Abstract:
:This study assesses the efficiency of the galactosemia add-on test in neonatal screening performed on regular Guthrie card blood spots. Based on estimated average incidence of galactosemia (1:19,984 newborns) in São Paulo State, Brazil, the study develops a cost-benefit analysis model, using a B/C ratio and a 9.25% annual interest rate in order to decapitalize the results. Sensitivity analysis is also performed, varying (as a function of the interest or discount rate) from 0 and 20% and according to the 95% confidence interval (1:7,494-1:59,953 newborns). The results show that the savings obtained by improved health of galactosemic patients detected early by add-on neonatal screening is superior to the costs (B/C=1.33), characterizing galactosemia add-on testing in neonatal screening as an efficient policy. The lower the prevailing interest rate in the economy, the more efficient the neonatal screening policy.
journal_name
Cad Saude Publicajournal_title
Cadernos de saude publicaauthors
Camelo Junior JS,Fernandes MI,Jorge SM,Maciel LM,Santos JL,Camargo AS Jr,Passador CS,Camelo SHdoi
10.1590/s0102-311x2011000400006subject
Has Abstractpub_date
2011-04-01 00:00:00pages
666-76issue
4eissn
0102-311Xissn
1678-4464pii
S0102-311X2011000400006journal_volume
27pub_type
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