Abstract:
PURPOSE OF REVIEW:To discuss the role of vitamin D in asthma, allergic rhinitis, and chronic rhinosinusitis (CRS). RECENT FINDINGS:Over the last several years, the role of vitamin D in immunomodulation has been studied and shown to have a significant impact on immune function. A causal relationship exists between vitamin D function and innate and adaptive immunity to infections. The mechanisms underlying vitamin D immune actions could be attributed to a paracrine feedback loop that reduces inflammation as well as influencing the differentiation fate of activated CD4 T cells, or the enhancement of suppressor T-cell function; indeed, a combination of these factors may underlie the actions of vitamin D. SUMMARY:Recent findings on the function of vitamin D may explain aspects of the pathophysiology of allergic rhinitis and CRS and may help direct future interventions and treatment of these diseases.
journal_name
Curr Opin Otolaryngol Head Neck Surgauthors
Akbar NA,Zacharek MAdoi
10.1097/MOO.0b013e3283465687subject
Has Abstractpub_date
2011-06-01 00:00:00pages
224-8issue
3eissn
1068-9508issn
1531-6998journal_volume
19pub_type
杂志文章,评审abstract::The presence of cervical lymph node metastasis remains the most significant prognostic indicator of survival and disease recurrence in patients with squamous cell carcinoma of the head and neck. An approximately 50% reduction in 5-year survival rate is seen with the development of lymph node metastasis in patients wit...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/00020840-200304000-00010
更新日期:2003-04-01 00:00:00
abstract:PURPOSE OF REVIEW:To discuss the current indications for ventilation tube placement RECENT FINDINGS:In the past year, several studies have challenged the current guidelines for ventilation tube placement and antibiotic use for otitis media in children. Critics argue that some of these studies have poor scientific vali...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e3283095046
更新日期:2008-10-01 00:00:00
abstract:PURPOSE OF REVIEW:To describe ion and water homeostatic mechanisms in the inner ear, how they are compromised in hearing disorders, and what treatments are employed to restore auditory function. RECENT FINDINGS:The ion and water transport functions in the inner ear help maintain the proper endolymph K concentration re...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e32833d9597
更新日期:2010-10-01 00:00:00
abstract:PURPOSE OF REVIEW:There is currently strong evidence supporting human papilloma virus (HPV) causation in a distinct disease entity of oropharyngeal cancer (OPC), with an increasing incidence worldwide.This review aims to critically analyse whether a change in our management approaches to HPV-positive OPC is now require...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e3283509735
更新日期:2012-04-01 00:00:00
abstract:PURPOSE OF REVIEW:Office-based laryngeal laser surgery was created recently and is emerging as a reliable and practical method of treating a number of laryngeal lesions. This style of minimally invasive surgery is becoming increasingly popular in the United States and abroad. RECENT FINDINGS:Fiber-based lasers and dis...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e3281574582
更新日期:2007-06-01 00:00:00
abstract:PURPOSE OF REVIEW:This article reviews literature pertaining to advances in the reconstruction of segmental mandibular defects in the context of an established standard of care, microvascular transfer of free osteocutaneous flaps. RECENT FINDINGS:Most literature reiterates established reconstructive techniques. Except...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e328355d0f3
更新日期:2012-08-01 00:00:00
abstract:PURPOSE OF REVIEW:The anterolateral thigh free flap has achieved recent popularity in North America for the reconstruction of head and neck defects after ablative surgery. The flap is most often based on either the septocutaneous or musculocutaneous perforators of the descending branch of the lateral circumflex femoral...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/01.moo.0000130575.10656.97
更新日期:2004-08-01 00:00:00
abstract:PURPOSE OF REVIEW:Timing of pediatric nasal surgery has always been a controversial topic. Concern over disrupting growing parts of the face and causing permanent facial deformity has led to a primarily conservative approach. Many surgeons feel that it is prudent to wait until the patient has completed nasal growth aft...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000378
更新日期:2017-08-01 00:00:00
abstract:PURPOSE OF REVIEW:In the surgical management of chronic rhinosinusitis, medical therapy is often used to prevent postoperative complications such as adhesions. These complications often require painful debridements in the clinic or revision surgery. Systemic steroids are not without risk and topical steroids are not id...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000012
