WITHDRAWN: The effect of molecular design on the physical and biological properties of complementary self-assembling peptides.

abstract：:Because tissues are characterized by a well-defined three-dimensional arrangement of cells, tissue engineering scaffolds that facilitate the organization and differentiation of new tissue will have improved performance in comparison to scaffolds that only provide surfaces for cell attachment and growth. We hypothesize...

journal_title：Biomaterials

authors： Koegler WS,Griffith LG

更新日期：2004-06-01 00:00:00

abstract：:A micro-X-ray diffraction (micro-XRD) technique has been employed to determine the phases in two superelastic nickel-titanium orthodontic wires that exhibit shape memory in the oral environment and one superelastic nickel-titanium wire that does not exhibit shape memory in vivo. The micro-XRD analyses were performed o...

journal_title：Biomaterials

authors： Iijima M,Brantley WA,Kawashima I,Ohno H,Guo W,Yonekura Y,Mizoguchi I

更新日期：2004-01-01 00:00:00

abstract：:Bone tissue is an anisotropic non-homogeneous composite material composed of inorganic, bone mineral fibres (hydroxyapatite) embedded in an organic matrix (type I collagen and non-collagenous proteins). Factors contributing to the overall mechanical behaviour include constituent volume fraction, mechanical properties,...

journal_title：Biomaterials

authors： Walsh WR,Guzelsu N

更新日期：1994-01-01 00:00:00

abstract：:Virus-based nanoparticles have shown promise as vehicles for delivering therapeutic genes. However, the rational design of viral vectors that enable selective tropism towards particular types of cells and tissues remains challenging. Here, we explored structural-functional relationships of the adeno-associated virus 2...

journal_title：Biomaterials

authors： Zhang C,Yao T,Zheng Y,Li Z,Zhang Q,Zhang L,Zhou D

更新日期：2016-02-01 00:00:00

abstract：:Nanodiamond application in biotechnological and medical fields is nowadays in continuous progress. In fact, biocompatibility, reduced dimensions and high surface chemical interaction are specific features that make nanodiamonds perfect intracellular carriers of bioactive compounds. By confocal microscopy, we confirmed...

journal_title：Biomaterials

authors： Gismondi A,Reina G,Orlanducci S,Mizzoni F,Gay S,Terranova ML,Canini A

更新日期：2015-01-01 00:00:00

abstract：:A novel technique has been developed for microstructural studies of bone. The spatial organizations of the mineral and collagen fibres in bone have been a matter of discussion for some time, with numerous diverse observations arising from various preparative techniques. In this latest investigation details of the mine...

journal_title：Biomaterials

authors： Green M,Isaac DH,Jenkins GM

更新日期：1985-05-01 00:00:00

abstract：:Titanium can form a bone-like apatite layer on its surface in SBF when it is treated in NaOH. When pre-treated titanium is exposed to SBF, the alkali ions are released from the surface into the surrounding fluid. The Na+ ions increase the degree of supersaturation of the soaking solution with respect to apatite by inc...

journal_title：Biomaterials

authors： Jonásová L,Müller FA,Helebrant A,Strnad J,Greil P

更新日期：2002-08-01 00:00:00

abstract：:Cell labeling using magnetic nanoparticles is an increasingly used approach in noninvasive behavior tracking, in vitro separation of cancer stem cells (CSCs), and CSC-based research in cancer therapy. However, the impact of magnetic labeling on the biological properties of targeted CSCs, such as self-renewal, prolifer...

journal_title：Biomaterials

authors： Wang X,Wei F,Liu A,Wang L,Wang JC,Ren L,Liu W,Tu Q,Li L,Wang J

更新日期：2012-05-01 00:00:00

abstract：:Structural properties of several cross-linked hyaluronan derivatives, obtained by scanning electron microscopy, monodimensional NMR microscopy and small angle X-ray scattering of synchrotron radiation, are presented and compared with those observed for non-modified hyaluronic acid, used as a reference material. The ex...

journal_title：Biomaterials

authors： Gamini A,Paoletti S,Toffanin R,Micali F,Michielin L,Bevilacqua C

更新日期：2002-02-01 00:00:00

abstract：:Inspired by nature's toughening mechanisms, we designed a new polyhedral oligomeric silsesquioxane (POSS)-derived hybrid glass (PHG) that has covalent interactions on the molecular scale between the inorganic POSS cage and organic phase. These features allow "elastic deformation" of the inorganic POSS cage in limited ...

