Abstract：
:In developing countries, renal transplantation is offered to young end-stage renal disease (ESRD) patients, while the older ones face limitations due to higher mortality risk. We retrospectively analyzed 225 patients who underwent renal transplantation from living donors, aged 40-60 years (Group A) and >60 years (Group B), focusing on their survival outcome. Group A (n = 181) had mean creatinine (mg/dL) 1.41 ± 0.84, 1.30 ± 0.65 and 1.40 ± 0.60 and mean eGFR (mL/min/1.73 m(2)) of 65.32 ± 23.03, 69.14 ± 32.65 and 59.21 ± 22.79 at 0, 3 and 6 months post-transplantation. Death-censored graft survival was 93.1% in first year followed by 91.2% in subsequent 4 years. Patient survival was 92.5% in first year, 90.7% in the next 2 years, and 89.2% in 4th year. Highest cumulative graft survival was 86.7% in the first year with 83.4%, 82.7% and 82.4% during the subsequent 3 years. Group B (n = 44) had mean creatinine (mg/dL) of 1.46 ± 1.02, 1.29 ± 0.23 and 1.2 ± 0.29 with a mean eGFR (mL/min/1.73 m(2)) of 67.90 ± 23.48, 67.02 ± 12.76 and 75.23 ± 15.19 at 0, 3 and 6 months. Highest death-censored graft survival was 97.4% in the first year with 94.7% in next 3 years. Patient survival was 88.1% throughout 4 years post-transplantation. Cumulative graft survival was 84.1% during 4 years. Biopsy-proven acute rejection rate was 28.7% in group A and 15.9% in group B (P = 0.058). There was higher mortality rate in group B with death mainly due to infections and cardiovascular complication. Cardiovascular risk assessment, pre-transplant cancer screening and judicious use of immunosuppressive agents should help minimize adverse events, balanced with an inherently reduced risk of acute rejection, hence the graft survival advantage and is the way forward to maximize patient and renal allograft survival in elderly patients.
journal_name
Int Urol Nephroljournal_title
International urology and nephrologyauthors
Mohamed Ali AA,Abraham G,Khanna P,Reddy YN,Mehrotra A,Mathew M,Sundararaj S,Jasmine Rdoi
10.1007/s11255-010-9887-4subject
Has Abstractpub_date
2011-03-01 00:00:00pages
265-71issue
1eissn
0301-1623issn
1573-2584journal_volume
43pub_type
杂志文章abstract：BACKGROUND:Although frequent use of prophylactic antibiotics for patients undergoing transrectal prostate biopsy (TRPB), incidences of urinary tract infection (UTI) and bacterial resistance are still increasing. We evaluated the efficacy of augmented prophylactic antibiotics in patients undergoing TRPB. METHODS:A syst...
journal_title：International urology and nephrology
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s11255-016-1299-7
更新日期：2016-08-01 00:00:00
abstract：:The aim of the present study was to examine subpreputial bacteriology and to compare it with the urine cultures of healthy male children. Seventy-two male children were divided into two groups as A and B according to age. In both groups preputial sac and urine cultures were taken simultaneously. Gram (+) enteric cocci...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1023/a:1007120520884
更新日期：2000-01-01 00:00:00
abstract：OBJECTIVE:We analyze the clinical and economical outcomes of an ambulatory care program for the management of patients presenting to the emergency department with acute urinary retention (AUR). METHOD:A standardized ambulatory care program for managing male patients presenting with AUR was established in October 2007....
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-012-0266-1
更新日期：2012-12-01 00:00:00
abstract：:We have been using the flexible cystoscope since 1987. Detailed information is given concerning the technique of flexible cystoscopy, its indications, advantages and disadvantages. A comparison is made with the results obtained using the rigid cystoscope in an initial series of 100 patients, yielding false negative re...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02549531
更新日期：1992-01-01 00:00:00
abstract：PURPOSE:To compare the efficacy and safety of two approaches in retroperitoneoscopic renal pedicle lymphatic disconnection (RRPLD) for intractable chyluria: completely or partly mobilize the kidney. MATERIALS AND METHODS:Retrospectively reviewed the clinical data of 77 patients, who underwent RRPLD because of intracta...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-016-1351-7
更新日期：2016-10-01 00:00:00
abstract：:Lowering dietary protein intake (DPI) to approximately 0.6-0.8 g/kgBW/day may be renoprotective through various mechanisms, and it has been recommended in patients with non-dialysis-dependent chronic kidney disease (NDD-CKD) as a means to also control various metabolic consequences of advanced CKD, such as uremic symp...
