Pediatric bipolar spectrum disorder and ADHD: comparison and comorbidity in the LAMS clinical sample.

abstract：OBJECTIVE:Evaluate the efficacy and tolerability of quetiapine (QTP) combined with lithium (Li) or divalproex (DVP) in the treatment of acute mania. METHODS:Patients were randomized to 21 days of double-blind treatment with QTP plus Li/DVP, or placebo (PBO) plus Li/DVP. QTP was rapidly dosed up to a maximum of 800 mg/...

journal_title：Bipolar disorders

authors： Sachs G,Chengappa KN,Suppes T,Mullen JA,Brecher M,Devine NA,Sweitzer DE

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVES:Bipolar disorders are associated with high rates of suicide attempts (SAs) and completions. Several factors have been reported to be associated with suicide in persons with bipolar disorder, but most studies to date have been retrospective and have not utilized multivariate statistics to account for the redu...

journal_title：Bipolar disorders

authors： Marangell LB,Bauer MS,Dennehy EB,Wisniewski SR,Allen MH,Miklowitz DJ,Oquendo MA,Frank E,Perlis RH,Martinez JM,Fagiolini A,Otto MW,Chessick CA,Zboyan HA,Miyahara S,Sachs G,Thase ME

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVES:Recent evidence has demonstrated that corpus callosum maturation follows a similar developmental timeline to cognitive processes. Bipolar disorder (BD) has been associated with disruptions in error processing, response inhibition, and motor functioning, which are mediated by underlying white matter structure...

journal_title：Bipolar disorders

authors： MacMaster FP,Langevin LM,Jaworska N,Kemp A,Sembo M

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVES:Although it is well established that euthymic patients with bipolar disorder can have cognitive impairment, substantial heterogeneity exists and little is known about the extent and severity of impairment within the bipolar II disorder subtype. Therefore, the main aim of this study was to analyze cognitive v...

journal_title：Bipolar disorders

authors： Solé B,Jiménez E,Torrent C,Del Mar Bonnin C,Torres I,Reinares M,Priego Á,Salamero M,Colom F,Varo C,Vieta E,Martínez-Arán A

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVES:To examine the feasibility of collecting course of illness data from patients with bipolar I and II disorder, using weekly text-messaged mood ratings, and to examine the time trajectory of symptom ratings based on this method of self-report. METHODS:A total of 62 patients with bipolar I (n = 47) or II (n = ...

journal_title：Bipolar disorders

authors： Bopp JM,Miklowitz DJ,Goodwin GM,Stevens W,Rendell JM,Geddes JR

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Approximate entropy (ApEn) measures regularity in time series data, while traditional linear statistics measure variability. Using self-reported mood data from patients with bipolar disorder, this preliminary study addressed whether ApEn could distinguish (i) the 60 days prior to the start of a manic or depr...

journal_title：Bipolar disorders

authors： Glenn T,Whybrow PC,Rasgon N,Grof P,Alda M,Baethge C,Bauer M

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVE:An emerging body of evidence supports a role for dysfunctional purinergic neurotransmission in mood disorders. Adenosine agonists have been shown to have properties similar to those of dopamine antagonists; there is a well-characterized interaction between adenosine and dopamine receptors in the ventral stria...

journal_title：Bipolar disorders

authors： Weiser M,Burshtein S,Gershon AA,Marian G,Vlad N,Grecu IG,Tocari E,Tiugan A,Hotineanu M,Davis JM

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVES:We tested the hypothesis that a common functional variant in brain-derived neurotrophic factor (BDNF), Val66Met, which has been shown to be associated with increased body mass index (BMI) in schizophrenia (SCZ) and schizoaffective disorder (SAD), is also associated with antipsychotic-induced weight gain in b...

journal_title：Bipolar disorders

authors： Bonaccorso S,Sodhi M,Li J,Bobo WV,Chen Y,Tumuklu M,Theleritis C,Jayathilake K,Meltzer HY

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVES:Bipolar disorder is associated with positive emotion disturbance, though it is less clear which specific positive emotions are affected. METHODS:The present study examined differences among distinct positive emotions in recovered bipolar disorder (BD) patients (n = 55) and nonclinical controls (NC) (n = 32)...

