HbA1c but not diabetes duration predicts increased arterial stiffness in adolescents with poorly controlled type 1 diabetes.

abstract：:The association of type 1 diabetes mellitus (T1DM) and acute chorea is rare. We report an 8-yr-old boy with T1DM who developed acute hemichorea-hemiballism of the right arm in whom magnetic resonance imaging (MRI) of the brain revealed hyperintense signal in putamen and considerable atrophy and focal area of gliosis i...

journal_title：Pediatric diabetes

authors： Alves C,Sampaio S,Barbosa V,Machado M

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Diabetes ketoacidosis (DKA) is a common presentation and complication of type 1 diabetes (T1D). While intravenous insulin is typically used to treat acute metabolic abnormalities, the transition from intravenous to subcutaneous treatment can present a challenge. We hypothesize that co-administration of glarg...

journal_title：Pediatric diabetes

authors： Harrison VS,Rustico S,Palladino AA,Ferrara C,Hawkes CP

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:Type 1 diabetes (T1D) develops in distinct stages, before and after disease onset. Whether the natural course translates into different immunologic patterns is still uncertain. This study aimed at identifying peripheral immune patterns at key time-points, in T1D children undergoing remission phase. METHODS:C...

journal_title：Pediatric diabetes

authors： Fitas AL,Martins C,Borrego LM,Lopes L,Jörns A,Lenzen S,Limbert C

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Several intervention studies have convincingly demonstrated the importance of good glycemic control to avoid long-term diabetic complications, but the importance of other risk factors remains controversial. We previously reported a markedly reduced incidence of severe retinopathy and nephropathy during the p...

journal_title：Pediatric diabetes

authors： Nordwall M,Arnqvist HJ,Bojestig M,Ludvigsson J

更新日期：2009-05-01 00:00:00

abstract：:The Juvenile Diabetes Research Foundation International (JDRF) was founded in 1970 by parents of children with juvenile diabetes to find a cure for diabetes and its complications through the support of research. The foundation was an early supporter of stem cell research, recognizing the promise of stem cells to quick...

journal_title：Pediatric diabetes

authors： Nierras CR,Stallard J,Goldstein RA,Insel R

更新日期：2004-01-01 00:00:00

abstract：AIMS:The cardiovascular risk factor profile of a child as well as the development of body weight are influenced by genetic and childhood factors. Circulating insulin concentrations reflect the metabolic cardiovascular risk and may trigger weight gain. We aimed at identifying parental and childhood factors which may inf...

journal_title：Pediatric diabetes

authors： Brandt S,Moß A,Lennerz B,Koenig W,Weyermann M,Rothenbacher D,Brenner H,Wabitsch M

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Pediatric diabetes clinics around the world rapidly adapted care in response to COVID-19. We explored provider perceptions of care delivery adaptations and challenges for providers and patients across nine international pediatric diabetes clinics. METHODS:Providers in a quality improvement collaborative com...

journal_title：Pediatric diabetes

authors： Cristello Sarteau A,Souris KJ,Wang J,Ramadan AA,Addala A,Bowlby D,Corathers S,Forsander G,King B,Law JR,Liu W,Malik F,Pihoker C,Seid M,Smart C,Sundberg F,Tandon N,Yao M,Headley T,Mayer-Davis E

更新日期：2021-01-19 00:00:00

abstract：OBJECTIVE:Despite increased diabetes device use, few adolescents with type 1 diabetes (T1D) meet glycemic targets. We examine associations between utilization of insulin pumps and continuous glucose monitoring (CGM) and glycemic control. RESEARCH DESIGN AND METHODS:This prospective cohort study included 80 youths (10-...

journal_title：Pediatric diabetes

authors： Faulds ER,Hoffman RP,Grey M,Tan A,Tubbs-Cooley H,Militello LK,Happ MB

更新日期：2020-12-01 00:00:00

abstract：:Inactivating mutations in the pancreatic beta cell ATP-sensitive potassium (K(ATP) ) channel genes are identified by sequencing in approximately 80% of patients with diazoxide-unresponsive hyperinsulinaemic hypoglycaemia (HH). Genetic testing is clinically important as the mode of inheritance of a K(ATP) channel mutat...

journal_title：Pediatric diabetes

authors： Flanagan S,Damhuis A,Banerjee I,Rokicki D,Jefferies C,Kapoor R,Hussain K,Ellard S

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:To describe insulin pump use by youth since introduction of universal funding in Ontario, Canada and to explore the relationship between pump use and pediatric diabetes center characteristics and the relationship between discontinuation and center and patient characteristics. RESEARCH DESIGN AND METHODS:Obse...

journal_title：Pediatric diabetes

authors： Shulman R,Stukel TA,Miller FA,Newman A,Daneman D,Guttmann A

更新日期：2017-02-01 00:00:00

abstract：AIMS:Intravenous glucose tolerance testing (IVGTT) is a common test of β-cell function in which a glucose load is administered and insulin and/or C-peptide responses are monitored. Since the first IVGTT may be more stressful and stress may alter β-cell secretion or hepatic insulin extraction, we asked whether there was...

journal_title：Pediatric diabetes

authors： Ismail HM,White KS,Krischer JP,Chase HP,Cuthbertson D,Palmer JP,DPT-1 Study Group.

