Abstract:
:The contributions of reduced conduction velocity (CV) and prolonged action potential duration (APD) to QT interval prolongation and T wave and T vector loop morphology in left ventricular hypertrophy (LVH) were studied using an analytical computer model. Three types of anatomic LVH were simulated: concentric and eccentric hypertrophy, and left ventricular dilatation. In each LVH type, depolarization changes were simulated by CV slowing and primary repolarization changes by APD prolongation. Both CV slowing and APD prolongation prolonged the QT interval; however, the secondary and primary repolarization changes differed in additional electrocardiogram (ECG) characteristics creating specific vectorcardiographic/ECG patterns. The secondary repolarization changes were characterized by prolonged QT interval, accompanied by pronounced QRS changes, including increased maximum spatial QRS vector magnitude, prolonged QRS duration, QRS morphology consistent with intraventricular conduction delay, lower values of the T/QRS duration ratio, increased maximum spatial T vector magnitude, narrow and prolonged discordant T vector loops, and discordant tall T waves creating a pattern of ST strain in the precordial ECG leads. QT prolongation in primary repolarization changes was accompanied with inconsiderable changes of QRS amplitude and duration, higher values of the T/QRS duration ratio, widened rounded T loops, and notched or bifid T waves in left precordial leads of the 12-lead ECG. These simulation data are consistent with the accumulated evidence suggesting that LVH induces changes in CV and APD. Our results emphasize the need for simultaneous consideration of morphologic QRS and T wave patterns together with QT prolongation in clinical evaluation of LVH.
journal_name
J Electrocardioljournal_title
Journal of electrocardiologyauthors
Bacharova L,Szathmary V,Mateasik Adoi
10.1016/j.jelectrocard.2010.07.005subject
Has Abstractpub_date
2010-11-01 00:00:00pages
624-33issue
6eissn
0022-0736issn
1532-8430pii
S0022-0736(10)00283-9journal_volume
43pub_type
杂志文章abstract:BACKGROUND:Electrocardiogram (ECG) biometrics is an advanced technology, not yet covered by guidelines on criteria, features and leads for maximal authentication accuracy. OBJECTIVE:This study aims to define the minimal set of morphological metrics in 12-lead ECG by optimization towards high reliability and security, ...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2016.07.021
更新日期:2016-01-01 00:00:00
abstract::Intracellular and extracellular recording techniques were used to study triggered activity in tissues isolated from the inferior right atrium of the dog. In the presence of norepinephrine (greater than 10(-7) M) single stimuli or short rapid pacing elicited action potentials with delayed after-depolarizations, leading...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/0022-0736(87)90005-7
更新日期:1987-01-01 00:00:00
abstract::In a 66-year-old male with subacute extensive anterior wall myocardial infarction, we report a change in ST vector orientation from a basal anterior to a mid anterior after coronary artery recanalization of the proximal left anterior descending coronary artery with rotational atherectomy. The ST vector shift on the fr...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2009.05.001
更新日期:2009-09-01 00:00:00
abstract::Successful curative treatment of right atrial tachycardia (AT) can be obtained provided detailed catheter activation mapping of the target site for radiofrequency energy application has been accomplished. However, right AT mapping may be difficult with a single roving catheter due to infrequent presence or noninducibi...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(98)90298-9
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Conflicting results have been reported on the predictive value of the electrocardiographic left ventricular hypertrophy (LVH) in the general population. This meta-analysis sought to compare the predictive value of different electrocardiographic criteria of LVH in the general population. METHODS:We comprehen...
journal_title:Journal of electrocardiology
pub_type: 杂志文章,评审
doi:10.1016/j.jelectrocard.2020.07.001
更新日期:2020-01-01 00:00:00
abstract::Ventricular fibrillation (VF) had been traditionally considered as a highly disorganized process of random electrical activity emanating from multiple, short-lived, reentrant electrical waves. It is the incessant breakup of wave fronts and the creation of new daughter waves (wavebreaks) that perpetuate VF. Other studi...
