Abstract：
:Gutta-percha (GP) has been the most widely used root canal filling material because of its well-known low toxicity. The inertness of GP, however, was challenged recently. The purpose of this study was to evaluate the toxicity of marketed endodontic GP using the radiochromium release test. Fourteen commercially available and three experimental GP brands were tested. Raw GP, zinc oxide, and barium sulfate, which were considered major components of GP points, and zinc ions were also evaluated. The material was spread to cover the bottom of testing wells after being dissolved in chloroform or warmed. A labeled suspension of L929 cells was added to the wells. After incubation at 37 degrees C for 4 and 24 h, extracellular radiochromium in the culture medium was measured and calculated in percentage of the total intracellular label. Spontaneous release of radiochromium was used as control and the results were considered to be within normal limits either at 4 or 24 h. All chloroform-dissolved GP showed low toxicity at 4 h, whereas warmed GP showed statistically significant differences at 4 h. Both dissolved and warmed GP were toxic at 24 h. The raw materials and barium sulfate were not toxic, whereas zinc oxide and zinc ions showed marked toxicity. All GP points tested were toxic at longer observation periods, and the toxicity was attributed to leakage of zinc ions into the fluids.
journal_name
J Endodjournal_title
Journal of endodonticsauthors
Pascon EA,Spångberg LSdoi
10.1016/s0099-2399(06)81885-6subject
Has Abstractpub_date
1990-09-01 00:00:00pages
429-33issue
9eissn
0099-2399issn
1878-3554pii
S0099-2399(06)81885-6journal_volume
16pub_type
杂志文章abstract：INTRODUCTION:The purpose of this study was to evaluate the tooth structure theoretically required to be removed in the coronal and cervical regions to accomplish 3 different endodontic access preparations in a novel digital model. The deviation of the center of access cavity from the central fossa will also be measured...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2020.01.002
更新日期：2020-04-01 00:00:00
abstract：INTRODUCTION:The objective of this study was to investigate the expression of matrix metalloproteinases (MMPs) in apical periodontitis and during the periapical healing phase after root canal treatment. METHODS:Apical periodontitis was induced in dog teeth, and root canal treatment was performed in a single visit or b...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2009.10.030
更新日期：2010-02-01 00:00:00
abstract：INTRODUCTION:Apical surgery is frequently indicated in maxillary first molars. Occasionally, a vascular anastomosis in the lateral maxillary sinus wall can be observed during surgery. The aim of this study was to examine the distance between the vascular bone channel (VBC) and the root apices of maxillary first molars ...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2019.09.004
更新日期：2019-12-01 00:00:00
abstract：:It is known that many factors participate in the process of inflammation and pain transmission. Recently, various neuropeptides have been demonstrated in the intrapulpal nerve fibers immunobiohistochemically. These neuropeptides may play some role in the process of inflammation and transmission of pain sensation. In t...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(06)81566-9
更新日期：1990-02-01 00:00:00
abstract：INTRODUCTION:The lysyl oxidase (LOX) family is an emerging family of amine oxidases responsible for the formation of collagen fibrils in the extracellular matrix. To date, 5 LOX family genes have been identified in humans, encoding LOX and LOX-like proteins (LOXL, LOXL2, LOXL3, and LOXL4). The goal of this study was to...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2012.03.014
更新日期：2012-06-01 00:00:00
abstract：:Inflammation in the dental pulp is accompanied by release of a wide variety of highly oxidative molecules known as reactive oxygen species (ROS). ROS concentrations are controlled in vivo by an antioxidant enzyme scavenger system that may be overwhelmed by the increases in ROS production seen during inflammation. Supp...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1097/00004770-200103000-00014
更新日期：2001-03-01 00:00:00
abstract：INTRODUCTION:Dentin regeneration is one of the main goals of vital pulp treatment in which the biological properties of dental pulp cells (DPCs) need to be considered. In our previous study, we showed that EDTA could enhance the stromal cell-derived factor 1 alpha-induced migration of DPCs. The purpose of this study wa...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2020.12.003
更新日期：2020-12-20 00:00:00
abstract：INTRODUCTION:The aim of this study was to evaluate the root canal preparation in flat-oval canals treated with either rotary or self-adjusting file (SAF) by using micro-tomography analysis. METHODS:Forty mandibular incisors were scanned before and after root canal instrumentation with rotary instruments (n = 20) or SA...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2011.03.017
更新日期：2011-07-01 00:00:00
abstract：INTRODUCTION:Pure gutta-percha (trans-1, 4-polyisoprene [TPI]) has been used extensively as a main component of gutta-percha for root canal filling. TPI has the interesting shape memory property by cross-linking, and this polymer was commercialized under the product name of SMP-2 (Kuraray Corp, Kashima, Japan). Therefo...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2014.05.003
更新日期：2014-10-01 00:00:00
abstract：INTRODUCTION:Dens invaginatus is a critical condition for endodontic treatment once it frequently presents a complex internal anatomy and might be associated with incomplete root and apical development. METHODS:Three cases of dens invaginatus with open apex in maxillary lateral incisors are presented. In the first cas...
