Abstract：
BACKGROUND AND PURPOSE:Evaluation of bone marrow infiltration is an essential step in the staging of lymphoma. The accuracy of (18)F-fluorodeoxyglucose-positron emission tomography ((18)F-FDG PET), combined (18)F-fluorodeoxyglucose-positron emission tomography/computed tomography ((18)F-FDG-PET/CT) and magnetic resonance imaging (MRI) in diagnosing bone marrow involvement of lymphoma has never been systematically assessed, and the present systematic review was aimed at this issue. METHODS:MEDLINE, EMBASE, Cochrane library and some other databases, from January 1995 to July 2010, were searched for initial studies. All the studies published in English or Chinese relating to the diagnostic value of (18)F-FDG PET, PET/CT and MRI for patients with bone marrow involvement of lymphoma were collected. We extracted data to calculate sensitivity, specificity, SROC curves and AUC and to test for heterogeneity. The statistic software called "Meta-Disc 1.4" was used for data analysis. RESULT:In 32 included studies, PET/CT had the highest pooled sensitivity, 91.6% (95%CI: 85.1, 95.9) and highest pooled specificity, 90.3% (95%CI: 85.9, 93.7). PET/CT also had the highest pooled DOR, 68.89 (95%CI: 15.88, 298.92). The AUC of PET, PET/CT, and MRI were 0.9430, 0.9505 and 0.8764. There was heterogeneity among studies and no evidence of publication bias. CONCLUSION:PET/CT was a highly sensitive and specific modality in diagnosing patients with bone marrow involvement in lymphoma. Compared with MRI and PET alone, PET/CT can play important roles in the staging of lymphoma.
journal_name
Eur J Radioljournal_title
European journal of radiologyauthors
Wu LM,Chen FY,Jiang XX,Gu HY,Yin Y,Xu JRdoi
10.1016/j.ejrad.2010.11.020subject
Has Abstractpub_date
2012-02-01 00:00:00pages
303-11issue
2eissn
0720-048Xissn
1872-7727pii
S0720-048X(10)00574-7journal_volume
81pub_type
杂志文章,meta分析,评审abstract：PURPOSE:To investigate the pattern of brain volume changes of the brain in patients with type II diabetes mellitus using voxel-based morphometry. MATERIAL AND METHODS:Institutional ethics approval and informed consent were obtained. VBM based on the high resolution three-dimensional T1-weighted fast spoiled gradient r...
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abstract：PURPOSE:Although delayed enhanced CMR has become a reference method for infarct size quantification, there is no ideal method to quantify total infarct size in a routine clinical practice. In a prospective study we compared the performance and post-processing time of a global visual scoring method to standard quantitat...
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pub_type： 杂志文章,评审
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更新日期：2011-12-01 00:00:00
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journal_title：European journal of radiology
pub_type： 杂志文章
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更新日期：1997-05-01 00:00:00
