A 5-yr follow-up nerve conduction study for the detection of subclinical diabetic neuropathy in children with newly diagnosed insulin-dependent diabetes mellitus.

abstract：:Despite the increased prevalence of type 2 diabetes mellitus (T2DM) in the pediatric population, there is limited information about the relative effectiveness of treatment approaches. This article describes the rationale and design of a National Institutes of Health-sponsored multi-site, randomized, parallel group cli...

journal_title：Pediatric diabetes

authors： TODAY Study Group.,Zeitler P,Epstein L,Grey M,Hirst K,Kaufman F,Tamborlane W,Wilfley D

更新日期：2007-04-01 00:00:00

abstract：:The Juvenile Diabetes Research Foundation International (JDRF) was founded in 1970 by parents of children with juvenile diabetes to find a cure for diabetes and its complications through the support of research. The foundation was an early supporter of stem cell research, recognizing the promise of stem cells to quick...

journal_title：Pediatric diabetes

authors： Nierras CR,Stallard J,Goldstein RA,Insel R

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:To investigate carbohydrate (CARB) and supplementary fat/protein (CFP) counting using normal and dual-wave bolus in pump therapy of children and young people with type 1 diabetes (T1D). STUDY DESIGN AND METHODS:A randomized clinical trial was conducted in 42 patients (age 6-21 yr) with T1D for at least 1 yr ...

journal_title：Pediatric diabetes

authors： Kordonouri O,Hartmann R,Remus K,Bläsig S,Sadeghian E,Danne T

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Previous studies have reported that handgrip strength, a measure of muscular fitness, is associated with insulin resistance in children and adolescents, with conflicting results. Further, no studies have examined the association between handgrip strength with 2-hour glucose levels. OBJECTIVE:We tested the a...

journal_title：Pediatric diabetes

authors： Li S,Zhang R,Pan G,Zheng L,Li C

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Non-alcoholic fatty liver disease (NAFLD) is a comorbidity of childhood obesity. OBJECTIVE:We examined whole-body substrate metabolism and metabolic characteristics in obese adolescents with vs. without NAFLD. SUBJECTS:Twelve obese (BMI ≥ 95th percentile) adolescents with and without NAFLD [intrahepatic tr...

journal_title：Pediatric diabetes

authors： Lee S,Rivera-Vega M,Alsayed HM,Boesch C,Libman I

更新日期：2015-05-01 00:00:00

abstract：AIMS:The cardiovascular risk factor profile of a child as well as the development of body weight are influenced by genetic and childhood factors. Circulating insulin concentrations reflect the metabolic cardiovascular risk and may trigger weight gain. We aimed at identifying parental and childhood factors which may inf...

journal_title：Pediatric diabetes

authors： Brandt S,Moß A,Lennerz B,Koenig W,Weyermann M,Rothenbacher D,Brenner H,Wabitsch M

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to evaluate the effectiveness of directly integrating self-monitoring blood glucose (BG) information with insulin pump therapy on overall glycemic control. METHODS:In this randomized trial, 34 youth with type 1 diabetes using insulin pump therapy were trained on the use of the ...

journal_title：Pediatric diabetes

authors： Cobry E,Chase HP,Burdick P,McFann K,Yetzer H,Scrimgeour L

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVE:To describe insulin pump use by youth since introduction of universal funding in Ontario, Canada and to explore the relationship between pump use and pediatric diabetes center characteristics and the relationship between discontinuation and center and patient characteristics. RESEARCH DESIGN AND METHODS:Obse...

journal_title：Pediatric diabetes

authors： Shulman R,Stukel TA,Miller FA,Newman A,Daneman D,Guttmann A

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:The prevalence of macrovascular complications is probably underestimated in children with type 1 diabetes (T1D). Arterial stiffness (AS) is a subclinical marker of cardiovascular (CV) risk. The most validated, non-invasive method for AS measurement is pulse wave velocity (PWV). Only a few PWV studies have be...

journal_title：Pediatric diabetes

authors： Obermannova B,Petruzelkova L,Sulakova T,Sumnik Z

更新日期：2017-06-01 00:00:00

abstract：:The extant literature finds that children with type 1 diabetes mellitus (T1D) experience mild cognitive alterations compared to healthy age-matched controls. The neural basis of these cognitive differences is unclear but may relate in part to the effects of dysglycemia on the developing brain. We investigated longitud...

journal_title：Pediatric diabetes

authors： Foland-Ross LC,Reiss AL,Mazaika PK,Mauras N,Weinzimer SA,Aye T,Tansey MJ,White NH,Diabetes Research in Children Network (DirecNet).

