Abstract:
OBJECTIVE:To determine the prevalence, incidence, and burden of gout in the Veterans Health Administration (VHA) from 2005-2014. METHODS:We used national VHA data from 1/1999-12/2014 to determine the annual incidence and prevalence of gout in the VHA. Gout burden to the VHA was determined by the proportion of patients with an encounter related to gout. Rates of urate lowering therapy (ULT) and opiate use were determined annually. Characteristics of those with and without gout were compared using 2014 data. RESULTS:From 2005 to 2014, gout prevalence in the VHA increased from 4.2% to 5.8% while disease incidence ranged from 5.8 to 7.4 cases per 1000 patient-years. Gout prevalence was highest among men, older patients, and non-Hispanic blacks. During 2014, 4.0% of all inpatient or outpatient encounters and 1.3% of hospitalizations were gout-related. ULT administration remained stable over the ten-year period, with 46% of gout patients receiving ULT in 2014. In contrast, 16.4% of prevalent gout patients were receiving a weak opioid in 2014, nearly doubling the prescription rate of weak opioids in 2005 while the use of stronger opioids did not change significantly over this period. Patients with gout had greater comorbidity and healthcare utilization than patients without gout. CONCLUSION:The burden posed by gout in the VHA is considerable and increased between 2005 and 2014. While the use of ULT has remained stable, the use of opioid therapy has increased among patients with gout.
journal_name
Arthritis Care Res (Hoboken)journal_title
Arthritis care & researchauthors
Helget LN,England BR,Roul P,Sayles H,Petro AD,Michaud K,Mikuls TRdoi
10.1002/acr.24339subject
Has Abstractpub_date
2020-05-31 00:00:00eissn
2151-464Xissn
2151-4658pub_type
杂志文章abstract:OBJECTIVE:Joint replacement surgery is a proxy of severe joint damage in rheumatoid arthritis (RA). The aim of this study was to assess the impact of the introduction of biologic disease-modifying antirheumatic drugs (bDMARDs) on the incidence rate (IR) of upper limb joint replacements among newly diagnosed RA patients...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.23835
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVE:The influence of specific medications on the risk of postoperative infection in patients with rheumatoid arthritis and other inflammatory rheumatic diseases (IRDs) remains unclear. This retrospective study examined the risk of postoperative infection at the site of surgery in patients treated with immunosuppr...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.22077
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:Prior studies have established disparities by race/ethnicity and socioeconomic status (SES) in the kind, quantity, and technical quality of systemic lupus erythematosus (SLE) care and outcomes. In this study we evaluate whether disparities exist in assessments of interactions with health care providers and he...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.22427
更新日期:2015-03-01 00:00:00
abstract:OBJECTIVE:To assess the association of specific comorbidities with periprosthetic fractures after primary total knee replacement (TKR). METHODS:We used the prospectively collected data in the Mayo Clinic total joint registry from 1989-2008 on all patients who had undergone primary TKR. The outcome of interest was post...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.20548
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVE:To evaluate time trends in mortality for hospitalized adults with systemic lupus erythematosus (SLE) compared to the general hospitalized population (GHP), and to identify factors associated with increased risk of death among hospitalized SLE patients. METHODS:We used the National (Nationwide) Inpatient Samp...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.24356
更新日期:2020-06-17 00:00:00
abstract:OBJECTIVE:Independent investigations have shown that socioeconomic status (SES) and learned helplessness (LH) are associated with poor disease outcome in patients with rheumatoid arthritis (RA). Our aim was to investigate the cross-sectional relationship between SES, LH, and disease outcome in patients with recent-onse...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.21677
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVE:Early detection and preemptive treatment of patients at risk is of great importance in reducing the excess risk of cardiovascular (CV) disease in rheumatoid arthritis (RA). However, it is unclear how much screening is cost-effective in RA. The objective is to assess whether CV screening in RA proves to be cos...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.22929
