Abstract:
:The dyad comprising eye anomalies and congenital heart defects in the same newborn has been proposed as the best sentinel phenotype for the early detection of rubella embryopathy. Time-space birth prevalence distributions of the eye-heart dyad were described in 36 Brazilian hospitals from the Latin-American Collaborative Study of Congenital Anomalies - ECLAMC network, for the period 1994-2008. Seventy dyad cases observed among 554,531 births showed seasonal variation (Χ² = 5.84; p < 0.05), suggesting an environmental etiology, with an increase in cases in October-March and acrophase in December. The secular distribution of dyad prevalence rates was consistent with the distribution of rubella cases in Brazil, showing a decrease from 1994 to 2004, followed by an increase until 2008. Two geographic clusters were identified, one with high and the other with low dyad prevalence. In the high prevalence cluster, a secular increase was observed, starting in 1999, matching the rubella epidemic waves observed in Brazil in 1998-2000 and 2006.
journal_name
Cad Saude Publicajournal_title
Cadernos de saude publicaauthors
Orioli IM,Camelo JS,Rittler M,Castilla EEdoi
10.1590/s0102-311x2011001000009subject
Has Abstractpub_date
2011-10-01 00:00:00pages
1961-8issue
10eissn
0102-311Xissn
1678-4464pii
S0102-311X2011001000009journal_volume
27pub_type
杂志文章abstract::Alarming trends in the resurgence of vector-borne diseases are anticipated to continue unless more effective action is taken to address the variety of underlying causes. Social factors, anthropogenic environmental modifications and/or ecological changes appear to be the primary drivers. The ecological dimension of vec...
journal_title:Cadernos de saude publica
pub_type: 杂志文章
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
pub_type: 杂志文章,多中心研究
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
pub_type: 杂志文章
doi:10.1590/s0102-311x1995000300026
更新日期:1995-07-01 00:00:00
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
pub_type: 杂志文章,评审
doi:10.1590/s0102-311x1999000400002
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journal_title:Cadernos de saude publica
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doi:10.1590/s0102-311x2006000600020
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journal_title:Cadernos de saude publica
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doi:
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
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