Multi-parametric quantification of tricuspid regurgitation using cardiovascular magnetic resonance: A comparison to echocardiography.

Abstract:

BACKGROUND:Velocity-encoding is used to quantify tricuspid regurgitation (TR) by cardiovascular magnetic resonance (CMR), but requires additional dedicated imaging. We hypothesized that size and signal intensity (SI) of the cross-sectional TR jet area in the right atrium in short-axis steady-state free-precession images could be used to assess TR severity. METHODS:We studied 61 patients with TR, who underwent CMR and echocardiography within 24h. TR severity was determined by vena contracta: severe (N=20), moderate or mild (N=41). CMR TR jet area and normalized SI were measured in the plane and frame that depicted maximum area. ROC analysis was performed in 21/61 patients to determine diagnostic accuracy of differentiating degrees of TR. Optimal cutoffs were independently tested in the remaining 40 patients. RESULTS:Measurable regions of signal loss depicting TR jets were noted in 51/61 patients, while 9/10 remaining patients had mild TR by echocardiography. With increasing TR severity, jet area significantly increased (15±14 to 38±20mm2), while normalized SI decreased (57±27 to 23±11). ROC analysis showed high AUC values in the derivation group and good accuracy in the test group. CONCLUSION:TR can be quantified from short-axis CMR images in agreement with echocardiography, while circumventing additional image acquisition.

journal_name

Eur J Radiol

authors

Medvedofsky D,León Jiménez J,Addetia K,Singh A,Lang RM,Mor-Avi V,Patel AR

doi

10.1016/j.ejrad.2016.11.025

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

213-220

eissn

0720-048X

issn

1872-7727

pii

S0720-048X(16)30376-X

journal_volume

86

pub_type

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