journal_title：International urology and nephrology
pub_type： 社论
doi：10.1007/s11255-016-1224-0
更新日期：2016-05-01 00:00:00
abstract：OBJECTIVES:To examine symptomatology and microbiology of infected lymphocele (LC) post-robotic-assisted radical prostatectomy and pelvic lymph node dissection (PLND) and to assess for potential predictors for LC fluid culture positivity. Secondly, to provide general recommendations about use of select antimicrobial the...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-017-1599-6
更新日期：2017-07-01 00:00:00
abstract：:In a retrospective study of 522 consecutive patients who were subjected to transurethral resection of the prostate with suprapubic trocar technique, six patients were suspected of having transurethral prostatic resection syndrome. The majority of the transurethral resections were performed by surgical or urological tr...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02550468
更新日期：1987-01-01 00:00:00
abstract：:To report a rare congenital anomaly of the genitourinary tract, renal dysplasia is associated with ipsilateral incomplete duplicated ectopic ureter and seminal vesicle cyst in an adult, successfully treated with robotic-assisted laparoscopic approach. ...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-013-0412-4
更新日期：2013-06-01 00:00:00
abstract：PURPOSE:To investigate the effect of intradialytic resistance exercise on inflammation markers and sarcopenia indices in maintenance hemodialysis (MHD) patients with sarcopenia. METHODS:Forty-one MHD patients with sarcopenia were divided into an intervention group (group E, n = 21) and a control group (group C, n = 20...
journal_title：International urology and nephrology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s11255-019-02200-7
更新日期：2019-08-01 00:00:00
abstract：PURPOSE:To prove that phosphodiesterase type-4 inhibitors could potentially treat obesity-associated overactive bladder through modulation of the systemic inflammatory response. METHODS:In this 12-week study, 90 female Sprague-Dawley rats were divided into three groups: (1) vehicle-treated normal diet (ND)-fed rats; (...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-017-1671-2
更新日期：2017-10-01 00:00:00
abstract：PURPOSE:A region of chromosome 22 which includes APOL1 and MYH9 genes was recently identified as a risk locus for non-diabetic forms of kidney disease, including idiopathic and HIV-associated focal segmental glomerular sclerosis and kidney disease clinically attributed to hypertension among African Americans. The purpo...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-012-0263-4
更新日期：2013-04-01 00:00:00
abstract：AIM:To evaluate the infectious complications, microorganism distribution and antibacterial treatment in patients who underwent percutaneous nephrolithotomy (PCNL). PATIENTS AND METHODS:Three hundred and thirty-eight patients who were 17 years age or older who underwent PCNL between January 2001 and December 2002 have ...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-006-9147-9
更新日期：2007-01-01 00:00:00
abstract：PURPOSE:TNF-α -308G/A polymorphism has been implicated in the susceptibility of diabetic nephropathy, but studies have reported inconclusive results. The present study investigated the relationship between -308G/A polymorphism in the TNF-α gene and diabetic nephropathy risk by meta-analysis. METHODS:Data from PubMed, ...