更新日期：2018-04-19 00:00:00

abstract：BACKGROUND:The autoimmune destruction of beta cells, resulting in clinical type 1 diabetes, may start early in life and last for several months or years. During this period of time, we have an opportunity to try to prevent or delay further beta-cell destruction and clinical onset of type 1 diabetes. OBJECTIVES:Ongoing...

journal_title：Pediatric diabetes

authors： Elding Larsson H

更新日期：2016-07-01 00:00:00

abstract：AIM:To explore racial differences in adiponectin, and leptin and their relationship with islet autoimmunity in children with new-onset type 1 diabetes (T1D). METHODS:Medical records were reviewed from a cohort of new-onset clinically diagnosed T1D subjects matched by race, age, gender, and year of diagnosis. Sera were...

journal_title：Pediatric diabetes

authors： Hecht Baldauff N,Tfayli H,Dong W,Arena VC,Gurtunca N,Pietropaolo M,Becker DJ,Libman IM

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVES:To assess the ability of reactive hyperemia-peripheral artery tonometry (RH-PAT) to serve as a surrogate marker of endothelial dysfunction in children with type 1 diabetes (T1D). RESEARCH DESIGN AND METHODS:Forty-four children with T1D [age 14.6 +/- 2.7 yr; duration of diabetes 6.01 +/- 4 yr; range of diabe...

journal_title：Pediatric diabetes

authors： Haller MJ,Stein J,Shuster J,Theriaque D,Silverstein J,Schatz DA,Earing MG,Lerman A,Mahmud FH

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVE:The Environmental Determinants of Diabetes in the Young (TEDDY) study is designed to identify environmental exposures triggering islet autoimmunity and type 1 diabetes (T1D) in genetically high-risk children. We describe the first 100 participants diagnosed with T1D, hypothesizing that (i) they are diagnosed ...

journal_title：Pediatric diabetes

authors： Elding Larsson H,Vehik K,Gesualdo P,Akolkar B,Hagopian W,Krischer J,Lernmark Å,Rewers M,Simell O,She JX,Ziegler A,Haller MJ,TEDDY Study Group.

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:This study aimed to determine the degree of left ventricular (LV) dysfunction and its determinants in adolescents with type 2 diabetes (T2D). We hypothesized that adolescents with T2D would display impaired LV diastolic function and that these cardiovascular complications would be exacerbated in youth exposed...

journal_title：Pediatric diabetes

authors： Guillemette L,Dart A,Wicklow B,Dolinsky VW,Cheung D,Jassal DS,Sellers EAC,Gelinas J,Eves ND,Balshaw R,Agarwal P,Duhamel TA,Gordon JW,McGavock JM

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:To examine the extent to which self-regulation skills of adolescents with type 1 diabetes (T1D), including executive functioning and emotion regulation, relate to treatment adherence and glycemic control. METHOD:Participants were 109 adolescents aged 12-18 yr with TID and their primary caregiver who attended...

journal_title：Pediatric diabetes

authors： Graziano PA,Geffken GR,Williams LB,Lewin AB,Duke DC,Storch EA,Silverstein JH

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:To investigate if maternal diet during pregnancy is associated with occurrence of islet autoimmunity (IA) in the offspring. METHODS:Of 21 700 infants invited to the All Babies in South-east Sweden (ABIS) study, 16 004 screening questionnaires, including a 22-item food frequency questionnaire (FFQ) regarding ...

journal_title：Pediatric diabetes

authors： Brekke HK,Ludvigsson J

更新日期：2010-06-01 00:00:00

abstract：AIM:To report C-peptide results in newly diagnosed patients and the relation to clinical diagnosis of diabetes. METHODS:A nation-wide cohort, the Better Diabetes Diagnosis study was used to determine serum C-peptide at diagnosis in 2734 children and adolescents. Clinical data were collected at diagnosis and follow-up....

journal_title：Pediatric diabetes

authors： Ludvigsson J,Carlsson A,Forsander G,Ivarsson S,Kockum I,Lernmark A,Lindblad B,Marcus C,Samuelsson U

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Few diabetes-specific quality of life (QOL) tools are available for young children. OBJECTIVES:To design and evaluate, a new age-specific QOL questionnaire and its associations with treatment regimens and metabolic control. METHODS:Clinical, demographic data and centrally analyzed HbA1c were collected on 1...

journal_title：Pediatric diabetes

authors： Hoey H,Lange K,Skinner TC,Mortensen H,Swift P,Aanstoot HJ,Castaňo L,Cameron F,de Beaufort C,Hvidoere International Study Group.