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Insulin pump therapy is well established in the treatment of children and adolescents with type 1 diabetes. Most studies focus on outcome parameters like hemoglobin A1c (HbA1c), hypoglycemia, and quality of life, whereas few reports address patients who discontinue pump therapy. OBJECTIVE:This survey focuse...

journal_title：Pediatric diabetes

authors： Hofer SE,Heidtmann B,Raile K,Fröhlich-Reiterer E,Lilienthal E,Berghaeuser MA,Holl RW,DPV-Science-Initiative and the German working group for insulin pump treatment in pediatric patients.

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:To assess the experiences of participants and parents of children in the oral insulin study of the Diabetes Prevention Trial - Type 1. METHOD:Before trial results were publicized, surveys were completed by 124 participants and 219 parents of children in the oral trial. RESULTS:Although most of those surveye...

journal_title：Pediatric diabetes

authors： Johnson SB,Baughcum AE,Rafkin-Mervis LE,Schatz DA,DPT-1 Study Group.

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVE:Identify and evaluate current treatment recommendations in Europe for the care of children with diabetes in view of the European Union (EU) recommendations for Reference Centers. METHODS:A questionnaire was sent in 2008 to representatives of all EU countries and Norway, all known to be actively involved in p...

journal_title：Pediatric diabetes

authors： de Beaufort C,Vazeou A,Sumnik Z,Cinek O,Hanas R,Danne T,Aschemeier B,Forsander G,SWEET group.

更新日期：2012-09-01 00:00:00

abstract：:Activating mutations in the K(ATP)-channel cause neonatal diabetes mellitus (NDM), and patients have been safely transitioned from insulin to sulfonylureas. We report a male infant with permanent NDM (PNDM), born to a PNDM mother. Blood glucose began to rise on day of life (DOL) 2, and sulfonylurea (glyburide) therapy...

journal_title：Pediatric diabetes

authors： Wambach JA,Marshall BA,Koster JC,White NH,Nichols CG

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:Patient-reported outcomes have received increased attention as treatment outcomes and indicators of wellbeing. A1c has been criticized as lacking patient-centered relevance because individuals are often unaware of their A1c, and studies also often fail to show a benefit of intensive control on quality of life...

journal_title：Pediatric diabetes

authors： Kane NS,Hoogendoorn CJ,Commissariat PV,Schulder TE,Gonzalez JS

更新日期：2020-02-01 00:00:00

abstract：:Diabetic ketoacidosis (DKA) is one of the most common causes of morbidity and mortality in new onset type 1 diabetes mellitus (T1DM). Children have a higher rate of neurological complications from DKA when compared to adults. The differential for sudden focal neurological deterioration in the setting of DKA is cerebra...

journal_title：Pediatric diabetes

authors： Finn BP,Power C,McSweeney N,Breen D,Wyse G,O'Connell SM

更新日期：2018-12-01 00:00:00

abstract：:This review highlights the evidence of linking small for gestational age (SGA) with metabolic/cardiovascular disturbances (dysmetabolic syndrome) in later life. The metabolic and cardiovascular complications associated with in utero undernutrition have been identified during the past 10 yr. Reduced fetal growth is ind...

journal_title：Pediatric diabetes

authors： Levy-Marchal C,Jaquet D

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Type 1 diabetes is an autoimmune disease occurring in genetically susceptible individuals. The precipitating cause is unclear. Recently, the Second Lebanon War exposed a large civilian population in northern Israel to significant psychological stress in the form of repeated barrages of missile attacks. HYPO...

journal_title：Pediatric diabetes

authors： Zung A,Blumenfeld O,Shehadeh N,Dally Gottfried O,Tenenbaum Rakover Y,Hershkovitz E,Gillis D,Zangen D,Pinhas-Hamiel O,Hanukoglu A,Rachmiel M,Shalitin S,Israel IDDM Registry Study Group.

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:Although insulin analogs have dramatically changed diabetes treatment, scarce evidence is available on those effects. We aimed to explore whether glycemic control had improved, the use of insulin analogs had been increased, and hypoglycemic events had decreased over time in Japanese pediatric patients with ty...

journal_title：Pediatric diabetes

authors： Mochizuki M,Kikuchi T,Urakami T,Kikuchi N,Kawamura T,Yokomichi H,Hoshino T,Matsuura N,Sasaki N,Sugihara S,Amemiya S,Japanese Study Group of Insulin Therapy for Childhood Adolescent Diabetes (JSGIT).