journal_title：International urology and nephrology
pub_type： 杂志文章,meta分析
doi：10.1007/s11255-013-0490-3
更新日期：2013-12-01 00:00:00
abstract：:We report a case involving a 55-year-old healthy man that presented with urinary retention and a lower abdominal mass. His evaluation revealed a large mucocele arising from the appendix that caused severe bilateral ureteral obstruction and renal failure. Appendiceal mucoceles are rare and insidious entities that can p...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-005-0917-6
更新日期：2005-01-01 00:00:00
abstract：BACKGROUND:We reviewed our experience with ureteral complications and secondary ureteral implantation after kidney transplantation. METHODS:Between 1997 and 2005, 636 patients underwent kidney transplantation at our transplant center. Ureteral implantation was performed in the Lich-Gregoire technique. Thirty-one patie...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-010-9893-6
更新日期：2011-09-01 00:00:00
abstract：:We report on our experience with a new surgical procedure of forming a pseudoneotesticle from indigenous tissues obtained from the existing scrotal contents. This procedure has been performed in 32 patients with a diagnosis of hormone dependent cancer of the prostate as a therapeutic manoeuvre, and in 3 children who h...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02550317
更新日期：1998-01-01 00:00:00
abstract：:To evaluate cancer involvement of internal female genitalia of patients undergoing anterior exenteration for clinically organ confined transitional cell carcinoma of the bladder, and identify potential preoperative risk factors. Charts and anterior exenteration specimens from 54 women with clinically organ confined tr...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-006-9158-6
更新日期：2007-01-01 00:00:00
abstract：:To compare the two conventional surgical methods for varicocelectomy, 50 patients with varicocele were operated by using either the retroperitoneal or the inguinal techniques. Compliance with local anaesthesia was found to be poor in the retroperitoneal group. The operative time was significantly shorter (p = 0.00038)...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02768286
更新日期：1994-01-01 00:00:00
abstract：:El-Far and Sobh were the first to describe abnormalities in porphyrin metabolism in Egyptian patients with chronic renal failure (CRF). Our results were confirmed by others. The present investigation aims to study and discuss the nature of those abnormalities and changes in porphyrin metabolism in CRF patients followi...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02583996
更新日期：1991-01-01 00:00:00
abstract：:Hydatid disease of the urinary tract is very rare. We report a case of pure renal hydatid cyst, with its clinical presentation and management. ...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02551409
更新日期：1997-01-01 00:00:00
abstract：PURPOSE:The aim of this study was to investigate the number of autophagosomes in podocyte from kidney tissue of immunoglobulin A nephropathy (IgAN) and idiopathic membranous nephropathy (IMN). METHODS:The changes in kidney tissue pathology were detected after hematoxylin and eosin, periodic acid-Schiff, Masson's trich...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-016-1398-5
更新日期：2016-12-01 00:00:00
abstract：:Two cases of condyloma acuminatum of the male urethra were clearly demonstrated by retrograde urethrogram and endoscopy. Characteristic urethrographic and endoscopic appearances of these cases are presented. ...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02082718
更新日期：1986-01-01 00:00:00
abstract：PURPOSE:The objective of the present study is to analyze long-term testicular cancer (TC) survivors focusing on the correlation of therapeutic modalities used, the age of patients and second malignancy (SM) occurrence. PATIENTS AND METHODS:A total of 1,367 patients with TC and different subsequent therapeutic procedur...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-013-0554-4
更新日期：2014-04-01 00:00:00
abstract：PURPOSE:To suggest a different method for diagnosing vesicoureteral reflux (VUR) in lieu of voiding cystourethrography (VCU), in order to prevent radiation exposure. MATERIALS AND METHODS:Fifty-two ureterorenal units of 26 patients were evaluated ultrasonographically for visualizing the renal collecting systems, both ...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02550307
更新日期：1998-01-01 00:00:00
abstract：BACKGROUND:Several techniques have been used to repair mid-penile hypospadias; however, high failure rates and major complications have been reported. In this study, we describe a novel technique using a well-vascularized flap of the inner and outer preputial skin. METHODS:A total of 110 male children with hypospadias...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-016-1416-7
更新日期：2016-12-01 00:00:00
abstract：OBJECTIVE:The current study was carried out to assess the effects of omega-3 fatty acid and alpha-tocopherol co-supplementation on malnutrition-inflammation score (MIS), biomarkers of inflammation and oxidative stress in chronic hemodialysis (HD) patients. METHODS:In a randomized double-blind placebo-controlled clinic...
journal_title：International urology and nephrology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s11255-016-1399-4
更新日期：2016-11-01 00:00:00
abstract：PURPOSE:So far, studies have not clearly identified infectious agents as an etiological factor for interstitial cystitis (IC). Specific microbiological diagnosis for detecting the pathogen with higher sensitivity in IC may decrease the treatment costs and increase psychosocial health of the patients. METHODS:A prospec...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-019-02248-5
更新日期：2019-11-01 00:00:00
abstract：:We report an unusual case of benign recurrent pheochromocytoma that developed at the same site 8 years following initial treatment. This tumor was managed successfully through the 11th rib bed using the transperitoneal extrapleural approach. ...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1023/a:1021309023695
更新日期：2002-01-01 00:00:00
abstract：:Electrically induced bulbocavernosus (BC) reflexes were investigated in 47 patients with benign prostatic hypertrophy and the possible harmful effects of prostatectomy on the pudendal nerve branches were followed up in 30 of the patients using the same method. BC reflex obtained by electrical stimulation of the glans ...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02082074
更新日期：1981-01-01 00:00:00
