Recanalization therapy for acute ischemic stroke, part 2: mechanical intra-arterial technologies.

Abstract:

:Stroke therapy has been revolutionized in the past two decades with the widespread implementation of chemical thrombolysis for acute stroke. However, chemical thrombolysis continues to be limited in its efficacy secondary to relatively short time windows and a high associated risk of hemorrhage. In an attempt to minimize hemorrhagic complications and extend the available therapeutic window, mechanical devices designed specifically for thrombus removal, clot obliteration, and arterial revascularization have experienced a recent surge in development and utilization. As such, chemical thrombolytics now represent only one of many options in acute stroke therapy. These new mechanical devices have extended the potential treatment window and now provide alternatives to patients who do not respond to conventional intravenous thrombolysis. This review will discuss the development of these devices, supporting literature, and the individual strengths that each engenders towards a life-saving therapy for stroke.

journal_name

Neurosurg Rev

journal_title

Neurosurgical review

authors

Ansari S,Rahman M,McConnell DJ,Waters MF,Hoh BL,Mocco J

doi

10.1007/s10143-010-0294-1

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

11-20

issue

1

eissn

0344-5607

issn

1437-2320

journal_volume

34

pub_type

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