Peripheral artery tonometry demonstrates altered endothelial function in children with type 1 diabetes.

abstract：:Hypoglycemia is an inevitable consequence of the treatment of type 1 diabetes in childhood. Nocturnal hypoglycemia is often considered as merely the submerged part of this serious complication yet there are reasons to believe that hypoglycemia occurring during sleep may be different in physiological terms. Glucose hom...

journal_title：Pediatric diabetes

authors： Matyka KA

更新日期：2002-06-01 00:00:00

abstract：AIM:The aim of this study was to compare genetic (HLA-DQ) and immune markers in a large population of type 1 diabetic (T1D) children and adolescents residing in the same environment, but of different ethnic origin: European Caucasians (EC), Moghrabin Caucasians (MC), Black Africans (BA) and of Mixed Origin (MO). METHO...

journal_title：Pediatric diabetes

authors： Stoupa A,Dorchy H

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Several intervention studies have convincingly demonstrated the importance of good glycemic control to avoid long-term diabetic complications, but the importance of other risk factors remains controversial. We previously reported a markedly reduced incidence of severe retinopathy and nephropathy during the p...

journal_title：Pediatric diabetes

authors： Nordwall M,Arnqvist HJ,Bojestig M,Ludvigsson J

更新日期：2009-05-01 00:00:00

abstract：:Activating mutations in the K(ATP)-channel cause neonatal diabetes mellitus (NDM), and patients have been safely transitioned from insulin to sulfonylureas. We report a male infant with permanent NDM (PNDM), born to a PNDM mother. Blood glucose began to rise on day of life (DOL) 2, and sulfonylurea (glyburide) therapy...

journal_title：Pediatric diabetes

authors： Wambach JA,Marshall BA,Koster JC,White NH,Nichols CG

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:It is unknown whether measurement site of visceral adipose tissue (VAT) influences the relationship between VAT and associated health risk in youth and if so, whether ethnic differences exist in this relationship. We examined the influence of the measurement site of VAT on the relationships between VAT and me...

journal_title：Pediatric diabetes

authors： Lee S,Kuk JL,Kim Y,Arslanian SA

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:There are substantial controversies about the clinical utility of adolescent metabolic syndrome (MetS). The current study examined the stability of adolescent MetS by assessing the agreement and discriminative abilities of four different definitions of adolescent MetS and the adult MetS definit...

journal_title：Pediatric diabetes

authors： Asghari G,Eftekharzadeh A,Hosseinpanah F,Ghareh S,Mirmiran P,Azizi F

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Children who inject insulin need clear guidelines as to the length of needle best for them. We studied the distance from surface to muscle in children in order to make needle choices which are evidence-based. METHODS:One hundred one children with type 1 diabetes were divided into three groups according to a...

journal_title：Pediatric diabetes

authors： Lo Presti D,Ingegnosi C,Strauss K

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Pediatric diabetes clinics around the world rapidly adapted care in response to COVID-19. We explored provider perceptions of care delivery adaptations and challenges for providers and patients across nine international pediatric diabetes clinics. METHODS:Providers in a quality improvement collaborative com...

journal_title：Pediatric diabetes

authors： Cristello Sarteau A,Souris KJ,Wang J,Ramadan AA,Addala A,Bowlby D,Corathers S,Forsander G,King B,Law JR,Liu W,Malik F,Pihoker C,Seid M,Smart C,Sundberg F,Tandon N,Yao M,Headley T,Mayer-Davis E

更新日期：2021-01-19 00:00:00

abstract：OBJECTIVE:To determine the HLA-DRB1, DQB1, DPB1, A, C, and B genotypes among Japanese children with autoimmune type 1 diabetes. METHODS:Four hundred and thirty patients who were GADAb and/or IA-2Ab-positive (Type 1A) were recruited from 37 medical centers as part of a nationwide multicenter collaborative study. DNA sa...

journal_title：Pediatric diabetes

authors： Sugihara S,Ogata T,Kawamura T,Urakami T,Takemoto K,Kikuchi N,Takubo N,Tsubouchi K,Horikawa R,Kobayashi K,Kasahara Y,Kikuchi T,Koike A,Mochizuki T,Minamitani K,Takaya R,Mochizuki H,Nishii A,Yokota I,Kizaki Z,Mori T

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Care for children and youth with diabetes varies markedly around the world. We developed a standardized, reproducible measure that can be used to document and compare critical factors influencing treatment outcomes. METHODS:A questionnaire consisting of 36 multiple-choice questions covering m...

journal_title：Pediatric diabetes

authors： Ogle GD,Middlehurst AC,Silink M

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:Restrictive eligibility criteria have hampered enrollment into trials for new drugs for youth with type 2 diabetes (T2D). We utilized Pediatric Diabetes Consortium (PDC) T2D Registry enrollment data to estimate the percentage of patients who would be excluded from current T2D trials based on out-of...

journal_title：Pediatric diabetes

authors： Tamborlane WV,Chang P,Kollman C,Klingensmith GJ,Ruedy K,Gal RL,Van Name M,Bacha F,Willi S,Beck RW,Pediatric Diabetes Consortium.

