Abstract:
OBJECTIVE:Hypothyroidism is a common complication in patients receiving tyrosine kinase inhibitors. We evaluated the relationship between thyroid size evident on CT and thyroid function in patients with advanced renal cell carcinoma (RCC) receiving tyrosine kinase inhibitors. MATERIALS AND METHODS:Forty-two patients with metastatic RCC receiving tyrosine kinase inhibitors (sorafenib n=25; sunitinib n=17) and, followed-up for ≥12 months were eligible. Patients who had ever shown an elevated thyroid-stimulating hormone (TSH) level of >10 mU/l were defined as having "hypothyroidism". CT scans were performed before, and 3, 6, 9, and 12 months after the start of treatment. The area of the thyroid in the maximum section at each examination was measured and compared with that before treatment. Using repeated-measures ANOVA, differences in thyroid size were compared over time between patients with and without "hypothyroidism", in relation to the type of drug employed. RESULTS:Twenty-one patients (sorafenib 9, sunitinib 12) developed "hypothyroidism" 95±88 days (range 12-315 days) after the start of treatment. In such patients, the thyroid was reduced in size to 89±16% after 3 months, 81±21% after 6 months, 71±21% after 9 months and 68±21% after 12 months, whereas the patients without "hypothyroidism" maintained a thyroid size of 90±12% even after 12 months (p=0.0030). Among the patients with "hypothyroidism", those treated with sunitinib tended to show greater thyroid size reduction than those with sorafenib (59±23% vs. 79±13%, after 12 months). CONCLUSION:Tyrosine kinase inhibitors cause an apparent thyroid size reduction in patients with "hypothyroidism".
journal_name
Eur J Radioljournal_title
European journal of radiologyauthors
Kitajima K,Takahashi S,Maeda T,Yoshikawa T,Ohno Y,Fujii M,Miyake H,Fujisawa M,Sugimura Kdoi
10.1016/j.ejrad.2011.06.035subject
Has Abstractpub_date
2012-09-01 00:00:00pages
2060-5issue
9eissn
0720-048Xissn
1872-7727pii
S0720-048X(11)00576-6journal_volume
81pub_type
杂志文章abstract::The ability of PI measurements to differentiate between acute rejection and ATN was investigated in 37 patients, who were frequently examined by duplex Doppler after kidney transplant. Absolute PI values as well as increase in PI were recorded and the clinical course was correlated with these pulsatility measurements....
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/0720-048x(92)90057-g
更新日期:1992-01-01 00:00:00
abstract::The pulmonary vasculature and its role in perfusion and gas exchange is an important consideration in many conditions of the lung and heart. Currently the mainstay of imaging of the vasculature and perfusion of the lungs lies with CT and nuclear medicine perfusion scans, both of which require ionizing radiation exposu...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/j.ejrad.2016.10.003
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:To compare outcomes after imaging-guided transforaminal lumbar nerve root blocks in MRI confirmed symptomatic disc herniation patients with and without Modic changes (MC). METHODS:Consecutive adult patients with MRI confirmed symptomatic lumbar disc herniations and an imaging-guided lumbar nerve root block i...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2014.06.008
更新日期:2014-10-01 00:00:00
abstract:PURPOSE:the purpose of this study was to evaluate defect width of patellar tendon after harvest for anterior cruciate ligament reconstruction. MATERIALS AND METHODS:we performed MRI at various time interval after graft harvest (2-96 months) on 28 patients who had had reconstruction of the anterior cruciate ligament us...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2003.08.006
更新日期:2004-06-01 00:00:00
abstract::Hepatic capsular retraction is a morphologic descriptor that refers to invagination or focal flattening of the typical smooth contour of the liver capsule. It is an uncommon finding that, when combined with other imaging features and clinical context, can help to refine the differential diagnosis in patients with live...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/j.ejrad.2019.01.037
更新日期:2019-04-01 00:00:00
abstract:PURPOSE:To retrospectively evaluate agreement between modified RECIST (mRECIST) assessed at Computed Tomography (CT) and pathology in a large series of patients with hepatocellular carcinoma (HCC) who were transplanted after transarterial chemoembolization (TACE). MATERIALS AND METHODS:IRB approval was obtained. The s...
