Cell adhesion to silicon substrata: characterization by means of optical and acoustic cytometric techniques.

abstract：:This study was designed to explore the feasibility of using cartilage-derived morphogenetic protein-1 (CDMP1) induced dermal fibroblasts (DFs) as seed cells and polyglycolide (PGA) as scaffold for fibrocartilage engineering. DFs isolated from canine were expanded and seeded on PGA scaffold to fabricate cell/scaffold c...

journal_title：Biomaterials

authors： Zhao G,Yin S,Liu G,Cen L,Sun J,Zhou H,Liu W,Cui L,Cao Y

更新日期：2009-07-01 00:00:00

abstract：:Leaflet tissue specimens prepared from porcine aortic valves treated with glutaraldehyde at low and high pressures have been subjected to 0.45 x 10(9) accelerated fatigue cycles in Ringer's solution. The waveform or crimped property of the collagen fibres in the leaflet tissue is an essential requirement for its abili...

journal_title：Biomaterials

authors： Broom ND

更新日期：1980-01-01 00:00:00

abstract：:Great efforts have been made to develop suitable bioactive constructs that release growth factors (GFs) in a controlled manner for tissue-regeneration applications. Platelet lysates (PLs) are an affordable source of multiple GFs and other proteins, and show great potential in the wound-healing process. Herein, poly-l-...

journal_title：Biomaterials

authors： Tang Q,Lim T,Wei XJ,Wang QY,Xu JC,Shen LY,Zhu ZZ,Zhang CQ

更新日期：2020-10-01 00:00:00

abstract：:Osteogenic agents, such as bone morphogenetic protein-2 (BMP-2), can stimulate the degradation as well as the formation of bone. Hence, they could impair the osteoconductivity of functionalized implant surfaces. We assessed the effects of BMP-2 and its mode of delivery on the osteoconductivity of dental implants with ...

journal_title：Biomaterials

authors： Liu Y,Enggist L,Kuffer AF,Buser D,Hunziker EB

更新日期：2007-06-01 00:00:00

abstract：:Myotube formation is crucial to restoring muscular functions, and biomaterials that enhance the myoblast differentiation into myotubes are highly desirable for muscular repair. Here, we report the synthesis of electroactive, ductile, and degradable copolymers and their application in enhancing the differentiation of m...

journal_title：Biomaterials

authors： Xie M,Wang L,Guo B,Wang Z,Chen YE,Ma PX

更新日期：2015-12-01 00:00:00

abstract：:As a common receptor for three myelin associated inhibitors, Nogo-66 receptor (NgR) mediates their inhibitory activities on neurite outgrowth in the adult mammalian central nervous system (CNS). Therapeutic vaccination protocol targeting NgR emulsified with Freund's adjuvant (FA) has been used in spinal cord injury (S...

journal_title：Biomaterials

authors： Wang YT,Lu XM,Zhu F,Huang P,Yu Y,Zeng L,Long ZY,Wu YM

更新日期：2011-11-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC), as the fifth most common malignant cancer, develops and progresses mostly in a cirrhotic liver where stiff nodules are separated by fibrous bands. Scaffolds that can provide a 3D cirrhotic mechanical environment with complex native composition and biomimetic architecture are necessary f...

journal_title：Biomaterials

authors： Ma X,Yu C,Wang P,Xu W,Wan X,Lai CSE,Liu J,Koroleva-Maharajh A,Chen S

更新日期：2018-12-01 00:00:00

abstract：:As radio- and chemotherapy-based cancer treatments affect both tumors and healthy tissue, cancer immunotherapy attempts to specifically enhance the natural immune response to tumor cells. In mouse models of cancer, we tested uniform dimercaptosuccinic acid (DMSA)-coated monodisperse magnetic nanoparticles as a deliver...

journal_title：Biomaterials

authors： Mejías R,Pérez-Yagüe S,Gutiérrez L,Cabrera LI,Spada R,Acedo P,Serna CJ,Lázaro FJ,Villanueva A,Morales Mdel P,Barber DF

更新日期：2011-04-01 00:00:00

abstract：:Fibrous polyurethane (FPU) prostheses with or without fibronectin coating and gelatin impregnation and FPU prostheses with or without fibronectin coating were seeded with 4.8 x 10(5) subcultivated dog endothelial cells per cm2 prosthesis. Expanded polytetrafluoroethylene (ePTFE) prostheses with and without fibronectin...

journal_title：Biomaterials

authors： Hess F,Jerusalem R,Reijnders O,Jerusalem C,Steeghs S,Braun B,Grande P

更新日期：1992-01-01 00:00:00

abstract：:Surface biofouling poses an increasing problem in industrial and health care applications, driving research for surface coatings to prevent anti-microbial colonization and characterization of the efficacy of the same. The diversity and increasing sophistication of such coatings, which postulate different types of anti...

