Abstract：
OBJECTIVES:To prospectively compare the diagnostic efficacy of conventional diffusion-weighted imaging (DWI) and diffusion kurtosis imaging (DKI) in differentiating between muscle-invasive bladder cancer (MIBC) and non-muscle-invasive bladder cancer (NMIBC). METHODS:Multiple b value DWIs were performed using a 3-T magnetic resonance (MR) imaging unit in fifty-one patients with bladder cancer including MIBC and NMIBC confirmed by histopathological findings. DWI data were postprocessed using mono-exponential and DKI models to calculate the apparent diffusion coefficient (ADC), apparent diffusional kurtosis (Kapp), and kurtosis-corrected diffusion coefficient (Dapp). Receiver-operating characteristic (ROC) analysis was performed to compare the diagnostic efficacy of all diffusion parameters. RESULTS:All parameters differed significantly between MIBC and NIMBC including increased Kapp, decreased Dapp and ADC (all p < 0.001). Only the combination of Dapp and Kapp was significantly higher than ADC (p < 0.05), whilst Dapp and Kapp were not statistically different from ADC. CONCLUSIONS:Both conventional DWI and DKI models are beneficial in differentiating between MIBC and NMIBC, whilst the combination of Dapp and Kapp can produce a more robust value than conventional ADC value in evaluating aggressiveness of bladder cancer.
journal_name
Eur J Radioljournal_title
European journal of radiologyauthors
Li Q,Cao B,Tan Q,Liu K,Jiang S,Zhou Jdoi
10.1016/j.ejrad.2021.109522subject
Has Abstractpub_date
2021-01-06 00:00:00pages
109522eissn
0720-048Xissn
1872-7727pii
S0720-048X(21)00002-4journal_volume
136pub_type
杂志文章abstract：PURPOSE:British Thoracic Society (BTS) guidelines advocate using FDG PET-CT with the Herder model to estimate malignancy risk in solitary pulmonary nodules (SPNs). Qualitative and semi-quantitative assessment of SPN uptake is based upon analysis of Ordered Subset Expected Maximisation (OSEM) PET images. Our aim was to ...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2019.06.005
更新日期：2019-08-01 00:00:00
abstract：:This is a retrospective study of a series of seven patients with pancreatic metastases studied by ultrasonography and computed tomography. They were detected during tumor staging, or in the follow-up period of over 10 years of patients with advanced known malignancy. Lesions were multiple in two patients and solitary ...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/0720-048x(91)90131-e
更新日期：1991-01-01 00:00:00
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journal_title：European journal of radiology
pub_type： 杂志文章,评审
doi：10.1016/j.ejrad.2005.03.016
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journal_title：European journal of radiology
pub_type： 临床试验,杂志文章
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abstract：:Rapid advancements in multidetector row computed tomography (MDCT) are beginning to revolutionise cardiac imaging applications. As a consequence, coronary CT angiography (CTA) is fast emerging as a highly effective, noninvasive imaging technique for the assessment of coronary artery disease (CAD). Technology is improv...
journal_title：European journal of radiology
pub_type： 杂志文章,评审
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abstract：OBJECTIVES:To assess the diagnostic performance of whole-body magnetic resonance imaging (WB-MRI) by diffusion-weighted whole-body imaging with background body signal suppression (DWIBS) in malignant tumor detection and the potential diagnostic advantages in generating fused DWIBS/3D-contrast enhanced T1w (3D-CE-T1w) i...
journal_title：European journal of radiology
pub_type： 杂志文章
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journal_title：European journal of radiology
pub_type： 杂志文章,评审
doi：10.1016/j.ejrad.2004.07.022
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journal_title：European journal of radiology
pub_type： 杂志文章,评审
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journal_title：European journal of radiology
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journal_title：European journal of radiology
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journal_title：European journal of radiology
pub_type： 杂志文章,评审
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更新日期：2013-05-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Evaluation of bone marrow infiltration is an essential step in the staging of lymphoma. The accuracy of (18)F-fluorodeoxyglucose-positron emission tomography ((18)F-FDG PET), combined (18)F-fluorodeoxyglucose-positron emission tomography/computed tomography ((18)F-FDG-PET/CT) and magnetic resonan...
journal_title：European journal of radiology
pub_type： 杂志文章,meta分析,评审
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更新日期：2012-02-01 00:00:00
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journal_title：European journal of radiology
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journal_title：European journal of radiology
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更新日期：2012-11-01 00:00:00
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journal_title：European journal of radiology
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更新日期：2011-12-01 00:00:00
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journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2014.11.035
更新日期：2015-04-01 00:00:00
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journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2007.09.035
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journal_title：European journal of radiology
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journal_title：European journal of radiology
pub_type： 杂志文章,评审
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journal_title：European journal of radiology
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journal_title：European journal of radiology
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更新日期：2007-03-01 00:00:00
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journal_title：European journal of radiology
pub_type： 杂志文章
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更新日期：1993-09-01 00:00:00
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journal_title：European journal of radiology
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journal_title：European journal of radiology
pub_type： 杂志文章
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更新日期：2018-02-01 00:00:00
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journal_title：European journal of radiology
pub_type： 杂志文章
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更新日期：2021-02-01 00:00:00
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journal_title：European journal of radiology
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journal_title：European journal of radiology
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journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/s0720-048x(99)00086-8
更新日期：1999-08-01 00:00:00
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journal_title：European journal of radiology
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更新日期：2020-05-01 00:00:00