journal_title:European journal of radiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ejrad.2012.12.009
更新日期:2013-05-01 00:00:00
abstract::Identification of abnormal bile related to various pathological processes in the pancreaticobiliary tract can be important in the diagnosis of disease and the determination of appropriate treatment. Magnetic resonance (MR) imaging can allow comprehensive evaluation of abnormal bile because MR usually provides better t...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2009.05.050
更新日期:2010-11-01 00:00:00
abstract:OBJECTIVE:The aim of our study was to determine the impact of treatment with exogenous surfactant (ES) and high frequency oscillatory ventilation (HFOV) on the radiological appearance and clinical course of hyaline membrane disease (HMD) in new-born infants. MATERIALS AND METHODS:New-born infants (18) (median weight, ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/s0720-048x(97)00153-8
更新日期:1998-10-01 00:00:00
abstract:PURPOSE:To assess the usefulness of amide proton transfer (APT) imaging in differentiating parotid tumors. MATERIAL AND METHODS:We retrospectively analyzed 43 histopathologically proven parotid solid tumors with diameters ≥2 cm. Twenty-one tumors were benign and 12 tumors were malignant. Two-dimensional APT imaging wa...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2020.109047
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVE:To evaluate the ultrasonography (US) features of Alagille syndrome (ALGS), as compared with biliary atresia (BA) or neonatal hepatitis (NH). METHODS:Our study included 23 ALGS, 75 BA and 70 NH patients. The initial US images were retrospectively reviewed for gallbladder (GB) morphology with systemic classifi...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2016.03.023
更新日期:2016-06-01 00:00:00
abstract::Tendon imaging is mainly performed with ultrasonography (US) and magnetic resonance imaging (MRI) and has been improved within the last years because of technical advancements and a better understanding of tendon pathology. Several concepts concerning the etiology and the course of tendon diseases have influenced imag...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/s0720-048x(97)00058-2
更新日期:1997-11-01 00:00:00
abstract:PURPOSE:Major arterial hemorrhage is an uncommon but serious complication of pancreatitis with high morbidity and mortality. Digital subtraction angiography (DSA) has long been the gold standard for the detection of a visceral artery pseudoaneurysm or for the site of active bleeding in patients with pancreatitis. Multi...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2006.02.006
更新日期:2006-08-01 00:00:00
abstract:PURPOSE:This survey was conducted to evaluate the radiation dose delivered to the patients through different CT procedures along with its corresponding risks in Yazd province. METHOD:Data for the five most common procedures were collected from six institutions from September 2017. The effective dose for each patient w...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2020.108932
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:Lymphangioleiomyomatosis (LAM) is characterized by proliferation of smooth muscle tissue that causes bronchial obstruction and secondary cystic destruction of lung parenchyma. The aim of this study was to evaluate the typical distribution of cystic defects in LAM with quantitative volumetric chest computed tomo...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2014.12.019
更新日期:2015-04-01 00:00:00
abstract::The aim of the current study was to compare the diagnostic information obtained from a helical CT examination in low severity cervical spine trauma with that from a lateral CT scout view. We included alert and clinically stable patients, who had suffered acute blunt trauma of low or moderate severity. Their scout imag...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2009.03.024
更新日期:2010-07-01 00:00:00
abstract:PURPOSE:To determine the diagnostic performance of the "central echogenic area" sonographic finding in differentiating papillary carcinomas from benign nodules and to how this finding may be used to improve fine needle aspiration(FNA) technique/utilization. MATERIALS AND METHODS:We retrospectively analyzed ultrasound ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2018.01.029
更新日期:2018-04-01 00:00:00
abstract::To save time and expenses we developed a combined program of local short-term catheter thrombolysis (CTL) in the angiographic laboratory followed by a long-term CTL on the ward if necessary to achieve patency. Out of 66 patients with arterial occlusion in the femoro-popliteal region the occluded segment was re-opened ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:
更新日期:1987-11-01 00:00:00
abstract:PURPOSE:To assess and quantify the prevalence and co-occurence of a sellar floor lowering and empty sella phenomenon in patients with GH (growth hormone)-secreting pituitary adenoma. METHODS:A total number of 159 acromegalic patients were included in this study, as well as two control groups (150 patients with non-GH-...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2018.05.009
