Irrigation with chlorhexidine to resolve naturally occurring gingivitis. A methodologic study.

Abstract:

:This study compared oral irrigation and rinsing with chlorhexidine (CHX) and placebo in the treatment of naturally occurring chronic gingivitis. 44 subjects with at least 6 interproximal sites which bled on probing were randomly distributed on a double-blind basis into 4 treatment groups, placebo-rinse, CHX-rinse (0.12%), placebo-irrigation and CHX-irrigation (0.06%). A half-mouth was scaled 2 weeks prior to therapy in all groups. Rinses were performed 2 times daily and irrigation was performed once a day by means of an oral irrigator with the tip directed at a right angle to the tooth. Subjects continued with routine oral hygiene without instruction. The active treatment period was 2 months. Parameters were recorded at baseline and at 60 days. At the conclusion, marginal plaque was cultured for predominant microbial types. CHX-rinse (0.12%) and CHX-irrigation (0.06%) significantly reduced (p less than 0.05) plaque. Gingival bleeding decreased by 26% in both scaled and unscaled sites following CHX (0.12%) rinses and by 40% at both types of sites following CHX (0.06%) irrigation. Bleeding was reduced with CHX-irrigation greater (p less than 0.05) than with the placebo-irrigation. The mean log of colony-forming units of Actinomyces species was significantly lower (p less than 0.05) in the CHX (0.12%) rinse and CHX (0.06%) irrigator groups than in the placebo groups. These data therefore indicate that delivery of CHX (0.06%) by an oral irrigator is an effective means of treating naturally occurring gingivitis.

journal_name

J Clin Periodontol

authors

Brownstein CN,Briggs SD,Schweitzer KL,Briner WW,Kornman KS

subject

Has Abstract

pub_date

1990-09-01 00:00:00

pages

588-93

issue

8

eissn

0303-6979

issn

1600-051X

journal_volume

17

pub_type

临床试验,杂志文章,随机对照试验
  • Periodontal therapy by local delivery of tetracycline.

    abstract::The present investigation assessed the feasibility of treating periodontal disease by controlled delivery of antibacterial agents from within periodontal pockets. Tetracycline-filled hollow fibers placed in the gingival sulcus were shown to have a dramatic effect both on the periodontal microflora and clinical manifes...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1979.tb02186.x

    authors: Goodson JM,Haffajee A,Socransky SS

    更新日期:1979-04-01 00:00:00

  • Effect of two different healing times on the mineralization of newly formed bone using a bovine bone substitute in sinus floor augmentation: a randomized, controlled, clinical and histological investigation.

    abstract:PURPOSE:To investigate the amount of the mineralization of a bovine bone substitute material in sinus floor augmentation after healing times of 3 and 6 months. MATERIALS AND METHODS:Fifty-one patients were randomized into two healing time groups and received sinus floor augmentations with a bovine bone material. After...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/jcpe.12466

    authors: Kohal RJ,Gubik S,Strohl C,Stampf S,Bächle M,Hurrle AA,Patzelt SB

    更新日期:2015-11-01 00:00:00

  • Pulsed laser beam effects on gingiva.

    abstract::The effects of CO2 lasers on human gingiva have been evaluated. Pulsed Nd:YAG lasers have only been available for clinical use in dentistry since 1990. This study evaluated the efficacy of a low-power pulsed laser in removing pocket lining epithelium in humans with moderate periodontitis. 24 specimens of gingival tiss...

    journal_title:Journal of clinical periodontology

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1600-051x.1994.tb00735.x

    authors: Gold SI,Vilardi MA

    更新日期:1994-07-01 00:00:00

  • Clinical research activity in periodontal medicine: a systematic mapping of trial registers.