journal_title:Journal of electrocardiology
pub_type: 杂志文章,评审
doi:10.1016/j.jelectrocard.2007.06.021
更新日期:2007-11-01 00:00:00
abstract:PURPOSE:We conducted a systematic review and meta-analysis of randomized and observational studies to evaluate the associations between QRS duration (QRSd) at baseline or in follow-up and outcomes with cardiac resynchronization therapy (CRT). METHODS:We searched online databases to December 2010 and included 6 randomi...
journal_title:Journal of electrocardiology
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.jelectrocard.2012.12.003
更新日期:2013-03-01 00:00:00
abstract::Severe bradyarrythmias remain as an important cause for hospital urgent admission and these patients can suffer potentially lethal complications (such as ventricular fibrillation [VF] and torsades de pointes [TdP]) between hospital admission and final therapy. Incidence and predictors of these tachyarrhythmias have no...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2003.10.003
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Descriptions of the significance of ST segment or QRS abnormalities in myocarditis are limited because documentation of the diagnosis has previously required myocardial biopsy. Late gadolinium enhancement (LGE) and T2 weighted imaging in the midventricular wall on cardiac magnetic resonance imagi...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2014.07.018
更新日期:2014-11-01 00:00:00
abstract::A 53-year-old man with myocardial infarction was found to have frequent premature ventricular beats. The predominant pattern was classical concealed trigeminy; i.e., the number of conducted sinus beats, S, between extrasystoles satisfied the equation S = 3n + 2, where "n" is zero or any positive integer. Two other tra...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(85)80024-8
更新日期:1985-10-01 00:00:00
abstract::Although solid angle analysis has been considered to be reasonable for explaining the distribution of ST segment deviation following ischemia, it has not been tested fully, especially for ST segment changes in various sites at different lead surfaces. Thus, we investigated the applicability of solid angle theory to th...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(86)80033-4
更新日期:1986-07-01 00:00:00
abstract::In the last 10 years the molecular substrate of a diversity of primary electrical diseases has been unraveled. Disease-causing mutations in ion-channel genes have been identified and have challenged clinical and basic electrophysiologists to mechanistically link the observed genetic aberrancies to the phenotype. Indee...
journal_title:Journal of electrocardiology
pub_type: 杂志文章,评审
doi:10.1016/j.jelectrocard.2005.06.103
更新日期:2005-10-01 00:00:00
abstract::We found significant variation within each computer and cardiologist method for measurement of the ECG waveform intervals. Comparison between methods revealed that the HP system had a smaller variability than the MAC or the cardiologist, and that the MAC had a smaller variability than the cardiologist. No variability ...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(07)80110-5
更新日期:1989-01-01 00:00:00
abstract::Exercise testing was evaluated in 51 patients with critical left coronary artery disease (LCA) documented by coronary arteriography within two weeks of their bicycle ergometer (26 patients) or treadmill (25 patients) electrocardiographic study. Adequate tests, as defined by the patient having reached 85% of predicted ...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(79)80057-6
更新日期:1979-07-01 00:00:00
abstract::Catheter ablation procedures are performed by highly trained and experienced cardiology subspecialists. Yet the massive amount of data produced during these procedures creates a data overload problem that can impede the performance of even the best practitioners. This may be evidenced by (1) overlooking important sign...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(96)80063-x
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:Several studies have documented the prognostic significance of the signal-averaged electrocardiogram (SAECG) both after myocardial infarction and nonischemic cardiomyopathy. However, whether the SAECG can identify patients with implantable cardioverter-defibrillator (ICD) who receive appropriate therapy has ...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2005.08.009
更新日期:2006-04-01 00:00:00
abstract:BACKGROUND:Differentiation of wide complex tachycardias (WCTs) into ventricular tachycardia (VT) or supraventricular wide complex tachycardia (SWCT) using conventional manually-operated electrocardiogram (ECG) interpretation methods is difficult. Recent research has shown that accurate WCT differentiation may be accomp...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2020.05.004
更新日期:2020-01-01 00:00:00
abstract::The myocardial electrical conduction is significantly influenced by the sympathetic and parasympathetic nervous systems. Hypervagotonia refers to increased vagal tone leading to sinus bradycardia, sinus pause, or any degree of atrioventricular (AV) block. There are many clinical, electrocardiographic, and electrophysi...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2009.07.018
