Mechanisms of zidovudine resistance in bacteria.

abstract：:Several imipenem-susceptible and -resistant Aeromonas veronii biovar sobria isolates with different morphologies and antimicrobial susceptibilities recovered from bile samples of a patient with cholangitis were analysed. These isolates belonged to the same clone and the imipenem-resistant strains showed overexpression...

journal_title：Journal of medical microbiology

authors： Sánchez-Céspedes J,Figueras MJ,Aspiroz C,Aldea MJ,Toledo M,Alperí A,Marco F,Vila J

更新日期：2009-04-01 00:00:00

abstract：PURPOSE:This study aimed to evaluate the effect of two types of stress, cold and nutritional, on the viability and the in vitro virulence of the foodborne pathogenic bacteria Listeria monocytogenes. METHODOLOGY:Ten diverse isolates were kept in phosphate-buffered saline (PBS) at optimal (37 °C) or at refrigeration tem...

journal_title：Journal of medical microbiology

authors： Araujo V,Neves E,Silva AC,Martins APL,Brito LC

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:Staphylococcus epidermidis colonies often display several morphologies and antimicrobial susceptibility patterns when cultured from device-related infections, and may represent one or multiple genotypes. Genotyping may be helpful in the clinical interpretation, but is time consuming and expensive. We wanted to ...

journal_title：Journal of medical microbiology

authors： Larssen KW,Nor A,Bergh K

更新日期：2018-02-01 00:00:00

abstract：:Bacteraemia in children is a potentially life-threatening condition. The objective of this study was to determine trends in the aetiology of bacteraemia in children aged 1 month-15 years in England and Wales by collecting data voluntarily reported by National Health Service hospital microbiology laboratories. Over the...

journal_title：Journal of medical microbiology

authors： Henderson KL,Johnson AP,Muller-Pebody B,Charlett A,Gilbert R,Sharland M

更新日期：2010-02-01 00:00:00

abstract：:Haemophilus influenzae serotype b (Hib) vaccines have reduced the amount of invasive Hib disease in immunised infants. However, Hib disease remains in unvaccinated infants and adults and non-capsulate H. influenzae (NCHi) still causes infections, including outbreaks of respiratory disease. Characterisation of strains ...

journal_title：Journal of medical microbiology

authors： Leaves NI,Sisson PR,Freeman R,Jordens JZ

更新日期：1997-03-01 00:00:00

abstract：:Antigen participating in cell-mediated immunity was isolated from a sonic extract of Mycobacterium tuberculosis H37Rv. The purified antigen had a mol. wt 150 000-200 000, based upon its Rf in 7.5% polyacrylamide gel in the presence of sodium dodecyl sulphate. In simple agarose gel electrophoresis it had an Rf of 0.85....

journal_title：Journal of medical microbiology

authors： Hattikudur S,Kamat RS

更新日期：1984-08-01 00:00:00

abstract：:Streptococcus gordonii produces a pheromone heptapeptide, s.g.cAM373, which induces a conjugative mating response in Enterococcus faecalis cells carrying the responsive plasmid, pAM373. We investigated the extent of this intergeneric signaling on DNA acquisition by streptococcal species likely to cohabit oral biofilms...

journal_title：Journal of medical microbiology

authors： Mansfield JM,Herrmann P,Jesionowski AM,Vickerman MM

更新日期：2017-11-01 00:00:00

abstract：:Streptolysin O (SLO) is a potent cytolytic toxin produced by almost all strains of group A streptococci and is considered an important virulence factor for this organism. In this study we investigated the effect of allicin and aqueous garlic extracts on the haemolytic activity of SLO. All tested materials potentially ...

journal_title：Journal of medical microbiology

authors： Arzanlou M,Bohlooli S

更新日期：2010-09-01 00:00:00

abstract：:Monoclonal antibodies (MAbs) N-59 and RU-1 were produced by immunisation of mice with streptokinase secreted by Streptococcus group A, type 12, strain A374 isolated from a patient with post-streptococcal glomerulonephritis (PSGN) and were characterised by Western blot analysis. MAb N-59 recognised antigenic determinan...

journal_title：Journal of medical microbiology

authors： Ohkuni H,Todome Y,Yoshimura K,Yamamoto T,Suzuki H,Yokomuro K,Johnston KH,Zabriskie JB

更新日期：1991-07-01 00:00:00

abstract：:Campylobacter fetus subsp. fetus infection can occur in female sheep, causing infertility or abortion. Despite extensive research on the effect of these bacteria on female fertility, little research has been done on the influence of C. fetus subsp. fetus on the male factor. Our objective was to examine the influence o...