更新日期：2018-05-01 00:00:00

abstract：:Neonatal diabetes mellitus is rare, may either be transient or permanent, and may be caused by mutations in any of the several different genes. Until recently, most forms of permanent neonatal diabetes required lifelong subcutaneous insulin for management; however, permanent neonatal diabetes due to activating mutatio...

journal_title：Pediatric diabetes

authors： Bremer AA,Ranadive S,Lustig RH

更新日期：2008-06-01 00:00:00

abstract：AIMS:To design, develop, and evaluate the feasibility of delivering a multi-component community based intervention to parents and primary health care professionals to raise awareness of the symptoms of Type 1 diabetes (T1D) in childhood in 3 adjoining borough counties of South Wales. MATERIALS AND METHODS:Parent and p...

journal_title：Pediatric diabetes

authors： Townson J,Gregory JW,Cowley L,Gallagher D,Channon S,Robling M,Williams D,Hughes C,Murphy S,Lowes L

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Dominant inactivating mutations in HNF1A and HNF4A have been described to cause hyperinsulinism (HI) before evolving to diabetes. However, information available in the literature regarding the clinical phenotype is limited. OBJECTIVE:To report the prevalence of HNF1A and HNF4A mutations in a large cohort of...

journal_title：Pediatric diabetes

authors： Tung JY,Boodhansingh K,Stanley CA,De León DD

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:To compare the aerobic exercise capacity between normal adolescents and those with type 1 diabetes mellitus (T1DM). METHODS:An experimental group with 72 individuals diagnosed with T1DM aged 9--20, time from diagnosis 4.9 +/- 3.6 yr, without clinical cardiopulmonary disease or anemia and a control group (C) ...

journal_title：Pediatric diabetes

authors： Komatsu WR,Gabbay MA,Castro ML,Saraiva GL,Chacra AR,de Barros Neto TL,Dib SA

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Insulin deficiency with glucagon excess leads to the release of ketone bodies (KBs) by the liver and excretion in the urine. So far, only KB monitoring in urine has been used during assessment of children with diabetes. Currently used nitroprusside strips for urine KB detection react only with acetoacetate (...

journal_title：Pediatric diabetes

authors： Prisco F,Picardi A,Iafusco D,Lorini R,Minicucci L,Martinucci ME,Toni S,Cerutti F,Rabbone I,Buzzetti R,Crino A,Pozzilli P

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVE:To explore the outcomes of monthly video consultations for children with diabetes. METHODS:The Virtual Outpatient Diabetes Clinic for Children and Youth (VIDIKI) was a 6-month multicenter controlled clinical trial followed by an extension phase. The 240 participants (1-16 years), all using a CGM, were quasi-...

journal_title：Pediatric diabetes

authors： von Sengbusch S,Eisemann N,Mueller-Godeffroy E,Lange K,Doerdelmann J,Erdem A,Menrath I,Bokelmann J,Krasmann M,Kaczmarczyk P,Bertram B,Hiort O,Katalinic A,Frielitz FS

更新日期：2020-12-01 00:00:00

abstract：:Because amylin is co-secreted with insulin from beta cells, patients with type 1 diabetes (T1DM) are deficient in both insulin and amylin. Amylin delays gastric emptying and suppresses glucagon in the postprandial period. Hence, we hypothesized that children with complication-naive T1DM have accelerated gastric emptyi...

journal_title：Pediatric diabetes

authors： Heptulla RA,Rodriguez LM,Mason KJ,Haymond MW

更新日期：2008-12-01 00:00:00

abstract：:In connection with the article entitled "A randomized trial comparing the rate of hypoglycemia – assessed using continuous glucose monitoring – in 125 preschool children with type 1 diabetes treated with insulin glargine or NPH insulin (the PRESCHOOL study)" which appeared in [1], we wish to bring the following correc...

journal_title：Pediatric diabetes

authors：

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Care for children and youth with diabetes varies markedly around the world. We developed a standardized, reproducible measure that can be used to document and compare critical factors influencing treatment outcomes. METHODS:A questionnaire consisting of 36 multiple-choice questions covering m...

journal_title：Pediatric diabetes

authors： Ogle GD,Middlehurst AC,Silink M

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:In the non-diabetic population, intramyocellular lipid (IMCL) accumulation is associated with obesity and poor muscle oxygen supply. IMCL levels are increased in type 1 diabetes, but their significance is less clear. METHODS:We studied a group of 16 prepubertal boys (age 6.4-9.9 yr) with type 1 diabetes and...

journal_title：Pediatric diabetes

authors： Ling AH,Donaghue KC,Howard NJ,Arrowsmith FE,Ward JA,Baur LA,Thompson CH

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Hypoglycemia is the most common and severe complication of insulin treatment during the management of type 1 diabetes mellitus (T1DM). Despite its importance, there is a lack of data about the efficacy and superiority of the carbohydrate sources used in hypoglycemia management in children and adolescents. O...

journal_title：Pediatric diabetes

authors： Erbas IM,Abaci A,Anik A,Simsek E,Tuhan HU,Kocyigit C,Yıldız M,Dundar BN,Bober E,Catli G

更新日期：2020-07-13 00:00:00