Abstract:
OBJECTIVE:To examine the relationship between functional limitation, socioeconomic inequality, and depression in a diverse cohort of patients with rheumatoid arthritis (RA). METHODS:The study design was cross-sectional and subjects were from the University of California, San Francisco RA Cohort. Patients were enrolled from 2 rheumatology clinics, an urban county public hospital and a university tertiary care medical center. Age, sex, race/ethnicity, disease activity, functional limitation, and medications were variables collected at clinical visits. The patient's clinic site was used as a proxy for his or her socioeconomic status. The outcome variable was depressive symptom severity measured by the Patient Health Questionnaire 9. Differences in characteristics between depressed and nondepressed patients were calculated using 2-sided t-tests or the Pearson's chi-square test. For the multivariate analysis, repeated measures with generalized estimating equations were used. RESULTS:There were statistically significant differences between depressed and nondepressed patients related to race/ethnicity, public versus tertiary care hospital rheumatology clinic, disability, and medications. In the multivariate analysis, increased functional limitation and public clinic site remained significantly associated with increased depression scores. A significant interaction existed between clinic site and disability. Mean depression scores rose more precipitously as functional limitation increased at the public hospital rheumatology clinic. CONCLUSION:There are disparities in both physical and mental health among individuals with low socioeconomic status. The psychological effects of disability vary in patients with RA such that a vulnerable population with functional limitations is at higher risk of developing depressive symptoms.
journal_name
Arthritis Care Res (Hoboken)journal_title
Arthritis care & researchauthors
Margaretten M,Barton J,Julian L,Katz P,Trupin L,Tonner C,Graf J,Imboden J,Yelin Edoi
10.1002/acr.20345subject
Has Abstractpub_date
2011-02-01 00:00:00pages
240-6issue
2eissn
2151-464Xissn
2151-4658journal_volume
63pub_type
杂志文章abstract:OBJECTIVE:The goal of this study was to determine the sensitivity of the new 2013 classification criteria for systemic sclerosis (SSc; scleroderma) in an independent cohort of SSc subjects and to assess the contribution of individual items of the criteria to the overall sensitivity. METHODS:SSc subjects from the Canad...
journal_title:Arthritis care & research
pub_type: 杂志文章,多中心研究
doi:10.1002/acr.22451
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:Cognitive function may change over time in patients with SLE, and cognitive function trajectories have not well been studied. We aim to: 1) identify cognitive function trajectories in SLE and describe it with depressive symptoms trajectories and 2) identify baseline factors associated with class membership i...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.24349
更新日期:2020-06-11 00:00:00
abstract:OBJECTIVE:Children with juvenile idiopathic arthritis (JIA) experience functional impairment due to joint manifestations of the disease. The aim of our present study was to assess health-related quality of life (HRQOL) and its predictors in a group of children and adolescents with JIA. METHODS:The study sample include...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.21609
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:Two surveys were conducted with patients with rheumatologic diseases to evaluate perceptions of different routes of administration (intravenous [IV] or subcutaneous [SC]) for biologic therapy. METHODS:In Survey I, patient preferences toward biologic treatment were evaluated at a rheumatology practice in Buff...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.23758
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:To develop and pilot test a screening tool to identify cases of nephrogenic systemic fibrosis (NSF) among patients exposed to gadolinium-containing contrast agents. METHODS:Sixty English-speaking subjects were enrolled: 10 subjects diagnosed as having NSF, 10 subjects with other fibrosing skin diseases, 20 s...
journal_title:Arthritis care & research
pub_type: 临床试验,杂志文章
doi:10.1002/acr.21877
更新日期:2013-04-01 00:00:00
abstract:OBJECTIVE:This double-blind randomized controlled trial aimed to test the efficacy of self-administered acupressure for pain and physical function improvement for older adults with knee osteoarthritis (OA). METHODS:Participants were community-dwelling adults with symptomatic knee OA (n = 150, mean age 73 years), rando...
journal_title:Arthritis care & research
pub_type: 杂志文章,随机对照试验
doi:10.1002/acr.23262
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVE:To study how corticosteroid therapy is planned and described in reports of systemic disease trials and estimate the impact of the between-arm difference in corticosteroid dose on treatment effect. METHODS:We performed a systematic review of PubMed and Cochrane databases on all reports of randomized systemic ...