journal_title：Biomaterials

authors： Xie X,Möller J,Konradi R,Kisielow M,Franco-Obregón A,Nyfeler E,Mühlebach A,Chabria M,Textor M,Lu Z,Reimhult E

更新日期：2011-07-01 00:00:00

abstract：:Cancer stem cells (CSCs) play pivotal roles in cancer metastasis, and strategies targeting cancer stemness may greatly reduce cancer metastasis and improve patients' survival. The canonical Wnt/β-catenin pathway plays critical roles in CSC generation and maintenance as well as in normal stem cells. Non-specifically su...

journal_title：Biomaterials

authors： Li Y,Xiao Y,Lin HP,Reichel D,Bae Y,Lee EY,Jiang Y,Huang X,Yang C,Wang Z

更新日期：2019-01-01 00:00:00

abstract：:This paper describes a method of foaming a polymer system comprising poly(ethyl methacrylate)/tetrahydrofurfuryl methacrylate (PEMA/THFMA), characterisation of the resulting porosity and use of the foam for chondrocyte culture. The potential for this polymer system to support cartilage repair has been investigated pre...

journal_title：Biomaterials

authors： Barry JJ,Gidda HS,Scotchford CA,Howdle SM

更新日期：2004-08-01 00:00:00

abstract：:Despite its long history and some preliminary work in tissue engineering nearly 30 years ago, electrospinning has not gained widespread interest as a potential polymer processing technique for applications in tissue engineering and drug delivery until the last 5-10 years. This renewed interest can be attributed to ele...

journal_title：Biomaterials

authors： Sill TJ,von Recum HA

更新日期：2008-05-01 00:00:00

abstract：:The thermally responsive cholesteryl end-capped poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide) and cholesteryl grafted poly[N-isopropylacrylamide-co-N-(hydroxymethyl) acrylamide] amphiphilic polymers were synthesized and utilized to encapsulate cyclosporin A (CyA) and indomethacin (IND) within core-shell nanopa...

journal_title：Biomaterials

authors： Chaw CS,Chooi KW,Liu XM,Tan CW,Wang L,Yang YY

更新日期：2004-08-01 00:00:00

abstract：:To evaluate whether cytokeratin expression in human oral epithelial cells could be influenced by implant materials used in dental surgery, passaged human oral gingival epithelial cells were seeded on commercially pure titanium (CP-Ti) or on Ti6Al4V titanium alloy. Confluence was achieved after about 15 days on both su...

journal_title：Biomaterials

authors： Lagneau C,Farges JC,Exbrayat P,Lissac M

更新日期：1998-06-01 00:00:00

abstract：:Excessive production of reactive oxygen species (ROS) is a hallmark feature in nanomaterials (NMs) induced cellular toxicity. However, the inter-relationship between NMs induced ROS generation and the cells innate ability to regulate intracellular ROS level in effecting a particular cellular outcome is currently under...

journal_title：Biomaterials

authors： Setyawati MI,Tay CY,Leong DT

更新日期：2013-12-01 00:00:00

abstract：:One of the major challenges in engineering thick, complex tissues such as cardiac muscle, is the need to pre-vascularize the engineered tissue in vitro to enable its efficient integration with host tissue upon implantation. Herein, we explored new magnetic alginate composite scaffolds to provide means of physical stim...

journal_title：Biomaterials

authors： Sapir Y,Cohen S,Friedman G,Polyak B

更新日期：2012-06-01 00:00:00

abstract：:Novel acid-base reaction cements have been developed for use as controlled release formulations. Many new ones have been discovered and assessed; these include those which are capable of releasing copper, cobalt or selenium singly or in combination. A selection was made of the most suitable formulations for this purpo...

journal_title：Biomaterials

authors： Prosser HJ,Wilson AD,Groffman DM,Brookman PJ,Allen WM,Gleed PT,Manston R,Sansom BF

更新日期：1986-03-01 00:00:00

abstract：:Integrins represent the primary mechanism of cell-extracellular matrix interactions and control cell morphology, proliferation, and differentiation. We have previously shown that substrate-dependent modulation of adsorbed fibronectin (Fn) conformation alters alpha5beta1 integrin binding to Fn and directs C2C12 myoblas...

journal_title：Biomaterials

authors： Stephansson SN,Byers BA,García AJ

更新日期：2002-06-01 00:00:00

abstract：:A series of mesoporous silica nanoparticles (MSNs) were synthesized using the co-structure directing method. A non-cytotoxic anionic surfactant, undec-1-en-11-yltetra(ethylene glycol) phosphate monoester surfactant (PMES), was used as a structure directing agent (SDA) together with aminopropyltrimethoxysilane that fun...

