Abstract:
INTRODUCTION:To investigate the potential correlation of the apparent diffusion coefficient assessed by diffusion-weighted MRI (DWI) and glucose metabolism determined by the standardized uptake value (SUV) at 18F-FDG PET/CT in non-small cell lung cancer (NSCLC). MATERIALS AND METHODS:18F-FDG PET/CT and DWI (TR/TE, 2000/66 ms; b-values, 0 and 500 s/mm(2)) were performed in 41 consecutive patients with histologically verified NSCLC. Analysing the PET-CT data calculation of the mean (SUV(mean)) and maximum (SUV(max)) SUV was performed. By placing a region-of-interest (ROI) encovering the entire tumor mean (ADC(mean)) and minimum ADC (ADC(min)) were determined by two independent radiologists. Results of 18F-FDG PET-CT and DWI were compared on a per-patient basis. For statistical analysis Pearson's correlation coefficient, Bland-Altman and regression analysis were assessed. RESULTS:Data analysis revealed a significant inverse correlation of the ADC(min) and SUV(max) (r=-0.46; p=0.032). Testing the correlation of the ADC(min) and SUV(max) for each histological subtype separately revealed that the inverse correlation was good for both adenocarcinomas (r=-0.47; p=0.03) and squamouscell carcinomas (r=-0.71; p=0.002), respectively. No significant correlation was found for the comparison of ADC(min) and SUV(mean) (r=-0.29; p=0.27), ADC(mean) vs. SUV(mean) (r=-0.28; p=0.31) or ADC(mean) vs. SUV(max) (r=-0.33; p=0.23). The κ-value of 0.88 indicated a good agreement between both observers. CONCLUSION:This preliminary study is the first to verify the relation between the SUV and the ADC in NSCLC. The significant inverse correlation of these two quantitative imaging approaches points out the association of metabolic activity and tumor cellularity. Therefore, DWI with ADC measurement might represent a new prognostic marker in NSCLC.
journal_name
Eur J Radioljournal_title
European journal of radiologyauthors
Regier M,Derlin T,Schwarz D,Laqmani A,Henes FO,Groth M,Buhk JH,Kooijman H,Adam Gdoi
10.1016/j.ejrad.2011.11.050subject
Has Abstractpub_date
2012-10-01 00:00:00pages
2913-8issue
10eissn
0720-048Xissn
1872-7727pii
S0720-048X(11)00828-Xjournal_volume
81pub_type
杂志文章abstract:PURPOSE:To perform a systematic review and meta-analysis evaluating usefulness of high-risk CT features (HRFs) on follow-up CT in detecting local recurrence after stereotactic body radiation therapy (SBRT) in lung cancer patients. METHODS:Pubmed and EMBASE were searched up to January 11th, 2019. We included studies th...
journal_title:European journal of radiology
pub_type: 杂志文章,meta分析
doi:10.1016/j.ejrad.2020.108978
更新日期:2020-06-01 00:00:00
abstract:PURPOSE:To compare low- and high-attenuation oral contrast media for depiction of normal gastrointestinal anatomy with multidetector-row computed tomography (MDCT). MATERIALS AND METHODS:A prospective, randomized study of 90 consecutive patients without known or suspected gastrointestinal disease was conducted after t...
journal_title:European journal of radiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ejrad.2007.05.015
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:Velocity-encoding is used to quantify tricuspid regurgitation (TR) by cardiovascular magnetic resonance (CMR), but requires additional dedicated imaging. We hypothesized that size and signal intensity (SI) of the cross-sectional TR jet area in the right atrium in short-axis steady-state free-precession image...
journal_title:European journal of radiology
pub_type: 杂志文章
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更新日期:2017-01-01 00:00:00
abstract:AIM:The objective of this study is to evaluate the efficacy and safety of image-guided percutaneous splenic interventions as diagnostic or therapeutic procedures. MATERIALS AND METHODS:We performed a retrospective review of our interventional records from July 2001 to June 2006. Ninety-five image-guided percutaneous s...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2007.02.011
更新日期:2007-10-01 00:00:00
abstract::There are many potential challenges to developing a high quality, efficient CT colonography service. Some are clear and predictable, for example creating CT capacity and securing financial resources, but some are less obvious, such as harnessing local support or changing referral practice amongst clinical colleagues. ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2012.03.018
更新日期:2013-08-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2008.01.049
更新日期:2009-05-01 00:00:00
abstract:OBJECTIVES:To determine the value of computer-aided detection (CAD) for solid pulmonary nodules in ultralow radiation dose single-energy computed tomography (CT) of the chest using third-generation dual-source CT at 100kV and fixed tube current at 70 mAs with tin filtration. METHODS:202 consecutive patients undergoing...
journal_title:European journal of radiology
pub_type: 临床试验,杂志文章
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abstract:OBJECTIVE:To assess the diagnostic accuracy of multi-detector-row computed tomography (MDCT) for the detection of ampullary adenomas or adenocarcinomas in situ. MATERIALS AND METHODS:We retrospectively reviewed 21 computed tomography (CT) images from 20 patients with ampullary tumors, and 22 CT images from 22 patients...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2010.10.022
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journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2009.09.008
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abstract:OBJECTIVE:To assess virtual non-enhanced dual energy computed tomography (DECT) reconstruction as a potential alternative to true non-enhanced thoracic and abdominal CT scans in patients with suspected active hemorrhage. METHODS AND MATERIALS:Ninety-seven consecutive patients with suspected active bleeding, who underw...