journal_title：Bipolar disorders

authors： Gruber J,Culver JL,Johnson SL,Nam JY,Keller KL,Ketter TA

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVES:Population isolates offer several advantages for those hoping to identify predisposition genes for bipolar disorder (BP). In this review article, the rationale for performing gene mapping studies in this type of population and the results of genetic mapping studies performed to date in population isolates ar...

journal_title：Bipolar disorders

authors： Escamilla MA

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVES:This study compared the relative risk for hospitalization of patients with bipolar and manic disorders receiving atypical and typical antipsychotics. METHODS:This retrospective study was based on administrative claims data extracted from the PharMetrics database during 1999 through 2003. Comparisons were ma...

journal_title：Bipolar disorders

authors： Gianfrancesco F,Rajagopalan K,Goldberg JF,Wang RH

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:Bipolar major depression differs considerably from unipolar major depression with regard to the efficacy of treatment with antidepressants. In bipolar depression, response to treatment with antidepressants is disappointing. Whether response to electroconvulsive therapy (ECT) differs between bipolar and unipol...

journal_title：Bipolar disorders

authors： Dierckx B,Heijnen WT,van den Broek WW,Birkenhäger TK

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVES:Bipolar affective disorder (BPAD) is clinically and genetically heterogeneous and the affected phenotype is poorly defined, hampering studies of its genetic basis. Studies of specific, familial, clinical indicators of BPAD may be useful for identifying heritable forms. Homogeneous forms of the disease may be...

journal_title：Bipolar disorders

authors： Etain B,Roy I,Henry C,Rousseva A,Schürhoff F,Leboyer M,Bellivier F

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVES:Dopamine transmission abnormalities have been implicated in the etiology of bipolar disorder (BPD). However, there is a paucity of receptor imaging studies in BPD, and little information is available about the dopamine system in BPD. Reuptake of synaptic dopamine by the dopamine transporter (DAT) is the prin...

journal_title：Bipolar disorders

authors： Anand A,Barkay G,Dzemidzic M,Albrecht D,Karne H,Zheng QH,Hutchins GD,Normandin MD,Yoder KK

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:To report a case report of a geriatric patient with a 5-year history of gabapentin use for enhanced bipolar control, who was tapered off of gabapentin over 1 week. The patient displayed unique withdrawal symptoms after the taper of gabapentin. METHODS:The patient is an 81-year-old white female with a life-lo...

journal_title：Bipolar disorders

authors： Tran KT,Hranicky D,Lark T,Jacob Nj

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Depression research historically uses both self- and clinician ratings of symptoms with significant and substantial correlations. It is often assumed that manic patients lack insight and cannot accurately report their symptoms. This delayed the development of self-rating scales for mania, but several scales ...

journal_title：Bipolar disorders

authors： Meyer TD,Crist N,La Rosa N,Ye B,Soares JC,Bauer IE

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVES:Sufficient prefrontal top-down control of limbic affective areas, especially the amygdala, is essential for successful effortful emotion regulation (ER). Difficulties in effortful ER have been seen in patients with bipolar disorder (BD), which could be suggestive of a disturbed prefrontal-amygdala regulation...

journal_title：Bipolar disorders

authors： Zhang L,Opmeer EM,van der Meer L,Aleman A,Ćurčić-Blake B,Ruhé HG

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVES:The pathophysiological mechanisms underlying bipolar disorder and its multi-system nature are unclear. Oxidatively generated damage to nucleosides has been demonstrated in metabolic disorders; however, the extent to which this occurs in bipolar disorder in vivo is unknown. We investigated oxidatively generat...

journal_title：Bipolar disorders

authors： Munkholm K,Poulsen HE,Kessing LV,Vinberg M

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVES:Manic patients exhibit impaired verbal learning and memory, particularly following longstanding illness. However, it is unclear whether recognition and recall performance are differentially influenced by a manic mood state. METHODS:To examine this issue, we administered the California Verbal Learning Test a...

journal_title：Bipolar disorders

authors： Fleck DE,Shear PK,Zimmerman ME,Getz GE,Corey KB,Jak A,Lebowitz BK,Strakowski SM

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVES:Randomized trials of adjunctive psychotherapy for bipolar disorder are reviewed, in tandem with discussion of cost-effectiveness, mediating mechanisms, and moderators of effects. METHODS:Systematic searches of the MEDLINE and PSYCHLIT databases yielded 19 randomized controlled trials of individual family an...

