Nonmuscle and smooth muscle myosin isoforms in bovine endothelial cells.

abstract：:Members of the cadherin family of cell adhesion molecules participate in calcium-dependent cell-cell adhesions that are necessary for the cell sorting events that regulate early developmental processes. Although individual cadherin molecules have been shown to participate in tissue histogenesis, the regulation of func...

journal_title：Experimental cell research

authors： Ferreira-Cornwell MC,Veneziale RW,Grunwald GB,Menko AS

更新日期：2000-04-10 00:00:00

abstract：:Bax-mediated apoptosis in neurons is involved in many pathologic conditions affecting the central nervous system, including degenerative diseases, stroke, and trauma. Two molecules belonging to the Bcl-2 family, Bcl-2 and Bcl-X(L), protect cells from Bax-induced apoptosis and show distinct expression patterns in adult...

journal_title：Experimental cell research

authors： Shinoura N,Satou R,Yoshida Y,Asai A,Kirino T,Hamada H

更新日期：2000-02-01 00:00:00

abstract：:There is considerable evidence that the 100- to 116-kDa polypeptides in calf brain coated vesicles are involved in the assembly of clathrin triskelions to form coated vesicles. We have raised polyclonal antibodies against these polypeptides. By Western blot analysis, these antibodies bind to a distinct subset of the s...

journal_title：Experimental cell research

authors： Mosley ST,Branton D

更新日期：1988-02-01 00:00:00

abstract：:Erectile dysfunction (ED) is the most common sexual disorder that men report to healthcare providers. Gap junctions (GJs) are thought to be responsible for synchronous shrinkage of corpus cavernosum smooth muscle cells (CCSMCs), and play thus an important role in the maintenance of an erection. Hypoxia has been sugges...

journal_title：Experimental cell research

authors： Zhang X,Zhao F,Zhao JF,Fu HY,Huang XJ,Lv BD

更新日期：2018-01-15 00:00:00

abstract：:TGFβ contributes to mesangial cell hypertrophy and matrix protein increase in various kidney diseases including diabetic nephropathy. Deptor is an mTOR-interacting protein and suppresses mTORC1 and mTORC2 activities. We have recently shown that TGFβ-induced inhibition of deptor increases the mTOR activity. The mechani...

journal_title：Experimental cell research

authors： Maity S,Bera A,Ghosh-Choudhury N,Das F,Kasinath BS,Choudhury GG

更新日期：2018-03-01 00:00:00

abstract：:Polycystin-2 (PC2, TRPP2) is a nonselective cation channel whose dysfunction is associated with the onset of autosomal dominant polycystic kidney disease (ADPKD). PC2 contributes to Ca2+ transport and cell signaling in renal epithelia and other tissues. Little is known however, as to the external Ca2+ regulation of PC...

journal_title：Experimental cell research

authors： Dai XQ,Perez PL,Soria G,Scarinci N,Smoler M,Morsucci DC,Suzuki K,Cantero MDR,Cantiello HF

更新日期：2017-01-01 00:00:00

abstract：:Pirh2, a recently identified ubiquitin-protein ligase, has been reported to promote p53 degradation. Pirh2 physically interacts with p53 and promotes ubiquitination of p53 independently of MDM2. Like MDM2, Pirh2 is thought to participate in an autoregulatory feedback loop that controls p53 function. We have previously...

journal_title：Experimental cell research

authors： Duan W,Gao L,Wu X,Zhang Y,Otterson GA,Villalona-Calero MA

更新日期：2006-10-15 00:00:00

abstract：:Estrogen receptor-containing cells were identified in uteri of mature and senescent rats by means of quantitative autoradiography. Cell numbers and density were assessed in the various uterine layers. It was determined that despite decreases in receptor concentrations in endometrium, endometrial stroma, myometrium, an...

journal_title：Experimental cell research

authors： Han Z,Kokkonen GC,Roth GS

更新日期：1989-01-01 00:00:00

abstract：:Rat thyroid differentiated cells (PC Cl 3) are an excellent model system with which to study the interaction between differentiation and cell transformation. We previously demonstrated that PC Cl 3 cells expressing the adenovirus E1A gene no longer depend on thyrotropin for growth and do not express thyroid differenti...

journal_title：Experimental cell research

authors： Iuliano R,Trapasso F,Stella A,Le Pera I,Melillo RM,Bruni P,Baldassarre G,Chiariotti L,Santoro M,Viglietto G,Fusco A

更新日期：2000-11-01 00:00:00

abstract：:Mps-one-binder (Mob) proteins play a crucial role in yeast cytokinesis. After cloning two Mob1-like genes, MsMob1-A and MsMob1-B from alfalfa (Medicago sativa L.) we show that, although they are constitutively expressed in roots, stems, leaves, flowers and pods, their transcripts and proteins are mostly produced in ac...