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:In the non-diabetic population, intramyocellular lipid (IMCL) accumulation is associated with obesity and poor muscle oxygen supply. IMCL levels are increased in type 1 diabetes, but their significance is less clear. METHODS:We studied a group of 16 prepubertal boys (age 6.4-9.9 yr) with type 1 diabetes and...

journal_title：Pediatric diabetes

authors： Ling AH,Donaghue KC,Howard NJ,Arrowsmith FE,Ward JA,Baur LA,Thompson CH

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Hemoglobin A1c (HbA1c) levels have been shown to worsen in adolescence and be related to long-term diabetes complications. Although categories of diabetes control (e.g., ideal, satisfactory, and poor) are routinely used in clinical practice, research has not fully explored whether these categories meaningful...

journal_title：Pediatric diabetes

authors： Kichler JC,Kaugars AS,Ellis J,Alemzadeh R

更新日期：2010-12-01 00:00:00

abstract：INTRODUCTION:The accuracy of blood pressure (BP) measurement is a prerequisite for the reliable diagnosis and management of hypertension. OBJECTIVES:This survey evaluated the use of office and out-of-office BP measurements and the antihypertensive pharmacological treatment in expert pediatric diabetes centers. METHOD...

journal_title：Pediatric diabetes

authors： Gerasimidi-Vazeou A,Birkebaek NH,Iotova V,Cherubini V,Piccini B,Biester T,Stipancic G,Jefferies C,Maffeis C,Stergiou GS,SWEET study group.

更新日期：2020-12-01 00:00:00

abstract：PURPOSE:To examine risk factors for re-hospitalization after diagnosis of diabetes mellitus amongst urban minority children. METHODS:Families of insulin-treated African-American and Latino patients aged < 18 yr at diagnosis (n = 216) were interviewed about sociodemographics and other characteristics, on average 5.9 yr...

journal_title：Pediatric diabetes

authors： Lipton RB,Zierold KM,Drum ML,Klein-Gitelman M,Kohrman AF

更新日期：2002-03-01 00:00:00

abstract：:Inactivating mutations in the pancreatic beta cell ATP-sensitive potassium (K(ATP) ) channel genes are identified by sequencing in approximately 80% of patients with diazoxide-unresponsive hyperinsulinaemic hypoglycaemia (HH). Genetic testing is clinically important as the mode of inheritance of a K(ATP) channel mutat...

journal_title：Pediatric diabetes

authors： Flanagan S,Damhuis A,Banerjee I,Rokicki D,Jefferies C,Kapoor R,Hussain K,Ellard S

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to investigate the importance of trust in researchers and other reasons that participating parents, former participants, and non-participants had for participating, or not participating, in a longitudinal cohort study on prediction and development of diabetes in children. STUD...

journal_title：Pediatric diabetes

authors： Helgesson G,Hansson MG,Ludvigsson J,Swartling U

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Teens with type 1 diabetes (T1D) experience increased sleep disturbances, which have been linked to problems with adherence and glycemic control. As such, sleep represents a novel target to improve outcomes in teens. OBJECTIVE:To evaluate the feasibility, acceptability, and preliminary efficacy of a sleep-p...

journal_title：Pediatric diabetes

authors： Jaser SS,Hamburger ER,Bergner EM,Williams R,Slaughter JC,Simmons JH,Malow BA

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVE:The metabolic syndrome is associated with insulin resistance in adults. We defined pediatric metabolic syndrome using criteria analogous to Adult Treatment Panel III. The purpose of this study was to determine whether these criteria are reliable for insulin resistance in children. RESEARCH DESIGN AND METHODS...

journal_title：Pediatric diabetes

authors： Hirschler V,Calcagno ML,Aranda C,Maccallini G,Jadzinsky M

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVES:We assessed pubertal development, height, weight, and waist-to-hip ratio (WHR), an index of central adiposity during puberty, in girls with type-1 diabetes mellitus (T1DM), compared to a contemporary control group. METHODS:Pubertal development, weight, height and WHR were studied in 100 pubertal girls with ...

journal_title：Pediatric diabetes

authors： Codner E,Barrera A,Mook-Kanamori D,Bazaes RA,Unanue N,Gaete X,Avila A,Ugarte F,Torrealba I,Pérez V,Panteón E,Cassorla F