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVE:To examine the association between weight change from young adulthood to midlife and risk of incident arthritis. METHODS:Using data from the National Health and Nutrition Examination Survey (NHANES), we categorized participants into weight change categories based on their recalled weight during young adultho...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.24252
更新日期:2020-05-06 00:00:00
abstract:OBJECTIVE:To describe the effect of different exposure classification strategies for disease-modifying antirheumatic drugs (DMARDs) on drug-outcome associations. METHODS:We studied the association between DMARD initiation and all-cause hospitalizations in patients with rheumatoid arthritis (RA), 1995-2005. Initiators ...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.20087
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVE:To examine the external validity of the Lupus Impact Tracker (LIT), a systemic lupus erythematosus (SLE)-specific, health-related quality of life (HRQoL) tool in a population-based cohort of patients with SLE in Atlanta, Georgia. We modeled the association of LIT scores with patient-reported measures of SLE a...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.23009
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:Several current and many emerging osteoarthritis (OA) treatments are intra-articular (IA) injections. However, little is known about physicians' perceptions and beliefs regarding IA injections or their considerations when deciding whether to recommend them to patients. We aimed to investigate physician-percei...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.24502
更新日期:2020-11-09 00:00:00
abstract:OBJECTIVE:To assess the frequency of fibromyalgia syndrome (FMS), depression, and sleep disorders in patients with granulomatosis with polyangiitis (Wegener's) (GPA). METHODS:The London Fibromyalgia Epidemiologic Study Screening Questionnaire (LFESSQ), Symptom Intensity Scale, Epworth Sleepiness Scale (ESS), and the B...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.20442
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVE:We aimed to determine if there were sex differences in lean body mass (LBM) in patients with rheumatoid arthritis (RA) when compared with sex- and race-specific National Health and Nutrition Examination Survey (NHANES) reference data, and to investigate the impact of sex differences in risk factors for LBM de...
journal_title:Arthritis care & research
pub_type: 杂志文章,多中心研究
doi:10.1002/acr.22396
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:To characterize the cutaneous and systemic clinical phenotype of dermatomyositis patients with antinuclear matrix protein 2 (anti-NXP-2) antibodies. METHODS:We conducted a retrospective cohort analysis of 178 dermatomyositis patients seen at the Stanford University Clinic. An electronic chart review employin...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.23210
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:To estimate the prevalence of overweight and obese Canadians with arthritis and to describe their use of arthritis self-management strategies, as well as explore the factors associated with not engaging in any self-management strategies. METHODS:Respondents to the 2009 Survey on Living with Chronic Diseases ...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.20654
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVE:Systemic lupus erythematosus (SLE) predominantly affects women. Clinical phenotype and outcomes in SLE may vary by sex and are further complicated by unique concerns that are dependent upon sex-defined roles. We aimed to describe sex differences in disease-specific quality of life (QoL) assessment scores usin...
journal_title:Arthritis care & research
pub_type: 杂志文章,多中心研究
doi:10.1002/acr.23588
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVE:To describe the experiences and strategies of employees with arthritis to maintain employment, and to use this information to build a conceptual model. METHODS:We conducted a systematic review of qualitative studies that examined the work experiences of employees with arthritis. Published studies on arthriti...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.23528
更新日期:2018-11-01 00:00:00
abstract:OBJECTIVE:To assess the impact of weekly text messages on adherence in patients taking methotrexate (MTX) for rheumatoid arthritis (RA). METHODS:This prospective, randomized pilot, single-site study included patients with RA stabilized using MTX alone or combined with biologics. Participants were randomized to 3 inter...