更新日期:2009-11-01 00:00:00
abstract::The purpose of the present study is to assess QT-interval measurements from the EASI 12-lead electrocardiogram (ECG) as compared with the standard 12-lead ECG. The QT interval was automatically determined in simultaneously recorded standard and EASI 12-lead ECGs, using a validated wavelet-based delineator. The agreeme...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2006.08.089
更新日期:2007-04-01 00:00:00
abstract::The ability of ECG-VCG to predict the severity of postinfarction LV asynergy was evaluated in 152 patients with previous myocardial infarction who underwent left cineventriculography in the right anterior oblique view. Various ECG and VCG signs were examined in order to predict the existence of severe asynergy in gene...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(84)81092-4
更新日期:1984-04-01 00:00:00
abstract:BACKGROUND:The appearance of a discrete upward deflection of the ST segment, termed the ST hump sign during exercise testing has been associated with resting hypertension and exaggerated blood pressure response to exercise. OBJECTIVE:We investigated the correlation between the presence of hump sign during exercise tes...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2009.09.001
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Brugada syndrome (BrS) is an inherited ion channelopathy that may predispose affected individuals to atrial cardiomyopathy. We tested the hypothesis that BrS patients have higher degrees of atrial electrophysiological abnormalities compared to controls, and these can be reflected by changes in P-wave paramet...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2019.05.005
更新日期:2019-01-01 00:00:00
abstract::The authors present a case of trifascicular block: complete right bundle branch block, tachycardia-dependent left anterior hemiblock, and bradycardia-dependent left posterior hemiblock. There is, in addition, a complicating independent AV junctional rhythm that is in most instances not affected by the conducted sinus ...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/0022-0736(89)90037-x
更新日期:1989-07-01 00:00:00
abstract::A comparison was made of the electrophysiological properties of the fibers between the previously reported conduction pathways from the left atrium to the right atrium and to the ventricle (left A-V ring pathways) and the ordinary atrial muscle, using perfused isolated rabbit hearts. Each fiber within these pathways s...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(80)80006-9
更新日期:1980-01-01 00:00:00
abstract::An interpolated premature ventricular contraction (PVC) may produce either complete block of the next sinus impulse or depression of A-V nodal conduction with a prolonged A-H interval. When a PVC results in partial depression of a A-V nodal conduction, the effect on subsequent premature atrial stimuli is unknown. The ...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(77)80025-3
更新日期:1977-01-01 00:00:00
abstract:UNLABELLED:The increased QRS voltage is considered to be a specific electrocardiogram (ECG) sign of left ventricular hypertrophy (LVH), and it is expected that the QRS voltage reflects the increase in left ventricular mass (LVM). However, the increased QRS voltage is only one of QRS patterns observed in patients with L...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2009.07.014
更新日期:2010-05-01 00:00:00
abstract::The objective of this study is to assess the performance of patient-specific segment-specific (PSSS) synthesis in QRST complexes using CAVIAR, a new method of the serial comparison for electrocardiograms and vectorcardiograms. A collection of 250 multi-lead recordings from the Common Standards for Quantitative Electro...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/0022-0736(92)90080-j
更新日期:1992-01-01 00:00:00
abstract::Reliable cardiovascular (CV) risk assessment by a noninvasive tool would be of great value for CV event prevention. The present study consists of 187 coronary artery disease patients with 8 years of follow-up. Eight vectorcardiographic parameters characterizing different aspects of ventricular repolarization were anal...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2010.05.004
更新日期:2010-07-01 00:00:00
abstract::The pathophysiological mechanisms of altered transmembrane potentials in diseased human atria were investigated in 20 patients who were divided into group A (normal) and group B (diseased). The electrophysiological data of right atrial tissues measured with glass microelectrodes included maximum diastolic potentials (...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(86)80006-1
更新日期:1986-01-01 00:00:00
abstract:INTRODUCTION:Not only repolarization, but also depolarization ECG indexes reflect the progression of ischemic injury. The aim was to assess the QRS duration and morphology dynamics during the prolonged coronary occlusion and their association with the myocardial area at risk (MaR) and final infarct size (IS). METHODS:...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2016.03.014
更新日期:2016-05-01 00:00:00