journal_title：Journal of medical microbiology

authors： Zan Bar T,Yehuda R,Hacham T,Krupnik S,Bartoov B

更新日期：2008-11-01 00:00:00

abstract：:Fusobacterium necrophorum, a Gram-negative anaerobe, causes a variety of necrotic infections in humans and animals. There are two subspecies: subsp. necrophorum and subsp. funduliforme. In cattle, subsp. necrophorum is more prevalent and production of leukotoxin is a major virulence factor. The leukotoxin operon (lktB...

journal_title：Journal of medical microbiology

authors： Tadepalli S,Stewart GC,Nagaraja TG,Narayanan SK

更新日期：2008-02-01 00:00:00

abstract：:Current practice guidelines recommend that pulmonary blastomycosis be treated with antifungal agents such as amphotericin B and itraconazole. Echinocandins are not recommended because of poor in vitro activity against Blastomyces dermatitidis and lack of supporting clinical data. We report a case of chronic pulmonary ...

journal_title：Journal of medical microbiology

authors： Mardini J,Nguyen B,Ghannoum M,Couture C,Lavergne V

更新日期：2011-12-01 00:00:00

abstract：:The aim of this study was to examine changes in the systemic immune response during the incubation period and following the onset of clinical swine dysentery, including the recovery period. Ten healthy conventional pigs were inoculated with Brachyspira hyodysenteriae. Blood was sampled at pre-inoculation, at days 4 an...

journal_title：Journal of medical microbiology

authors： Jonasson R,Andersson M,Råsbäck T,Johannisson A,Jensen-Waern M

更新日期：2006-07-01 00:00:00

abstract：:Introduction. Quantification of bacterial load in tissue homogenates in in vivo pharmacodynamic studies is cumbersome and time-consuming.Aim. We therefore developed a new method for quantifying bacterial load in tissue homogenates of animals treated with a β-lactam and β-lactamase inhibitor using growth curves.Methods...

journal_title：Journal of medical microbiology

authors： Georgiou PC,Mouton JW,Pournaras S,Meletiadis J

更新日期：2020-05-01 00:00:00

abstract：:Acute hypercytokinaemia represents an imbalance of pro-inflammatory and anti-inflammatory cytokines, and is believed to be responsible for the development of acute respiratory distress syndrome and multiple organ failure in severe cases of avian (H5N1) influenza. Although neuraminidase inhibitors are effective in trea...

journal_title：Journal of medical microbiology

authors： Carter MJ

更新日期：2007-07-01 00:00:00

abstract：:Pseudomonas aeruginosa is an opportunistic pathogen that poses a threat in clinical settings due to its intrinsic and acquired resistance to a wide spectrum of antibiotics. Additionally, the presence of a subpopulation of cells surviving high concentrations of antibiotics, called persisters, makes it virtually impossi...

journal_title：Journal of medical microbiology

authors： De Groote VN,Fauvart M,Kint CI,Verstraeten N,Jans A,Cornelis P,Michiels J

更新日期：2011-03-01 00:00:00

abstract：:In this study, 250 vaginal samples from patients with vulvovaginal candidosis were inoculated onto two chromogenic media, Albicans ID(2) and Biggy agar, as well as onto Sabouraud chloramphenicol agar, yielding a total of 63 yeast (25.2 %) on all three media. These strains were identified as Candida glabrata in 20 (31....

journal_title：Journal of medical microbiology

authors： Ilkit M,Hilmioglu S,Tasbakan M,Aydemir S

更新日期：2007-06-01 00:00:00

abstract：:Growth of Candida albicans biofilms and production of extracellular matrix were monitored by dry weight, colorimetric and radioisotope assays, and by scanning electron microscopy. Under static incubation conditions synthesis of matrix material was minimal, but increased dramatically when developing biofilms were subje...

journal_title：Journal of medical microbiology

authors： Hawser SP,Baillie GS,Douglas LJ

更新日期：1998-03-01 00:00:00

abstract：:Synergy between fluvastatin, at clinically unachievable concentrations, and fluconazole against Candida albicans has been reported. The purpose of the present study was to evaluate the in-vitro activity of fluconazole alone and in combination with clinically achievable concentrations of pravastatin and fluvastatin aga...

journal_title：Journal of medical microbiology

authors： Nash JD,Burgess DS,Talbert RL

更新日期：2002-02-01 00:00:00

abstract：:The major risk factor for Clostridium difficile infection (CDI) is the use of antibiotics owing to the disruption of the equilibrium of the host gut microbiota. To preserve the beneficial resident probiotic bacteria during infection treatment, the use of molecules with selective antibacterial activity enhances the eff...