journal_title：Biomaterials

authors： Zhou X,Sahai N,Qi L,Mankoci S,Zhao W

更新日期：2015-05-01 00:00:00

abstract：:Breast cancer is associated with high mortality due to tumor metastasis. The anti-metastasis efficacy of photochemotherapy is strictly limited by poor targeting capability with respect to circulating tumor cells (CTCs) in blood and lymph. Herein, we decorate the platelet membrane (PM) on a surface of nanoparticles (NP...

journal_title：Biomaterials

authors： Ye H,Wang K,Wang M,Liu R,Song H,Li N,Lu Q,Zhang W,Du Y,Yang W,Zhong L,Wang Y,Yu B,Wang H,Kan Q,Zhang H,Wang Y,He Z,Sun J

更新日期：2019-06-01 00:00:00

abstract：:Barium titanate (BaTiO3; BTO) is ferroelectric and piezoelectric after poling treatment. In this study, the bioactivity of BTO was investigated after a poling treatment by examining the formation of crystal growth on specimen surfaces in vitro. Negatively charged BTO surfaces showed calcium phosphate (Ca-P) crystal gr...

journal_title：Biomaterials

authors： Park YJ,Hwang KS,Song JE,Ong JL,Rawls HR

更新日期：2002-09-01 00:00:00

abstract：:Currently available drug-eluting stents (DES) use polymers for coating and releasing drugs. Increasing evidence suggests that inflammatory and hypersensitive reactions are caused by such polymer coatings. This study focused on developing new techniques for delivering drugs directly from metal implant surfaces. Hydroxy...

journal_title：Biomaterials

authors： Mani G,Johnson DM,Marton D,Feldman MD,Patel D,Ayon AA,Agrawal CM

更新日期：2008-12-01 00:00:00

abstract：:Cell-extracellular cell matrix (ECM) interactions play a vital role in development including cytoskeletal structure, growth and differentiation. A 15 amino acid, non-RGD containing, peptide that is derived from type I collagen was tested for its ability to confer cell survival. Two routinely utilized bone graft materi...

journal_title：Biomaterials

authors： Hanks T,Atkinson BL

更新日期：2004-08-01 00:00:00

abstract：:Local delivery systems that provide sustained, high concentrations of antitumor cytokines in the tumor microenvironment while minimizing systemic dissemination are needed to realize the potential of cytokine-based immunotherapies. Recently, co-formulations of cytokines with chitosan solutions have been shown to increa...

journal_title：Biomaterials

authors： Yang L,Zaharoff DA

更新日期：2013-05-01 00:00:00

abstract：:Strangles is an infectious disease caused by Streptococcus equi subspecies equi that affects the upper respiratory tract of the Equidae. The control of this disease seems to be dependent on its earlier detection and prevention, but prolonged animal protection without development of strong and severe side effects has n...

journal_title：Biomaterials

authors： Florindo HF,Pandit S,Gonçalves LM,Videira M,Alpar O,Almeida AJ

更新日期：2009-10-01 00:00:00

abstract：:Silver nanoparticles (AgNPs) have anti-cancer effect. However, whether and how these particles could inhibit the growth of acute myeloid leukemia (AML) cells is unclear. In the present study, we prepared AgNPs with various sizes and investigated their cytotoxic effect on AML cells. We found that AgNPs could inhibit th...

journal_title：Biomaterials

authors： Guo D,Zhu L,Huang Z,Zhou H,Ge Y,Ma W,Wu J,Zhang X,Zhou X,Zhang Y,Zhao Y,Gu N

更新日期：2013-10-01 00:00:00

abstract：:An ideal approach for bone tissue engineering allows for osteoconductivity, osteoinductivity, and cell transplantation. In this study, we examined coprecipitation and surface adsorption schemes with respect to their abilities to control the spatial quantity and localization of a model protein, bovine serum albumin (BS...

journal_title：Biomaterials

authors： Luong LN,Hong SI,Patel RJ,Outslay ME,Kohn DH

更新日期：2006-03-01 00:00:00

abstract：:The Raman laser and infrared spectra of doped bio-active glasses of the 45S5 type are presented and discussed. The spectroscopic results show that the doping agents cause the destruction of the basic glass structure and the consequent formation of SiO4(4-) units in the glass network. When the doped glasses have been i...

journal_title：Biomaterials

authors： Krajewski A,Ravaglioli A,Bertoluzza A,Monti P,Battaglia MA,Pizzoferrato A,Olmi R,Moroni A

更新日期：1988-11-01 00:00:00

abstract：:Dexamethasone, a steroidal anti-inflammatory drug, was incorporated into porous biodegradable polymer scaffolds for sustained release. The slowly released dexamethasone from the degrading scaffolds was hypothesized to locally modulate the proliferation and differentiation of various cells. Dexamethasone containing por...