journal_title:Arthritis care & research
pub_type: 杂志文章,随机对照试验
doi:10.1002/acr.23750
更新日期:2019-10-01 00:00:00
abstract:OBJECTIVE:To evaluate if exercise programs in trials for patients with ankylosing spondylitis (AS) have the potential for effectiveness. METHODS:A systematic literature search was performed and randomized trials examining the effectiveness of exercise programs for AS patients were analyzed according to 3 elements: whe...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.20415
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVE:To examine temporal trends in mortality rates in a large nationwide cohort of patients with end-stage renal disease (ESRD) due to granulomatosis with polyangiitis (Wegener's) (GPA-ESRD). METHODS:We identified cases of GPA-ESRD reported in the US Renal Data System between 1995 and 2014, using coding by nephro...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.23521
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVE:To investigate differences in EMG muscle activity and scapular kinematics during elevation in the scapular plane between healthy controls, participants with multidirectional shoulder laxity (MDL), and patients with multidirectional shoulder instability (MDI) who are diagnosed with hypermobile Ehlers-Danlos sy...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.24525
更新日期:2020-11-30 00:00:00
abstract:OBJECTIVE:The availability of reliable estimates of the burden of musculoskeletal disease is of considerable importance for policymakers. METHODS:This study uses data from the 14,507 participants of the European Health Interview Survey conducted in Austria in 2006/2007 to calculate estimates of the prevalence of osteo...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.20558
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVE:Disease activity measured by validated methods has been sparsely examined during and after pregnancy in women with systemic lupus erythematosus (SLE). The aim of this study was to describe the longitudinal course of disease activity during pregnancy and the first year postpartum using the Lupus Activity Index...
journal_title:Arthritis care & research
pub_type: 杂志文章,多中心研究
doi:10.1002/acr.23102
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:To compare 3 methods for calculating the Bath Ankylosing Spondylitis Metrology Index (BASMI) score using patients who participated in the GO-RAISE study. METHODS:Patients with active ankylosing spondylitis (AS) were randomly assigned in a 1:1.8:1.8 ratio to receive subcutaneous injections of placebo, golimum...
journal_title:Arthritis care & research
pub_type: 杂志文章,随机对照试验
doi:10.1002/acr.21771
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:To establish the impact of uveitis on the quality of life (QoL) in adult patients with juvenile idiopathic arthritis (JIA). METHODS:Adult patients with a history of JIA, both with (n = 31) or without (n = 51) chronic anterior uveitis, were included. Their scores on 3 validated QoL questionnaires (National Ey...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.23224
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:To assess health-related quality of life (HRQOL) in abatacept-treated children/adolescents with juvenile idiopathic arthritis (JIA). METHODS:In this phase III, double-blind, placebo-controlled trial, subjects with active polyarticular course JIA and an inadequate response/intolerance to ≥1 disease-modifying ...
journal_title:Arthritis care & research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/acr.20283
更新日期:2010-11-01 00:00:00
abstract:OBJECTIVE:To systematically review evidence of the impact of inflammatory arthritis on, or association of inflammatory arthritis with, intimate relationships and sexual function. METHODS:Ovid Medline, Ovid PsycINFO, Ovid Embase, and EBSCO CINAHL databases were searched. Two independent reviewers selected articles, ext...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.23857
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:Hydroxychloroquine (HCQ) has been associated with improved survival among SLE patients from tertiary referral centers. We aimed to determine the potential impact of HCQ use on the risk of mortality among SLE patients in the general population. METHODS:We conducted a nested case-control study within an incide...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.24255
更新日期:2020-05-14 00:00:00
abstract:OBJECTIVE:To assess the association of femoroacetabular impingement (FAI) and delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) T1 relaxation values (RVs), and to evaluate whether subtypes of FAI (cam, pincer, and mixed) are associated with region-specific dGEMRIC T1 RVs. METHODS:A populati...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.23463
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVE:To describe long-term physical functioning and its association with somatic comorbidity and comorbid depression in patients with established rheumatoid arthritis (RA). METHODS:Longitudinal data over a period of 11 years were collected from 882 patients with RA at study inclusion. Patient-reported outcomes we...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.21950
更新日期:2013-07-01 00:00:00