journal_title：Journal of medical microbiology

authors： Novakova J,Džunková M,Musilova S,Vlkova E,Kokoska L,Moya A,D'Auria G

更新日期：2014-12-01 00:00:00

abstract：:Helicobacter pylori is believed to trigger neutrophil activation through several factors, including the H. pylori neutrophil-activating protein (HpNAP). The aim of this study was to characterise the factors within H. pylori cell-free extracts that stimulate neutrophil activation. Neutrophil activation was found to be ...

journal_title：Journal of medical microbiology

authors： Leakey A,Hirst R,LA Brooy J

更新日期：2001-09-01 00:00:00

abstract：PURPOSE:Comparative genomic analysis of strains may help us to better understand the wide diversity of their genetic profiles. The aim of this study was to analyse the genomic features of the resistome and virulome of Brazilian first methicillin-resistant Staphylococcus aureus (MRSA) isolates and their relationship to ...

journal_title：Journal of medical microbiology

authors： de Carvalho SP,de Almeida JB,de Freitas LM,Guimarães AMS,do Nascimento NC,Dos Santos AP,Campos GB,Messick JB,Timenetsky J,Marques LM

更新日期：2019-05-01 00:00:00

abstract：:Chemotaxis of polymorphonuclear leukocytes (PMNL) in response to cell components of Bacteroides fragilis alone or in combination with Escherichia coli was evaluated. E. coli produced much more powerful chemotactic factors than B. fragilis. The culture filtrate (CF), outer membrane (OM) preparation, and lipopolysacchar...

journal_title：Journal of medical microbiology

authors： Namavar F,Verweij-Van Vught AM,Bal M,MacLaren DM

更新日期：1987-09-01 00:00:00

abstract：:Cross-reactivity in a delayed-type hypersensitivity (DH) response was studied in mice immunised with live Salmonella typhi, S. paratyphi A and S. paratyphi B. Extensive cross-reactions outside the serogroup limits were observed. The ability of DH cross-reacting and non-cross-reacting sonicates to generate activated ma...

journal_title：Journal of medical microbiology

authors： Tiwari H,Kamat RS

更新日期：1986-05-01 00:00:00

abstract：:The adhesion of bovine and a human isolate of Escherichia coli to epithelial cells from the teat and lactiferous sinuses of the udder was examined. Adhesion was detected with bacterial suspensions that produced mannose-sensitive agglutination of guinea-pig red cells. Adhesion to epithelial cells could be inhibited by ...

journal_title：Journal of medical microbiology

authors： Harper M,Turvey A,Bramley AJ

更新日期：1978-05-01 00:00:00

abstract：:A periplasmic flagellin gene, flaB, of Leptospira interrogans serovar pomona (strain Pomona) was expressed in Escherichia coli for the production and antigenic characterisation of the protein. The flaB structural gene, which was previously cloned into pUC118, was derived by PCR from the recombinant plasmid and used to...

journal_title：Journal of medical microbiology

authors： Lin M,Bughio N,Surujballi O

更新日期：1999-11-01 00:00:00

abstract：:Immunodiffusion analysis of Mycobacterium lepraemurium indicated the presence of at lease six antigens. Comparative analysis of the M. lepraemurium antigen-antibody system with similar systems established for other mycobacterial species, showed that M. lepraemurium shared up to two antigens with other species. Althoug...

journal_title：Journal of medical microbiology

authors： Navalkar RG,Dalvi RR,Patel PJ

更新日期：1975-02-01 00:00:00

abstract：:To analyse the characteristics of infections caused by Streptococcus dysgalactiae subsp. equisimilis, clinical isolates (n=145) were collected at 11 medical institutions between September 2003 and October 2005. These isolates belonged to Lancefield group A (n=5), group C (n=18) or group G (n=122). Among all isolates, ...

journal_title：Journal of medical microbiology

authors： Sunaoshi K,Murayama SY,Adachi K,Yagoshi M,Okuzumi K,Chiba N,Morozumi M,Ubukata K

更新日期：2010-01-01 00:00:00

abstract：:The effect of pretreatment of denture acrylic with chlorhexidine gluconate on the subsequent adherence of Candida albicans GDH 2346 was measured in vitro. Adherence was significantly reduced by pretreatment with chlorhexidine; maximal inhibition was achieved by incubation at room temperature for 30 min in 2% chlorhexi...

journal_title：Journal of medical microbiology

authors： McCourtie J,MacFarlane TW,Samaranayake LP

更新日期：1985-08-01 00:00:00

abstract：:Purpose. In this study, we differentiated between tuberculosis (TB) and infections caused by nontuberculous mycobacteria (NTM) or Nocardia in a tertiary general hospital in China. Differences in clinical manifestations and factors between respiratory infections associated with these organisms were also investigated.Me...

journal_title：Journal of medical microbiology

authors： Dong G,Chu P,Guo J,Xie Y,Lu J

更新日期：2020-09-01 00:00:00