 types of these cells have been distinguished: those of light, medium and dark cytoplasm. They locate themselves at the neurones and blood vessels. The number of light olig...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract::Pain accompanies most of illnesses. Pain results in from activation of a specific sensory system and is not direct result of an illness. Pain system may be activated early in the fetal development before its projections will penetrate the frontal cortex. Therefore, painful experience may induce some physiological cons...
journal_title:Folia morphologica
pub_type: 杂志文章,评审
doi:
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:The left ventricular (LV) hypertrophy increases the risk of heart failure. Hypertension and infiltrative cardiomyopathies are the well-known reasons of LV hypertrophy. The growing interest of scientists in this issue affects hereditary haemochromatosis (HH), which is characterised by the excess deposition of...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:10.5603/FM.a2019.0025
更新日期:2019-01-01 00:00:00
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journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
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journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:2012-02-01 00:00:00