更新日期:2014-02-01 00:00:00
abstract::Craniofacial reconstruction may be limited by the paucity of autologous materials available and donor site morbidity. Recent advances in the development of biomaterials have given the reconstructive surgeon new options for restoring form and function. There are now biomaterials (second generation) that can elicit a co...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/00020840-200308000-00004
更新日期:2003-08-01 00:00:00
abstract:PURPOSE OF REVIEW:This article reviews the literature on epistaxis, with a focus on the past 12-18 month, and aims to classify the literature available for this very common otolaryngology emergency. RECENT FINDINGS:Epistaxis can be classified into primary or secondary epistaxis based on cause. It can also be classifie...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e328341e1e9
更新日期:2011-02-01 00:00:00
abstract:PURPOSE OF REVIEW:The increasing magnet strengths used for MRI scanning combined with a greater number and variety of otologic prostheses can lead to possible safety issues. This review examines the specific issues and the conclusions of 33 referenced studies examining those issues. RECENT FINDINGS:Variability of inte...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e328270b8b4
更新日期:2007-10-01 00:00:00
abstract:PURPOSE OF REVIEW:To review the literature on toluidine blue (TBlue) and to discuss the utility of TBlue in assessing and in clinical management of patients with oral mucosal lesions. The literature search was conducted using key word search including oral cancer, oral premalignant lesions, and TBlue and by selecting r...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/moo.0b013e32832771da
更新日期:2009-04-01 00:00:00
abstract:PURPOSE OF REVIEW:This review is designed to update the reader on the current state of nasal endoscopy in the control of epistaxis. Recent articles are reviewed and demonstrate recent developments and results. RECENT FINDINGS:The use of endoscopy for control of anterior and posterior epistaxis is beneficial, with less...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/00020840-200402000-00012
更新日期:2004-02-01 00:00:00
abstract:PURPOSE OF REVIEW:To review the past year's literature regarding recent innovations in surgical instrumentation for craniomaxillofacial surgery. RECENT FINDINGS:Current advances in surgical instrumentation have led to many improvements in the field, allowing greater visualization and precision both before and during p...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e328355a906
更新日期:2012-08-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this review is to highlight recent literature related to the initial management and reconstruction of blast injuries to the head and neck. RECENT FINDINGS:An increasing percentage of combat-related injuries are caused by blast trauma. Management of blast trauma over the last 10 years h...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000285
更新日期:2016-10-01 00:00:00
abstract:PURPOSE OF REVIEW:Swallowing disorders impact the health and quality of millions of lives of patients across the age spectrum. The broad scope of the problem is in contrast to the volume of methods that we have to treat the problem. Investigators are testing interventions that go beyond the swallowing system and are ta...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e3282febd4b
更新日期:2008-06-01 00:00:00
abstract:PURPOSE OF REVIEW:Patients being treated for chronic rhinosinusitis, whether via medical or surgical means, account for a significant percentage of all medical malpractice claims against otolaryngologists. In this study, we present suggestions to help otolaryngologists safeguard against unnecessary claims. RECENT FIND...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000024
更新日期:2014-02-01 00:00:00
abstract:PURPOSE OF REVIEW:The supraclavicular artery island flap is a rotation flap that offers a versatile reconstructive option for head and neck defects. Recent anatomical studies have improved our understanding of the vascular supply of the supraclavicular artery island flap. Furthermore, several published large series des...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e328347f811
更新日期:2011-08-01 00:00:00
abstract:PURPOSE OF REVIEW:Skull base osteomyelitis secondary to malignant otitis externa was first described in 1959. Since then, advances have been made in the diagnosis, treatment, and clinical outcomes of this condition. RECENT FINDINGS:This review discusses the pathophysiology and microbiology of malignant otitis externa....
