Abstract:
:The function of non-coding RNA genes largely depends on their secondary structure and the interaction with other molecules. Thus, an accurate prediction of secondary structure and RNA-RNA interaction is essential for the understanding of biological roles and pathways associated with a specific RNA gene. We present web servers to analyze multiple RNA sequences for common RNA structure and for RNA interaction sites. The web servers are based on the recent PET (Probabilistic Evolutionary and Thermodynamic) models PETfold and PETcofold, but add user friendly features ranging from a graphical layer to interactive usage of the predictors. Additionally, the web servers provide direct access to annotated RNA alignments, such as the Rfam 10.0 database and multiple alignments of 16 vertebrate genomes with human. The web servers are freely available at: http://rth.dk/resources/petfold/
journal_name
Nucleic Acids Resjournal_title
Nucleic acids researchauthors
Seemann SE,Menzel P,Backofen R,Gorodkin Jdoi
10.1093/nar/gkr248subject
Has Abstractpub_date
2011-07-01 00:00:00pages
W107-11issue
Web Server issueeissn
0305-1048issn
1362-4962pii
gkr248journal_volume
39pub_type
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