journal_title：Bipolar disorders

authors： Miklowitz DJ,Scott J

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVES:The serotonin hypothesis plays a critical role in the etiology of bipolar disorder (BD). Although many studies have demonstrated reciprocal relationships between serotonin metabolism and immune-inflammatory pathways that occur in depression, studies linking serotonergic function and cytokines are still limit...

journal_title：Bipolar disorders

authors： Hsu JW,Lirng JF,Wang SJ,Lin CL,Yang KC,Liao MH,Chou YH

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVES:To develop a cognitive behavioral intervention for adolescents with bipolar disorders, test its feasibility and preliminary efficacy. METHODS:Based on existing research, a manualized, individually delivered cognitive behavioral intervention was developed and tested with adolescents with bipolar disorders as...

journal_title：Bipolar disorders

authors： Feeny NC,Danielson CK,Schwartz L,Youngstrom EA,Findling RL

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVES:To compare the clinical features and course of major depressive episodes (MDEs) occurring in subjects with bipolar I disorder (BD-I), bipolar II disorder (BD-II), and major depressive disorder (MDD). METHODS:Data were drawn from the National Epidemiologic Survey on Alcohol and Related Conditions (2001-2002)...

journal_title：Bipolar disorders

authors： Moreno C,Hasin DS,Arango C,Oquendo MA,Vieta E,Liu S,Grant BF,Blanco C

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVES:Bipolar disorder is frequently associated with cognitive impairment even during euthymia. Previous studies have reported significant impairments in functional and quality of life outcomes and a possible relationship between these variables and cognitive performance. Cognitive rehabilitation interventions hav...

journal_title：Bipolar disorders

authors： Gomes BC,Rocca CC,Belizario GO,de B F Fernandes F,Valois I,Olmo GC,Fachin RVP,Farhat LC,Lafer B

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVES:To compare the quality of life (QOL) of patients having dual diagnosis of bipolar affective disorder and substance dependence with those having either diagnosis alone and with healthy controls. METHODS:Cross-sectional assessment of the four groups of subjects was made. Euthymic bipolar patients and those su...

journal_title：Bipolar disorders

authors： Singh J,Mattoo SK,Sharan P,Basu D

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVES:Hypotheses regarding mood dysregulation in bipolar disorder (BD) have centered on limbic overactivity with relative prefrontal underactivity during mood episodes. Therefore, we hypothesized that adolescents with bipolar depression successfully treated with lamotrigine would show decreases in amygdalar activa...

journal_title：Bipolar disorders

authors： Chang KD,Wagner C,Garrett A,Howe M,Reiss A

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Bipolar illness is frequently misdiagnosed. Several studies have focused on the underdiagnosis of this condition and the frequent long delay in its recognition. However, the illness is difficult to diagnose and many of its symptoms are shared by other conditions. In order to determine the accuracy of the dia...

journal_title：Bipolar disorders

authors： Stewart C,El-Mallakh RS

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the efficacy and safety of the dopaminergic-enhancing agent modafinil/armodafinil (MoArm) as adjunctive treatment for bipolar depression. METHODS:A comprehensive search of major electronic databases was conducted to identify randomized controlled trials (RCTs) of adjunct...

journal_title：Bipolar disorders

authors： Nunez NA,Singh B,Romo-Nava F,Joseph B,Veldic M,Cuellar-Barboza A,Cabello Arreola A,Vande Voort JL,Croarkin P,Moore KM,Biernacka J,McElroy SL,Frye MA

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVES:  Inflammation and other immune processes are increasingly linked to psychiatric diseases. Antigenic triggers specific to bipolar disorder are not yet defined. We tested whether antibodies to bovine milk caseins were associated with bipolar disorder, and whether patients recognized different epitopes of the ...

journal_title：Bipolar disorders

authors： Severance EG,Dupont D,Dickerson FB,Stallings CR,Origoni AE,Krivogorsky B,Yang S,Haasnoot W,Yolken RH

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVES:Many morphometric magnetic resonance imaging (MRI) studies that have investigated the presence of gray matter (GM) volume abnormalities associated with the diagnosis of bipolar disorder (BD) have reported conflicting findings. None of these studies has compared patients with recent-onset psychotic BD with as...

journal_title：Bipolar disorders

authors： de Azevedo-Marques Périco C,Duran FL,Zanetti MV,Santos LC,Murray RM,Scazufca M,Menezes PR,Busatto GF,Schaufelberger MS

更新日期：2011-02-01 00:00:00