journal_title：Biomaterials

authors： Yoon JJ,Kim JH,Park TG

更新日期：2003-06-01 00:00:00

abstract：:This experimental investigation aims at revealing the mechanical behaviour and failure pattern of direct fibre-reinforced resin-bonded dental bridge with various designs. To evaluate the overall effects of some newly developed dental materials, in the experiment, genuine composite dental bridge specimens are prepared ...

journal_title：Biomaterials

authors： Li W,Swain MV,Li Q,Ironside J,Steven GP

更新日期：2004-09-01 00:00:00

abstract：:Protein therapeutics targeting inflammatory mediators have shown great promise for the treatment of autoimmunities such as rheumatoid arthritis (RA). However, a significant challenge in this area has been their low in vivo stability and consequently their severely compromised therapeutic efficacy. One such therapeutic...

journal_title：Biomaterials

authors： Pasi S,Kant R,Gupta S,Surolia A

更新日期：2015-02-01 00:00:00

abstract：:The ligand-tethered poly(ethylene oxide-propylene oxide-ethylene oxide) (PEO-PPO-PEO) triblock copolymer was explored to engineer poly(DL-lactic acid) (PDL-LA) material to promote cell attachment and growth. The PEO-PPO-PEO was activated by methyl sulfonyl chloride and the amino acid, and peptide were attached. By ble...

journal_title：Biomaterials

authors： Ji J,Zhu H,Shen J

更新日期：2004-05-01 00:00:00

abstract：:The neutrophil polarization assay, a technique used to measure chemotaxis, was adapted to examine complement activation. Complement activation in serum which had been incubated with metallic and polymeric biomaterials was examined using the neutrophil polarization assay and immunoelectrophoresis assay. In agreement wi...

journal_title：Biomaterials

authors： Remes A,Williams DF

更新日期：1991-08-01 00:00:00

abstract：:A "room-temperature" injection molding approach combined with particulate leaching (RTIM/PL) has been, for the first time, developed in this work to fabricate three-dimensional porous scaffolds composed of biodegradable polyesters for tissue engineering. In this approach, a "wet" composite of particulate/polymer/solve...

journal_title：Biomaterials

authors： Wu L,Jing D,Ding J

更新日期：2006-01-01 00:00:00

abstract：:Single-stranded oligonucleotide-conjugated lipids (ssDNA-PEG-lipids) that associate with the cell membrane confer to the cell an artificial adhesive capability via sequence-specific hybridization to complementary oligonucleotides, forming bonds of double stranded oligonucleotides (dsDNA). Such artificial tethers permi...

journal_title：Biomaterials

authors： Hoffecker IT,Takemoto N,Arima Y,Iwata H

更新日期：2015-01-01 00:00:00

abstract：:As a common receptor for three myelin associated inhibitors, Nogo-66 receptor (NgR) mediates their inhibitory activities on neurite outgrowth in the adult mammalian central nervous system (CNS). Therapeutic vaccination protocol targeting NgR emulsified with Freund's adjuvant (FA) has been used in spinal cord injury (S...

journal_title：Biomaterials

authors： Wang YT,Lu XM,Zhu F,Huang P,Yu Y,Zeng L,Long ZY,Wu YM

更新日期：2011-11-01 00:00:00

abstract：:Here we document the complete process of bioresorption and bone replacement of rods made of forged composites of unsintered hydroxyapatite particles/poly l-lactide (F-u-HA/PLLA) implanted in the femoral medullary cavities of rabbits. Bioresorption, osteoconductive bioactivity and bone replacement were compared in thre...

journal_title：Biomaterials

authors： Shikinami Y,Matsusue Y,Nakamura T

更新日期：2005-09-01 00:00:00

abstract：:The adhesion and growth of cells on silicon dioxide substrata are analysed. The adhesion of human red blood cells to silicon dioxide layers of different depth and doping compares well with that to glass. Rat pheochromocytoma cells also grow on the same substrata. The adhesion of these two biological systems is charact...

journal_title：Biomaterials

authors： Grattarola M,Tedesco M,Cambiaso A,Perlo G,Giannetti G,Sanguineti A

更新日期：1988-01-01 00:00:00

abstract：:The purpose of this study was to quantify and compare the amount of water absorbed by six commercially available resin-modified glass ionomer cements and to investigate the possible influence of time and resin content on water sorption. The materials evaluated included Variglass used as a restoration, base and liner; ...

journal_title：Biomaterials

authors： Yap AU

更新日期：1996-10-01 00:00:00