    abstract:AIM:The primary aim of the study was to systematically map registration records on periodontal medicine in clinical trial registers. The secondary aim was to assess the evolution of periodontal medicine in clinical periodontal research as a whole. MATERIAL AND METHODS:We searched all registration records related to pe...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,评审

    doi:10.1111/jcpe.12534

    authors: Monsarrat P,Blaizot A,Kémoun P,Ravaud P,Nabet C,Sixou M,Vergnes JN

    更新日期:2016-05-01 00:00:00

  • No detrimental effect of fibrin glue on the regeneration of intrabony defects. A controlled clinical trial.

    abstract::This controlled clinical trial evaluated the potential of fibrin glue as a biological carrier to locally deliver guided tissue regeneration (GTR) modulators, 2 controlateral, morphologically similar defects were selected in each of 11 patients and randomly assigned to the test (teflon membrane and fibrin glue) and the...

    journal_title:Journal of clinical periodontology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1600-051x.1995.tb00829.x

    authors: Cortellini P,Pini Prato GP,Tonetti MS

    更新日期:1995-09-01 00:00:00

  • Prevalence and simultaneous occurrence of periodontitis and dental caries.

    abstract:AIM:The aim of the study was to evaluate the prevalence and simultaneous occurrence of periodontal disease and dental caries in Finnish adults. MATERIAL AND METHODS:The study was performed as part of the nationally representative Health 2000 Survey. The study population was 5255 subjects aged 30 years and older. Probi...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051X.2010.01620.x

    authors: Mattila PT,Niskanen MC,Vehkalahti MM,Nordblad A,Knuuttila ML

    更新日期:2010-11-01 00:00:00

  • Periodontal parameters around porous-coated dental implants after 3 to 4 years supporting overdentures.

    abstract::In this study, an assessment using modified periodontal indices was done on a group of 48 fully edentulous patients who had each been treated with 3 porous-coated (EndoPore) dental implants and a mandibular overdenture. Parameters assessed included plaque index (PI), sulcular bleeding index (SBI), pocket probing depth...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1996.tb01819.x

    authors: Levy D,Deporter DA,Watson PA,Pilliar RM

    更新日期:1996-06-01 00:00:00

  • Supportive periodontal therapy of furcation sites: non-surgical instrumentation with or without topical doxycycline.

    abstract:OBJECTIVES:Evaluation of the clinical effect of topical subgingival application of doxycycline gel adjunctively to scaling and root planing (SRP) at furcation sites during supportive periodontal therapy (SPT). MATERIAL AND METHODS:In 39 SPT patients exhibiting at least four pockets > or m with bleeding on probing, SRP...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-051X.2009.01414.x

    authors: Dannewitz B,Lippert K,Lang NP,Tonetti MS,Eickholz P

    更新日期:2009-06-01 00:00:00

  • Association between periodontal disease, tooth loss and liver diseases risk.

    abstract:AIM:The purpose of this study is to assess the associations between periodontal disease, tooth loss and liver diseases. MATERIALS AND METHODS:PubMed and Embase databases were utilized to search eligible studies. Odds ratio (OR) with 95% confidence interval (CI) was used as effect size to assess the associations betwee...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/jcpe.13341

    authors: Chen Y,Yang YC,Zhu BL,Wu CC,Lin RF,Zhang X

    更新日期:2020-09-01 00:00:00

  • Risk determinants of periodontal disease--an analysis of the Study of Health in Pomerania (SHIP 0).

    abstract:BACKGROUND:In this study, risk determinants were determined for periodontal disease in the representative population sample (n=3146) of the Study of Health in Pomerania. METHODS:After examining the net random sample (response 69%) and exclusion of edentulous cases and those with missing values, 2595 subjects remained....