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/00020840-200310000-00002
更新日期:2003-10-01 00:00:00
abstract:PURPOSE OF REVIEW:Laryngopharyngeal reflux is a widely recognized disorder. Yet, decades after its initial description, debate persists regarding pathophysiology, diagnosis, and treatment. This review addresses current literature on laryngopharyngeal reflux and identifies areas of controversy and future opportunities f...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e32832b2581
更新日期:2009-06-01 00:00:00
abstract:PURPOSE OF REVIEW:The management of nasoethmoid or naso-orbito-ethmoid (NOE) fractures requires a thorough knowledge of the central facial anatomy, surgical techniques, available tools and patient factors to obtain optimal restoration of aesthetic form and function. This review article describes the current methods of ...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e3283631936
更新日期:2013-08-01 00:00:00
abstract:PURPOSE OF REVIEW:Thin caliber transnasal esophagoscopes allow for a rapidly expanding array of office-based esophageal procedures, including botulinum toxin injections, in unsedated patients. RECENT FINDINGS:While botulinum toxin has been used in the esophagus and lower esophageal sphincter for many years, there is n...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e3282f1bf39
更新日期:2007-12-01 00:00:00
abstract:PURPOSE OF REVIEW:Rhinosinusitis is one of the most common medical complaints in the United States, affecting up to 16% of the population. It is associated with over 13 million physician visits per year and an estimated aggregated cost of over $6 billion annually. Patients with chronic rhinosinusitis (CRS) demonstrate ...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e328334f670
更新日期:2010-02-01 00:00:00
abstract:PURPOSE OF REVIEW:Sclerosing bone dysplasias are rare genetic disorders of bone remodeling in which excessive bone formation takes place, resulting in encroachment on neural structures. The infant usually appears normal at birth, and the first sign of a problem only comes when a neurologic deficit develops, usually in ...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/01.moo.0000134441.84110.9e
更新日期:2004-10-01 00:00:00
abstract:PURPOSE OF REVIEW:Little is published regarding variations of skull-base anatomy and their relevance to the performance of endoscopic sinus surgery. Several catastrophic complications have occurred in patients with low-lying skull-base variation. This review's purpose is to make the reader aware of skull-base variation...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/00020840-200502000-00006
更新日期:2005-02-01 00:00:00
abstract:PURPOSE OF REVIEW:This article reviews literature on the scientific background of functional electric stimulation of the immobile larynx, the status of animal pacing trials, and first clinical attempts to establish laryngeal pacing. RECENT FINDINGS:Impaired vocal fold motion is seen following recurrent laryngeal nerve...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e32834cb7ba
更新日期:2011-12-01 00:00:00
abstract:PURPOSE OF REVIEW:The identification of transcriptional activators and repressors of hair cell fates has recently been augmented by the discovery of microRNAs (miRNAs) that can function as post-transcriptional repressors in sensory hair cells. RECENT FINDINGS:miRNAs are approximately 21-nucleotide single-stranded ribo...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章
doi:10.1097/MOO.0b013e32833e0601
更新日期:2010-10-01 00:00:00
abstract:PURPOSE OF REVIEW:Fine needle aspiration is a safe diagnostic technique that is widely employed for lesions of the head and neck. Among head and neck sites, the parotid gland stands apart for the number, diversity and peculiarity of pathologic processes to target this structure. This matchless complexity has prompted a...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/01.moo.0000193184.38310.0a
更新日期:2006-04-01 00:00:00
abstract:PURPOSE OF REVIEW:Endoscopic sinus surgery became the gold standard in inflammatory disorders of the nose and paranasal sinuses, in cerebrospinal fluid leak and epistaxis management, and established its efficacy in the oncology of the region. However, there are certain limitations which make an external approach mandat...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000219
更新日期:2016-02-01 00:00:00