更新日期：2017-09-01 00:00:00

abstract：:A subgroup of diabetic patients presents with features typical of type 1 diabetes, but over months to years has variable insulin requirements and develops features of type 2 diabetes. This subgroup is referred to as atypical diabetes mellitus (ADM). Over a span of 50 yr, reports on disease epidemiology, clinical chara...

journal_title：Pediatric diabetes

authors： Egede LE,Willi SM

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:Continuous subcutaneous insulin infusion (CSII) is commonly used in patients with diabetes. Accurate and reliable delivery by insulin pumps is essential for a safe and effective therapy, particularly when using small doses. In this study, accuracy of bolus and basal rate delivery of various available insulin...

journal_title：Pediatric diabetes

authors： Ziegler R,Waldenmaier D,Kamecke U,Mende J,Haug C,Freckmann G

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:The Practice Management Committee (PMC) of the Pediatric Endocrine Society (PES) conducted a survey of its membership in February/March, 2016 to assess the current state of pediatric diabetes care delivery across multiple practice types in the United States. METHODS:The PES distributed an anonymous electron...

journal_title：Pediatric diabetes

authors： Guttmann-Bauman I,Thornton P,Adhikari S,Reifschneider K,Wood MA,Hamby T,Rubin K

更新日期：2018-08-01 00:00:00

abstract：AIM:To report C-peptide results in newly diagnosed patients and the relation to clinical diagnosis of diabetes. METHODS:A nation-wide cohort, the Better Diabetes Diagnosis study was used to determine serum C-peptide at diagnosis in 2734 children and adolescents. Clinical data were collected at diagnosis and follow-up....

journal_title：Pediatric diabetes

authors： Ludvigsson J,Carlsson A,Forsander G,Ivarsson S,Kockum I,Lernmark A,Lindblad B,Marcus C,Samuelsson U

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVE:Most youth with type 1 diabetes do not meet the American Diabetes Association (ADA) and International Society for Pediatric and Adolescent Diabetes (ISPAD) targets for hemoglobin A1c (HbA1c), blood pressure (BP), lipids, and body mass index (BMI). We hypothesized that ISPAD/ADA goal achievement would be assoc...

journal_title：Pediatric diabetes

authors： Bjornstad P,Cree-Green M,Baumgartner A,Coe G,Reyes YG,Schäfer M,Pyle L,Regensteiner JG,Reusch JE,Nadeau KJ

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:We set out to explore associations between the stool bacteriome profiles and early-onset islet autoimmunity, taking into account the interactions with the virus component of the microbiome. METHODS:Serial stool samples were longitudinally collected from 18 infants and toddlers with early-onset islet autoimm...

journal_title：Pediatric diabetes

authors： Cinek O,Kramna L,Lin J,Oikarinen S,Kolarova K,Ilonen J,Simell O,Veijola R,Autio R,Hyöty H

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:To determine the effects of omitting meal time insulin on arterial stiffness in children with type 1 diabetes. RESEARCH DESIGN AND METHODS:In this prospective, randomized, crossover study, radial artery tonometry and augmentation index adjusted to heart rate 75 (AI75 ) were used to measure arterial stiffness...

journal_title：Pediatric diabetes

authors： Meehan CS,Kethireddy PL,Ashcraft JK,Shuster JJ,Haller MJ

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:To investigate carbohydrate (CARB) and supplementary fat/protein (CFP) counting using normal and dual-wave bolus in pump therapy of children and young people with type 1 diabetes (T1D). STUDY DESIGN AND METHODS:A randomized clinical trial was conducted in 42 patients (age 6-21 yr) with T1D for at least 1 yr ...

journal_title：Pediatric diabetes

authors： Kordonouri O,Hartmann R,Remus K,Bläsig S,Sadeghian E,Danne T

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Type 1 diabetes (T1D) mellitus and obesity are recognized risk factors for cardiovascular disease (CVD). A common mechanism underlying an increased risk for endothelial dysfunction in these two metabolic diseases is oxidative stress. OBJECTIVE:To evaluate and compare the oxidant/antioxidant defense systems ...

journal_title：Pediatric diabetes

authors： Codoñer-Franch P,Pons-Morales S,Boix-García L,Valls-Bellés V

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:Mechanisms underlying the role of non-human leukocyte antigen (HLA) genetic risk variants in type 1 diabetes (T1D) are poorly understood. We aimed to test the association between methylation and non-HLA genetic risk. METHODS:We conducted a methylation quantitative trait loci (mQTL) analysis in a nested case-...

journal_title：Pediatric diabetes

authors： Carry PM,Vanderlinden LA,Johnson RK,Dong F,Steck AK,Frohnert BI,Rewers M,Yang IV,Kechris K,Norris JM

更新日期：2020-06-01 00:00:00