journal_title：Biomaterials

authors： Tsai CH,Vivero-Escoto JL,Slowing II,Fang IJ,Trewyn BG,Lin VS

更新日期：2011-09-01 00:00:00

abstract：:Biomedical alloys may release nickel ions during corrosion phenomena and, in addition to their interaction with oral tissues, these ions may also influence characteristic properties of the immune system cells. The aim of this study was to evaluate the effect of nickel chloride on the expression of functionally distinc...

journal_title：Biomaterials

authors： D'Antò V,Eckhardt A,Hiller KA,Spagnuolo G,Valletta R,Ambrosio L,Schmalz G,Schweikl H

更新日期：2009-03-01 00:00:00

abstract：:Osteoinductive biomaterials are promising for bone repair. There is no direct proof that bone marrow mesenchymal stem cells (BMSCs) home to non-osseous sites and participate in ectopic bone formation induced by osteoinductive bioceramics. The objective of this study was to use a sex-mismatched beagle dog model to inve...

journal_title：Biomaterials

authors： Song G,Habibovic P,Bao C,Hu J,van Blitterswijk CA,Yuan H,Chen W,Xu HH

更新日期：2013-03-01 00:00:00

abstract：:The development of artificial microstructures suited for interfacing of peripheral nerves is not only relevant for basic neurophysiological research but also for future prosthetic approaches. Aim of the present study was to provide a detailed analysis of axonal sprouting and reactive tissue changes after implantation ...

journal_title：Biomaterials

authors： Klinge PM,Vafa MA,Brinker T,Brandis A,Walter GF,Stieglitz T,Samii M,Wewetzer K

更新日期：2001-09-01 00:00:00

abstract：:Premature ovarian failure (POF) is the most frequently occurred disease in ovary. Direct inhibition of mammalian target of rapamycin (mTOR) activity can treat woman POF but brings adverse effects to women. Herein, by rational design of a hydrogelator Nap-Phe-Phe-Asp-Arg-Leu-Tyr-OH (Y) and co-assembling Y with an inhib...

journal_title：Biomaterials

authors： Shi Z,Li X,Wei M,Chen P,Zhang T,Ling X,Zhang J,Zhao C,Wang F,Liang G

更新日期：2020-11-16 00:00:00

abstract：:Periosteum plays a pivotal role in vascularization, ossification and remodeling during the healing process of bone injury. However, there are few studies focused on the construction of artificial implants with periosteum-mimetic effect. To emulate the primary role of natural periosteum or endosteal tissues in bone reg...

journal_title：Biomaterials

authors： Yang G,Liu H,Cui Y,Li J,Zhou X,Wang N,Wu F,Li Y,Liu Y,Jiang X,Zhang S

更新日期：2021-01-01 00:00:00

abstract：:Developing materials that are effective against sexually transmitted pathogens such as Chlamydia trachomatis (Ct) and HIV-1 is challenging both in terms of material selection and improving bio-membrane and cellular permeability at desired mucosal sites. Here, we engineered the prokaryotic bacterial virus (M13 phage) c...

journal_title：Biomaterials

authors： Bhattarai SR,Yoo SY,Lee SW,Dean D

更新日期：2012-07-01 00:00:00

abstract：:The large surface area of highly porous titanium structures produced by additive manufacturing can be modified using biofunctionalizing surface treatments to improve the bone regeneration performance of these otherwise bioinert biomaterials. In this longitudinal study, we applied and compared three types of biofunctio...

journal_title：Biomaterials

authors： Amin Yavari S,van der Stok J,Chai YC,Wauthle R,Tahmasebi Birgani Z,Habibovic P,Mulier M,Schrooten J,Weinans H,Zadpoor AA

更新日期：2014-08-01 00:00:00

abstract：:This study examined the engineering and true axial stress-strain behavior of smooth cylindrical and shallow and deep notched cylindrical test specimens, under applied axial tensile loading using non-contacting methods, of both conventional and highly crosslinked ultra-high molecular weight polyethylenes (UHMWPEs). The...

journal_title：Biomaterials

authors： Sobieraj MC,Kurtz SM,Rimnac CM

更新日期：2005-06-01 00:00:00

abstract：:A series of coumarin fluorophores (1-3), each bearing a double bond conjugated quinoline unit that can undergo a Michael-type reaction with thiol-containing compounds, is reported. These systems, designed to provide so-called turn-on changes in fluorescence response when exposed to thiols, act as fluorescent chemical ...

journal_title：Biomaterials

authors： Jung HS,Han JH,Pradhan T,Kim S,Lee SW,Sessler JL,Kim TW,Kang C,Kim JS

更新日期：2012-01-01 00:00:00

abstract：:Sol-gel derived porous silica carriers for the controlled release of proteins were synthesized using a room temperature process. The materials are intended to serve as both substrates for bone growth as well as to allow incorporated proteins such as growth factors to diffuse out and stimulate cell function and tissue ...

journal_title：Biomaterials

authors： Santos EM,Radin S,Ducheyne P

更新日期：1999-09-01 00:00:00