journal_title：Experimental cell research

authors： Citterio S,Piatti S,Albertini E,Aina R,Varotto S,Barcaccia G

更新日期：2006-04-15 00:00:00

abstract：:The ccl mutation in Paramecium tetraurelia reversibly and rapidly blocks cell cycle progression and DNA synthesis at the restrictive temperature. Progression through the cell cycle is blocked during both the G1 and S portions of the cell cycle, while at the restrictive temperature there is neither residual cell cycle ...

journal_title：Experimental cell research

authors： Rasmussen CD,Berger JD

更新日期：1984-12-01 00:00:00

abstract：:Cell migration is part of many important in vivo biological processes and is influenced by chemical and physical factors such as substrate topography. Although the migratory behavior of different cell types on structured substrates has already been investigated, up to date it is largely unknown if specimen's age affec...

journal_title：Experimental cell research

authors： Sales A,Picart C,Kemkemer R

更新日期：2019-01-01 00:00:00

abstract：:Translation is mediated partly by regulation of free eukaryotic initiation factor 4E (eIF4E) levels through PI3K-Akt-mTOR signaling. Cancer cells treated with the plant-derived perillyl alcohol (POH) or the mechanistic target of rapamycin (mTOR) inhibitor rapamycin dephosphorylate eIF4E-binding protein (4E-BP1) and at...

journal_title：Experimental cell research

authors： Sundin T,Peffley D,Hentosh P

更新日期：2013-08-01 00:00:00

abstract：:Protein kinase C (PKC) is a family of Ser/Thr protein kinases categorized into three subfamilies: classical, novel, and atypical. The subcellular localization of classical PKCalpha, -betaI, and -gamma in the process of porcine oocyte maturation, fertilization, and parthenogenetic activation and their involvement in co...

journal_title：Experimental cell research

authors： Fan HY,Tong C,Li MY,Lian L,Chen DY,Schatten H,Sun QY

更新日期：2002-07-15 00:00:00

abstract：:Gallbladder cancer (GBC) is an aggressive malignancy of the bile duct, which is associated with a low (5-year) survival and poor prognosis. The transcription factor HIF-1α is implicated in the angiogenesis, cell survival, epithelial mesenchymal transition (EMT) and invasiveness of GBC. In this study, we have investiga...

journal_title：Experimental cell research

authors： Gao H,Xie J,Peng J,Han Y,Jiang Q,Han M,Wang C

更新日期：2015-03-15 00:00:00

abstract：:Human lacrimal gland biopsies were serially incubated in chelating and enzymatic solutions. Viable single cells were evaluated for outgrowth in growth factor enriched medium using the following culture substrates: Matrigel, Type I collagen gel with or without fibroblasts, and plastic. Each epithelial outgrowth was cha...

journal_title：Experimental cell research

authors： Yoshino K,Tseng SC,Pflugfelder SC

更新日期：1995-09-01 00:00:00

abstract：:Microtubule-binding proteins provide an alternative and vital pathway to the functional diversity of microtubules. Considerable work is still required to understand the complexities of microtubule-associated cellular processes and to identify novel microtubule-binding proteins. In this study, we identify Bcl2-associat...

journal_title：Experimental cell research

authors： He X,Zhang Y,Yang L,Feng J,Yang S,Li T,Zhong T,Li Q,Xie W,Liu M,Zhou J,Li D,Xie S

更新日期：2020-02-01 00:00:00

abstract：:The bone morphogenetic proteins (BMPs) are potent osteoinductive factors that accelerate osteoblast maturation, accompanied by increased cell-substrate adhesion. BMP-2 treatment of osteoblastic cells increases phosphorylation of the cytoplasmic BMP-2 signaling molecules, Smad1 and Smad5. We have previously reported th...

journal_title：Experimental cell research

authors： Nöth U,Tuli R,Seghatoleslami R,Howard M,Shah A,Hall DJ,Hickok NJ,Tuan RS

更新日期：2003-11-15 00:00:00

abstract：:Several cell division cycle (cdc) mutants of Saccharomyces cerevisiae (cdc28, cdc35, cdc19, cdc21, and cdc17) at the restrictive temperature (37 degrees C) in the presence of 1% glucose and defined medium divert most of the carbon (approximately 50%) to ethanol production with low biomass growth yields (Yglc) that cor...

journal_title：Experimental cell research

authors： Mónaco ME,Valdecantos PA,Aon MA

更新日期：1995-03-01 00:00:00

abstract：:The Autoimmune Regulator (AIRE) is a regulator of transcription in the thymic medulla, where it controls the expression of a large set of peripheral-tissue specific genes. AIRE interacts with the transcriptional coactivator and acetyltransferase CBP and synergistically cooperates with it in transcriptional activation....