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051X.2004.00629.x

    authors: Kocher T,Schwahn C,Gesch D,Bernhardt O,John U,Meisel P,Baelum V

    更新日期:2005-01-01 00:00:00

  • Antineoplastic agents exacerbate periodontal inflammation and aggravate experimental periodontitis.

    abstract:AIM:This study evaluated the effects of 5-fluorouracil (5-FU) and cisplatin (CIS) in healthy periodontal tissues and in the early stages of experimental periodontitis (EP) in rats. METHODS:One hundred and eighty male rats were divided into three groups, which were submitted to the following systemic treatments: physio...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/jcpe.13101

    authors: Gusman DJR,Ervolino E,Theodoro LH,Garcia VG,Nagata MJH,Alves BES,de Araujo NJ,Matheus HR,de Almeida JM

    更新日期:2019-04-01 00:00:00

  • Soluble beta-1,3/1,6-glucan from yeast inhibits experimental periodontal disease in Wistar rats.

    abstract:OBJECTIVE:We have investigated whether a purified immunomodulatory water soluble beta-1,3/1,6-glucan isolated from the cell wall of Bakers yeast, Saccharomyces cerevisiae, would influence the progression of ligature-induced periodontal disease, and to modulate accompanying cytokine and hypothalamic-pituitary-adrenal (H...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051X.2005.00672.x

    authors: Breivik T,Opstad PK,Engstad R,Gundersen G,Gjermo P,Preus H

    更新日期:2005-04-01 00:00:00

  • An imaging routine for assessing the efficacy of instruments used for scaling and root planing.

    abstract::Deposits of dental plaque or calculus are typically quantified using planimetric techniques. However, error is introduced into a quantitative analysis of plaque deposits using these methods, since they require a significant amount of human intervention. The purpose of this study is to describe and validate a computeri...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1992.tb00683.x

    authors: Lozanoff S,Long BA,Singer DL,Deptuch JJ

    更新日期:1992-09-01 00:00:00

  • Black-pigmented Bacteroides species and Actinobacillus actinomycetemcomitans in subgingival plaque of adult Kenyans.

    abstract::A microbiological study was performed of the subgingival plaque on 2 sites in each of 20 adults originating from a rural area 40 km outside Nairobi, Kenya. The recovery rate of B. gingivalis was 70%, of B. intermedius 100% and of A. actinomycetemcomitans 40% of the subjects, and 50%, 90% and 28%, respectively, of the ...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1989.tb01660.x

    authors: Dahlén G,Manji F,Baelum V,Fejerskov O

    更新日期:1989-05-01 00:00:00

  • Osseintegration following treatment of peri-implantitis and replacement of implant components. An experimental study in the dog.

    abstract:AIM:The aim of the present experiment was to study if the quality of the titanium surface is a decisive factor for osseointegration and re-osseointegration. MATERIAL AND METHODS:2 Labrador dogs were used. The mandibular 1st molars and all premolars were removed bilaterally. 3 months later, 1 standard fixture and 3, 2-...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1034/j.1600-051x.2001.028003258.x

    authors: Persson LG,Ericsson I,Berglundh T,Lindhe J

    更新日期:2001-03-01 00:00:00

  • Predictors of tooth loss during long-term periodontal maintenance: a systematic review of observational studies.

    abstract:OBJECTIVE:To systematically assess the factors influencing tooth loss during long-term periodontal maintenance (PM). METHODS:CENTRAL, MEDLINE and EMBASE were searched up to and including September 2009. Studies limited to patients with periodontitis who underwent periodontal therapy and followed a maintenance care pro...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-051X.2010.01587.x

    authors: Chambrone L,Chambrone D,Lima LA,Chambrone LA

    更新日期:2010-07-01 00:00:00

  • Changes in subgingival microbiota during puberty. A 4-year longitudinal study.

    abstract::It was the purpose of the present investigation to monitor the composition of the subgingival microbiota at selected sites in individuals passing through puberty and to correlate observed changes with the development of pubertal maturation. Between the ages of 11 and 14 years, pubertal and skeletal maturation was moni...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1990.tb01054.x

    authors: Gusberti FA,Mombelli A,Lang NP,Minder CE

    更新日期:1990-11-01 00:00:00

  • Increased bone loss and amount of osteoclasts in kinin B1 receptor knockout mice.