journal_title：Journal of endodontics
pub_type： 杂志文章,评审
doi：10.1016/j.joen.2010.02.002
更新日期：2010-06-01 00:00:00
abstract：INTRODUCTION:The management of endodontic emergencies has been particularly challenging during the coronavirus disease 2019 (COVID-19) outbreak because of the possible generation of airborne particles and aerosols. The aim of this report was to contribute to the practice of endodontics by proposing a general protocol f...
journal_title：Journal of endodontics
pub_type： 杂志文章,评审
doi：10.1016/j.joen.2020.09.018
更新日期：2021-01-01 00:00:00
abstract：:The effects of various cleaning, chemical disinfection, and sterilization procedures on the cutting efficiency of endodontic instruments Unifile (De Trey, Bois Colombes, France), (Flexofile Maillefer, Ballaigues, Switzerland), and H-File (Maillefer)) were investigated. The cross-infection control treatment procedures ...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(96)80059-8
更新日期：1996-12-01 00:00:00
abstract：INTRODUCTION:The aim of this study was to compare the efficacy of passive ultrasonic irrigation (PUI) and the EndoVac (EV) System (Discus Dental, Culver City, CA) in hard tissue debris removal and its influence on the quality of the root canal filling with the aid of micro-computed tomographic scanner. METHODS:Twenty-...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2015.05.001
更新日期：2015-10-01 00:00:00
abstract：INTRODUCTION:The primary aim was to explore the criteria used in characterization of reparative cells and mineralized matrices formed after treatment of pulp exposures, and the sequence of relative events. The secondary aim was to evaluate whether the reparative events depend on the experimental model species, age, and...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2018.12.002
更新日期：2019-03-01 00:00:00
abstract：:A palatogingival groove is an anatomic malformation that predisposes the involved tooth to a severe periodontal defect. When the condition is complicated by pulpal necrosis, affected teeth often present a dilemma in terms of diagnosis and treatment planning. In this report, we describe the case of a patient with a max...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2015.10.009
更新日期：2016-02-01 00:00:00
abstract：INTRODUCTION:The study was designed as a randomized double-blind trial to evaluate the anesthetic efficacy of 4% articaine with 1:100,000 epinephrine in inferior alveolar nerve block (IANB) and infiltration anesthetic techniques to anesthetize mandibular molars with irreversible pulpitis. METHODS:The study was compose...
journal_title：Journal of endodontics
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.joen.2011.09.009
更新日期：2011-12-01 00:00:00
abstract：INTRODUCTION:Alkaline-tolerant bacteria in primary infected root canals could have enhanced survival capacity against antimicrobials commonly used in root canal treatment. The aims of this study were to isolate and characterize alkaline-tolerant bacteria before endodontic treatment (S1), after chemomechanical root cana...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2014.12.003
更新日期：2015-04-01 00:00:00
abstract：:Understanding the chemical and physical characteristics of set mineral trioxide aggregate (MTA) surface can provide insight into its bioactivity. The purpose of this study was to describe the surface chemistry and morphology of gray and white MTA set in the presence of fetal bovine serum (FBS). Eight MTA blocks were p...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2007.09.013
更新日期：2008-01-01 00:00:00
abstract：:This study describes three methods of computerized three-dimensional reconstruction of the main neurovascular pulpal bundle of human teeth, using serial cross-paraffin sections, digital image processing, and three-dimensional computer graphics. These methods are surface representation, representation by means of a sta...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/s0099-2399(06)80521-2
更新日期：1995-10-01 00:00:00
abstract：INTRODUCTION:The aim of this study was to determine the extent of disinfection mediated by 2 concentrations of sodium hypochlorite for bacteria-laden dentin wall of a root canal. METHODS:A dual-species film, Enterococcus faecalis and Porphyromonas gingivalis, was cultivated on root canal dentin for 7 days. The canal w...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2013.09.045
更新日期：2014-06-01 00:00:00
abstract：INTRODUCTION:The purpose of this prospective, randomized, single-blinded study was to measure the degree of anesthesia obtained with 1.8 mL and 3.6 mL of 2% lidocaine with 1:100,000 epinephrine in posterior superior alveolar (PSA) nerve blocks. METHODS:Thirty-one adult subjects randomly received PSA nerve blocks of 1....