journal_title：Experimental cell research

authors： Saare M,Rebane A,Rajashekar B,Vilo J,Peterson P

更新日期：2012-08-15 00:00:00

abstract：:We have compared the rate of synthesis, half-life, and steady-state content of the oncoprotein p53 in logarithmically growing cultures of (a) primary embryo, (b) immortalized but untransformed, and (c) spontaneously transformed mouse fibroblasts. Steady-state p53 content derived from metabolic labeling and immunopreci...

journal_title：Experimental cell research

authors： Williams NW,Wynford-Thomas D

更新日期：1989-10-01 00:00:00

abstract：:Nod-like receptor pyrin domain-containing protein 6 (NLRP6) plays a key role in innate immunity, host defense and tumorigenesis. Our previous study has demonstrated the tumor suppressor role of NLRP6 in gastric cancer. In the present study, we explored the interaction protein of NLRP6 by Flag-tagged immunoprecipitatio...

journal_title：Experimental cell research

authors： Wang X,Wu X,Wang Q,Zhang Y,Wang C,Chen J

更新日期：2020-10-01 00:00:00

abstract：:UDP-glucose dehydrogenase (UGDH) catalyzes oxidation of UDP-glucose to yield UDP-glucuronic acid, a precursor of hyaluronic acid (HA) and other glycosaminoglycans (GAGs) in extracellular matrix. Although association of extracellular matrix with cell proliferation and migration has been well documented, the importance ...

journal_title：Experimental cell research

authors： Wang TP,Pan YR,Fu CY,Chang HY

更新日期：2010-10-15 00:00:00

abstract：:The involvement of polyamines in cytokinesis has been examined in eggs of the amphibian X. laevis. Microinjection of spermine or spermidine into unfertilized eggs induced a shortening of the first division cycle and early formation of cleavage-like constrictions. Eggs were activated by injection and developed furrows ...

journal_title：Experimental cell research

authors： Grant NJ,Aimar C,Oriol-Audit C

更新日期：1984-02-01 00:00:00

abstract：:Regions rich in 5-methylcytosine were localized in male metaphase chromosomes of the Indian muntjac deer (Muntiakus muntjak). Chromosomes were ultraviolet irradiated and subsequently photooxidized in the presence of methylene blue to induce maximum DNA denaturation. Following treatment with anti 5-methylcytosine antib...

journal_title：Experimental cell research

authors： Vasilikaki-Baker H,Nishioka Y

更新日期：1983-08-01 00:00:00

abstract：:Hyperglycemia and hyperlipidemia (glycolipotoxicity)-triggered islet β-cell dysfunction is known to drive the progression of obesity-related type 2 diabetes, however the underlying mechanisms have not been clearly elucidated. The current study aimed to investigate the role of mitogen-activated protein kinase phosphata...

journal_title：Experimental cell research

authors： Song Z,Ma J,Lu Y,Zhou C,Zhao T,Ai X,Wei X,Lin J,Wang W,Yan W,Jiao P

更新日期：2019-09-01 00:00:00

abstract：:Infection with Kaposi's sarcoma-associated herpesvirus (KSHV) is a prerequisite for Kaposi's sarcoma, a multicentric endothelial tumor of mixed blood vessel-lymphatic phenotype with a marked production of endothelial basement membrane proteins. The viral K1 gene encodes a unique transmembrane protein capable of transf...

journal_title：Experimental cell research

authors： Mebrahtu S,Eriksson U,Rauch U,Warenholt J,Bendsöe N,Dictor M

更新日期：2004-01-15 00:00:00

abstract：:Poly (ADP-ribose) polymerase-1 (PARP1) is a DNA damage sensor that gets activated in proportion to the damage, helping cells to determine whether to repair the damage or initiate cell death processes. We have previously shown PARP1's significance in the developmental processes of Dictyostelium discoideum in addition t...

journal_title：Experimental cell research

authors： Mir H,Rajawat J,Vohra I,Vaishnav J,Kadam A,Begum R

更新日期：2020-12-15 00:00:00

abstract：:Durations of S-phase (Ts) and total cell cycle times (Tc) were measured from the peripheral blood (PB) and bone marrow aspirates (BM) of five patients with acute nonlymphocytic leukemia (ANLL). Intravenous bromodeoxyuridine (BrdU) was used as the first label for S-phase cells and a monoclonal anti-BrdU antibody was us...

journal_title：Experimental cell research

authors： Raza A,Yasin Z,Grande C

更新日期：1988-05-01 00:00:00

abstract：:Proliferation of human B- and T-lymphoid cell lines including Raji and Akata cells was found to be arrested at the G1 stage in the cell cycle by dimethyl sulfoxide (DMSO). The G1 arrest by DMSO occurred gradually and was completed within 96 h after addition of 1.5% DMSO concomitantly with a decrease in growth rate. Pr...

journal_title：Experimental cell research

authors： Sawai M,Takase K,Teraoka H,Tsukada K

更新日期：1990-03-01 00:00:00