Abstract:
:In this study, the rumen was assessed for its potential to detoxify RDX using molecular microbial ecology as well as analytical chemistry techniques. Results indicated significant loss (P < 0.05) of RDX in <8-h post incubation, and qualitative LC-MS/MS analysis showed evidence for the formation of 1-NO-RDX (M-O + HCOO) and methylenedinitramine metabolites. A total of 1106 16S rRNA-V3 clones were sequenced, and most sequences associated with either the phyla Bacteroidetes or Firmicutes. A LibCompare analysis for the RDX treatment showed an enrichment (P < 0.01) of the genus Prevotella. From these results, it can be concluded that the rumen is capable of detoxifying RDX, and the members of the genus Prevotella are linked to this detoxification.
journal_name
Curr Microbioljournal_title
Current microbiologyauthors
Perumbakkam S,Craig AMdoi
10.1007/s00284-012-0144-1subject
Has Abstractpub_date
2012-08-01 00:00:00pages
195-201issue
2eissn
0343-8651issn
1432-0991journal_volume
65pub_type
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