journal_title:Arthritis care & research
pub_type: 杂志文章,评审
doi:10.1002/acr.20139
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVE:Reactivation of Mycobacterium tuberculosis infection is a major complication in patients treated with anti-tumor necrosis factor (anti-TNF) agents. We report on the 5 cases of active tuberculosis (TB) that developed in the Golimumab Phase III Program (3 with rheumatoid arthritis, 1 with psoriatic arthritis, a...
journal_title:Arthritis care & research
pub_type: 杂志文章,随机对照试验
doi:10.1002/acr.21788
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVE:Total knee replacement (TKR) is an effective treatment for end-stage knee osteoarthritis (OA). American racial minorities undergo fewer TKRs than whites. We estimated quality-adjusted life-years (QALYs) lost for African American knee OA patients due to differences in TKR offer, acceptance, and complication ra...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.23484
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVE:Cachexia is a disorder characterized by involuntary weight loss in addition to loss of homeostatic control of both energy and protein balance. Despite an abundance of data from other inflammatory diseases, cachexia in SLE remains a largely undescribed syndrome. METHODS:2406 patients in a prospective SLE coho...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.24395
更新日期:2020-08-02 00:00:00
abstract:OBJECTIVE:To determine the prevalence, incidence, and burden of gout in the Veterans Health Administration (VHA) from 2005-2014. METHODS:We used national VHA data from 1/1999-12/2014 to determine the annual incidence and prevalence of gout in the VHA. Gout burden to the VHA was determined by the proportion of patients...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.24339
更新日期:2020-05-31 00:00:00
abstract:OBJECTIVE:To summarize the potential predictors of remission in patients with rheumatoid arthritis (RA). METHODS:We performed a systematic review of prognostic studies that identified the predictors of remission in RA patients. Studies were identified in Medline, EMBase, and the Cochrane Registry, and by hand search. ...
journal_title:Arthritis care & research
pub_type: 杂志文章,评审
doi:10.1002/acr.20188
更新日期:2010-08-01 00:00:00
abstract:OBJECTIVE:To develop and internally validate risk models and a clinical risk score tool to predict incident radiographic knee osteoarthritis (RKOA) in middle-aged women. METHODS:We analyzed 649 women in the Chingford 1,000 Women study. The outcome was incident RKOA, defined as Kellgren/Lawrence grade 0-1 at baseline a...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.23932
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:To assess the relative effectiveness of combining self-management and strength training for improving functional outcomes in patients with early knee osteoarthritis. METHODS:We conducted a randomized intervention trial lasting 24 months at an academic medical center. Community-dwelling middle-aged adults (n ...
journal_title:Arthritis care & research
pub_type: 杂志文章,随机对照试验
doi:10.1002/acr.20013
更新日期:2010-01-15 00:00:00
abstract:OBJECTIVE:To establish the impact of uveitis on the quality of life (QoL) in adult patients with juvenile idiopathic arthritis (JIA). METHODS:Adult patients with a history of JIA, both with (n = 31) or without (n = 51) chronic anterior uveitis, were included. Their scores on 3 validated QoL questionnaires (National Ey...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.23224
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:To compare the performances of 3 comorbidity indices, the Charlson Comorbidity Index, the Elixhauser Comorbidity Index, and the Centers for Medicare & Medicaid Services (CMS) risk adjustment model, Hierarchical Condition Category (HCC), in predicting post-acute discharge settings and hospital readmission for ...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.23195
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVES:Fatigue is common among people with inflammatory arthritis but is hard to manage. The aim of this study was to investigate how daily fluctuations in psychological variables correspond with changes in fatigue-related disability in the daily lives of people with inflammatory arthritis to identify factors to ta...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.24224
更新日期:2020-04-27 00:00:00
abstract:OBJECTIVE:To compare educational and vocational outcomes among adults with childhood-onset systemic lupus erythematosus (SLE) and adult-onset SLE. METHODS:We used data derived from the 2002–2010 cycles of the Lupus Outcomes Study, a longitudinal cohort of 1,204 adult subjects with SLE. Subjects ages 18–60 years living...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.22228
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVE:To comprehensively evaluate the performance of the Assessment of Quality of Life (AQoL) instrument for measuring health-related quality of life (HRQOL) in people with hip and knee joint disease (arthritis or osteoarthritis). METHODS:Data from 237 individuals were available for analysis from a national cross-...