journal_title：Journal of endodontics
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.joen.2010.01.009
更新日期：2010-04-01 00:00:00
abstract：:Mineral trioxide aggregate (MTA) is being advocated for vital pulp therapy. In the case of direct pulp capping, hemorrhage control is an important step on success, but little is known about the effect of MTA on pulpal bleeding. In addition, there has been a lack of information on the effect of MTA on smooth muscle con...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2007.03.007
更新日期：2007-07-01 00:00:00
abstract：INTRODUCTION:The aim of this prospective, randomized, double-blind clinical trial was to evaluate the effect of a preoperative, single, oral dose of diclofenac potassium (DFK) on postoperative pain and rescue analgesic intake in patients with symptomatic irreversible pulpitis in mandibular molars treated in 1 visit. M...
journal_title：Journal of endodontics
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.joen.2020.05.008
更新日期：2020-08-01 00:00:00
abstract：:The purpose of this study was to evaluate the effect of different irrigating solutions on smear layer removal and dentinal tubule opening on root canal surfaces after post space preparation and to study whether additional ultrasonic irrigation has any effect on smear layer removal. Forty-eight anterior teeth were trea...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2009.01.006
更新日期：2009-04-01 00:00:00
abstract：:The purpose of this study was to compare torque force and rotation needed to fracture three types of nickel titanium alloy rotary instruments in a simulated curved root canal space that were bound at the file tip. Files of similar size tips were studied. The files studied were ProFiles with 0.04 taper diameters of 15,...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1097/01.don.0000148867.30520.9e
更新日期：2005-06-01 00:00:00
abstract：:EDTA-T and 10% citric acid used as root canal irrigants lead to more visible dentinal tubules than 5% sodium hypochlorite associated with 3% hydrogen peroxide. However, these cleansing agents must be compatible with apical periodontal tissue. We analyzed the cytotoxicity of 10% citric acid and EDTA-T in cultured fibro...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1097/00004770-200112000-00007
更新日期：2001-12-01 00:00:00
abstract：:This report presents an unusual indication for root resection of a lower molar tooth and also reviews the history of root resection. ...
journal_title：Journal of endodontics
pub_type： 杂志文章,评审
doi：10.1097/00004770-200004000-00016
更新日期：2000-04-01 00:00:00
abstract：INTRODUCTION:The purpose of this study was to visualize the stresses and strain distribution patterns in ProTaper Universal F2 files (Dentsply Maillefer, Ballaigues, Switzerland) and to establish the stress- and strain-curvature relationship for this instrument under various conditions by using a dynamic, three-dimensi...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2011.06.003
更新日期：2011-10-01 00:00:00
abstract：:The purpose of this study was to compare the cleaning efficacy of passive ultrasonic activation with that of passive sonic activation after hand instrumentation. Sixty curved molar canals were hand-instrumented to size 35 and divided into three groups. Group 1 received no further treatment. Group 2 received 3 min of p...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(99)80120-4
更新日期：1999-11-01 00:00:00
abstract：:Amalgam cores with cemented dowels are commonly used to restore endodontically treated teeth. These restorations were widely studied for their mechanical properties; however, less is known about their sealing ability. The effect of the cement type used for the dowel and that of a bonding agent application were studied...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1097/00004770-200104000-00015
更新日期：2001-04-01 00:00:00