更新日期:2018-07-01 00:00:00
abstract::We report a case of fibrolamellar carcinoma presenting in a 26-year old female. The patient had gross ascites at presentation. Imaging studies (ultrasonography and computed tomography) strongly suggested extensive intraperitoneal drop metastases. ...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/s0720-048x(99)00137-0
更新日期:1999-11-01 00:00:00
abstract::Ultrasound contrast agents were originally introduced to enhance the Doppler signals when detecting vessels with low velocity flow or when imaging conditions were sub-optimal. Contrast agents showed additional properties, it was discovered that a parenchymal enhancement phase in the liver followed the enhancement of t...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/j.ejrad.2004.03.022
更新日期:2004-06-01 00:00:00
abstract:BACKGROUND:The diffusion tensor imaging (DTI) parameters of the cervical spinal cord (CSC) changes with age. However, previous studies only examined specific CSC areas. OBJECTIVES:To analyze the DTI parameters in all intervertebral space levels of the whole normal CSC and to study the impact of age on these parameters...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2014.09.010
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:To describe imaging of typical conditions and diseases in the neonatal genito-urinary (GU) tract. METHOD:The use, the applications, and typical findings using standard imaging techniques (e.g., ultrasound, US, voiding cystourethrography, VCUG) are described, with emphasis on technical aspects, indications, a...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/j.ejrad.2006.07.022
更新日期:2006-11-01 00:00:00
abstract::The thoracic inlet is insufficiently investigated by conventional radiographic techniques. CT clearly demonstrates this area free of superimposition. Thorough knowledge of cross sectional anatomy is essential for CT interpretation. There is a wide spectrum of pathology involving the thoracic inlet because its visceral...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:
更新日期:1982-08-01 00:00:00
abstract::A mediastinal mass consisting of haematopoietic tissue and situated in the paravertebral area has been demonstrated in an osteomyelosclerotic patient with diffuse extramedullary haematopoiesis. The internal structure of the mediastinal mass was shown by CT, so a correct diagnosis was made without any invasive procedur...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:
更新日期:1982-08-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to establish the cut-off value of the signal intensity drop on chemical shift magnetic resonance imaging (MRI) with appropriate sensitivity and specificity to differentiate osteoporotic from neoplastic wedging of the spine. PATIENTS AND METHODS:All patients with wedging of ver...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2008.06.019
更新日期:2009-10-01 00:00:00
abstract:INTRODUCTION:Time-resolved contrast-enhanced magnetic resonance (MR) angiography (CEMRA) of the intracranial vasculature has proved its clinical value for the evaluation of cerebral vascular disease in cases where both flow hemodynamics and morphology are important. The purpose of this study was to evaluate a combinati...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2010.04.020
更新日期:2011-11-01 00:00:00
abstract::A total of 7 healthy volunteers and 31 patients have been examined clinically, by MRI, TRS, and biopsy. In those patients with established carcinoma, a CT examination was also performed. For the MRI study, a superconducting MR 2000 imager (Picker International) operated at 0.15 T was used with multiplanar SE and IR se...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:
更新日期:1988-02-01 00:00:00
abstract:OBJECTIVES:Lymphangiography and thoracic duct embolization are established treatments for post-surgical chylothorax. There is only limited experience in their application to treat post-surgical chylous ascites. A multi-center analysis of the technical and clinical success of lymphangiography and lymphatic interventions...
journal_title:European journal of radiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ejrad.2018.10.019
更新日期:2018-12-01 00:00:00
abstract:OBJECTIVE:To estimate a frequency of obstetric anal sphincters defects in women after vaginal delivery. METHODS:The study included 102 women, aged from 16 to 40 years (mean age 28.6 years). 28 women had perineal lacerations of 3rd and 4th degree. 22 women had instrumental delivery. Anal endosonography was performed on...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2009.10.008
更新日期:2011-04-01 00:00:00
abstract::Aspiration of the hip joint in the setting of a potentially infected total hip replacement is occasionally unsuccessful under fluoroscopic guidance because of periarticular heterotopic bone. Of 136 consecutive patients with total hip replacements who were referred to the radiology department for hip aspiration because...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/0720-048x(95)00606-q
更新日期:1995-05-01 00:00:00