    abstract:AIM:The pathophysiology of periodontal diseases involves aspects of immunity and bone remodelling. Considering the role of the kinin B1 receptor (Bdkrb1) in inflammation and healing, the purpose of this study was to evaluate the contribution of Bdkrb1 to the pathogenesis of periodontitis. MATERIAL AND METHODS:We used ...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/jcpe.12097

    authors: Gonçalves-Zillo TO,Pugliese LS,Sales VM,Mori MA,Squaiella-Baptistão CC,Longo-Maugéri IM,Lopes JD,de Oliveira SM,Monteiro AC,Pesquero JB

    更新日期:2013-07-01 00:00:00

  • Periodontal disease as a risk factor for adverse pregnancy outcomes: a prospective cohort study.

    abstract:AIM:The aim of this study was to determine the association between periodontitis and the incidence of preterm birth (PB), low birth weight (LBW) and preterm low birth weight (PLBW) MATERIAL AND METHODS: One thousand and ninety-six women were enrolled. Periodontal data, pregnancy outcome variables and information on oth...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051X.2007.01166.x

    authors: Agueda A,Ramón JM,Manau C,Guerrero A,Echeverría JJ

    更新日期:2008-01-01 00:00:00

  • Association of periodontal disease to anxiety and depression symptoms, and psychosocial stress factors.

    abstract:OBJECTIVE:A cross-sectional study was conducted to investigate if anxiety, depression and hopelessness symptoms are associated with periodontal disease. METHOD:A total of 160 subjects took part in this study. Probing depth and clinical attachment level were recorded at six sites per tooth and the gingival and plaque i...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051X.2004.00538.x

    authors: Solis AC,Lotufo RF,Pannuti CM,Brunheiro EC,Marques AH,Lotufo-Neto F

    更新日期:2004-08-01 00:00:00

  • Periodontal infection as a possible severity factor for rheumatoid arthritis.

    abstract:OBJECTIVE:Clinical effects of periodontal treatment on biochemical and clinical markers of disease severity in rheumatoid arthritis (RA) patients with periodontal disease were evaluated. METHODS:Forty-two patients were assigned to two groups, G1 (n=16) and G2 (n=26). G1 patients were submitted to oral hygiene instruct...

    journal_title:Journal of clinical periodontology

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1600-051X.2005.00689.x

    authors: Ribeiro J,Leão A,Novaes AB

    更新日期:2005-04-01 00:00:00

  • A controlled 6-month clinical trial to study the effects of a stannous fluoride dentifrice on gingivitis.

    abstract:OBJECTIVES:This study was conducted to assess anti-plaque and anti-gingivitis benefits of a stabilized stannous fluoride (SnF(2))/sodium hexametaphosphate (SHMP) dentifrice versus a negative control. MATERIAL AND METHODS:This was a randomized, 6-month, stratified, single-centre, double-blind, parallel group, clinical ...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-051X.2007.01109.x

    authors: Mallatt M,Mankodi S,Bauroth K,Bsoul SA,Bartizek RD,He T

    更新日期:2007-09-01 00:00:00

  • Efficacy of antibiotics to strains of periodontopathogenic bacteria within a single species biofilm - an in vitro study.

    abstract:OBJECTIVES:This study examined differences in the efficacy of antibiotics against a single strain of three periodontal pathogens grown in an artificial biofilm. METHODS:Single species biofilms were established with artificial saliva and one of the following bacterial strains: Actinobacillus actinomycetemcomitans Y4, S...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.0303-6979.2004.00490.x

    authors: Eick S,Seltmann T,Pfister W

    更新日期:2004-05-01 00:00:00

  • Scanning electron microscopy of unused and used manual toothbrushes.