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:The aim of the study was to search for mutations in the NEUROD1 and IPF-1 genes in patients with clinical characteristics of maturity-onset diabetes of the young (MODY) but with no mutations in the HNF-4A (MODY1), GCK (MODY2) and TCF1 (MODY3) genes. METHODS:We studied 30 unrelated Czech probands with a clin...

journal_title：Pediatric diabetes

authors： Gonsorcíková L,Průhová S,Cinek O,Ek J,Pelikánová T,Jørgensen T,Eiberg H,Pedersen O,Hansen T,Lebl J

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Adults with type 2 diabetes mellitus (T2DM) have broad impairments in beta-cell function, including severe attenuation of the first-phase insulin response to glucose, and reduced beta-cell mass. In adolescents with T2DM, there is some evidence that beta-cell dysfunction may be less severe. Our objective was ...

journal_title：Pediatric diabetes

authors： Elder DA,Woo JG,D'Alessio DA

更新日期：2010-08-01 00:00:00

abstract：:With the increasing success of islet transplantation, beta-cell replacement therapy has had renewed interest. To make such a therapy available to more than a few of the thousands of patients with diabetes, new sources of insulin-producing cells must become readily available. The most promising sources are stem cells, ...

journal_title：Pediatric diabetes

authors： Bonner-Weir S,Toschi E,Inada A,Reitz P,Fonseca SY,Aye T,Sharma A

更新日期：2004-01-01 00:00:00

abstract：:This review highlights the evidence of linking small for gestational age (SGA) with metabolic/cardiovascular disturbances (dysmetabolic syndrome) in later life. The metabolic and cardiovascular complications associated with in utero undernutrition have been identified during the past 10 yr. Reduced fetal growth is ind...

journal_title：Pediatric diabetes

authors： Levy-Marchal C,Jaquet D

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:To investigate the changes of peripheral nerve conduction in children with insulin-dependent diabetes mellitus (IDDM) prospectively from diagnosis and to know how those results were related to clinical risk factors. METHODS:A total of 37 patients (14 males and 23 females) aged 3-19 yr (mean 12.0 ± 3.7) with ...

journal_title：Pediatric diabetes

authors： Lee SS,Han HS,Kim H

更新日期：2010-12-01 00:00:00

abstract：:Regulatory T cells (Tregs) are responsible for the maintenance of peripheral tolerance. Animal studies have shown that administration of Tregs can prevent type 1 diabetes (DM1). Several clinical trials attempted to induce Tregs with various agents, and thus provide long-term tolerance of β cells in DM1. Nevertheless, ...

journal_title：Pediatric diabetes

authors： Marek-Trzonkowska N,Myśliwec M,Siebert J,Trzonkowski P

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:Most youth with type 1 diabetes do not meet the American Diabetes Association (ADA) and International Society for Pediatric and Adolescent Diabetes (ISPAD) targets for hemoglobin A1c (HbA1c), blood pressure (BP), lipids, and body mass index (BMI). We hypothesized that ISPAD/ADA goal achievement would be assoc...

journal_title：Pediatric diabetes

authors： Bjornstad P,Cree-Green M,Baumgartner A,Coe G,Reyes YG,Schäfer M,Pyle L,Regensteiner JG,Reusch JE,Nadeau KJ

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:To determine the roles of complement C4A and C4B gene copy-number variations and their plasma protein concentrations in residual insulin secretion and loss of pancreatic β-cell function in new-onset type 1 diabetes (T1D) patients. METHODS:We studied 34 patients of European ancestry with new-onset T1D, aged b...

journal_title：Pediatric diabetes

authors： Kingery SE,Wu YL,Zhou B,Hoffman RP,Yu CY

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:The primary objective of this trial was to evaluate the feasibility, safety, and efficacy of a predictive hyperglycemia and hypoglycemia minimization (PHHM) system vs predictive low glucose suspension (PLGS) alone in optimizing overnight glucose control in children 6 to 14 years old. RESEARCH DESIGN AND METH...

journal_title：Pediatric diabetes

authors： Forlenza GP,Raghinaru D,Cameron F,Wayne Bequette B,Peter Chase H,Paul Wadwa R,Maahs DM,Jost E,Ly TT,Wilson DM,Norlander L,Ekhlaspour L,Min H,Clinton P,Njeru N,Lum JW,Kollman C,Beck RW,Buckingham BA,In-Home Closed-Lo

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:The main objective of this work was to follow-up the development of diabetic neuropathy (DN) and its severity in patients with type 1 diabetes over 10 yr. Our intention was also to observe risk factor changes and verify which of them influence the development of neuropathy. The other objective was longitudina...

journal_title：Pediatric diabetes

authors： Hajas G,Kissova V,Tirpakova A

更新日期：2016-12-01 00:00:00