journal_title:Arthritis care & research
pub_type: 临床试验,杂志文章
doi:10.1002/acr.22129
更新日期:2014-03-01 00:00:00
abstract:OBJECTIVE:We have previously reported increased long-term morbidity in children of parents with rheumatoid arthritis (RA). Here we assess child mortality and case fatality in the same cohort. METHODS:All singletons born in Denmark from 1977 to 2008 were identified through linkage of Danish national registries. Cox pro...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.22991
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of muscle strength exercise training (MSET) on lean mass (LM) gain and muscle hypertrophy in older patients with lower extremity osteoarthritis (OA). METHODS:A comprehensive search of online databases was performed on April 20, 2019. Randomized controlled trials (RCTs) that reported...
journal_title:Arthritis care & research
pub_type: 杂志文章,meta分析
doi:10.1002/acr.24097
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVE:Prior studies have established disparities by race/ethnicity and socioeconomic status (SES) in the kind, quantity, and technical quality of systemic lupus erythematosus (SLE) care and outcomes. In this study we evaluate whether disparities exist in assessments of interactions with health care providers and he...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.22427
更新日期:2015-03-01 00:00:00
abstract:OBJECTIVE:To assess the long-term outcome in eosinophilic granulomatosis with polyangiitis (Churg-Strauss) (EGPA). METHODS:A total of 101 patients fulfilling the American College of Rheumatology criteria for EGPA were included between 1990 and 2011. Clinical features, antineutrophil cytoplasm autoantibodies (ANCAs), a...
journal_title:Arthritis care & research
pub_type: 杂志文章,多中心研究
doi:10.1002/acr.22686
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVE:To determine the impact of stopping tumor necrosis factor inhibitor (TNFi) treatment on patient-reported outcomes (PROs) of physical and mental health status, health utility, pain, disability, and fatigue in patients with established rheumatoid arthritis (RA). METHODS:In the pragmatic, 12-month POET trial, 8...
journal_title:Arthritis care & research
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/acr.23315
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVE:To examine the temporal and dose-related effects of glucocorticoids (GCs) on body mass index (BMI) in children with rheumatic diseases. METHODS:Children initiating GCs for a rheumatic disease (n = 130) were assessed every 3 months for 18 months. BMI, weight, and height Z score trajectories were described acc...
journal_title:Arthritis care & research
pub_type: 杂志文章,多中心研究
doi:10.1002/acr.21785
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:To investigate cross-sectional and longitudinal associations of diffuse idiopathic skeletal hyperostosis (DISH) and thoracic kyphosis in older persons. METHODS:DISH and kyphosis were assessed in 1,500 men from the Osteoporotic Fractures in Men (MrOS) study and in 1,267 women from the Study of Osteoporotic Fr...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.23115
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:Despite the high prevalence of depression among vulnerable Hispanics with rheumatoid arthritis (RA), many do not disclose it or seek treatment. This study explored patient perceptions of depression, its association with their primary disease, barriers to disclosure, reasons for low utilization of mental healt...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.22462
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE:To determine whether there is a temporal association between arthritis and uveitis activity among children with juvenile idiopathic arthritis-associated uveitis (JIA-U). METHODS:Uveitis and arthritis data from JIA-U patients ≤21 years were collected from 7/2013-12/2019 at a tertiary care center. Arthritis ac...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.24483
更新日期:2020-10-12 00:00:00
abstract:OBJECTIVE:Health information technology (HIT) holds promise in increasing access to rheumatologists by improving the quality and efficiency of referrals, but few studies have examined its use for this purpose. We evaluated the use and impact of a novel electronic referral (eReferral) system in rheumatology in a safety-...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.22559
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVE:Concerns about SARS-CoV-2 infection may have led to changes or discontinuation of immunosuppressive medications among patients with systemic rheumatic disease. Our goal was to assess patients' perspectives regarding medication modifications and deviations from planned uses during the height of the pandemic. ...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.24489
更新日期:2020-10-21 00:00:00