    abstract::A scanning electron microscopic study of the brushing surface of 17 different types of commercial toothbrushes with natural and nylon bristles was conducted on new unused brushes as well as on 65 brushes used from 1 month up to 1 year, once, twice or three times a day, with various brushing techniques. Natural swine o...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1982.tb01231.x

    authors: Massassati A,Frank RM

    更新日期:1982-03-01 00:00:00

  • Mechanical non-surgical treatment of peri-implantitis: a single-blinded randomized longitudinal clinical study. II. Microbiological results.

    abstract:BACKGROUND:Peri-implantitis is common in patients with dental implants. We performed a single-blinded longitudinal randomized study to assess the effects of mechanical debridement on the peri-implant microbiota in peri-implantitis lesions. MATERIALS AND METHODS:An expanded checkerboard DNA-DNA hybridization assay enco...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-051X.2010.01561.x

    authors: Persson GR,Samuelsson E,Lindahl C,Renvert S

    更新日期:2010-06-01 00:00:00

  • Subantimicrobial dose doxycycline as adjunctive treatment for periodontitis. A review.

    abstract:BACKGROUND:Subantimicrobial dose doxycycline (SDD--20 mg doxycycline twice daily) is indicated as an adjunctive treatment for periodontitis. Doxycycline downregulates the activity of matrix metalloproteinases (MMPs), key destructive enzymes in periodontal disease. Current understanding of periodontal pathogenesis sugge...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-051X.2004.00558.x

    authors: Preshaw PM,Hefti AF,Jepsen S,Etienne D,Walker C,Bradshaw MH

    更新日期:2004-09-01 00:00:00

  • Bone modelling at fresh extraction sockets: immediate implant placement versus spontaneous healing: an experimental study in the beagle dog.

    abstract:OBJECTIVES:The purpose of this investigation is to describe histologically the undisturbed healing of fresh extraction sockets when compared to immediate implant placement. METHODS:In eight beagle dogs, after extraction of the 3P3 and 4P4, implants were inserted into the distal sockets of the premolars, while the mesi...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051X.2011.01803.x

    authors: Vignoletti F,Discepoli N,Müller A,de Sanctis M,Muñoz F,Sanz M

    更新日期:2012-01-01 00:00:00

  • Mandibular and maxillary furcation tunnel preparations--literature review and a case report.

    abstract:AIM:The objective of this literature review and subsequent case report is to discuss and illustrate the tunnel preparation procedure as a treatment alternative for furcation-involved molars. REVIEW OF THE LITERATURE:Furcation tunnel preparation, i.e., the creation of access for plaque control between periodontally dis...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,评审

    doi:

    authors: Rüdiger SG

    更新日期:2001-01-01 00:00:00

  • Association between periodontitis and anti-cardiolipin antibodies in Buerger disease.

    abstract:AIM:Anti-cardiolipin (CL) antibodies can be induced in Buerger disease (BD), an inflammatory occlusive disorder affecting peripheral blood vessels, in response to bacteria bearing homology to the TLRVYK peptide of a phospholipid-binding plasma protein beta-2-glycoprotein I. TLRVYK homologies are present in Porphyromona...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051X.2009.01467.x

    authors: Chen YW,Nagasawa T,Wara-Aswapati N,Ushida Y,Wang D,Takeuchi Y,Kobayashi H,Umeda M,Inoue Y,Iwai T,Ishikawa I,Izumi Y

    更新日期:2009-10-01 00:00:00

  • Late implant placement following ridge preservation versus early implant placement: A pilot randomized clinical trial for periodontally compromised non-molar extraction sites.

    abstract:AIM:To compare late implant placement following alveolar ridge preservation (LP/ARP) and early implantation (EP) in periodontally compromised non-molar extraction sites with respect to soft tissue levels, aesthetics, and patient-reported outcomes. MATERIALS AND METHODS:Sixteen patients were randomly allocated to group...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/jcpe.13223

    authors: Lim HC,Seo S,Thoma DS,Park JC,Hong JY,Shin SY

    更新日期:2020-02-01 00:00:00