journal_title:European journal of radiology
pub_type: 杂志文章
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更新日期:2018-12-01 00:00:00
abstract:PURPOSE:Currently, clinical research approaches are sparse in molecular imaging studies. Moreover, possible links between imaging features and pathological laboratory parameters are unknown, so far. Therefore, the goal was to find a possible relationship between imaging features and peripheral blood cell apoptosis, and...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2010.08.030
更新日期:2011-09-01 00:00:00
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doi:10.1016/j.ejrad.2021.109522
更新日期:2021-01-06 00:00:00
abstract:PURPOSE:Run-off Computed Tomography Angiography (run-off CTA) of the lower extremities has become the method of choice for the diagnostic imaging of patients suffering from peripheral arterial disease (PAD). However, it remains a challenging radiological examination with a considerable risk of non-diagnostic image qual...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2018.11.030
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:The purpose of this retrospective study was to determine what gives rise to the periportal free air, and ligamentum teres and falciform ligament signs on CT in patients with gastrointestinal (GI) tract perforation, and whether these specific air distributions can play a clinically meaningful role in the diagnos...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2009.07.033
更新日期:2011-02-01 00:00:00
abstract::Light food diet and low residual diet with hydration, both combined with Proctosal and Bisacodyl cleansing, were compared in 268 patients in the preparation of the colon for double contrast examination. Low residual diet with hydration resulted in significantly less residual fecal material, no flocculation of the bari...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:
更新日期:1983-08-01 00:00:00
abstract:PURPOSE:To assess the relationship between imaging follow-up and all-cause mortality in subjects ≥65 years with and without incidental pancreatic cysts (IPC). METHODS AND MATERIALS:Patients ≥65 years with abdominal CT/MR 11/1/01-11/1/11 were included. IPC group included subjects with IPC on CT/MR report; No-IPC group ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2016.03.008
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:To investigate the distribution of an ultrasound-guided intra-articular (IA) injection in the wrist joint of patients with rheumatoid arthritis (RA). METHODS:An ultrasound-guided IA drug injection into the wrist joint was performed in 17 patients with 1 ml methylprednisolone (40 mg/ml), 0.5 ml Lidocaine (5mg...
journal_title:European journal of radiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ejrad.2007.08.037
更新日期:2009-02-01 00:00:00
abstract::Automatic computer-assisted detection (auto-CAD) of significant coronary artery disease (CAD) in coronary computed tomography angiography (cCTA) has been shown to have relatively high accuracy. However, to date, scarce data are available regarding the performance of auto-CAD in the setting of acute chest pain. This st...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2012.01.017
更新日期:2012-04-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章
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journal_title:European journal of radiology
pub_type: 杂志文章
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更新日期:1989-11-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章
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更新日期:2021-02-01 00:00:00
abstract::Chiari III malformation is an extremely rare condition, and is characterized by the hindbrain herniation into a low occipital or high cervical encephalocele together with the pathologic and imaging features of the Chiari II malformation. In this report, an unusual variant of the Chiari III malformation was diagnosed i...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/s0720-048x(01)00334-5
更新日期:2001-09-01 00:00:00
abstract:PURPOSE:To correlate dynamic MRI assays of macromolecular endothelial permeability with microscopic area-density measurements of vascular endothelial growth factor (VEGF) in tumors. METHODS AND MATERIAL:This study compared tumor xenografts from two different human cancer cell lines, MDA-MB-231 tumors (n=5), and MDA-MB...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2011.07.016
更新日期:2012-05-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2003.08.006
更新日期:2004-06-01 00:00:00
abstract:OBJECTIVES:To retrospectively evaluate the effects of a speckle reduction algorithm on radiologists' diagnosis of malignant and benign breast lesions on ultrasound (US) images. METHODS:Using a database of 603 breast (US) images of 211 cases (109 benign lesions and 102 malignant ones), the original and speckle-reduced ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2009.10.001
更新日期:2010-07-01 00:00:00
abstract:INTRODUCTION:Computed tomography (CT) is a widespread and highly precise technique working in the energy range around 50-100 keV. For radiotherapy, however, the MeV energy range enables a better dose distribution. This gap between diagnosis and therapy can be overcome by the use of a modified CT machine in combination ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2008.04.040
更新日期:2008-12-01 00:00:00
abstract::Computed tomography (CT) is considered to be the gold standard method for the assessment of morphological changes in the pulmonary parenchyma. Although its spatial resolution is lower than that of CT, MRI offers the advantage of characterizing different aspects of tissue based on the degree of contrast on T1-weighted ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2013.04.037
更新日期:2013-09-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/s0720-048x(02)00052-9
更新日期:2003-02-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2015.05.005
更新日期:2015-08-01 00:00:00